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losartan and Anesthesia

losartan has been researched along with Anesthesia in 16 studies

Losartan: An antagonist of ANGIOTENSIN TYPE 1 RECEPTOR with antihypertensive activity due to the reduced pressor effect of ANGIOTENSIN II.
losartan : A biphenylyltetrazole where a 1,1'-biphenyl group is attached at the 5-position and has an additional trisubstituted imidazol-1-ylmethyl group at the 4'-position

Anesthesia: A state characterized by loss of feeling or sensation. This depression of nerve function is usually the result of pharmacologic action and is induced to allow performance of surgery or other painful procedures.

Research Excerpts

ExcerptRelevanceReference
"The authors aimed to test the hypothesis that xenon anesthesia limits adverse hypotensive effects of losartan during acute hemorrhage."7.76Xenon/remifentanil anesthesia protects against adverse effects of losartan on hemodynamic challenges induced by anesthesia and acute blood loss. ( Boemke, W; Francis, RC; Klein, A; Philippi-Höhne, C; Pickerodt, PA; Reyle-Hahn, MS, 2010)
"after a baseline awake period, anesthesia was induced in the dogs with propofol and maintained with xenon/remifentanil (baseline anesthesia)."7.74ETA-receptor blockade impairs vasoconstriction after hemorrhage in xenon-anesthetized dogs treated with an AT1-receptor antagonist. ( Boemke, W; Francis, RC; Höhne, C; Kaisers, U; Klein, A; Pickerodt, P, 2008)
"We conclude that the sympathoadrenal system is still the major determinant for blood pressure maintenance during isoflurane anesthesia in sheep."7.71Losartan increases renal blood flow during isoflurane anesthesia in sheep. ( Eriksson, S; Rundgren, M; Ullman, J, 2001)
"The aim of the present study was to analyze differences in cough induction between losartan and lisinopril in both anaesthetized and awake rabbits, i."3.79Comparison between the effects of lisinopril and losartan on the cougn reflex in anesthetized and awake rabbits. ( Bongianni, F; Cinelli, E; Evangelista, S; Mutolo, D; Pantaleo, T, 2013)
"The authors aimed to test the hypothesis that xenon anesthesia limits adverse hypotensive effects of losartan during acute hemorrhage."3.76Xenon/remifentanil anesthesia protects against adverse effects of losartan on hemodynamic challenges induced by anesthesia and acute blood loss. ( Boemke, W; Francis, RC; Klein, A; Philippi-Höhne, C; Pickerodt, PA; Reyle-Hahn, MS, 2010)
"after a baseline awake period, anesthesia was induced in the dogs with propofol and maintained with xenon/remifentanil (baseline anesthesia)."3.74ETA-receptor blockade impairs vasoconstriction after hemorrhage in xenon-anesthetized dogs treated with an AT1-receptor antagonist. ( Boemke, W; Francis, RC; Höhne, C; Kaisers, U; Klein, A; Pickerodt, P, 2008)
"We conclude that the sympathoadrenal system is still the major determinant for blood pressure maintenance during isoflurane anesthesia in sheep."3.71Losartan increases renal blood flow during isoflurane anesthesia in sheep. ( Eriksson, S; Rundgren, M; Ullman, J, 2001)
"When losartan was administered in a single bolus dose, efficacy was evident until the 7th min (p=0."1.36Hypertension study in anaesthetized rabbits: protocol proposal for AT1 antagonists screening. ( Iliodromitis, EK; Kokotos, G; Kremastinos, DT; Mavromoustakos, TM; Moutevelis-Minakakis, P; Politi, AP; Triantafyllidi, H; Zervou, MV; Zoga, AA; Zoumpoulakis, PG, 2010)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (37.50)18.2507
2000's7 (43.75)29.6817
2010's3 (18.75)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Mutolo, D1
Cinelli, E1
Bongianni, F1
Evangelista, S1
Pantaleo, T1
Höhne, C1
Francis, RC2
Pickerodt, P1
Klein, A2
Kaisers, U1
Boemke, W2
Politi, AP1
Zervou, MV1
Triantafyllidi, H1
Zoumpoulakis, PG1
Mavromoustakos, TM1
Zoga, AA1
Moutevelis-Minakakis, P1
Kokotos, G1
Iliodromitis, EK1
Kremastinos, DT1
Philippi-Höhne, C1
Pickerodt, PA1
Reyle-Hahn, MS1
Luippold, G1
Max, A1
Albinus, M1
Osswald, H1
Mühlbauer, B1
Rocha, I1
Brás-Rosário, L1
Amparo-Barros, M1
Silva-Carvalho, L1
Molinari, C2
Battaglia, A2
Grossini, E2
Florio, S1
Mary, DA2
Vassanelli, C2
Vacca, G2
Richer-Giudicelli, C1
Domergue, V1
Gonzalez, MF1
Messadi, E1
Azizi, M1
Giudicelli, JF2
Ménard, J1
Richard, V1
Ghaleh, B1
Berdeaux, A1
Lambert, C1
Kifor, I1
Williams, GH1
Vickers, MA1
Sullivan, MP1
Jodbert, P1
Dluhy, RG1
Vallon, V1
Heyne, N1
Richter, K1
Khosla, MC1
Fechter, K1
Fitzgerald, SM1
Evans, RG1
Bergström, G1
Anderson, WP1
Ullman, J1
Eriksson, S1
Rundgren, M1
Ruggeri, P1
Surico, N1
Suzuki, Y1
Matsumura, Y1
Egi, Y1
Morimoto, S1

