losartan has been researched along with Angioedema in 28 studies
Losartan: An antagonist of ANGIOTENSIN TYPE 1 RECEPTOR with antihypertensive activity due to the reduced pressor effect of ANGIOTENSIN II.
losartan : A biphenylyltetrazole where a 1,1'-biphenyl group is attached at the 5-position and has an additional trisubstituted imidazol-1-ylmethyl group at the 4'-position
Angioedema: Swelling involving the deep DERMIS, subcutaneous, or submucosal tissues, representing localized EDEMA. Angioedema often occurs in the face, lips, tongue, and larynx.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We report a rare case of life-threatening anaphylaxis after losartan use." | 8.31 | Losartan-Induced Angioedema with Acute Hypoxemic Respiratory Failure (Anaphylaxis): A Case Report. ( Kagzi, A; Kagzi, Y; Money, DB; Oxner, AZ, 2023) |
| "To describe a case of angioedema associated with increasing the dose of HMG-CoA reductase inhibitor (atorvastatin) from 20 to 40 mg daily in a patient previously stable on angiotensin II receptor blocker (losartan) and calcium channel blocker (amlodipine) as antihypertensive agents." | 8.12 | Dose-dependent atorvastatin associated with angioedema. ( Al-Mohammadi, OS; Al-Qaaneh, AM; Mustafa, SM; Obaid, WT; Rabaan, AA, 2022) |
| "A case of anaphylaxis and angioedema induced by angiotensin II receptor blocker (ARB), losartan is reported." | 7.76 | Losartan associated anaphylaxis and angioneurotic oedema. ( Kazim, SF; Shahid, M, 2010) |
| "We reviewed the 13 case reports of angioedema associated with the use of losartan reported to Lareb (Netherlands Pharmacovigilance Foundation, Den Bosch) and to the Drug Safety Unit of the Inspectorate for Health Care, Ryswyh, in the Netherlands since the introduction of losartan in 1995 until May 1997." | 7.70 | Angioneurotic edema attributed to the use of losartan. ( Feenstra, J; Kwee-Zuiderwijk, WJ; van Rijnsoever, EW, 1998) |
| "To report a case of angioedema associated with losartan administration." | 7.70 | Losartan-induced angioedema. ( Rivera, JO, 1999) |
| "To report a case of angioedema associated with the angiotensin II receptor antagonist losartan." | 7.70 | Angioedema due to losartan. ( Cha, YJ; Pearson, VE, 1999) |
| "Angioedema has not been associated with losartan therapy in hemodialysis patients, as it has been with angiotensin converting enzyme (ACE) inhibitors." | 7.69 | Angioedema associated with angiotensin II receptor antagonist losartan. ( Sharma, PK; Yium, JJ, 1997) |
| " Propensity scores were generated, and differences in BP and adverse events (angioedema, acute kidney injury, hyperkalemia) between BID/QDay groups were analyzed within dosing cohorts using inverse propensity of treatment-weighted regression models." | 5.56 | Twice-daily versus once-daily lisinopril and losartan for hypertension: Real-world effectiveness and safety. ( Botts, SR; Delate, T; Derington, CG; Kao, DP; King, JB; Kroehl, M; Trinkley, KE, 2020) |
| "Angioedema is a very rare side effect associated with ACE inhibitors (ACEI) and even rarer so with ARBs." | 5.36 | A case of losartan induced angioedema. ( Nair, C, 2010) |
| "Angioedema and cough are known side effects of angiotensin-converting enzyme (ACE) inhibitors." | 5.31 | Angiotensin II receptor blocker-associated angioedema: on the heels of ACE inhibitor angioedema. ( Abdi, R; Dong, VM; Lee, CJ; Ntoso, KA, 2002) |
