losartan has been researched along with Embolism, Fat in 2 studies
Losartan: An antagonist of ANGIOTENSIN TYPE 1 RECEPTOR with antihypertensive activity due to the reduced pressor effect of ANGIOTENSIN II.
losartan : A biphenylyltetrazole where a 1,1'-biphenyl group is attached at the 5-position and has an additional trisubstituted imidazol-1-ylmethyl group at the 4'-position
Embolism, Fat: Blocking of a blood vessel by fat deposits in the circulation. It is often seen after fractures of large bones or after administration of CORTICOSTEROIDS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In a model of fat embolism using triolein-treated rats, we have reported that the acute pulmonary histopathological changes at 48 hrs were ameliorated by the angiotensin AT1 receptor blocker losartan, the angiotensin converting enzyme inhibitor captopril, and the direct renin inhibitor aliskiren." | 1.48 | Evidence for angiotensin mediation of the late histopathological effects of pulmonary fat embolism: Protection by losartan in a rat model. ( Arif, D; Bass, D; Davis, MG; England, JP; Fletcher, A; Jain, A; Molteni, A; Poisner, A, 2018) |
| "Both captopril and losartan treatments reduced the inflammatory, vasoconstrictor, and profibrotic effects present at 48 hours (p<0." | 1.37 | Mitigating effects of captopril and losartan on lung histopathology in a rat model of fat embolism. ( Adler, F; Herndon, B; Lankachandra, K; McIff, TE; Molteni, A; Poisner, AM, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Poisner, A | 1 |
| Bass, D | 1 |
| Fletcher, A | 1 |
| Jain, A | 1 |
| England, JP | 1 |
| Davis, MG | 1 |
| Arif, D | 1 |
| Molteni, A | 2 |
| McIff, TE | 1 |
| Poisner, AM | 1 |
| Herndon, B | 1 |
| Lankachandra, K | 1 |
| Adler, F | 1 |
2 other studies available for losartan and Embolism, Fat
| Article | Year |
|---|---|
Evidence for angiotensin mediation of the late histopathological effects of pulmonary fat embolism: Protection by losartan in a rat model.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Embolism, Fat; Losartan; Lung Diseases; Rats; Reni | 2018 |
Mitigating effects of captopril and losartan on lung histopathology in a rat model of fat embolism.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Disease Models, Animal; Drug Therapy, | 2011 |