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losartan and Dehydration

losartan has been researched along with Dehydration in 15 studies

Losartan: An antagonist of ANGIOTENSIN TYPE 1 RECEPTOR with antihypertensive activity due to the reduced pressor effect of ANGIOTENSIN II.
losartan : A biphenylyltetrazole where a 1,1'-biphenyl group is attached at the 5-position and has an additional trisubstituted imidazol-1-ylmethyl group at the 4'-position

Dehydration: The condition that results from excessive loss of water from a living organism.

Research Excerpts

ExcerptRelevanceReference
"The objective of this study was to provide for the first time data on plasma catecholamines, cortisol, glutathione and malondialdehyde after long term dehydration (20 days) in the presence and absence of angiotensin II (Ang II) AT1 receptor blocker (losartan) versus levels in time-matched, non-dehydrated control camels and to record the responses of glutathione and malondialdehyde activity in liver and kidney homogenates in control, dehydrated-losartan treated and dehydrated camels."3.79Effects of dehydration and blockade of angiotensin II AT1 receptor on stress hormones and anti-oxidants in the one-humped camel. ( Adem, A; Ali, MA; Amir, N; Kazzam, E; Nyberg, F, 2013)
"Our objectives were to compare the levels of circulating electrolytes, hormones, and renal function during 20 days of dehydration in camels versus the level in non-dehydrated camels and to record the effect of blocking angiotensin II AT1 receptors with losartan during dehydration."3.78Responses to dehydration in the one-humped camel and effects of blocking the renin-angiotensin system. ( Adem, A; Ali, MA; Benedict, S; Chandranath, IS; Frampton, CM; Kazzam, E; Lewis, LK; Nagelkerke, N; Nicholls, GM; Nyberg, F; Pathan, JY; Yandle, TG, 2012)
"Losartan-treated camels also exhibited a significant decline in ANP and BNP levels across 20 days of dehydration but the changes were not different from those seen with dehydration alone."1.39ANP and BNP responses to dehydration in the one-humped camel and effects of blocking the renin-angiotensin system. ( Adem, A; Al Haj, M; Benedict, S; Frampton, CM; Kazzam, E; Lewis, LK; Nagelkerke, N; Nicholls, MG; Nyberg, F; Yandle, TG; Yasin, J, 2013)
"Thus, the dehydration-induced switch in control of tSNA from hypothalamus to cNTS seems to be mediated via activation of AP1 transcription factors in the cNTS."1.37Switching control of sympathetic activity from forebrain to hindbrain in chronic dehydration. ( Antunes, VR; Colombari, DS; Colombari, E; Ferguson, AV; Freiria-Oliveira, AH; Fry, M; Hindmarch, C; Murphy, D; Paton, JF; Yao, ST, 2011)
"Pretreatment with indomethacin (200 microg/5 microl; icv), an inhibitor of cyclo-oxygenase, significantly attenuated the ANG II-induced increase in oxytocin secretion only."1.31Central interactions between angiotensin II and PGD(2) in the regulation of vasopressin and oxytocin secretion in dehydrated rats. ( Bui, V; Kadekaro, M; Summy-Long, JY; Terrell, ML, 2001)
"Thus, the thirst evoked by cellular dehydration, as well as the thirst evoked by extracellular dehydration, may be mediated by angiotensin II."1.29Thirst induced by increasing brain sodium concentration is mediated by brain angiotensin. ( Blair-West, JR; Burns, P; Denton, DA; Ferraro, T; McBurnie, MI; Tarjan, E; Weisinger, RS, 1994)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (33.33)18.2507
2000's5 (33.33)29.6817
2010's5 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Han, S1
Jeong, AL1
Lee, S1
Park, JS1
Buyanravjikh, S1
Kang, W1
Choi, S1
Park, C1
Han, J1
Son, WC1
Yoo, KH1
Cheong, JH1
Oh, GT1
Lee, WY1
Kim, J1
Suh, SH1
Lee, SH1
Lim, JS1
Lee, MS1
Yang, Y1
Adem, A3
Al Haj, M1
Benedict, S2
Yasin, J1
Nagelkerke, N2
Nyberg, F3
Yandle, TG2
Frampton, CM2
Lewis, LK2
Nicholls, MG1
Kazzam, E3
Ali, MA2
Amir, N1
Colombari, DS1
Colombari, E1
Freiria-Oliveira, AH1
Antunes, VR1
Yao, ST1
Hindmarch, C1
Ferguson, AV1
Fry, M1
Murphy, D1
Paton, JF1
Chandranath, IS1
Pathan, JY1
Nicholls, GM1
Miyoshi, M1
Nagata, K1
Imoto, T1
Goto, O1
Ishida, A1
Watanabe, T1
Schwimmer, H1
Gerstberger, R1
Horowitz, M1
Blair-West, JR3
Burns, P1
Denton, DA3
Ferraro, T1
McBurnie, MI1
Tarjan, E2
Weisinger, RS3
Gambaryan, S1
Häusler, C1
Markert, T1
Pöhler, D1
Jarchau, T1
Walter, U1
Haase, W1
Kurtz, A1
Lohmann, SM1
McKinley, MJ1
Morris, M1
Li, P1
Callahan, MF1
Oliverio, MI1
Coffman, TM1
Bosch, SM1
Diz, DI1
Bonnet, JM1
Boivin, R1
Bernard, N1
Sassard, J1
Kadekaro, M2
Terrell, ML2
Liu, H1
Bui, V2
Summy-Long, JY2

