losartan has been researched along with B16 Melanoma in 3 studies
Losartan: An antagonist of ANGIOTENSIN TYPE 1 RECEPTOR with antihypertensive activity due to the reduced pressor effect of ANGIOTENSIN II.
losartan : A biphenylyltetrazole where a 1,1'-biphenyl group is attached at the 5-position and has an additional trisubstituted imidazol-1-ylmethyl group at the 4'-position
| Excerpt | Relevance | Reference |
|---|---|---|
| "We evaluated the involvement of angiotensin II (AngII)-dependent pathways in melanoma growth, through the pharmacological blockage of AT1 receptor by the anti-hypertensive drug losartan (LOS)." | 3.76 | Inhibition of angiotensin II receptor 1 limits tumor-associated angiogenesis and attenuates growth of murine melanoma. ( Chammas, R; Freitas, HC; Fujihara, CK; Machado, CM; Mattar, AL; Nonogaki, S; Otake, AH; Zatz, R, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yu, M | 1 |
| Zhang, C | 1 |
| Tang, Z | 1 |
| Tang, X | 1 |
| Xu, H | 1 |
| Durymanov, MO | 1 |
| Yarutkin, AV | 1 |
| Bagrov, DV | 1 |
| Klinov, DV | 1 |
| Kedrov, AV | 1 |
| Chemeris, NK | 1 |
| Rosenkranz, AA | 1 |
| Sobolev, AS | 1 |
| Otake, AH | 1 |
| Mattar, AL | 1 |
| Freitas, HC | 1 |
| Machado, CM | 1 |
| Nonogaki, S | 1 |
| Fujihara, CK | 1 |
| Zatz, R | 1 |
| Chammas, R | 1 |
3 other studies available for losartan and B16 Melanoma
| Article | Year |
|---|---|
Intratumoral injection of gels containing losartan microspheres and (PLG-g-mPEG)-cisplatin nanoparticles improves drug penetration, retention and anti-tumor activity.
Topics: Animals; Antineoplastic Agents; Cisplatin; Drug Carriers; Drug Compounding; Drug Liberation; Fibrill | 2019 |
Application of vasoactive and matrix-modifying drugs can improve polyplex delivery to tumors upon intravenous administration.
Topics: Administration, Intravenous; Angiotensin II; Animals; Cell Line, Tumor; Collagen Type I; DNA; Drug D | 2016 |
Inhibition of angiotensin II receptor 1 limits tumor-associated angiogenesis and attenuates growth of murine melanoma.
Topics: Angiogenic Proteins; Angiotensin II Type 1 Receptor Blockers; Animals; Cell Line, Tumor; Female; Hum | 2010 |