losartan has been researched along with Apnea, Obstructive Sleep in 7 studies
Losartan: An antagonist of ANGIOTENSIN TYPE 1 RECEPTOR with antihypertensive activity due to the reduced pressor effect of ANGIOTENSIN II.
losartan : A biphenylyltetrazole where a 1,1'-biphenyl group is attached at the 5-position and has an additional trisubstituted imidazol-1-ylmethyl group at the 4'-position
| Excerpt | Relevance | Reference |
|---|---|---|
| "To address the cardiovascular mechanisms involved in response to an angiotensin II receptor antagonist, losartan, and continuous positive airway pressure (CPAP) as add-on treatment for hypertension and OSA." | 9.22 | Neuroendocrine and Inflammatory Responses to Losartan and Continuous Positive Airway Pressure in Patients with Hypertension and Obstructive Sleep Apnea. A Randomized Controlled Trial. ( Lindberg, C; Manhem, K; Peker, Y; Rosengren, A; Thunström, E; Yucel-Lindberg, T, 2016) |
| "Obstructive sleep apnea is characterized by chronic intermittent hypoxia (CIH), which is a risk factor for renal peritubular capillary (PTC) loss, and angiotensin II receptor blockers can alleviate PTC loss." | 7.96 | Losartan protects against intermittent hypoxia-induced peritubular capillary loss by modulating the renal renin-angiotensin system and angiogenesis factors. ( Chu, Y; Jiang, Z; Wu, J; Yu, Q, 2020) |
| "Ninety-one patients with untreated hypertension underwent a home sleep study (55 were found to have OSA; 36 were not)." | 6.82 | Blood Pressure Response to Losartan and Continuous Positive Airway Pressure in Hypertension and Obstructive Sleep Apnea. ( Manhem, K; Peker, Y; Rosengren, A; Thunström, E, 2016) |
| "To address the cardiovascular mechanisms involved in response to an angiotensin II receptor antagonist, losartan, and continuous positive airway pressure (CPAP) as add-on treatment for hypertension and OSA." | 5.22 | Neuroendocrine and Inflammatory Responses to Losartan and Continuous Positive Airway Pressure in Patients with Hypertension and Obstructive Sleep Apnea. A Randomized Controlled Trial. ( Lindberg, C; Manhem, K; Peker, Y; Rosengren, A; Thunström, E; Yucel-Lindberg, T, 2016) |
| "We compared the effects of atenolol (50 mg), amlodipine (5 mg), enalapril (20 mg), hydrochlorothiazide (25 mg), and losartan (50 mg) given in once-daily oral doses on office and ambulatory blood pressures (BPs) in patients with hypertension and obstructive sleep apnea (OSA)." | 5.09 | Comparison of atenolol, amlodipine, enalapril, hydrochlorothiazide, and losartan for antihypertensive treatment in patients with obstructive sleep apnea. ( Grote, L; Hedner, J; Kraiczi, H; Peker, Y, 2000) |
| "Obstructive sleep apnea is characterized by chronic intermittent hypoxia (CIH), which is a risk factor for renal peritubular capillary (PTC) loss, and angiotensin II receptor blockers can alleviate PTC loss." | 3.96 | Losartan protects against intermittent hypoxia-induced peritubular capillary loss by modulating the renal renin-angiotensin system and angiogenesis factors. ( Chu, Y; Jiang, Z; Wu, J; Yu, Q, 2020) |
| "Ninety-one patients with untreated hypertension underwent a home sleep study (55 were found to have OSA; 36 were not)." | 2.82 | Blood Pressure Response to Losartan and Continuous Positive Airway Pressure in Hypertension and Obstructive Sleep Apnea. ( Manhem, K; Peker, Y; Rosengren, A; Thunström, E, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (28.57) | 29.6817 |
| 2010's | 4 (57.14) | 24.3611 |
| 2020's | 1 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Wu, J | 1 |
| Chu, Y | 1 |
| Jiang, Z | 1 |
| Yu, Q | 1 |
| Jenner, R | 1 |
| Fatureto-Borges, F | 1 |
| Costa-Hong, V | 1 |
| Lopes, HF | 1 |
| Teixeira, SH | 1 |
| Marum, E | 1 |
| Giorgi, DAM | 1 |
| Consolim-Colombo, FM | 1 |
| Bortolotto, LA | 1 |
| Lorenzi-Filho, G | 1 |
| Krieger, EM | 1 |
| Drager, LF | 1 |
| Thunström, E | 2 |
| Manhem, K | 2 |
| Rosengren, A | 2 |
| Peker, Y | 3 |
| White, DP | 1 |
| Yucel-Lindberg, T | 1 |
| Lindberg, C | 1 |
| Zelveian, PA | 1 |
| Oshchepkova, EV | 1 |
| Buniatian, MS | 1 |
| Rogoza, AN | 1 |
| Kraiczi, H | 1 |
| Hedner, J | 1 |
| Grote, L | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Phase 4 Study of Losartan in Hypertensive Men and Women With Obstructive Sleep Apnea Before and After Continuous Positive Airway Pressure (CPAP) Treatment[NCT00701428] | Phase 4 | 90 participants (Actual) | Interventional | 2008-06-30 | Completed | ||
| Comparative Study of Effect of Valsartan 160mg Treatment Versus Continuous Positive Airway Pressure on Arterial Blood Pressure in Patients Who Have an Obstructive Sleep Apnea Syndrome and a Weak or Moderate Hypertension.[NCT00409487] | Phase 4 | 60 participants (Anticipated) | Interventional | 2006-12-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 trials available for losartan and Apnea, Obstructive Sleep
| Article | Year |
|---|---|
Blood Pressure Response to Losartan and Continuous Positive Airway Pressure in Hypertension and Obstructive Sleep Apnea.
Topics: Angiotensin Receptor Antagonists; Blood Pressure; Case-Control Studies; Continuous Positive Airway P | 2016 |
Neuroendocrine and Inflammatory Responses to Losartan and Continuous Positive Airway Pressure in Patients with Hypertension and Obstructive Sleep Apnea. A Randomized Controlled Trial.
Topics: Aldosterone; Antihypertensive Agents; Blood Pressure; Case-Control Studies; Continuous Positive Airw | 2016 |
Comparison of atenolol, amlodipine, enalapril, hydrochlorothiazide, and losartan for antihypertensive treatment in patients with obstructive sleep apnea.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Anti | 2000 |
4 other studies available for losartan and Apnea, Obstructive Sleep
| Article | Year |
|---|---|
Losartan protects against intermittent hypoxia-induced peritubular capillary loss by modulating the renal renin-angiotensin system and angiogenesis factors.
Topics: Angiogenesis Inducing Agents; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Body | 2020 |
Association of obstructive sleep apnea with arterial stiffness and nondipping blood pressure in patients with hypertension.
Topics: Adult; Aged; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Bloo | 2017 |
Is Continuous Positive Airway Pressure an Effective and Practical Antihypertensive Agent?
Topics: Angiotensin Receptor Antagonists; Blood Pressure; Continuous Positive Airway Pressure; Female; Human | 2016 |
[Characteristics of hypotensive effect in patients with arterial hypertension and desaturation signs of obstructive sleep apnea syndrome during sleep].
Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Blood Gas Monitoring, Transcutaneous; Blood Pressu | 2004 |