losartan has been researched along with Angor Pectoris in 8 studies
Losartan: An antagonist of ANGIOTENSIN TYPE 1 RECEPTOR with antihypertensive activity due to the reduced pressor effect of ANGIOTENSIN II.
losartan : A biphenylyltetrazole where a 1,1'-biphenyl group is attached at the 5-position and has an additional trisubstituted imidazol-1-ylmethyl group at the 4'-position
| Excerpt | Relevance | Reference |
|---|---|---|
| " These posthoc analyses from the Losartan Intervention For Endpoint reduction in hypertension (LIFE) study evaluated losartan- versus atenolol-based therapy on the primary composite end point of cardiovascular death, stroke, and myocardial infarction and other end points in 4963 women." | 9.13 | Effects of losartan in women with hypertension and left ventricular hypertrophy: results from the Losartan Intervention for Endpoint Reduction in Hypertension Study. ( Dahlöf, B; Devereux, RB; Franco, V; Gerdts, E; Hille, DA; Kjeldsen, SE; Lyle, PA; Manhem, K; Okin, PM; Oparil, S; Os, I, 2008) |
| "We sought to demonstrate non-angiotensin converting enzyme (ACE) dependent angiotensin II (AII) generating pathways in resistance arteries from patients with chronic heart failure (CHF)." | 7.71 | Angiotensin converting enzyme (ACE) and non-ACE dependent angiotensin II generation in resistance arteries from patients with heart failure and coronary heart disease. ( Connell, JM; Hillier, C; McDonald, JE; McMurray, JJ; Padmanabhan, N; Petrie, MC, 2001) |
| " These posthoc analyses from the Losartan Intervention For Endpoint reduction in hypertension (LIFE) study evaluated losartan- versus atenolol-based therapy on the primary composite end point of cardiovascular death, stroke, and myocardial infarction and other end points in 4963 women." | 5.13 | Effects of losartan in women with hypertension and left ventricular hypertrophy: results from the Losartan Intervention for Endpoint Reduction in Hypertension Study. ( Dahlöf, B; Devereux, RB; Franco, V; Gerdts, E; Hille, DA; Kjeldsen, SE; Lyle, PA; Manhem, K; Okin, PM; Oparil, S; Os, I, 2008) |
| "In 9193 hypertensive patients included in the Losartan Intervention For Endpoint reduction in hypertension (LIFE) study, we measured urine albumin/creatinine ratio (UACR), LV hypertrophy by electrocardiography, serum high-density lipoprotein (HDL) cholesterol, and blood pressure after 2 weeks of placebo treatment and yearly during 5 years of anti-hypertensive treatment with either an atenolol- or a losartan-based regimen." | 3.76 | Lack of regression of left ventricular hypertrophy is associated with higher incidence of revascularization in hypertension: The LIFE Study. ( Dahlöf, B; Devereux, RB; Kjeldsen, SE; Okin, PM; Olsen, MH; Søraas, CL; Tønnessen, T; Wachtell, K, 2010) |
| "We sought to demonstrate non-angiotensin converting enzyme (ACE) dependent angiotensin II (AII) generating pathways in resistance arteries from patients with chronic heart failure (CHF)." | 3.71 | Angiotensin converting enzyme (ACE) and non-ACE dependent angiotensin II generation in resistance arteries from patients with heart failure and coronary heart disease. ( Connell, JM; Hillier, C; McDonald, JE; McMurray, JJ; Padmanabhan, N; Petrie, MC, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (12.50) | 18.2507 |
| 2000's | 6 (75.00) | 29.6817 |
| 2010's | 1 (12.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Søraas, CL | 1 |
| Wachtell, K | 1 |
| Okin, PM | 2 |
| Dahlöf, B | 2 |
| Devereux, RB | 2 |
| Tønnessen, T | 1 |
| Kjeldsen, SE | 2 |
| Olsen, MH | 1 |
| Trevelyan, J | 1 |
| Brull, DJ | 1 |
| Needham, EW | 1 |
| Montgomery, HE | 1 |
| Morris, A | 1 |
| Mattu, RK | 1 |
| Edwards, RJ | 1 |
| Redwood, SR | 1 |
| Lambiase, PD | 1 |
| Marber, MS | 1 |
| Longobardi, G | 1 |
| Ferrara, N | 1 |
| Leosco, D | 1 |
| Abete, P | 1 |
| Furgi, G | 1 |
| Cacciatore, F | 1 |
| Corbi, G | 1 |
| Pescatore, R | 1 |
| Rengo, F | 1 |
| Os, I | 1 |
| Franco, V | 1 |
| Manhem, K | 1 |
| Gerdts, E | 1 |
| Hille, DA | 1 |
| Lyle, PA | 1 |
| Oparil, S | 1 |
| Ahmad, S | 1 |
| Vizir, VA | 1 |
| Berezin, AE | 1 |
| Petrie, MC | 1 |
| Padmanabhan, N | 1 |
| McDonald, JE | 1 |
| Hillier, C | 1 |
| Connell, JM | 1 |
| McMurray, JJ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Triple-Blind, Parallel Study to Investigate the Effect of Losartan Versus Atenolol on the Reduction of Morbidity and Mortality in Hypertensive Patients With Left Ventricular Hypertrophy[NCT00338260] | Phase 3 | 496 participants (Actual) | Interventional | 1995-06-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 trials available for losartan and Angor Pectoris
| Article | Year |
|---|---|
Effect of enalapril and losartan on cytokines in patients with stable angina pectoris awaiting coronary artery bypass grafting and their interaction with polymorphisms in the interleukin-6 gene.
Topics: Aged; Angina Pectoris; Antihypertensive Agents; Coronary Artery Bypass; Cytokines; Enalapril; Genoty | 2004 |
The effect of an angiotensin-converting enzyme inhibitor and a K+(ATP) channel opener on warm up angina.
Topics: Adaptation, Physiological; Angina Pectoris; Angiotensin Receptor Antagonists; Angiotensin-Converting | 2005 |
Angiotensin II-receptor antagonist losartan does not prevent nitroglycerin tolerance in patients with coronary artery disease.
Topics: Administration, Cutaneous; Angina Pectoris; Angiotensin II Type 1 Receptor Blockers; Blood Pressure; | 2004 |
Effects of losartan in women with hypertension and left ventricular hypertrophy: results from the Losartan Intervention for Endpoint Reduction in Hypertension Study.
Topics: Aged; Aged, 80 and over; Angina Pectoris; Antihypertensive Agents; Atenolol; Blood Pressure; Female; | 2008 |
[Prospects of endothelial dysfunction reversion in patients with congestive heart failure].
Topics: Angina Pectoris; Angiotensin-Converting Enzyme Inhibitors; Blood Flow Velocity; Brachial Artery; Ena | 2000 |
3 other studies available for losartan and Angor Pectoris
| Article | Year |
|---|---|
Lack of regression of left ventricular hypertrophy is associated with higher incidence of revascularization in hypertension: The LIFE Study.
Topics: Aged; Albuminuria; Angina Pectoris; Antihypertensive Agents; Atenolol; Blood Pressure; Cholesterol, | 2010 |
Losartan and angina pectoris.
Topics: Aged; Angina Pectoris; Antihypertensive Agents; Biphenyl Compounds; Humans; Hypertension; Imidazoles | 1995 |
Angiotensin converting enzyme (ACE) and non-ACE dependent angiotensin II generation in resistance arteries from patients with heart failure and coronary heart disease.
Topics: Acetylcholine; Aged; Angina Pectoris; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme I | 2001 |