Other Studies

15 other studies available for losartan and Dehydration

ArticleYear
C1q/TNF-α-Related Protein 1 (CTRP1) Maintains Blood Pressure Under Dehydration Conditions.
    Circulation research, 2018, 08-17, Volume: 123, Issue:5

    Topics: Adipokines; Angiotensin II Type 1 Receptor Blockers; Animals; Blood Pressure; Cell Line; Cells, Cult

2018
ANP and BNP responses to dehydration in the one-humped camel and effects of blocking the renin-angiotensin system.
    PloS one, 2013, Volume: 8, Issue:3

    Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Atrial Natriuretic Factor; Camelus; Dehydration; L

2013
Effects of dehydration and blockade of angiotensin II AT1 receptor on stress hormones and anti-oxidants in the one-humped camel.
    BMC veterinary research, 2013, Nov-19, Volume: 9

    Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Antioxidants; Camelus; Catecholamines; Dehydration

2013
Switching control of sympathetic activity from forebrain to hindbrain in chronic dehydration.
    The Journal of physiology, 2011, Sep-15, Volume: 589, Issue:Pt 18

    Topics: Animals; Antihypertensive Agents; Blood Pressure; Chronic Disease; Dehydration; Hypothalamus; Losart

2011
Responses to dehydration in the one-humped camel and effects of blocking the renin-angiotensin system.
    PloS one, 2012, Volume: 7, Issue:5

    Topics: Aldosterone; Analysis of Variance; Animals; Arginine Vasopressin; Body Weights and Measures; Camelus

2012
ANG II is involved in the LPS-induced production of proinflammatory cytokines in dehydrated rats.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2003, Volume: 284, Issue:4

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals;

2003
Nitric oxide and angiotensin II: neuromodulation of thermoregulation during combined heat and hypohydration stress.
    Brain research, 2004, May-01, Volume: 1006, Issue:2

    Topics: Analysis of Variance; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2

2004
Thirst induced by increasing brain sodium concentration is mediated by brain angiotensin.
    Brain research, 1994, Feb-21, Volume: 637, Issue:1-2

    Topics: Angiotensin II; Animals; Biphenyl Compounds; Brain Chemistry; Cattle; Dehydration; Drinking; Female;

1994
Expression of type II cGMP-dependent protein kinase in rat kidney is regulated by dehydration and correlated with renin gene expression.
    The Journal of clinical investigation, 1996, Aug-01, Volume: 98, Issue:3

    Topics: Animals; Atrial Natriuretic Factor; Base Sequence; Biphenyl Compounds; Chlorides; Cyclic GMP-Depende

1996
Central infusion of the AT1 receptor antagonist losartan inhibits thirst but not sodium appetite in cattle.
    The American journal of physiology, 1997, Volume: 272, Issue:6 Pt 2

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Appetite; Behavior, Animal; Biphenyl Comp

1997
Role of brain angiotensin II in thirst and sodium appetite of sheep.
    The American journal of physiology, 1997, Volume: 273, Issue:1 Pt 2

    Topics: Analysis of Variance; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Appetite; Biphenyl

1997
Neuroendocrine effects of dehydration in mice lacking the angiotensin AT1a receptor.
    Hypertension (Dallas, Tex. : 1979), 1999, Volume: 33, Issue:1 Pt 2

    Topics: Angiotensin II; Animals; Autoradiography; Brain; Dehydration; Iodine Radioisotopes; Losartan; Male;

1999
Extrarenal renin-angiotensin systems are unable to maintain blood pressure in sheep.
    Clinical and experimental pharmacology & physiology, 2000, Volume: 27, Issue:9

    Topics: Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Dehydration; Fem

2000
Indomethacin prevents the L-NAME-induced increase in plasma levels of oxytocin in dehydrated rats.
    Brain research, 2000, Sep-22, Volume: 877, Issue:2

    Topics: Angiotensin II; Animals; Dehydration; Hypothalamo-Hypophyseal System; Indomethacin; Injections, Intr

2000
Central interactions between angiotensin II and PGD(2) in the regulation of vasopressin and oxytocin secretion in dehydrated rats.
    Brain research, 2001, Jan-19, Volume: 889, Issue:1-2

    Topics: Angiotensin II; Animals; Antihypertensive Agents; Brain Chemistry; Central Nervous System; Cyclooxyg

2001