losartan has been researched along with Choline Deficiency in 2 studies
Losartan: An antagonist of ANGIOTENSIN TYPE 1 RECEPTOR with antihypertensive activity due to the reduced pressor effect of ANGIOTENSIN II.
losartan : A biphenylyltetrazole where a 1,1'-biphenyl group is attached at the 5-position and has an additional trisubstituted imidazol-1-ylmethyl group at the 4'-position
Choline Deficiency: A condition produced by a deficiency of CHOLINE in animals. Choline is known as a lipotropic agent because it has been shown to promote the transport of excess fat from the liver under certain conditions in laboratory animals. Combined deficiency of choline (included in the B vitamin complex) and all other methyl group donors causes liver cirrhosis in some animals. Unlike compounds normally considered as vitamins, choline does not serve as a cofactor in enzymatic reactions. (From Saunders Dictionary & Encyclopedia of Laboratory Medicine and Technology, 1984)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Nonalcoholic steatohepatitis (NASH) is a metabolic disorder of the liver that may evolve into fibrosis or cirrhosis." | 1.34 | Effect of losartan on early liver fibrosis development in a rat model of nonalcoholic steatohepatitis. ( Accatino, L; Aguayo, G; Arrese, M; Duarte, I; Ibañez, P; Miquel, JF; Pizarro, M; Solis, N, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kaji, K | 1 |
| Yoshiji, H | 1 |
| Kitade, M | 1 |
| Ikenaka, Y | 1 |
| Noguchi, R | 1 |
| Shirai, Y | 1 |
| Aihara, Y | 1 |
| Namisaki, T | 1 |
| Yoshii, J | 1 |
| Yanase, K | 1 |
| Tsujimoto, T | 1 |
| Kawaratani, H | 1 |
| Fukui, H | 1 |
| Ibañez, P | 1 |
| Solis, N | 1 |
| Pizarro, M | 1 |
| Aguayo, G | 1 |
| Duarte, I | 1 |
| Miquel, JF | 1 |
| Accatino, L | 1 |
| Arrese, M | 1 |
2 other studies available for losartan and Choline Deficiency
| Article | Year |
|---|---|
Combination treatment of angiotensin II type I receptor blocker and new oral iron chelator attenuates progression of nonalcoholic steatohepatitis in rats.
Topics: Administration, Oral; Angiogenesis Inhibitors; Angiotensin II; Angiotensin II Type 1 Receptor Blocke | 2011 |
Effect of losartan on early liver fibrosis development in a rat model of nonalcoholic steatohepatitis.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Choline Deficiency; Disease Models, Animal; Fatty | 2007 |