losartan has been researched along with 2019 Novel Coronavirus Disease in 21 studies
Losartan: An antagonist of ANGIOTENSIN TYPE 1 RECEPTOR with antihypertensive activity due to the reduced pressor effect of ANGIOTENSIN II.
losartan : A biphenylyltetrazole where a 1,1'-biphenyl group is attached at the 5-position and has an additional trisubstituted imidazol-1-ylmethyl group at the 4'-position
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 21 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Iwanski, J | 1 |
| Kazmouz, SG | 1 |
| Li, S | 1 |
| Stansfield, B | 1 |
| Salem, TT | 1 |
| Perez-Miller, S | 1 |
| Kazui, T | 1 |
| Jena, L | 1 |
| Uhrlaub, JL | 1 |
| Lick, S | 1 |
| Nikolich-Žugich, J | 1 |
| Konhilas, JP | 1 |
| Gregorio, CC | 1 |
| Khanna, M | 1 |
| Campos, SK | 1 |
| Churko, JM | 1 |
| Zaheer, J | 1 |
| Kim, H | 1 |
| Kim, JS | 1 |
| Loas, G | 1 |
| Le Corre, P | 1 |
| Puskarich, MA | 2 |
| Ingraham, NE | 1 |
| Merck, LH | 1 |
| Driver, BE | 1 |
| Wacker, DA | 1 |
| Black, LP | 1 |
| Jones, AE | 1 |
| Fletcher, CV | 1 |
| South, AM | 1 |
| Murray, TA | 1 |
| Lewandowski, C | 1 |
| Farhat, J | 1 |
| Benoit, JL | 1 |
| Biros, MH | 1 |
| Cherabuddi, K | 1 |
| Chipman, JG | 1 |
| Schacker, TW | 1 |
| Guirgis, FW | 1 |
| Voelker, HT | 1 |
| Koopmeiners, JS | 1 |
| Tignanelli, CJ | 2 |
| Mirjalili, M | 1 |
| Soodejani, MT | 1 |
| Raadabadi, M | 1 |
| Dehghani, A | 1 |
| Salemi, F | 1 |
| Hassan, SSM | 1 |
| Kamel, AH | 1 |
| Fathy, MA | 1 |
| Moovarkumudalvan, B | 1 |
| Geethakumari, AM | 1 |
| Ramadoss, R | 1 |
| Biswas, KH | 1 |
| Mifsud, B | 1 |
| Corrêa, BSG | 1 |
| de Barros, S | 1 |
| Vaz, JB | 1 |
| Peres, MA | 1 |
| Uchiyama, MK | 1 |
| da Silva, AA | 1 |
| Furukawa, LNS | 1 |
| Rothlin, RP | 1 |
| Pelorosso, FG | 1 |
| Duarte, M | 1 |
| Nicolosi, L | 1 |
| Ignacio, FC | 1 |
| Salgado, MV | 1 |
| Vetulli, H | 1 |
| Di Stefano, L | 1 |
| Ram, M | 1 |
| Scharfstein, DO | 1 |
| Li, T | 2 |
| Khanal, P | 1 |
| Baksh, SN | 1 |
| McBee, N | 1 |
| Bengtson, CD | 1 |
| Gadomski, A | 1 |
| Geriak, M | 1 |
| Salathe, MA | 1 |
| Schutte, AE | 1 |
| Victory, J | 1 |
| Bierer, BE | 1 |
| Hanley, DF | 1 |
| Freilich, DA | 1 |
| Ardiana, M | 1 |
| Suryawan, IGR | 1 |
| Hermawan, HO | 1 |
| Harsoyo, PM | 1 |
| Sufiyah, IM | 1 |
| Muhammad, AR | 1 |
| Zaini, BSI | 1 |
| Marin, GH | 1 |
| Zeinalian, M | 1 |
| Salari-Jazi, A | 1 |
| Jannesari, A | 1 |
| Khanahmad, H | 1 |
| Messerli, FH | 1 |
| Siontis, GCM | 1 |
| Rexhaj, E | 1 |
| Shirazi, FM | 1 |
| Banerji, S | 1 |
| Nakhaee, S | 1 |
| Mehrpour, O | 1 |
| Wu, C | 2 |
| Ye, D | 1 |
| Mullick, AE | 1 |
| Li, Z | 3 |
| Danser, AHJ | 1 |
| Daugherty, A | 1 |
