losartan has been researched along with Abnormality, Heart in 4 studies
Losartan: An antagonist of ANGIOTENSIN TYPE 1 RECEPTOR with antihypertensive activity due to the reduced pressor effect of ANGIOTENSIN II.
losartan : A biphenylyltetrazole where a 1,1'-biphenyl group is attached at the 5-position and has an additional trisubstituted imidazol-1-ylmethyl group at the 4'-position
| Excerpt | Relevance | Reference |
|---|---|---|
| "A case of severe early-onset Marfan syndrome (MFS) led us to ask the question: 'Should an ARB, particularly losartan [intervention], compared with beta blockade alone [comparison], be commenced in all paediatric MFS patients [patient] with aortic root dilatation [outcome]?' The current literature was critically appraised to address this question." | 7.81 | Losartan therapy for cardiac disease in paediatricMarfan syndrome. ( Adès, L; Ewans, LJ; Roberts, P, 2015) |
| "Despite the retrospective design of the study and the small sample size, a beneficial effect of losartan therapy was observed in pediatric patients with Marfan syndrome in the mid and long term." | 7.81 | [Aortic root dilatation rate in pediatric patients with Marfan syndrome treated with losartan]. ( Angeli, E; Bonvicini, M; Donti, A; Gargiulo, GD; Guidarini, M; Lovato, L; Mariucci, E; Picchio, FM; Wischmeijer, A, 2015) |
| "A case of severe early-onset Marfan syndrome (MFS) led us to ask the question: 'Should an ARB, particularly losartan [intervention], compared with beta blockade alone [comparison], be commenced in all paediatric MFS patients [patient] with aortic root dilatation [outcome]?' The current literature was critically appraised to address this question." | 3.81 | Losartan therapy for cardiac disease in paediatricMarfan syndrome. ( Adès, L; Ewans, LJ; Roberts, P, 2015) |
| "Despite the retrospective design of the study and the small sample size, a beneficial effect of losartan therapy was observed in pediatric patients with Marfan syndrome in the mid and long term." | 3.81 | [Aortic root dilatation rate in pediatric patients with Marfan syndrome treated with losartan]. ( Angeli, E; Bonvicini, M; Donti, A; Gargiulo, GD; Guidarini, M; Lovato, L; Mariucci, E; Picchio, FM; Wischmeijer, A, 2015) |
| "Losartan is a specific angiotensin II receptor antagonist." | 1.32 | Losartan induced fetal toxicity. ( Aggarwal, R; Malhotra, N; Nayar, B; Singhal, A, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ewans, LJ | 1 |
| Roberts, P | 1 |
| Adès, L | 1 |
| Mariucci, E | 1 |
| Guidarini, M | 1 |
| Donti, A | 1 |
| Lovato, L | 1 |
| Wischmeijer, A | 1 |
| Angeli, E | 1 |
| Gargiulo, GD | 1 |
| Picchio, FM | 1 |
| Bonvicini, M | 1 |
| Geirsson, A | 1 |
| Singh, M | 1 |
| Ali, R | 1 |
| Abbas, H | 1 |
| Li, W | 1 |
| Sanchez, JA | 1 |
| Hashim, S | 1 |
| Tellides, G | 1 |
| Nayar, B | 1 |
| Singhal, A | 1 |
| Aggarwal, R | 1 |
| Malhotra, N | 1 |
4 other studies available for losartan and Abnormality, Heart
| Article | Year |
|---|---|
Losartan therapy for cardiac disease in paediatricMarfan syndrome.
Topics: Angiotensin II Type 1 Receptor Blockers; Aorta; Dilatation, Pathologic; Female; Heart Defects, Conge | 2015 |
[Aortic root dilatation rate in pediatric patients with Marfan syndrome treated with losartan].
Topics: Adolescent; Angiotensin II Type 1 Receptor Blockers; Aortic Valve; Bicuspid Aortic Valve Disease; Ch | 2015 |
Modulation of transforming growth factor-β signaling and extracellular matrix production in myxomatous mitral valves by angiotensin II receptor blockers.
Topics: Angiotensin Receptor Antagonists; Benzimidazoles; Benzoates; Biphenyl Compounds; Cells, Cultured; Co | 2012 |
Losartan induced fetal toxicity.
Topics: Abnormalities, Drug-Induced; Antihypertensive Agents; Female; Fetal Death; Heart Defects, Congenital | 2003 |