losartan has been researched along with Amyloidosis in 3 studies
Losartan: An antagonist of ANGIOTENSIN TYPE 1 RECEPTOR with antihypertensive activity due to the reduced pressor effect of ANGIOTENSIN II.
losartan : A biphenylyltetrazole where a 1,1'-biphenyl group is attached at the 5-position and has an additional trisubstituted imidazol-1-ylmethyl group at the 4'-position
Amyloidosis: A group of sporadic, familial and/or inherited, degenerative, and infectious disease processes, linked by the common theme of abnormal protein folding and deposition of AMYLOID. As the amyloid deposits enlarge they displace normal tissue structures, causing disruption of function. Various signs and symptoms depend on the location and size of the deposits.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To investigate the effect of the angiotensin II receptor antagonist losartan on proteinuria in secondary amyloidosis cases." | 9.10 | Long-term effects of losartan on proteinuria and renal function in patients with renal amyloidosis. ( Dilek, K; Ersoy, A; Güllülü, M; Ozdemir, B; Usta, M; Yavuz, M; Yurtkuran, M, 2002) |
| " In this study, we intended to study the effect of losartan, as an ATII receptor antagonist, on proteinuria and renal functions in patients with normotensive secondary amyloidosis." | 9.09 | Effect of losartan treatment on the proteinuria in normotensive patients having proteinuria due to secondary amyloidosis. ( Bilen, H; Cetinkaya, R; Odabas, AR; Selcuk, Y, 2001) |
| " We tested the curative potential of the non brain-penetrant ACEi enalapril (3 mg/kg/day) administered for 3 months either alone or in combination with the brain penetrant ARB losartan (10 mg/kg/day) in aged (∼15 months) transgenic mice overexpressing a mutated form of the human amyloid-β protein precursor (AβPP, thereafter APP mice)." | 5.43 | Enalapril Alone or Co-Administered with Losartan Rescues Cerebrovascular Dysfunction, but not Mnemonic Deficits or Amyloidosis in a Mouse Model of Alzheimer's Disease. ( Aboulkassim, T; Hamel, E; Imboden, H; Nicolakakis, N; Ongali, B; Tong, XK, 2016) |
| "To investigate the effect of the angiotensin II receptor antagonist losartan on proteinuria in secondary amyloidosis cases." | 5.10 | Long-term effects of losartan on proteinuria and renal function in patients with renal amyloidosis. ( Dilek, K; Ersoy, A; Güllülü, M; Ozdemir, B; Usta, M; Yavuz, M; Yurtkuran, M, 2002) |
| " We tested the curative potential of the non brain-penetrant ACEi enalapril (3 mg/kg/day) administered for 3 months either alone or in combination with the brain penetrant ARB losartan (10 mg/kg/day) in aged (∼15 months) transgenic mice overexpressing a mutated form of the human amyloid-β protein precursor (AβPP, thereafter APP mice)." | 1.43 | Enalapril Alone or Co-Administered with Losartan Rescues Cerebrovascular Dysfunction, but not Mnemonic Deficits or Amyloidosis in a Mouse Model of Alzheimer's Disease. ( Aboulkassim, T; Hamel, E; Imboden, H; Nicolakakis, N; Ongali, B; Tong, XK, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ongali, B | 1 |
| Nicolakakis, N | 1 |
| Tong, XK | 1 |
| Aboulkassim, T | 1 |
| Imboden, H | 1 |
| Hamel, E | 1 |
| Odabas, AR | 1 |
| Cetinkaya, R | 1 |
| Selcuk, Y | 1 |
| Bilen, H | 1 |
| Dilek, K | 1 |
| Usta, M | 1 |
| Ersoy, A | 1 |
| Ozdemir, B | 1 |
| Yavuz, M | 1 |
| Güllülü, M | 1 |
| Yurtkuran, M | 1 |
2 trials available for losartan and Amyloidosis
| Article | Year |
|---|---|
Effect of losartan treatment on the proteinuria in normotensive patients having proteinuria due to secondary amyloidosis.
Topics: Adult; Amyloidosis; Angiotensin Receptor Antagonists; Antihypertensive Agents; Blood Pressure; Creat | 2001 |
Long-term effects of losartan on proteinuria and renal function in patients with renal amyloidosis.
Topics: Adult; Amyloidosis; Angiotensin Receptor Antagonists; Creatinine; Female; Humans; Kidney; Kidney Dis | 2002 |
1 other study available for losartan and Amyloidosis
| Article | Year |
|---|---|
Enalapril Alone or Co-Administered with Losartan Rescues Cerebrovascular Dysfunction, but not Mnemonic Deficits or Amyloidosis in a Mouse Model of Alzheimer's Disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloidosis; Analysis of V | 2016 |