| Lu, HS | 1 |
| Nese, M | 1 |
| Riboli, G | 1 |
| Brighetti, G | 1 |
| Sassi, V | 1 |
| Camela, E | 1 |
| Caselli, G | 1 |
| Sassaroli, S | 1 |
| Borlimi, R | 1 |
| Aucoin, M | 1 |
| Cooley, K | 1 |
| Saunders, PR | 1 |
| Carè, J | 1 |
| Anheyer, D | 1 |
| Medina, DN | 1 |
| Cardozo, V | 1 |
| Remy, D | 1 |
| Hannan, N | 1 |
| Garber, A | 1 |
| Velayos, M | 1 |
| Muñoz-Serrano, AJ | 1 |
| Estefanía-Fernández, K | 1 |
| Sarmiento Caldas, MC | 1 |
| Moratilla Lapeña, L | 1 |
| López-Santamaría, M | 1 |
| López-Gutiérrez, JC | 1 |
| Li, J | 1 |
| Zhang, J | 1 |
| Shen, S | 1 |
| Zhang, B | 2 |
| Yu, WW | 1 |
| Toyoda, H | 1 |
| Huang, DQ | 1 |
| Le, MH | 1 |
| Nguyen, MH | 1 |
| Huang, R | 1 |
| Zhu, L | 1 |
| Wang, J | 6 |
| Xue, L | 1 |
| Liu, L | 2 |
| Yan, X | 2 |
| Huang, S | 1 |
| Li, Y | 6 |
| Xu, T | 1 |
| Li, C | 2 |
| Ji, F | 1 |
| Ming, F | 1 |
| Zhao, Y | 2 |
| Cheng, J | 1 |
| Wang, Y | 4 |
| Zhao, H | 1 |
| Hong, S | 1 |
| Chen, K | 2 |
| Zhao, XA | 1 |
| Zou, L | 1 |
| Sang, D | 1 |
| Shao, H | 1 |
| Guan, X | 1 |
| Chen, X | 2 |
| Chen, Y | 4 |
| Wei, J | 1 |
| Zhu, C | 1 |
| Moore, HB | 1 |
| Barrett, CD | 1 |
| Moore, EE | 1 |
| Jhunjhunwala, R | 1 |
| McIntyre, RC | 1 |
| Moore, PK | 1 |
| Hajizadeh, N | 1 |
| Talmor, DS | 1 |
| Sauaia, A | 1 |
| Yaffe, MB | 1 |
| Liu, C | 3 |
| Lin, Y | 1 |
| Dong, Y | 1 |
| Wu, Y | 1 |
| Bao, Y | 1 |
| Yan, H | 2 |
| Ma, J | 1 |
| Fernández-Cuadros, ME | 1 |
| Albaladejo-Florín, MJ | 1 |
| Álava-Rabasa, S | 1 |
| Usandizaga-Elio, I | 1 |
| Martinez-Quintanilla Jimenez, D | 1 |
| Peña-Lora, D | 1 |
| Neira-Borrajo, I | 1 |
| López-Muñoz, MJ | 1 |
| Rodríguez-de-Cía, J | 1 |
| Pérez-Moro, OS | 1 |
| Abdallah, M | 1 |
| Alsaleh, H | 1 |
| Baradwan, A | 1 |
| Alfawares, R | 1 |
| Alobaid, A | 1 |
| Rasheed, A | 1 |
| Soliman, I | 1 |
| Wendel Garcia, PD | 1 |
| Fumeaux, T | 1 |
| Guerci, P | 1 |
| Heuberger, DM | 1 |
| Montomoli, J | 2 |
| Roche-Campo, F | 1 |
| Schuepbach, RA | 1 |
| Hilty, MP | 1 |
| Poloni, TE | 1 |
| Carlos, AF | 1 |
| Cairati, M | 1 |
| Cutaia, C | 1 |
| Medici, V | 1 |
| Marelli, E | 1 |
| Ferrari, D | 1 |
| Galli, A | 1 |
| Bognetti, P | 1 |
| Davin, A | 1 |
| Cirrincione, A | 1 |
| Ceretti, A | 1 |
| Cereda, C | 1 |
| Ceroni, M | 1 |
| Tronconi, L | 1 |
| Vitali, S | 1 |
| Guaita, A | 1 |
| Leeds, JS | 1 |
| Raviprakash, V | 1 |
| Jacques, T | 1 |
| Scanlon, N | 1 |
| Cundall, J | 1 |
| Leeds, CM | 1 |
| Riva, A | 1 |
| Gray, EH | 1 |
| Azarian, S | 1 |
| Zamalloa, A | 1 |
| McPhail, MJW | 1 |
| Vincent, RP | 1 |
| Williams, R | 1 |
| Chokshi, S | 1 |
| Patel, VC | 1 |
| Edwards, LA | 1 |
| Alqarawi, W | 1 |
| Birnie, DH | 1 |
| Golian, M | 1 |
