Page last updated: 2024-10-30

losartan and Complications, Pregnancy

losartan has been researched along with Complications, Pregnancy in 5 studies

Losartan: An antagonist of ANGIOTENSIN TYPE 1 RECEPTOR with antihypertensive activity due to the reduced pressor effect of ANGIOTENSIN II.
losartan : A biphenylyltetrazole where a 1,1'-biphenyl group is attached at the 5-position and has an additional trisubstituted imidazol-1-ylmethyl group at the 4'-position

Research Excerpts

ExcerptRelevanceReference
"We describe the reversal of losartan-induced oligohydramnios at 27 weeks of gestation with subsequent development of fetal thrombosis and possible mechanism of action for this extremely rare in utero complication."7.73In utero losartan withdrawal and subsequent development of fetal inferior vena cava thrombosis. ( Bakkum, JN; Brost, BC; Johansen, KL; Johnston, BW; Watson, WJ, 2006)
" She had been taking losartan tablets before and during pregnancy."4.02Use of angiotensin II receptor blocker during pregnancy: A case report. ( Duan, MF; Huang, N; Song, CR; Wang, YM; Wei, Q; Zhang, L, 2021)
"We describe the reversal of losartan-induced oligohydramnios at 27 weeks of gestation with subsequent development of fetal thrombosis and possible mechanism of action for this extremely rare in utero complication."3.73In utero losartan withdrawal and subsequent development of fetal inferior vena cava thrombosis. ( Bakkum, JN; Brost, BC; Johansen, KL; Johnston, BW; Watson, WJ, 2006)
"In studies of dementias and Alzheimer's disease (AD), some studies have shown that antihypertensive drugs, including angiotensin-converting enzyme inhibitors, have some moderate effects on cognitive decline, but that the angiotensin receptor antagonist losartan has a significantly beneficial effect."2.42Angiotensin as a target for the treatment of Alzheimer's disease, anxiety and depression. ( Gard, PR, 2004)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (20.00)18.2507
2000's3 (60.00)29.6817
2010's0 (0.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Wei, Q1
Zhang, L1
Duan, MF1
Wang, YM1
Huang, N1
Song, CR1
Gard, PR1
Habashi, JP1
Judge, DP1
Holm, TM1
Cohn, RD1
Loeys, BL1
Cooper, TK1
Myers, L1
Klein, EC1
Liu, G1
Calvi, C1
Podowski, M1
Neptune, ER1
Halushka, MK1
Bedja, D1
Gabrielson, K1
Rifkin, DB1
Carta, L1
Ramirez, F1
Huso, DL1
Dietz, HC1
Bakkum, JN1
Brost, BC1
Johansen, KL1
Johnston, BW1
Watson, WJ1
Mann, R1
Mackay, F1
Pearce, G1
Freemantle, S1
Wilton, L1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effects of Losartan vs. Nebivolol vs. the Association of Both on the Progression of Aortic Root Dilation in Marfan Syndrome (MFS) With FBN1 Gene Mutations.[NCT00683124]Phase 3291 participants (Anticipated)Interventional2008-07-31Recruiting
No Pharmacokinetic Interaction Between Chlorthalidone and Losartan, in Healthy Volunteers Under Fasting Conditions, Administered in Fixed Combination Against Individual Components Administered Jointly and Separately[NCT05090449]Phase 136 participants (Actual)Interventional2019-05-01Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for losartan and Complications, Pregnancy

ArticleYear
Angiotensin as a target for the treatment of Alzheimer's disease, anxiety and depression.
    Expert opinion on therapeutic targets, 2004, Volume: 8, Issue:1

    Topics: Aging; Alzheimer Disease; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inh

2004

Other Studies

4 other studies available for losartan and Complications, Pregnancy

ArticleYear
Use of angiotensin II receptor blocker during pregnancy: A case report.
    Medicine, 2021, Jan-22, Volume: 100, Issue:3

    Topics: Adult; Angiotensin Receptor Antagonists; Female; Humans; Losartan; Nephrotic Syndrome; Oligohydramni

2021
Losartan, an AT1 antagonist, prevents aortic aneurysm in a mouse model of Marfan syndrome.
    Science (New York, N.Y.), 2006, Apr-07, Volume: 312, Issue:5770

    Topics: Adrenergic beta-Antagonists; Angiotensin II Type 1 Receptor Blockers; Animals; Antibodies; Aorta; Ao

2006
In utero losartan withdrawal and subsequent development of fetal inferior vena cava thrombosis.
    Obstetrics and gynecology, 2006, Volume: 108, Issue:3 Pt 2

    Topics: Angiotensin II Type 1 Receptor Blockers; Contraindications; Diabetes Mellitus, Type 2; Female; Fetal

2006
Losartan: a study of pharmacovigilance data on 14,522 patients.
    Journal of human hypertension, 1999, Volume: 13, Issue:8

    Topics: Age Distribution; Aged; Antihypertensive Agents; Cohort Studies; Cough; Dizziness; Female; Humans; I

1999