losartan has been researched along with Autosomal Dominant Juvenile Parkinson Disease in 2 studies
Losartan: An antagonist of ANGIOTENSIN TYPE 1 RECEPTOR with antihypertensive activity due to the reduced pressor effect of ANGIOTENSIN II.
losartan : A biphenylyltetrazole where a 1,1'-biphenyl group is attached at the 5-position and has an additional trisubstituted imidazol-1-ylmethyl group at the 4'-position
Excerpt | Relevance | Reference |
---|---|---|
" Losartan carboxylic acid (LCA), the potent AT1 blocker metabolite of losartan, suffers from poor bioavailability and brain access." | 1.48 | Conjugation to Ascorbic Acid Enhances Brain Availability of Losartan Carboxylic Acid and Protects Against Parkinsonism in Rats. ( Prusty, S; Sahu, PK; Singh, VK; Subudhi, BB, 2018) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 1 (50.00) | 29.6817 |
2010's | 1 (50.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Subudhi, BB | 1 |
Sahu, PK | 1 |
Singh, VK | 1 |
Prusty, S | 1 |
Grammatopoulos, TN | 1 |
Ahmadi, F | 1 |
Jones, SM | 1 |
Fariss, MW | 1 |
Weyhenmeyer, JA | 1 |
Zawada, WM | 1 |
2 other studies available for losartan and Autosomal Dominant Juvenile Parkinson Disease
Article | Year |
---|---|
Conjugation to Ascorbic Acid Enhances Brain Availability of Losartan Carboxylic Acid and Protects Against Parkinsonism in Rats.
Topics: Administration, Oral; Angiotensin II Type 1 Receptor Blockers; Animals; Ascorbic Acid; Behavior, Ani | 2018 |
Angiotensin II protects cultured midbrain dopaminergic neurons against rotenone-induced cell death.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antioxidants; Cell Death; Cells, C | 2005 |