losartan has been researched along with Adenoma, Prostatic in 6 studies
Losartan: An antagonist of ANGIOTENSIN TYPE 1 RECEPTOR with antihypertensive activity due to the reduced pressor effect of ANGIOTENSIN II.
losartan : A biphenylyltetrazole where a 1,1'-biphenyl group is attached at the 5-position and has an additional trisubstituted imidazol-1-ylmethyl group at the 4'-position
| Excerpt | Relevance | Reference |
|---|---|---|
| "We investigated the therapeutic effects of losartan, an angiotensin II type 1 receptor blocker, on prostatic hyperplasia in spontaneously hypertensive rats (SHRs)." | 8.02 | Therapeutic effects of losartan on prostatic hyperplasia in spontaneously hypertensive rats. ( Higashi, Y; Karashima, T; Nagao, Y; Saito, M; Shimizu, S; Shimizu, T, 2021) |
| "To investigate the effect of losartan on prostatic hyperplasia in spontaneous hypertension rats (SHRs) and its pathophysiological mechanism." | 7.78 | [Inhibitory effect of losartan on prostatic hyperplasia in spontaneous hypertension rats and its pathophysiological mechanism]. ( Dong, LN; Qu, XB; Shen, F; Zeng, XF; Zhang, XY; Zhao, XK, 2012) |
| "We investigated the therapeutic effects of losartan, an angiotensin II type 1 receptor blocker, on prostatic hyperplasia in spontaneously hypertensive rats (SHRs)." | 4.02 | Therapeutic effects of losartan on prostatic hyperplasia in spontaneously hypertensive rats. ( Higashi, Y; Karashima, T; Nagao, Y; Saito, M; Shimizu, S; Shimizu, T, 2021) |
| "To investigate the effect of losartan on prostatic hyperplasia in spontaneous hypertension rats (SHRs) and its pathophysiological mechanism." | 3.78 | [Inhibitory effect of losartan on prostatic hyperplasia in spontaneous hypertension rats and its pathophysiological mechanism]. ( Dong, LN; Qu, XB; Shen, F; Zeng, XF; Zhang, XY; Zhao, XK, 2012) |
| "To assess whether angiotensin II (Ang II), important in hypertension and highly expressed in benign prostatic hyperplasia (BPH), is involved in prostate growth, by analysing changes in the histological composition, tissue apoptotic status and level of transforming growth factor-beta1 (TGFbeta1) induced by an Ang II type 1 receptor blocker, losartan, in the prostates of spontaneously hypertensive (SH) rats." | 3.74 | Angiotension II receptor 1 blocker modifies the expression of apoptosis-related proteins and transforming growth factor-beta1 in prostate tissue of spontaneously hypertensive rats. ( Guo, YL; Jin, J; Yu, W; Zhang, ZW; Zhao, YY, 2007) |
| "The significant association of benign prostatic hyperplasia (BPH) and hypertension indicates a common pathophysiological factor for both diseases." | 1.36 | Transforming growth factor beta1 mediates apoptotic activity of angiotensin II type I receptor blocker on prostate epithelium in vitro. ( Jin, J; Peng, J; Yu, W; Zhao, Y; Zheng, L, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (50.00) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 1 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Shimizu, S | 1 |
| Nagao, Y | 1 |
| Shimizu, T | 1 |
| Higashi, Y | 1 |
| Karashima, T | 1 |
| Saito, M | 1 |
| Zhao, Y | 1 |
| Peng, J | 1 |
| Zheng, L | 1 |
| Yu, W | 2 |
| Jin, J | 2 |
| Shen, F | 1 |
| Dong, LN | 1 |
| Zhang, XY | 1 |
| Zhao, XK | 1 |
| Zeng, XF | 1 |
| Qu, XB | 1 |
| Wennemuth, G | 1 |
| Aumüller, G | 1 |
| Zhao, YY | 1 |
| Zhang, ZW | 1 |
| Guo, YL | 1 |
| Fabiani, ME | 1 |
| Sourial, M | 1 |
| Thomas, WG | 1 |
| Johnston, CI | 2 |
| Frauman, AG | 1 |
6 other studies available for losartan and Adenoma, Prostatic
| Article | Year |
|---|---|
Therapeutic effects of losartan on prostatic hyperplasia in spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Hypertension; Losartan; Male; Malondialdehyde; Oxi | 2021 |
Transforming growth factor beta1 mediates apoptotic activity of angiotensin II type I receptor blocker on prostate epithelium in vitro.
Topics: Analysis of Variance; Angiotensin II Type 1 Receptor Blockers; Apoptosis; Blotting, Western; Cell Co | 2010 |
[Inhibitory effect of losartan on prostatic hyperplasia in spontaneous hypertension rats and its pathophysiological mechanism].
Topics: Angiotensin II; Animals; Antihypertensive Agents; Hypertension; Insulin-Like Growth Factor I; Interl | 2012 |
Angiotensin II-mediated calcium signals and mitogenesis in human prostate stromal cell line hPCPs.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Blotting, Western; Buffers; Calcium; Calciu | 2005 |
Angiotension II receptor 1 blocker modifies the expression of apoptosis-related proteins and transforming growth factor-beta1 in prostate tissue of spontaneously hypertensive rats.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; bcl-2-Associated X Protein; Blotti | 2007 |
Angiotensin II enhances noradrenaline release from sympathetic nerves of the rat prostate via a novel angiotensin receptor: implications for the pathophysiology of benign prostatic hyperplasia.
Topics: Analysis of Variance; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-C | 2001 |