losartan has been researched along with Atrioventricular Nodal Re-Entrant Tachycardia in 6 studies
Losartan: An antagonist of ANGIOTENSIN TYPE 1 RECEPTOR with antihypertensive activity due to the reduced pressor effect of ANGIOTENSIN II.
losartan : A biphenylyltetrazole where a 1,1'-biphenyl group is attached at the 5-position and has an additional trisubstituted imidazol-1-ylmethyl group at the 4'-position
| Excerpt | Relevance | Reference |
|---|---|---|
| "Rats harboring the human renin and angiotensinogen genes (dTGR) feature angiotensin (ANG) II/hypertension-induced cardiac damage and die suddenly between wk 7 and 8." | 3.74 | Angiotensin II-induced sudden arrhythmic death and electrical remodeling. ( Dechend, R; Dietz, R; Fiebeler, A; Fischer, R; Gapelyuk, A; Gratze, P; Gruner, A; Gruner, K; Luft, FC; Muller, DN; Qadri, F; Schirdewan, A; Shagdarsuren, E; Wellner, M, 2007) |
| "Ischemic focal ventricular tachycardia (VT) occurs in animals and humans." | 1.35 | Angiotensin II effects on ischemic focal ventricular tachycardia are predominantly mediated through myocardial AT(2) receptor. ( Chaudhary, AK; Ely, D; Gopinathannair, R; Martins, JB; Xing, D; Zheng, W, 2009) |
| " In dose-finding experiments in non-hypertrophied isolated perfused hearts, we performed dose-response curves of losartan and enalaprilat studying monophasic action potential duration at 90% repolarisation (MAPD(90%)) and ventricular fibrillation (VF) threshold." | 1.32 | Losartan but not enalaprilat acutely reduces reperfusion ventricular tachyarrhythmias in hypertrophied rat hearts after low-flow ischaemia. ( Beier, K; Bellahcene, M; Buser, PT; Butz, S; Driamov, S; Remondino, A; Zaugg, CE; Ziegler, A, 2004) |
| "The incidence of ventricular tachyarrhythmias during reperfusion was lower in the losartan group than in the control group (4/15 vs 6/15)." | 1.30 | Effects of an angiotensin II antagonist on reperfusion arrhythmias in dogs. ( Annoura, M; Arakawa, K; Handa, K; Hiroki, T; Kumagai, K; Matsuo, K; Nakashima, Y; Yamanouchi, Y, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 5 (83.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gopinathannair, R | 1 |
| Chaudhary, AK | 1 |
| Xing, D | 1 |
| Ely, D | 1 |
| Zheng, W | 1 |
| Martins, JB | 1 |
| Butz, S | 1 |
| Driamov, S | 1 |
| Remondino, A | 1 |
| Bellahcene, M | 1 |
| Beier, K | 1 |
| Ziegler, A | 1 |
| Buser, PT | 1 |
| Zaugg, CE | 1 |
| Gao, L | 1 |
| Wang, W | 1 |
| Li, YL | 1 |
| Schultz, HD | 1 |
| Liu, D | 1 |
| Cornish, KG | 1 |
| Zucker, IH | 1 |
| Pourdjabbar, A | 1 |
| Parker, TG | 1 |
| Nguyen, QT | 1 |
| Desjardins, JF | 1 |
| Lapointe, N | 1 |
| Tsoporis, JN | 1 |
| Rouleau, JL | 1 |
| Fischer, R | 1 |
| Dechend, R | 1 |
| Gapelyuk, A | 1 |
| Shagdarsuren, E | 1 |
| Gruner, K | 1 |
| Gruner, A | 1 |
| Gratze, P | 1 |
| Qadri, F | 1 |
| Wellner, M | 1 |
| Fiebeler, A | 1 |
| Dietz, R | 1 |
| Luft, FC | 1 |
| Muller, DN | 1 |
| Schirdewan, A | 1 |
| Matsuo, K | 1 |
| Kumagai, K | 1 |
| Annoura, M | 1 |
| Yamanouchi, Y | 1 |
| Handa, K | 1 |
| Nakashima, Y | 1 |
| Hiroki, T | 1 |
| Arakawa, K | 1 |
6 other studies available for losartan and Atrioventricular Nodal Re-Entrant Tachycardia
| Article | Year |
|---|---|
Angiotensin II effects on ischemic focal ventricular tachycardia are predominantly mediated through myocardial AT(2) receptor.
Topics: Action Potentials; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Re | 2009 |
Losartan but not enalaprilat acutely reduces reperfusion ventricular tachyarrhythmias in hypertrophied rat hearts after low-flow ischaemia.
Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Dose-Response Relationship, Drug; Enalaprilat; H | 2004 |
Superoxide mediates sympathoexcitation in heart failure: roles of angiotensin II and NAD(P)H oxidase.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Blood Pressure; Ditiocarb; Heart F | 2004 |
Effects of pre-, peri-, and postmyocardial infarction treatment with losartan in rats: effect of dose on survival, ventricular arrhythmias, function, and remodeling.
Topics: Actins; Angiotensin II Type 1 Receptor Blockers; Animals; Atrial Natriuretic Factor; Blood Pressure; | 2005 |
Angiotensin II-induced sudden arrhythmic death and electrical remodeling.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensinogen; Animals; Animals, Genetica | 2007 |
Effects of an angiotensin II antagonist on reperfusion arrhythmias in dogs.
Topics: Aldosterone; Angiotensin Receptor Antagonists; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac | 1997 |