losartan has been researched along with Aortic Stenosis in 7 studies
Losartan: An antagonist of ANGIOTENSIN TYPE 1 RECEPTOR with antihypertensive activity due to the reduced pressor effect of ANGIOTENSIN II.
losartan : A biphenylyltetrazole where a 1,1'-biphenyl group is attached at the 5-position and has an additional trisubstituted imidazol-1-ylmethyl group at the 4'-position
| Excerpt | Relevance | Reference |
|---|---|---|
| "Wistar rats were divided into the following 4 groups: 1) C--control (n=13); 2) AoS--aortic stenosis (n=11); 3) LIS--AoS treated with lisinopril, 20 mg/kg/day (n=11); and 4) LOS--AoS treated with losartan, 40 mg/kg/day (n=9)." | 3.73 | [Blockade of renin-angiotensin system attenuates cardiac remodeling in rats undergoing aortic stenosis]. ( Aragon, FF; Cicogna, AC; Cordaro, FR; Gonçalves, G; Okoshi, K; Okoshi, MP; Padovani, CR; Ribeiro, HB; Zornoff, LA, 2005) |
| "Our data do not support a role for the AT1 receptor in the progression of atherosclerosis in this model, since blockade with losartan did not alter plaque distribution." | 3.73 | Blood pressure is the major driving force for plaque formation in aortic-constricted ApoE-/- mice. ( Bergström, G; Gan, LM; Johansson, ME; Skøtt, O; Wickman, A, 2006) |
| " We investigated the changes of ceramide lipid components in hypertrophied immature rabbit hearts after chronic administration of the AT1 -receptor blocker, losartan." | 1.39 | Modulation of C16:0-ceramide in hypertrophied immature hearts by losartan. ( Itoi, T; Oka, T; Terada, N, 2013) |
| "Cardiac hypertrophy was induced by abdominal aortic stenosis (AAS) in Sprague-Dawley rats." | 1.33 | Role of myofibrillogenesis regulator-1 in myocardial hypertrophy. ( Li, T; Liu, X; Sun, S; Wang, Y; Xu, F, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (57.14) | 29.6817 |
| 2010's | 2 (28.57) | 24.3611 |
| 2020's | 1 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Flyer, JN | 1 |
| Sleeper, LA | 1 |
| Colan, SD | 1 |
| Singh, MN | 1 |
| Lacro, RV | 1 |
| Lüscher, TF | 1 |
| Itoi, T | 1 |
| Oka, T | 1 |
| Terada, N | 1 |
| Hiyoshi, H | 1 |
| Yayama, K | 1 |
| Takano, M | 1 |
| Okamoto, H | 1 |
| Gonçalves, G | 1 |
| Zornoff, LA | 1 |
| Ribeiro, HB | 1 |
| Okoshi, MP | 1 |
| Cordaro, FR | 1 |
| Okoshi, K | 1 |
| Padovani, CR | 1 |
| Aragon, FF | 1 |
| Cicogna, AC | 1 |
| Liu, X | 1 |
| Li, T | 1 |
| Sun, S | 1 |
| Xu, F | 1 |
| Wang, Y | 1 |
| Johansson, ME | 1 |
| Wickman, A | 1 |
| Skøtt, O | 1 |
| Gan, LM | 1 |
| Bergström, G | 1 |
7 other studies available for losartan and Aortic Stenosis
| Article | Year |
|---|---|
Effect of Losartan or Atenolol on Children and Young Adults With Bicuspid Aortic Valve and Dilated Aorta.
Topics: Adolescent; Adrenergic beta-1 Receptor Antagonists; Adult; Angiotensin II Type 1 Receptor Blockers; | 2021 |
Atherosclerosis, neoatherosclerosis, and vascular disease.
Topics: Angiotensin II Type 1 Receptor Blockers; Aortic Diseases; Aortic Valve Stenosis; Cardiovascular Dise | 2015 |
Modulation of C16:0-ceramide in hypertrophied immature hearts by losartan.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Animals, Newborn; Aortic Valve Stenosis; Cardiomeg | 2013 |
Stimulation of cyclic GMP production via AT2 and B2 receptors in the pressure-overloaded aorta after banding.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; An | 2004 |
[Blockade of renin-angiotensin system attenuates cardiac remodeling in rats undergoing aortic stenosis].
Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Aortic V | 2005 |
Role of myofibrillogenesis regulator-1 in myocardial hypertrophy.
Topics: Amino Acid Sequence; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Animals, Newb | 2006 |
Blood pressure is the major driving force for plaque formation in aortic-constricted ApoE-/- mice.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Aortic Valve Stenosis; Atherosclerosis; Blood Pres | 2006 |