Other Studies

16 other studies available for losartan and Anesthesia

ArticleYear
Comparison between the effects of lisinopril and losartan on the cougn reflex in anesthetized and awake rabbits.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2013, Volume: 64, Issue:2

    Topics: Administration, Inhalation; Administration, Intravenous; Anesthesia; Angiotensin II Type 1 Receptor

2013
ETA-receptor blockade impairs vasoconstriction after hemorrhage in xenon-anesthetized dogs treated with an AT1-receptor antagonist.
    Canadian journal of physiology and pharmacology, 2008, Volume: 86, Issue:6

    Topics: Anesthesia; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Atrasentan; Blood Pres

2008
Hypertension study in anaesthetized rabbits: protocol proposal for AT1 antagonists screening.
    Journal of the renin-angiotensin-aldosterone system : JRAAS, 2010, Volume: 11, Issue:2

    Topics: Anesthesia; Angiotensin II Type 1 Receptor Blockers; Animals; Blood Pressure; Hypertension; Imidazol

2010
Xenon/remifentanil anesthesia protects against adverse effects of losartan on hemodynamic challenges induced by anesthesia and acute blood loss.
    Shock (Augusta, Ga.), 2010, Volume: 34, Issue:6

    Topics: Anesthesia; Angiotensin Receptor Antagonists; Animals; Blood Pressure; Dogs; Female; Hemodynamics; H

2010
Role of the renin-angiotensin system in the compensation of quinpirole-induced blood pressure decrease.
    Naunyn-Schmiedeberg's archives of pharmacology, 2003, Volume: 367, Issue:5

    Topics: Anesthesia; Angiotensin II; Animals; Blood Pressure; Denervation; Dose-Response Relationship, Drug;

2003
Angiotensin AT1 receptor antagonist losartan and the defence reaction in the anaesthetised rat. Effect on the carotid chemoreflex.
    Experimental physiology, 2003, Volume: 88, Issue:3

    Topics: Anesthesia; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Blood Pressur

2003
Activation of the renin-angiotensin system contributes to the peripheral vasoconstriction reflexly caused by stomach distension in anaesthetized pigs.
    Experimental physiology, 2003, Volume: 88, Issue:3

    Topics: Anesthesia; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Catheterization; Cor

2003
Haemodynamic effects of dual blockade of the renin-angiotensin system in spontaneously hypertensive rats: influence of salt.
    Journal of hypertension, 2004, Volume: 22, Issue:3

    Topics: Anesthesia; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressu

2004
Comparison of the effects of EXP3174, an angiotensin II antagonist and enalaprilat on myocardial infarct size in anaesthetized dogs.
    British journal of pharmacology, 1993, Volume: 110, Issue:3

    Topics: Anesthesia; Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Coronar

1993
Mechanisms of angiotensin II chronotropic effect in anaesthetized dogs.
    British journal of pharmacology, 1995, Volume: 115, Issue:5

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Alkaloids; Anesthesia; Angiotensin II; An

1995
Tissue angiotensin II as a modulator of erectile function. I. Angiotensin peptide content, secretion and effects in the corpus cavernosum.
    The Journal of urology, 1997, Volume: 157, Issue:5

    Topics: Alprostadil; Anesthesia; Angiotensin II; Animals; Dogs; Humans; Injections; Losartan; Male; Papaveri

1997
[7-D-ALA]-angiotensin 1-7 blocks renal actions of angiotensin 1-7 in the anesthetized rat.
    Journal of cardiovascular pharmacology, 1998, Volume: 32, Issue:1

    Topics: Anesthesia; Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Kidney; Kidney Function

1998
Renal hemodynamic responses to intrarenal infusion of ligands for the putative angiotensin IV receptor in anesthetized rats.
    Journal of cardiovascular pharmacology, 1999, Volume: 34, Issue:2

    Topics: Anesthesia; Angiotensin II; Animals; Hemodynamics; Hemoglobins; Kidney; Losartan; Male; Peptide Frag

1999
Losartan increases renal blood flow during isoflurane anesthesia in sheep.
    Acta anaesthesiologica Scandinavica, 2001, Volume: 45, Issue:9

    Topics: Anesthesia; Anesthetics, Inhalation; Animals; Antihypertensive Agents; Female; Hemodynamics; Hindlim

2001
The role of activation of the renin-angiotensin system on the reflex regional vasoconstriction caused by distension of the uterus in anaesthetized pigs.
    Autonomic neuroscience : basic & clinical, 2001, Oct-08, Volume: 93, Issue:1-2

    Topics: Anesthesia; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Cath

2001
Effects of Losartan, a nonpeptide angiotensin II receptor antagonist, on norepinephrine overflow and antidiuresis induced by stimulation of renal nerves in anesthetized dogs.
    The Journal of pharmacology and experimental therapeutics, 1992, Volume: 263, Issue:3

    Topics: Anesthesia; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Diuresis;

1992