losartan has been researched along with Cholestasis in 1 studies
Losartan: An antagonist of ANGIOTENSIN TYPE 1 RECEPTOR with antihypertensive activity due to the reduced pressor effect of ANGIOTENSIN II.
losartan : A biphenylyltetrazole where a 1,1'-biphenyl group is attached at the 5-position and has an additional trisubstituted imidazol-1-ylmethyl group at the 4'-position
Cholestasis: Impairment of bile flow due to obstruction in small bile ducts (INTRAHEPATIC CHOLESTASIS) or obstruction in large bile ducts (EXTRAHEPATIC CHOLESTASIS).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Losartan 4 mg/kg/day did not increase renal sodium excretion in this model of liver cirrhosis, although the urinary ANGII excretion was increased." | 7.88 | Activation of RAAS in a rat model of liver cirrhosis: no effect of losartan on renal sodium excretion. ( Bie, P; Fialla, AD; Schaffalitzky de Muckadell, OB; Thiesson, HC, 2018) |
| "Losartan 4 mg/kg/day did not increase renal sodium excretion in this model of liver cirrhosis, although the urinary ANGII excretion was increased." | 3.88 | Activation of RAAS in a rat model of liver cirrhosis: no effect of losartan on renal sodium excretion. ( Bie, P; Fialla, AD; Schaffalitzky de Muckadell, OB; Thiesson, HC, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fialla, AD | 1 |
| Schaffalitzky de Muckadell, OB | 1 |
| Bie, P | 1 |
| Thiesson, HC | 1 |
1 other study available for losartan and Cholestasis
| Article | Year |
|---|---|
Activation of RAAS in a rat model of liver cirrhosis: no effect of losartan on renal sodium excretion.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Cholestasis; Disease Models, Animal; Kidney; Liver | 2018 |