losartan has been researched along with Adamantiades-Behcet Disease in 2 studies
Losartan: An antagonist of ANGIOTENSIN TYPE 1 RECEPTOR with antihypertensive activity due to the reduced pressor effect of ANGIOTENSIN II.
losartan : A biphenylyltetrazole where a 1,1'-biphenyl group is attached at the 5-position and has an additional trisubstituted imidazol-1-ylmethyl group at the 4'-position
| Excerpt | Relevance | Reference |
|---|---|---|
| " As this seems not to be due to colchicine treatment, our hypothesis is that inflammation related to BD might have caused the down-regulation of the CYP2C9 activity due to immune cytokine reactions." | 3.81 | Lower CYP2C9 activity in Turkish patients with Behçet's disease compared to healthy subjects: a down-regulation due to inflammation? ( Akdogan, A; Babaoglu, MO; Bertilsson, L; Bozkurt, A; Goktaş, MT; Hatta, F; Helldén, A; Kalkisim, S; Karaca, O; Kilic, L; Yasar, U, 2015) |
| " When fluconazole, a potent inhibitor of CYP2C9, was added to the treatment regimen, the patient developed ataxia, tremor, fatigue, slurred speech and somnolence, indicating phenytoin intoxication." | 3.76 | Fluconazole-induced intoxication with phenytoin in a patient with ultra-high activity of CYP2C9. ( Bergman, U; Bertilsson, L; Engström Hellgren, K; Helldén, A; Masquelier, M; Nilsson Remahl, I; Odar-Cederlöf, I; Ramsjö, M, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Goktaş, MT | 1 |
| Hatta, F | 1 |
| Karaca, O | 1 |
| Kalkisim, S | 1 |
| Kilic, L | 1 |
| Akdogan, A | 1 |
| Babaoglu, MO | 1 |
| Bozkurt, A | 1 |
| Helldén, A | 2 |
| Bertilsson, L | 2 |
| Yasar, U | 1 |
| Bergman, U | 1 |
| Engström Hellgren, K | 1 |
| Masquelier, M | 1 |
| Nilsson Remahl, I | 1 |
| Odar-Cederlöf, I | 1 |
| Ramsjö, M | 1 |
2 other studies available for losartan and Adamantiades-Behcet Disease
| Article | Year |
|---|---|
Lower CYP2C9 activity in Turkish patients with Behçet's disease compared to healthy subjects: a down-regulation due to inflammation?
Topics: Adult; Aged; Alleles; Behcet Syndrome; Chromatography, High Pressure Liquid; Colchicine; Cytochrome | 2015 |
Fluconazole-induced intoxication with phenytoin in a patient with ultra-high activity of CYP2C9.
Topics: Alleles; Angiotensin II Type 1 Receptor Blockers; Anticonvulsants; Aryl Hydrocarbon Hydroxylases; At | 2010 |