losartan has been researched along with Aortic Aneurysm, Ruptured in 6 studies
Losartan: An antagonist of ANGIOTENSIN TYPE 1 RECEPTOR with antihypertensive activity due to the reduced pressor effect of ANGIOTENSIN II.
losartan : A biphenylyltetrazole where a 1,1'-biphenyl group is attached at the 5-position and has an additional trisubstituted imidazol-1-ylmethyl group at the 4'-position
| Excerpt | Relevance | Reference |
|---|---|---|
| "Angiotensin II (AngII) mediates progression of aortic aneurysm, but the relative contribution of its type 1 (AT1) and type 2 (AT2) receptors remains unknown." | 7.77 | Angiotensin II type 2 receptor signaling attenuates aortic aneurysm in mice through ERK antagonism. ( Aziz, H; Bedja, D; Chen, Y; Dietz, HC; Doyle, JJ; Habashi, JP; Holm, TM; Judge, DP; Modiri, AN; Schoenhoff, F, 2011) |
| "Angiotensin II (AngII) mediates progression of aortic aneurysm, but the relative contribution of its type 1 (AT1) and type 2 (AT2) receptors remains unknown." | 3.77 | Angiotensin II type 2 receptor signaling attenuates aortic aneurysm in mice through ERK antagonism. ( Aziz, H; Bedja, D; Chen, Y; Dietz, HC; Doyle, JJ; Habashi, JP; Holm, TM; Judge, DP; Modiri, AN; Schoenhoff, F, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (50.00) | 24.3611 |
| 2020's | 2 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Sawada, H | 1 |
| Ohno-Urabe, S | 1 |
| Ye, D | 1 |
| Franklin, MK | 1 |
| Moorleghen, JJ | 1 |
| Howatt, DA | 1 |
| Mullick, AE | 1 |
| Daugherty, A | 2 |
| Lu, HS | 1 |
| Dubacher, N | 1 |
| Münger, J | 1 |
| Gorosabel, MC | 1 |
| Crabb, J | 1 |
| Ksiazek, AA | 1 |
| Caspar, SM | 1 |
| Bakker, ENTP | 1 |
| van Bavel, E | 1 |
| Ziegler, U | 1 |
| Carrel, T | 1 |
| Steinmann, B | 1 |
| Zeisberger, S | 1 |
| Meienberg, J | 1 |
| Matyas, G | 1 |
| Liu, S | 1 |
| Xie, Z | 1 |
| Cassis, LA | 1 |
| Pearson, KJ | 1 |
| Gong, MC | 1 |
| Guo, Z | 1 |
| Cook, JR | 1 |
| Clayton, NP | 1 |
| Carta, L | 1 |
| Galatioto, J | 1 |
| Chiu, E | 1 |
| Smaldone, S | 1 |
| Nelson, CA | 1 |
| Cheng, SH | 1 |
| Wentworth, BM | 1 |
| Ramirez, F | 1 |
| Habashi, JP | 1 |
| Doyle, JJ | 1 |
| Holm, TM | 1 |
| Aziz, H | 1 |
| Schoenhoff, F | 1 |
| Bedja, D | 1 |
| Chen, Y | 1 |
| Modiri, AN | 1 |
| Judge, DP | 1 |
| Dietz, HC | 1 |
| Huang, W | 1 |
| Alhenc Gelas, F | 1 |
| Osborne-Pellegrin, MJ | 1 |
6 other studies available for losartan and Aortic Aneurysm, Ruptured
| Article | Year |
|---|---|
Inhibition of the Renin-Angiotensin System Fails to Suppress β-Aminopropionitrile-Induced Thoracic Aortopathy in Mice-Brief Report.
Topics: Aminopropionitrile; Angiotensin II; Angiotensinogen; Animals; Aortic Aneurysm, Thoracic; Aortic Rupt | 2022 |
Celiprolol but not losartan improves the biomechanical integrity of the aorta in a mouse model of vascular Ehlers-Danlos syndrome.
Topics: Adrenergic beta-1 Receptor Antagonists; Angiotensin II Type 1 Receptor Blockers; Animals; Aorta, Tho | 2020 |
Mineralocorticoid receptor agonists induce mouse aortic aneurysm formation and rupture in the presence of high salt.
Topics: Aldosterone; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Anim | 2013 |
Dimorphic effects of transforming growth factor-β signaling during aortic aneurysm progression in mice suggest a combinatorial therapy for Marfan syndrome.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Antibodies, Neutralizing; Aorta, Thoracic; Aortic | 2015 |
Angiotensin II type 2 receptor signaling attenuates aortic aneurysm in mice through ERK antagonism.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; A | 2011 |
Protection of the arterial internal elastic lamina by inhibition of the renin-angiotensin system in the rat.
Topics: Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Aorta, Abdominal; Ao | 1998 |