| " Key search terms included angioneurotic edema, angiotensin-converting enzyme inhibitors, receptors-angiotensin, and losartan." | 4.80 | Angiotensin II receptor blockers in patients with ACE inhibitor-induced angioedema. ( Tschampel, MM; Visconti, JA; Warner, KK, 2000) |
| " We report a rare case of life-threatening anaphylaxis after losartan use." | 4.31 | Losartan-Induced Angioedema with Acute Hypoxemic Respiratory Failure (Anaphylaxis): A Case Report. ( Kagzi, A; Kagzi, Y; Money, DB; Oxner, AZ, 2023) |
| "To describe a case of angioedema associated with increasing the dose of HMG-CoA reductase inhibitor (atorvastatin) from 20 to 40 mg daily in a patient previously stable on angiotensin II receptor blocker (losartan) and calcium channel blocker (amlodipine) as antihypertensive agents." | 4.12 | Dose-dependent atorvastatin associated with angioedema. ( Al-Mohammadi, OS; Al-Qaaneh, AM; Mustafa, SM; Obaid, WT; Rabaan, AA, 2022) |
| "A case of anaphylaxis and angioedema induced by angiotensin II receptor blocker (ARB), losartan is reported." | 3.76 | Losartan associated anaphylaxis and angioneurotic oedema. ( Kazim, SF; Shahid, M, 2010) |
| "Three patients taking the AT2 blocker losartan presented with mucosal swelling in the head and neck clinically consistent with angioedema." | 3.71 | Angioedema associated with angiotensin II receptor antagonists: challenging our knowledge of angioedema and its etiology. ( Chiu, AG; Deeb, ZE; Krowiak, EJ, 2001) |
| "We reviewed the 13 case reports of angioedema associated with the use of losartan reported to Lareb (Netherlands Pharmacovigilance Foundation, Den Bosch) and to the Drug Safety Unit of the Inspectorate for Health Care, Ryswyh, in the Netherlands since the introduction of losartan in 1995 until May 1997." | 3.70 | Angioneurotic edema attributed to the use of losartan. ( Feenstra, J; Kwee-Zuiderwijk, WJ; van Rijnsoever, EW, 1998) |
| "To report a case of angioedema associated with losartan administration." | 3.70 | Losartan-induced angioedema. ( Rivera, JO, 1999) |
| "To report a case of angioedema associated with the angiotensin II receptor antagonist losartan." | 3.70 | Angioedema due to losartan. ( Cha, YJ; Pearson, VE, 1999) |
| "Angioedema has not been associated with losartan therapy in hemodialysis patients, as it has been with angiotensin converting enzyme (ACE) inhibitors." | 3.69 | Angioedema associated with angiotensin II receptor antagonist losartan. ( Sharma, PK; Yium, JJ, 1997) |
| "Angioedema is an uncommon but potentially life-threatening adverse event associated with ACE inhibitor therapy which is believed to be due to potentiation of the vascular effects of bradykinin." | 2.41 | Can angiotensin receptor antagonists be used safely in patients with previous ACE inhibitor-induced angioedema? ( Howes, LG; Tran, D, 2002) |
| "Angioedema was not reported in the comparative trials described." | 2.40 | ACE inhibitor- versus angiotensin II blocker-induced cough and angioedema. ( Pylypchuk, GB, 1998) |
| " Propensity scores were generated, and differences in BP and adverse events (angioedema, acute kidney injury, hyperkalemia) between BID/QDay groups were analyzed within dosing cohorts using inverse propensity of treatment-weighted regression models." | 1.56 | Twice-daily versus once-daily lisinopril and losartan for hypertension: Real-world effectiveness and safety. ( Botts, SR; Delate, T; Derington, CG; Kao, DP; King, JB; Kroehl, M; Trinkley, KE, 2020) |
