losartan has been researched along with Birth Weight in 2 studies
Losartan: An antagonist of ANGIOTENSIN TYPE 1 RECEPTOR with antihypertensive activity due to the reduced pressor effect of ANGIOTENSIN II.
losartan : A biphenylyltetrazole where a 1,1'-biphenyl group is attached at the 5-position and has an additional trisubstituted imidazol-1-ylmethyl group at the 4'-position
Birth Weight: The mass or quantity of heaviness of an individual at BIRTH. It is expressed by units of pounds or kilograms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We found: (1) comparable birth weights in control and PD123319-treated animals, but reduced body weight in newborn losartan-treated animals; (2) compared to untreated animals, type I collagen and TGF-beta 1 mRNA expression in cardiac tissue were each equally reduced in both losartan and PD123319-treated animals; (3) increased type III collagen mRNA expression in both PD123319- and losartan-treated groups; and (4) a significant decrease in total soluble cardiac collagen concentration in both losartan and PD123319-treated groups, confirmed by attenuated immunoreactivity of type I and III collagens in whole heart extracts by Western blotting." | 3.70 | Angiotensin II receptor blockade during gestation attenuates collagen formation in the developing rat heart. ( Lamparter, S; Sun, Y; Weber, KT, 1999) |
| "Losartan treatment for three weeks lowered systolic blood pressure in both Control and Restricted groups but this difference was not sustained after the cessation of treatment." | 1.48 | Angiotensin receptor blockade in juvenile male rat offspring: Implications for long-term cardio-renal health. ( Gallo, LA; Mazzuca, MQ; Moritz, KM; Parkington, HC; Tare, M; Walton, SL; Wlodek, ME, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Walton, SL | 1 |
| Mazzuca, MQ | 1 |
| Tare, M | 1 |
| Parkington, HC | 1 |
| Wlodek, ME | 1 |
| Moritz, KM | 1 |
| Gallo, LA | 1 |
| Lamparter, S | 1 |
| Sun, Y | 1 |
| Weber, KT | 1 |
2 other studies available for losartan and Birth Weight
| Article | Year |
|---|---|
Angiotensin receptor blockade in juvenile male rat offspring: Implications for long-term cardio-renal health.
Topics: Age Factors; Angiotensin II Type 1 Receptor Blockers; Animals; Animals, Newborn; Birth Weight; Blood | 2018 |
Angiotensin II receptor blockade during gestation attenuates collagen formation in the developing rat heart.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Birth Weight; Blotting, Western; Collagen | 1999 |