losartan has been researched along with Astrocytoma, Grade IV in 3 studies
Losartan: An antagonist of ANGIOTENSIN TYPE 1 RECEPTOR with antihypertensive activity due to the reduced pressor effect of ANGIOTENSIN II.
losartan : A biphenylyltetrazole where a 1,1'-biphenyl group is attached at the 5-position and has an additional trisubstituted imidazol-1-ylmethyl group at the 4'-position
| Excerpt | Relevance | Reference |
|---|---|---|
| " The primary objective was to investigate the steroid dosage required to control brain oedema on the last day of RT in each arm." | 2.90 | Angiotensin II receptor blockers, steroids and radiotherapy in glioblastoma-a randomised multicentre trial (ASTER trial). An ANOCEF study. ( Carpentier, AF; Charissoux, M; Chinot, O; Cuzzubbo, S; Ducray, F; Hoang-Xuan, K; Le Rhun, E; Levy-Piedbois, C; Mandonnet, E; Portal, JJ; Psimaras, D; Quillien, V; Ricard, D; Sejalon, F; Thomas, L; Tibi, A; Ursu, R; Vicaut, E, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 2 (66.67) | 2.80 |
| Authors | Studies |
|---|---|
| Datta, M | 1 |
| Chatterjee, S | 1 |
| Perez, EM | 1 |
| Gritsch, S | 1 |
| Roberge, S | 1 |
| Duquette, M | 1 |
| Chen, IX | 1 |
| Naxerova, K | 1 |
| Kumar, AS | 1 |
| Ghosh, M | 1 |
| Emblem, KE | 1 |
| Ng, MR | 1 |
| Ho, WW | 1 |
| Kumar, P | 1 |
| Krishnan, S | 1 |
| Dong, X | 1 |
| Speranza, MC | 1 |
| Neagu, MR | 1 |
| Iorgulescu, JB | 1 |
| Huang, RY | 1 |
| Youssef, G | 1 |
| Reardon, DA | 1 |
| Sharpe, AH | 1 |
| Freeman, GJ | 1 |
| Suvà, ML | 1 |
| Xu, L | 1 |
| Jain, RK | 1 |
| Tsiailanis, AD | 1 |
| Renziehausen, A | 1 |
| Kiriakidi, S | 1 |
| Vrettos, EI | 1 |
| Markopoulos, GS | 1 |
| Sayyad, N | 1 |
| Hirmiz, B | 1 |
| Aguilar, MI | 1 |
| Del Borgo, MP | 1 |
| Kolettas, E | 1 |
| Widdop, RE | 1 |
| Mavromoustakos, T | 1 |
| Crook, T | 1 |
| Syed, N | 1 |
| Tzakos, AG | 1 |
| Ursu, R | 1 |
| Thomas, L | 1 |
| Psimaras, D | 1 |
| Chinot, O | 1 |
| Le Rhun, E | 1 |
| Ricard, D | 1 |
| Charissoux, M | 1 |
| Cuzzubbo, S | 1 |
| Sejalon, F | 1 |
| Quillien, V | 1 |
| Hoang-Xuan, K | 1 |
| Ducray, F | 1 |
| Portal, JJ | 1 |
| Tibi, A | 1 |
| Mandonnet, E | 1 |
| Levy-Piedbois, C | 1 |
| Vicaut, E | 1 |
| Carpentier, AF | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Angiotensin II Receptor Blockers, Steroids and Radiotherapy in Glioblastoma- A Randomized Multicenter Trial[NCT01805453] | Phase 3 | 80 participants (Actual) | Interventional | 2013-03-29 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for losartan and Astrocytoma, Grade IV
| Article | Year |
|---|---|
Angiotensin II receptor blockers, steroids and radiotherapy in glioblastoma-a randomised multicentre trial (ASTER trial). An ANOCEF study.
Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Anti-Inflammatory Agents; Brain Neoplasms; Chemoradio | 2019 |
2 other studies available for losartan and Astrocytoma, Grade IV
| Article | Year |
|---|---|
Losartan controls immune checkpoint blocker-induced edema and improves survival in glioblastoma mouse models.
Topics: Animals; CD8-Positive T-Lymphocytes; Edema; Glioblastoma; Immune Checkpoint Inhibitors; Losartan; Mi | 2023 |
Enhancement of glioblastoma multiforme therapy through a novel Quercetin-Losartan hybrid.
Topics: Brain Neoplasms; Cell Line, Tumor; Glioblastoma; Humans; Losartan; Quercetin; Temozolomide | 2020 |