| "Angioedema is a very rare side effect associated with ACE inhibitors (ACEI) and even rarer so with ARBs." | 1.36 | A case of losartan induced angioedema. ( Nair, C, 2010) |
| "Angioedema and cough are known side effects of angiotensin-converting enzyme (ACE) inhibitors." | 1.31 | Angiotensin II receptor blocker-associated angioedema: on the heels of ACE inhibitor angioedema. ( Abdi, R; Dong, VM; Lee, CJ; Ntoso, KA, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 10 (35.71) | 18.2507 |
| 2000's | 7 (25.00) | 29.6817 |
| 2010's | 8 (28.57) | 24.3611 |
| 2020's | 3 (10.71) | 2.80 |
| Authors | Studies |
|---|---|
| Al-Qaaneh, AM | 2 |
| Obaid, WT | 1 |
| Al-Mohammadi, OS | 1 |
| Rabaan, AA | 1 |
| Mustafa, SM | 1 |
| Kagzi, Y | 1 |
| Money, DB | 1 |
| Oxner, AZ | 1 |
| Kagzi, A | 1 |
| Derington, CG | 1 |
| King, JB | 1 |
| Delate, T | 1 |
| Botts, SR | 1 |
| Kroehl, M | 1 |
| Kao, DP | 1 |
| Trinkley, KE | 1 |
| Sacco, KA | 1 |
| Mousa, OY | 1 |
| Wang, MH | 1 |
| Diestro, JDB | 1 |
| Sedano, LSP | 1 |
| Reyes, NGD | 1 |
| San Jose, MCZ | 1 |
| Venci, JV | 1 |
| Shamaskin, JA | 1 |
| Ferastraoaru, D | 1 |
| Rosenstreich, D | 1 |
| Jariwala, S | 1 |
| Thalanayar, MP | 1 |
| Fajt, ML | 1 |
| Birnie, KM | 1 |
| Ghobrial, II | 1 |
| Petrov, AA | 1 |
| Kazim, SF | 1 |
| Shahid, M | 1 |
| Orgaz-Molina, J | 1 |
| Soriano-Hernández, MI | 1 |
| Husein-Elahmed, H | 1 |
| Arias-Santiago, S | 1 |
| Nair, C | 1 |
| Abdi, R | 1 |
| Dong, VM | 1 |
| Lee, CJ | 1 |
| Ntoso, KA | 1 |
| MacLean, JA | 1 |
| Hannaway, PJ | 1 |
| Bork, K | 1 |
| Dewald, G | 1 |
| Acker, CG | 1 |
| Greenberg, A | 1 |
| Boxer, M | 1 |
| Gabb, GM | 1 |
| Sharma, PK | 1 |
| Yium, JJ | 1 |
| van Rijnsoever, EW | 1 |
| Kwee-Zuiderwijk, WJ | 1 |
| Feenstra, J | 1 |
| Pylypchuk, GB | 1 |
| Rupprecht, R | 1 |
| Vente, C | 1 |
| Gräfe, A | 1 |
| Fuchs, T | 1 |
| Rivera, JO | 1 |
| Cha, YJ | 1 |
| Pearson, VE | 1 |
| de Paz, S | 1 |
| Martín, AB | 1 |
| Iglesias, A | 1 |
| Domínguez, AR | 1 |
| Warner, KK | 1 |
| Visconti, JA | 1 |
| Tschampel, MM | 1 |
| Vidt, DG | 1 |
| Chiu, AG | 1 |
| Krowiak, EJ | 1 |
| Deeb, ZE | 1 |
| Howes, LG | 1 |
| Tran, D | 1 |
3 reviews available for losartan and Angioedema
| Article | Year |
|---|---|
ACE inhibitor- versus angiotensin II blocker-induced cough and angioedema.
Topics: Angioedema; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihyperten | 1998 |
Angiotensin II receptor blockers in patients with ACE inhibitor-induced angioedema.
Topics: Angioedema; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Humans; Losa | 2000 |
Can angiotensin receptor antagonists be used safely in patients with previous ACE inhibitor-induced angioedema?
Topics: Angioedema; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihyperten | 2002 |
25 other studies available for losartan and Angioedema
| Article | Year |
|---|---|
Dose-dependent atorvastatin associated with angioedema.
Topics: Aged; Amlodipine; Angioedema; Antihypertensive Agents; Atorvastatin; Calcium Channel Blockers; Femal | 2022 |
Losartan-Induced Angioedema with Acute Hypoxemic Respiratory Failure (Anaphylaxis): A Case Report.
Topics: Anaphylaxis; Angioedema; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; | 2023 |
Twice-daily versus once-daily lisinopril and losartan for hypertension: Real-world effectiveness and safety.
Topics: Aged; Aged, 80 and over; Angioedema; Antihypertensive Agents; Blood Pressure; Dose-Response Relation | 2020 |
Chronic Abdominal Pain and Cutaneous Swelling.
