losartan has been researched along with Acute Respiratory Distress Syndrome in 4 studies
Losartan: An antagonist of ANGIOTENSIN TYPE 1 RECEPTOR with antihypertensive activity due to the reduced pressor effect of ANGIOTENSIN II.
losartan : A biphenylyltetrazole where a 1,1'-biphenyl group is attached at the 5-position and has an additional trisubstituted imidazol-1-ylmethyl group at the 4'-position
| Excerpt | Relevance | Reference |
|---|---|---|
| "Losartan (10 mg/kg) was administered by gavage daily, starting from 1 d before LPS stimulation." | 1.39 | Angiotensin-(1-7) attenuates lung fibrosis by way of Mas receptor in acute lung injury. ( Chen, Q; Huang, Y; Liu, L; Pan, C; Qiu, H; Yang, Y, 2013) |
| "Pretreatment with Losartan attenuated ventilator-induced lung injury and prevented the increase in total protein, the number of apoptotic cells, W/D ratio, MPO, and neutrophil counts caused by high volume ventilation." | 1.35 | Losartan attenuates ventilator-induced lung injury. ( Feng, D; Li, K; Wang, L; Wu, Q; Yao, S, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, Q | 1 |
| Yang, Y | 1 |
| Huang, Y | 1 |
| Pan, C | 1 |
| Liu, L | 1 |
| Qiu, H | 1 |
| Wösten-van Asperen, RM | 1 |
| Lutter, R | 1 |
| Specht, PA | 1 |
| Moll, GN | 1 |
| van Woensel, JB | 1 |
| van der Loos, CM | 1 |
| van Goor, H | 1 |
| Kamilic, J | 1 |
| Florquin, S | 1 |
| Bos, AP | 1 |
| Raiden, S | 1 |
| Nahmod, K | 1 |
| Nahmod, V | 1 |
| Semeniuk, G | 1 |
| Pereira, Y | 1 |
| Alvarez, C | 1 |
| Giordano, M | 1 |
| Geffner, JR | 1 |
| Yao, S | 1 |
| Feng, D | 1 |
| Wu, Q | 1 |
| Li, K | 1 |
| Wang, L | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Apelin; ACE2 and Biomarkers of Alveolar-capillary Permeability in SARS-cov-2 (COVID-19).[NCT04632732] | 140 participants (Actual) | Observational [Patient Registry] | 2020-10-26 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 other studies available for losartan and Acute Respiratory Distress Syndrome
| Article | Year |
|---|---|
Angiotensin-(1-7) attenuates lung fibrosis by way of Mas receptor in acute lung injury.
Topics: Acute Lung Injury; Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; | 2013 |
Acute respiratory distress syndrome leads to reduced ratio of ACE/ACE2 activities and is prevented by angiotensin-(1-7) or an angiotensin II receptor antagonist.
Topics: Angiotensin I; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme 2; Animals; Bronchoal | 2011 |
Nonpeptide antagonists of AT1 receptor for angiotensin II delay the onset of acute respiratory distress syndrome.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Bordetella bronchiseptica; Bordetella Inf | 2002 |
Losartan attenuates ventilator-induced lung injury.
Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensinogen; Animals; Apoptosis; Bronchoalveolar Lavage | 2008 |