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losartan and Abnormalities, Drug-Induced

losartan has been researched along with Abnormalities, Drug-Induced in 6 studies

Losartan: An antagonist of ANGIOTENSIN TYPE 1 RECEPTOR with antihypertensive activity due to the reduced pressor effect of ANGIOTENSIN II.
losartan : A biphenylyltetrazole where a 1,1'-biphenyl group is attached at the 5-position and has an additional trisubstituted imidazol-1-ylmethyl group at the 4'-position

Abnormalities, Drug-Induced: Congenital abnormalities caused by medicinal substances or drugs of abuse given to or taken by the mother, or to which she is inadvertently exposed during the manufacture of such substances. The concept excludes abnormalities resulting from exposure to non-medicinal chemicals in the environment.

Research Excerpts

ExcerptRelevanceReference
"Treatment with Losartan resulted in severe renal abnormalities."5.35Inhibition of Angiotensin II receptors during pregnancy induces malformations in developing rat kidney. ( Ciuffo, GM; Forneris, ML; Fuentes, LB; Sánchez, SI; Seltzer, AM, 2008)
" The mother suffered from essential hypertension and was treated with Cozaar (losartan 50 mg)."3.73Foetal kidney maldevelopment in maternal use of angiotensin II type I receptor antagonists. ( Daïkha-Dahmane, F; Jugie, M; Lenclen, R; Levy-Beff, E, 2006)
"Treatment with Losartan resulted in severe renal abnormalities."1.35Inhibition of Angiotensin II receptors during pregnancy induces malformations in developing rat kidney. ( Ciuffo, GM; Forneris, ML; Fuentes, LB; Sánchez, SI; Seltzer, AM, 2008)
"Losartan is a specific angiotensin II receptor antagonist."1.32Losartan induced fetal toxicity. ( Aggarwal, R; Malhotra, N; Nayar, B; Singhal, A, 2003)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gersak, K1
Cvijic, M1
Cerar, LK1
Nayar, B1
Singhal, A1
Aggarwal, R1
Malhotra, N1
Daïkha-Dahmane, F2
Levy-Beff, E1
Jugie, M1
Lenclen, R1
Sánchez, SI1
Seltzer, AM1
Fuentes, LB1
Forneris, ML1
Ciuffo, GM1
Lambot, MA1
Vermeylen, D1
Noël, JC1
Martinovic, J1
Benachi, A1
Laurent, N1
Gubler, MC1

Other Studies

6 other studies available for losartan and Abnormalities, Drug-Induced

ArticleYear
Angiotensin II receptor blockers in pregnancy: a report of five cases.
    Reproductive toxicology (Elmsford, N.Y.), 2009, Volume: 28, Issue:1

    Topics: Abnormalities, Drug-Induced; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Biphe

2009
Losartan induced fetal toxicity.
    Indian journal of pediatrics, 2003, Volume: 70, Issue:11

    Topics: Abnormalities, Drug-Induced; Antihypertensive Agents; Female; Fetal Death; Heart Defects, Congenital

2003
Foetal kidney maldevelopment in maternal use of angiotensin II type I receptor antagonists.
    Pediatric nephrology (Berlin, Germany), 2006, Volume: 21, Issue:5

    Topics: Abnormalities, Drug-Induced; Adult; Angiotensin II Type 1 Receptor Blockers; Diseases in Twins; Fema

2006
Inhibition of Angiotensin II receptors during pregnancy induces malformations in developing rat kidney.
    European journal of pharmacology, 2008, Jun-24, Volume: 588, Issue:1

    Topics: Abnormalities, Drug-Induced; Aging; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiote

2008
Angiotensin-II-receptor inhibitors in pregnancy.
    Lancet (London, England), 2001, May-19, Volume: 357, Issue:9268

    Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Adult; Antihypertensive Agents; Cesarean Secti

2001
Fetal toxic effects and angiotensin-II-receptor antagonists.
    Lancet (London, England), 2001, Jul-21, Volume: 358, Issue:9277

    Topics: Abnormalities, Drug-Induced; Adult; Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensi

2001