Topics: Abdominal Pain; Angioedema; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Chroni | 2017 |
Hemilingual Angioedema after Thrombolysis in a Patient on an Angiotensin II Receptor Blocker.
Topics: Administration, Intravenous; Angioedema; Angiotensin II Type 1 Receptor Blockers; Fibrinolytic Agent | 2019 |
Recurrent angioedema after naproxen use in a patient stabilized with losartan.
Topics: Aged; Angioedema; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Drug Antagonism; | 2014 |
Severe Angioedema Associated With Angiotensin-Converting Enzyme Inhibitor Therapy in Two Patients With Pollen-Food Allergy Syndrome.
Topics: Aged; Angioedema; Angiotensin-Converting Enzyme Inhibitors; Humans; Lisinopril; Losartan; Male; Midd | 2015 |
Angiotensin receptor blocker-induced visceral angioedema.
Topics: Abdominal Pain; Adult; Angioedema; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme I | 2015 |
Losartan associated anaphylaxis and angioneurotic oedema.
Topics: Adult; Anaphylaxis; Angioedema; Antihypertensive Agents; Epinephrine; Female; Humans; Hypertension; | 2010 |
[Angioedema due to losartan].
Topics: Aged; Allopurinol; Angioedema; Angiotensin II Type 2 Receptor Blockers; Bradykinin; Diphenhydramine; | 2011 |
A case of losartan induced angioedema.
Topics: Angioedema; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Female; Humans; Losart | 2010 |
Angiotensin II receptor blocker-associated angioedema: on the heels of ACE inhibitor angioedema.
Topics: Adult; Angioedema; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme I | 2002 |
Angioedema and AT1 receptor blockers: proceed with caution.
Topics: Angioedema; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting | 2003 |
Hereditary angioedema type III, angioedema associated with angiotensin II receptor antagonists, and female sex.
Topics: Aged; Angioedema; Angiotensin Receptor Antagonists; Antihypertensive Agents; Female; Humans; Losarta | 2004 |
Angioedema induced by the angiotensin II blocker losartan.
Topics: Angioedema; Angiotensin Receptor Antagonists; Antihypertensive Agents; Biphenyl Compounds; Humans; I | 1995 |
Accupril- and Cozaar-induced angioedema in the same patient.
Topics: Angioedema; Antihypertensive Agents; Biphenyl Compounds; Humans; Imidazoles; Isoquinolines; Losartan | 1996 |
Angioedema of the intestine.
Topics: Angioedema; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihyperten | 1996 |
Angioedema associated with angiotensin II receptor antagonist losartan.
Topics: Angioedema; Angiotensin Receptor Antagonists; Antihypertensive Agents; Biphenyl Compounds; Female; H | 1997 |
Angioneurotic edema attributed to the use of losartan.
Topics: Adult; Aged; Angioedema; Angiotensin Receptor Antagonists; Anti-Arrhythmia Agents; Antihypertensive | 1998 |
Angioedema due to losartan.
Topics: Angioedema; Angiotensin Receptor Antagonists; Antihypertensive Agents; Face; Female; Humans; Losarta | 1999 |
Losartan-induced angioedema.
Topics: Angioedema; Antihypertensive Agents; Gout; Humans; Hypertension; Losartan; Male; Middle Aged | 1999 |
Angioedema due to losartan.
Topics: Acute Kidney Injury; Angioedema; Antihypertensive Agents; Female; Humans; Hypertension, Renal; Losar | 1999 |
[Angioedema-urticaria caused by angiotensin-converting enzyme inhibitors and angiotensin II receptor antagonists].
Topics: Aged; Aged, 80 and over; Angioedema; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme | 1999 |
Can angiotensin II receptor blockers be used in patients who have developed a cough or angioedema as a result of taking an ACE inhibitor?
Topics: Acrylates; Angioedema; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzy | 2001 |
Angioedema associated with angiotensin II receptor antagonists: challenging our knowledge of angioedema and its etiology.
Topics: Aged; Angioedema; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihy | 2001 |