Page last updated: 2024-10-30

losartan and Dizziness

losartan has been researched along with Dizziness in 7 studies

Losartan: An antagonist of ANGIOTENSIN TYPE 1 RECEPTOR with antihypertensive activity due to the reduced pressor effect of ANGIOTENSIN II.
losartan : A biphenylyltetrazole where a 1,1'-biphenyl group is attached at the 5-position and has an additional trisubstituted imidazol-1-ylmethyl group at the 4'-position

Dizziness: An imprecise term which may refer to a sense of spatial disorientation, motion of the environment, or lightheadedness.

Research Excerpts

ExcerptRelevanceReference
"1%) were the clinical adverse experiences most often reported in patients treated with losartan."6.68Safety and tolerability of losartan potassium, an angiotensin II receptor antagonist, compared with hydrochlorothiazide, atenolol, felodipine ER, and angiotensin-converting enzyme inhibitors for the treatment of systemic hypertension. ( Dunlay, MC; Goldberg, AI; Sweet, CS, 1995)
"Losartan is an angiotensin II receptor antagonist that is metabolized by CYP2C9 and CYP3A4 to a more potent antihypertensive metabolite, E3174."2.69The effects of fluvastatin, a CYP2C9 inhibitor, on losartan pharmacokinetics in healthy volunteers. ( Hinderliter, AL; Meadowcroft, AM; Patterson, JH; Pieper, JA; Williamson, KM, 1999)
"1%) were the clinical adverse experiences most often reported in patients treated with losartan."2.68Safety and tolerability of losartan potassium, an angiotensin II receptor antagonist, compared with hydrochlorothiazide, atenolol, felodipine ER, and angiotensin-converting enzyme inhibitors for the treatment of systemic hypertension. ( Dunlay, MC; Goldberg, AI; Sweet, CS, 1995)
"1%) were the most commonly reported clinical adverse experiences in patients treated with losartan."2.39Safety and tolerability of losartan compared with atenolol, felodipine and angiotensin converting enzyme inhibitors. ( Dunlay, MC; Goldberg, AI; Sweet, CS, 1995)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (85.71)18.2507
2000's1 (14.29)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Goldberg, AI3
Dunlay, MC2
Sweet, CS3
Terra, SG1
Ruilope, LM1
Simpson, RL1
Toh, J1
Arcuri, KE1
Meadowcroft, AM1
Williamson, KM1
Patterson, JH1
Hinderliter, AL1
Pieper, JA1
Hedner, T1
Oparil, S1
Rasmussen, K1
Rapelli, A1
Gatlin, M1
Kobi, P1
Sullivan, J1
Oddou-Stock, P1
Mann, R1
Mackay, F1
Pearce, G1
Freemantle, S1
Wilton, L1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
No Pharmacokinetic Interaction Between Chlorthalidone and Losartan, in Healthy Volunteers Under Fasting Conditions, Administered in Fixed Combination Against Individual Components Administered Jointly and Separately[NCT05090449]Phase 136 participants (Actual)Interventional2019-05-01Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for losartan and Dizziness

ArticleYear
Safety and tolerability of losartan compared with atenolol, felodipine and angiotensin converting enzyme inhibitors.
    Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1995, Volume: 13, Issue:1

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Angiotensin II Type 1 Receptor Blockers

1995

Trials

4 trials available for losartan and Dizziness

ArticleYear
Safety and tolerability of losartan potassium, an angiotensin II receptor antagonist, compared with hydrochlorothiazide, atenolol, felodipine ER, and angiotensin-converting enzyme inhibitors for the treatment of systemic hypertension.
    The American journal of cardiology, 1995, Apr-15, Volume: 75, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Conver

1995
Controlled trial of losartan given concomitantly with different doses of hydrochlorothiazide in hypertensive patients.
    Blood pressure, 1996, Volume: 5, Issue:1

    Topics: Adult; Antihypertensive Agents; Asthenia; Biphenyl Compounds; Blood Pressure; Controlled Clinical Tr

1996
The effects of fluvastatin, a CYP2C9 inhibitor, on losartan pharmacokinetics in healthy volunteers.
    Journal of clinical pharmacology, 1999, Volume: 39, Issue:4

    Topics: Adolescent; Adult; Antihypertensive Agents; Area Under Curve; Aryl Hydrocarbon Hydroxylases; Blood P

1999
A comparison of the angiotensin II antagonists valsartan and losartan in the treatment of essential hypertension.
    American journal of hypertension, 1999, Volume: 12, Issue:4 Pt 1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Angiotensin Receptor Antagonists; Antihypertensive Agent

1999

Other Studies

2 other studies available for losartan and Dizziness

ArticleYear
Cardiology patient page. Angiotensin receptor blockers.
    Circulation, 2003, Jun-24, Volume: 107, Issue:24

    Topics: Acrylates; Angiotensin Receptor Antagonists; Antihypertensive Agents; Benzimidazoles; Benzoates; Bip

2003
Losartan: a study of pharmacovigilance data on 14,522 patients.
    Journal of human hypertension, 1999, Volume: 13, Issue:8

    Topics: Age Distribution; Aged; Antihypertensive Agents; Cohort Studies; Cough; Dizziness; Female; Humans; I

1999