losartan has been researched along with Bradycardia in 14 studies
Losartan: An antagonist of ANGIOTENSIN TYPE 1 RECEPTOR with antihypertensive activity due to the reduced pressor effect of ANGIOTENSIN II.
losartan : A biphenylyltetrazole where a 1,1'-biphenyl group is attached at the 5-position and has an additional trisubstituted imidazol-1-ylmethyl group at the 4'-position
Bradycardia: Cardiac arrhythmias that are characterized by excessively slow HEART RATE, usually below 50 beats per minute in human adults. They can be classified broadly into SINOATRIAL NODE dysfunction and ATRIOVENTRICULAR BLOCK.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The selective angiotensin (ANG) II antagonists losartan (AT1) and CGP-42112A (AT2) were used to determine the receptor subtype and neuronal pathways that mediate the hypotension and bradycardia produced by 200 fmol of ANG II microinjected into the dorsal medial nucleus tractus solitarii (NTS) or dorsal motor nucleus of the vagus (dmnX) in anesthetized rats." | 3.69 | Mechanisms of angiotensin-induced hypotension and bradycardia in the medial solitary tract nucleus. ( Averill, DB; Barnes, KL; Fow, JE, 1994) |
| "5." | 1.29 | Angiotensin II activates pressor and depressor sites of the pontomedulla that react to glutamate. ( Chai, CY; Chen, SY; Lin, AM; Tseng, CJ, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (28.57) | 18.2507 |
| 2000's | 6 (42.86) | 29.6817 |
| 2010's | 3 (21.43) | 24.3611 |
| 2020's | 1 (7.14) | 2.80 |
| Authors | Studies |
|---|---|
| Lima, TC | 1 |
| Barbosa, MA | 1 |
| Costa, DC | 1 |
| Becker, LK | 1 |
| Cardoso, LM | 2 |
| Alzamora, AC | 3 |
| Yamaki, F | 1 |
| Arai, T | 1 |
| Aoyama, M | 1 |
| Watanabe, A | 1 |
| Takata, Y | 1 |
| Gómez Casal, V | 1 |
| Lage Cendon, L | 1 |
| Lago Preciado, G | 1 |
| Vara Adrio, S | 1 |
| Sá, RW | 1 |
| Haibara, AS | 1 |
| Gomes, PM | 1 |
| Aguiar, GL | 1 |
| Nascimento, RS | 1 |
| Pedrosa, ML | 1 |
| de Oliveira, LB | 1 |
| Cangussu, LM | 1 |
| de Castro, UG | 1 |
| do Pilar Machado, R | 1 |
| Silva, ME | 1 |
| Ferreira, PM | 1 |
| dos Santos, RA | 2 |
| Campagnole-Santos, MJ | 1 |
| Giancaspro, G | 1 |
| Suppa, M | 1 |
| Genuini, I | 1 |
| Caselli, S | 1 |
| Fedele, F | 1 |
| Kinugawa, S | 1 |
| Post, H | 1 |
| Kaminski, PM | 1 |
| Zhang, X | 1 |
| Xu, X | 1 |
| Huang, H | 1 |
| Recchia, FA | 1 |
| Ochoa, M | 1 |
| Wolin, MS | 1 |
| Kaley, G | 1 |
| Hintze, TH | 1 |
| de Moura, MM | 1 |
| Fontes, MA | 1 |
| Prabhakar, H | 1 |
| Rath, GP | 1 |
| Arora, R | 1 |
| Fow, JE | 1 |
| Averill, DB | 1 |
| Barnes, KL | 1 |
| Chai, CY | 1 |
| Chen, SY | 1 |
| Lin, AM | 1 |
| Tseng, CJ | 1 |
| Du, XJ | 1 |
| Cox, HS | 1 |
| Dart, AM | 1 |
| Esler, MD | 1 |
| Paton, JF | 1 |
| Kasparov, S | 1 |
| Farah, VM | 1 |
| Moreira, ED | 1 |
| Ushizima, M | 1 |
| Cestari, IA | 1 |
| Irigoyen, MC | 1 |
| Krieger, EM | 1 |
14 other studies available for losartan and Bradycardia
| Article | Year |
|---|---|
Fitness is improved by adjustments in muscle intracellular signaling in rats with renovascular hypertension 2K1C undergoing voluntary physical exercise.
Topics: Animals; Baroreflex; Blood Pressure; Bradycardia; Disease Models, Animal; Heart Rate; Hypertension, | 2020 |
Angiotensin AT(1)-receptor blockers enhance cardiac responses to parasympathetic nerve stimulation via presynaptic AT(1) receptors in pithed rats.
Topics: Acetylcholine; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Recept | 2013 |
[Ivabradine poisoning with suicide intention].
Topics: Adult; Antidotes; Benzazepines; Bradycardia; Calcium Gluconate; Combined Modality Therapy; Drug Over | 2015 |
Changes in cardiovascular responses to chemoreflex activation of rats recovered from protein restriction are not related to AT
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Arterial Pressure; Bradycardia; Ca | 2017 |
Angiotensin-(1-7) antagonist, A-779, microinjection into the caudal ventrolateral medulla of renovascular hypertensive rats restores baroreflex bradycardia.
Topics: Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Baroreflex; Blood Pressure; Bradyca | 2009 |
Syncope caused by iatrogenic hyperkalemia.
Topics: Aged, 80 and over; Angiotensin II Type 1 Receptor Blockers; Bradycardia; Cardiac Pacing, Artificial; | 2009 |
Coronary microvascular endothelial stunning after acute pressure overload in the conscious dog is caused by oxidant processes: the role of angiotensin II type 1 receptor and NAD(P)H oxidase.
Topics: Acetophenones; Angiotensin II; Animals; Ascorbic Acid; Bradycardia; Bradykinin; Coronary Circulation | 2003 |
Evidence for a functional cardiac interaction between losartan and angiotensin-(1-7) receptors revealed by orthostatic tilting test in rats.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin Receptor Antagonists; Animals; | 2005 |
Sudden cardiac standstill during skin flap elevation in a patient undergoing craniotomy.
Topics: Aged; Amlodipine; Anesthesia, General; Anti-Arrhythmia Agents; Antihypertensive Agents; Atropine; Bl | 2007 |
Mechanisms of angiotensin-induced hypotension and bradycardia in the medial solitary tract nucleus.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Bradycardia; Cardiova | 1994 |
Angiotensin II activates pressor and depressor sites of the pontomedulla that react to glutamate.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Bradycardia; C | 1996 |
Depression of efferent parasympathetic control of heart rate in rats with myocardial infarction: effect of losartan.
Topics: Acetylcholine; Animals; Anti-Arrhythmia Agents; Blood Pressure; Bradycardia; Heart Rate; Losartan; M | 1998 |
Differential effects of angiotensin II on cardiorespiratory reflexes mediated by nucleus tractus solitarii - a microinjection study in the rat.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Bradycardia; Chemoreceptor Cells; Heart R | 1999 |
Acute AT1 receptor blockade does not improve the depressed baroreflex in rats with chronic renal hypertension.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Baroreflex; Brad | 2000 |