losartan has been researched along with Drug-Related Side Effects and Adverse Reactions in 9 studies
Losartan: An antagonist of ANGIOTENSIN TYPE 1 RECEPTOR with antihypertensive activity due to the reduced pressor effect of ANGIOTENSIN II.
losartan : A biphenylyltetrazole where a 1,1'-biphenyl group is attached at the 5-position and has an additional trisubstituted imidazol-1-ylmethyl group at the 4'-position
Drug-Related Side Effects and Adverse Reactions: Disorders that result from the intended use of PHARMACEUTICAL PREPARATIONS. Included in this heading are a broad variety of chemically-induced adverse conditions due to toxicity, DRUG INTERACTIONS, and metabolic effects of pharmaceuticals.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We report a rare case of life-threatening anaphylaxis after losartan use." | 8.31 | Losartan-Induced Angioedema with Acute Hypoxemic Respiratory Failure (Anaphylaxis): A Case Report. ( Kagzi, A; Kagzi, Y; Money, DB; Oxner, AZ, 2023) |
| " We report a rare case of life-threatening anaphylaxis after losartan use." | 4.31 | Losartan-Induced Angioedema with Acute Hypoxemic Respiratory Failure (Anaphylaxis): A Case Report. ( Kagzi, A; Kagzi, Y; Money, DB; Oxner, AZ, 2023) |
| " Serious adverse events were more frequent in E (2." | 2.76 | Efficacy and safety of early versus late titration of fixed-dose irbesartan/hydrochlorothiazide: ACTUAL study. ( Aoun, J; Girerd, X; Rosenbaum, D, 2011) |
| "5 million adverse drug reaction (ADR) reports for 8620 drugs/biologics that are listed for 1191 Coding Symbols for Thesaurus of Adverse Reaction (COSTAR) terms of adverse effects." | 1.32 | Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. ( Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (11.11) | 18.2507 |
| 2000's | 1 (11.11) | 29.6817 |
| 2010's | 5 (55.56) | 24.3611 |
| 2020's | 2 (22.22) | 2.80 |
| Authors | Studies |
|---|---|
| Matthews, EJ | 1 |
| Kruhlak, NL | 1 |
| Weaver, JL | 1 |
| Benz, RD | 1 |
| Contrera, JF | 1 |
| Liu, Z | 1 |
| Shi, Q | 1 |
| Ding, D | 1 |
| Kelly, R | 1 |
| Fang, H | 1 |
| Tong, W | 1 |
| Sakatis, MZ | 1 |
| Reese, MJ | 1 |
| Harrell, AW | 1 |
| Taylor, MA | 1 |
| Baines, IA | 1 |
| Chen, L | 1 |
| Bloomer, JC | 1 |
| Yang, EY | 1 |
| Ellens, HM | 1 |
| Ambroso, JL | 1 |
| Lovatt, CA | 1 |
| Ayrton, AD | 1 |
| Clarke, SE | 1 |
| Al-Oanzi, ZH | 1 |
| Kagzi, Y | 1 |
| Money, DB | 1 |
| Oxner, AZ | 1 |
| Kagzi, A | 1 |
| Machado-Alba, JE | 1 |
| Giraldo-Giraldo, C | 1 |
| Moncada-Escobar, JC | 1 |
| Arimanickam, G | 1 |
| Girerd, X | 1 |
| Rosenbaum, D | 1 |
| Aoun, J | 1 |
| Freeman, JW | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Efficacy and Safety of Irbesartan/Hydrochlorothiazide Combination: A Comparison of Active and Usual Titration Regimen in the Treatment of Hypertensive Patients Insufficiently Controlled by Monotherapy[NCT00708344] | Phase 4 | 832 participants (Actual) | Interventional | 2008-06-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for losartan and Drug-Related Side Effects and Adverse Reactions
| Article | Year |
|---|---|
Efficacy and safety of early versus late titration of fixed-dose irbesartan/hydrochlorothiazide: ACTUAL study.
Topics: Aged; Antihypertensive Agents; Blood Pressure; Drug Combinations; Drug-Related Side Effects and Adve | 2011 |
8 other studies available for losartan and Drug-Related Side Effects and Adverse Reactions
| Article | Year |
|---|---|
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Dru | 2004 |
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Da | 2011 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme | 2012 |
The effects of baicalein alone and in combination with losartan on DOX-induced nephrotoxicity in rats.
Topics: Animals; Antioxidants; Cytokines; Doxorubicin; Drug-Related Side Effects and Adverse Reactions; Flav | 2023 |
Losartan-Induced Angioedema with Acute Hypoxemic Respiratory Failure (Anaphylaxis): A Case Report.
Topics: Anaphylaxis; Angioedema; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; | 2023 |
[Active pharmacosurveillance of patients affiliated to the Colombian general social security/health system].
Topics: Adverse Drug Reaction Reporting Systems; Calcium Channel Blockers; Clopidogrel; Colombia; Diphosphon | 2010 |
Tube feeding and drugs in intensive care unit.
Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Critical Care; Delaye | 2011 |
Drug reduction in the elderly.
Topics: Aged; Aged, 80 and over; Angiotensin Receptor Antagonists; Biphenyl Compounds; Confusion; Drug Inter | 1996 |