Page last updated: 2024-10-30

losartan and Autosomal Dominant Juvenile Parkinson Disease

losartan has been researched along with Autosomal Dominant Juvenile Parkinson Disease in 2 studies

Losartan: An antagonist of ANGIOTENSIN TYPE 1 RECEPTOR with antihypertensive activity due to the reduced pressor effect of ANGIOTENSIN II.
losartan : A biphenylyltetrazole where a 1,1'-biphenyl group is attached at the 5-position and has an additional trisubstituted imidazol-1-ylmethyl group at the 4'-position

Research Excerpts

ExcerptRelevanceReference
" Losartan carboxylic acid (LCA), the potent AT1 blocker metabolite of losartan, suffers from poor bioavailability and brain access."1.48Conjugation to Ascorbic Acid Enhances Brain Availability of Losartan Carboxylic Acid and Protects Against Parkinsonism in Rats. ( Prusty, S; Sahu, PK; Singh, VK; Subudhi, BB, 2018)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Subudhi, BB1
Sahu, PK1
Singh, VK1
Prusty, S1
Grammatopoulos, TN1
Ahmadi, F1
Jones, SM1
Fariss, MW1
Weyhenmeyer, JA1
Zawada, WM1

Other Studies

2 other studies available for losartan and Autosomal Dominant Juvenile Parkinson Disease

ArticleYear
Conjugation to Ascorbic Acid Enhances Brain Availability of Losartan Carboxylic Acid and Protects Against Parkinsonism in Rats.
    The AAPS journal, 2018, 10-22, Volume: 20, Issue:6

    Topics: Administration, Oral; Angiotensin II Type 1 Receptor Blockers; Animals; Ascorbic Acid; Behavior, Ani

2018
Angiotensin II protects cultured midbrain dopaminergic neurons against rotenone-induced cell death.
    Brain research, 2005, May-31, Volume: 1045, Issue:1-2

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antioxidants; Cell Death; Cells, C

2005