losartan has been researched along with Allodynia in 8 studies
Losartan: An antagonist of ANGIOTENSIN TYPE 1 RECEPTOR with antihypertensive activity due to the reduced pressor effect of ANGIOTENSIN II.
losartan : A biphenylyltetrazole where a 1,1'-biphenyl group is attached at the 5-position and has an additional trisubstituted imidazol-1-ylmethyl group at the 4'-position
| Excerpt | Relevance | Reference |
|---|---|---|
| "Losartan prevented visceral allodynia and colonic hyperpermeability in rat IBS models." | 7.96 | Losartan improves visceral sensation and gut barrier in a rat model of irritable bowel syndrome. ( Miyagishi, S; Nozu, R; Nozu, T; Okumura, T; Takakusaki, K, 2020) |
| " Delayed exercise after complex orthopaedic trauma results in decreased muscle fibrosis and improved pain Losartan, an angiotensin-receptor blocker with anti-fibrotic abilities, recapitulates the effect of exercise on post-injury recovery and may provide an enhanced recovery option for those who are unable to exercise after injury ABSTRACT: Chronic pain and disability after limb injury are major public health problems." | 3.96 | Angiotensin receptor blockade mimics the effect of exercise on recovery after orthopaedic trauma by decreasing pain and improving muscle regeneration. ( Clark, JD; Forman, TE; Goodman, SB; Paine, P; Pajarinen, J; Quarta, M; Rando, TA; Takemura, Y; Tawfik, VL, 2020) |
| "Losartan prevented visceral allodynia and colonic hyperpermeability in rat IBS models." | 3.96 | Losartan improves visceral sensation and gut barrier in a rat model of irritable bowel syndrome. ( Miyagishi, S; Nozu, R; Nozu, T; Okumura, T; Takakusaki, K, 2020) |
| " Spontaneous and evoked pain behaviors were assessed before and after acute and chronic administration of Ang-(1-7)." | 1.43 | Angiotensin-(1-7)/Mas receptor as an antinociceptive agent in cancer-induced bone pain. ( Arnold, MR; Forte, BL; Hay, M; Largent-Milnes, TM; Slosky, LM; Staatz, WD; Vanderah, TW; Zhang, H, 2016) |
| "Treatment with losartan decreased neutrophil recruitment, hypernociception and the production of TNF-α, IL-1β and chemokine (C-X-C motif) ligand 1 in mice subjected to AIA." | 1.39 | Mechanisms of the anti-inflammatory actions of the angiotensin type 1 receptor antagonist losartan in experimental models of arthritis. ( Bader, M; Barroso, LC; Coelho, FM; Costa, VV; Oliveira, ML; Queiroz-Junior, CM; Santos, RA; Silva, AC; Silva, TA; Silveira, KD; Sousa, LF; Teixeira, MM; Vieira, AT, 2013) |
| "This hyperalgesia was significantly attenuated by local administration of the AT(1) antagonist losartan." | 1.35 | Microinjection of angiotensin II in the caudal ventrolateral medulla induces hyperalgesia. ( Albino-Teixeira, A; Marques-Lopes, J; Morato, M; Patinha, D; Pinho, D; Pinto, M; Tavares, I, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 4 (50.00) | 24.3611 |
| 2020's | 3 (37.50) | 2.80 |
| Authors | Studies |
|---|---|
| Tawfik, VL | 1 |
| Quarta, M | 1 |
| Paine, P | 1 |
| Forman, TE | 1 |
| Pajarinen, J | 1 |
| Takemura, Y | 1 |
| Goodman, SB | 1 |
| Rando, TA | 1 |
| Clark, JD | 1 |
| Nozu, T | 1 |
| Miyagishi, S | 1 |
| Nozu, R | 1 |
| Takakusaki, K | 1 |
| Okumura, T | 1 |
| Hong, Y | 1 |
| Wu, W | 1 |
| Wang, S | 1 |
| Hao, Q | 1 |
| Zheng, H | 1 |
| Li, S | 1 |
| Zhang, X | 1 |
| Sun, R | 1 |
| Kalynovska, N | 1 |
| Diallo, M | 1 |
| Palecek, J | 1 |
| Kim, E | 1 |
| Hwang, SH | 1 |
| Kim, HK | 2 |
| Abdi, S | 1 |
| Silveira, KD | 1 |
| Coelho, FM | 1 |
| Vieira, AT | 1 |
| Barroso, LC | 1 |
| Queiroz-Junior, CM | 1 |
| Costa, VV | 1 |
| Sousa, LF | 1 |
| Oliveira, ML | 1 |
| Bader, M | 1 |
| Silva, TA | 1 |
| Santos, RA | 1 |
| Silva, AC | 1 |
| Teixeira, MM | 1 |
| Forte, BL | 1 |
| Slosky, LM | 1 |
| Zhang, H | 1 |
| Arnold, MR | 1 |
| Staatz, WD | 1 |
| Hay, M | 1 |
| Largent-Milnes, TM | 1 |
| Vanderah, TW | 1 |
| Marques-Lopes, J | 1 |
| Pinto, M | 1 |
| Pinho, D | 1 |
| Morato, M | 1 |
| Patinha, D | 1 |
| Albino-Teixeira, A | 1 |
| Tavares, I | 1 |
8 other studies available for losartan and Allodynia
| Article | Year |
|---|---|
Angiotensin receptor blockade mimics the effect of exercise on recovery after orthopaedic trauma by decreasing pain and improving muscle regeneration.
Topics: Angiotensin Receptor Antagonists; Animals; Fibrosis; Fractures, Bone; Hyperalgesia; Losartan; Mice; | 2020 |
Losartan improves visceral sensation and gut barrier in a rat model of irritable bowel syndrome.
Topics: Animals; Colon; Corticotropin-Releasing Hormone; Disease Models, Animal; Hyperalgesia; Irritable Bow | 2020 |
Angiotensin II type 1 receptor blockade attenuates posttraumatic stress disorder-related chronic pain by inhibiting glial activation in the spinal cord.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Astrocytes; Chronic Pain; Hippocam | 2021 |
Losartan treatment attenuates the development of neuropathic thermal hyperalgesia induced by peripheral nerve injury in rats.
Topics: Animals; Disease Models, Animal; Ganglia, Spinal; Hyperalgesia; Losartan; Male; Neuralgia; Pain Meas | 2019 |
Losartan, an Angiotensin II Type 1 Receptor Antagonist, Alleviates Mechanical Hyperalgesia in a Rat Model of Chemotherapy-Induced Neuropathic Pain by Inhibiting Inflammatory Cytokines in the Dorsal Root Ganglia.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Cytokines; Disease Models, Animal; Ganglia, Spinal | 2019 |
Mechanisms of the anti-inflammatory actions of the angiotensin type 1 receptor antagonist losartan in experimental models of arthritis.
Topics: Angiotensin I; Angiotensin II Type 1 Receptor Blockers; Animals; Anti-Inflammatory Agents, Non-Stero | 2013 |
Angiotensin-(1-7)/Mas receptor as an antinociceptive agent in cancer-induced bone pain.
Topics: Analgesics; Analysis of Variance; Angiotensin I; Angiotensin II Type 1 Receptor Blockers; Angiotensi | 2016 |
Microinjection of angiotensin II in the caudal ventrolateral medulla induces hyperalgesia.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Blood Pressure; Cholera Toxin; Hyp | 2009 |