| Nair, GM | 1 |
| Nery, PB | 1 |
| Klein, A | 1 |
| Davis, DR | 1 |
| Sadek, MM | 1 |
| Neilipovitz, D | 1 |
| Johnson, CB | 1 |
| Green, MS | 1 |
| Redpath, C | 1 |
| Miller, DC | 1 |
| Beamer, P | 1 |
| Billheimer, D | 1 |
| Subbian, V | 1 |
| Sorooshian, A | 1 |
| Campbell, BS | 1 |
| Mosier, JM | 1 |
| Novaretti, JV | 1 |
| Astur, DC | 1 |
| Cavalcante, ELB | 1 |
| Kaleka, CC | 1 |
| Amaro, JT | 1 |
| Cohen, M | 1 |
| Huang, W | 1 |
| Ling, Y | 1 |
| Qian, ZP | 1 |
| Zhang, YY | 1 |
| Huang, D | 1 |
| Xu, SB | 1 |
| Liu, XH | 1 |
| Xia, L | 1 |
| Yang, Y | 3 |
| Lu, SH | 1 |
| Lu, HZ | 1 |
| Zhang, R | 2 |
| Ma, JX | 1 |
| Tang, S | 1 |
| Li, CM | 1 |
| Wan, J | 1 |
| Wang, JF | 1 |
| Ma, JQ | 1 |
| Luo, JJ | 1 |
| Chen, HY | 2 |
| Mi, SL | 1 |
| Chen, SY | 1 |
| Su, YG | 1 |
| Ge, JB | 1 |
| Milheiro, SA | 1 |
| Gonçalves, J | 1 |
| Lopes, RMRM | 1 |
| Madureira, M | 1 |
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| Lopes, A | 1 |
| Nogueira, F | 1 |
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| M Piedade, MF | 1 |
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| Florindo, PR | 1 |
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| Castillo-Lora, J | 1 |
| Delley, MF | 1 |
| Laga, SM | 1 |
| Mayer, JM | 1 |
| Sutjarit, N | 1 |
| Thongon, N | 1 |
| Weerachayaphorn, J | 1 |
| Piyachaturawat, P | 1 |
| Suksamrarn, A | 1 |
| Suksen, K | 1 |
| Papachristou, DJ | 1 |
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| Zeng, N | 1 |
| Wang, L | 3 |
| Yan, D | 1 |
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| Zhai, C | 1 |
| Yang, M | 1 |
| Lao, X | 1 |
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| Ma, N | 1 |
| Wang, S | 1 |
| Ye, W | 1 |
| Guo, P | 1 |
| Rahimi, S | 1 |
| Singh, MP | 1 |
| Gupta, J | 1 |
| Nakanishi, I | 1 |
| Ohkubo, K | 1 |
| Shoji, Y | 1 |
| Fujitaka, Y | 1 |
| Shimoda, K | 1 |
| Matsumoto, KI | 1 |
| Fukuhara, K | 1 |
| Hamada, H | 1 |
| van der Boom, T | 1 |
| Gruppen, EG | 1 |
| Lefrandt, JD | 1 |
| Connelly, MA | 1 |
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| Dullaart, RPF | 1 |
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| Bedlack, R | 1 |
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| Meloncelli, S | 1 |
| Divizia, M | 1 |
| Germani, G | 1 |
| Adefegha, SA | 1 |
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| Leal, DB | 1 |
| de Andrade, CM | 1 |
| Schetinger, MR | 1 |
| Martínez-Velasco, A | 1 |
| Perez-Ortiz, AC | 1 |
| Antonio-Aguirre, B | 1 |
| Martínez-Villaseñor, L | 1 |
| Lira-Romero, E | 1 |
| Palacio-Pastrana, C | 1 |
| Zenteno, JC | 1 |
| Ramirez, I | 1 |
| Zepeda-Palacio, C | 1 |
| Mendoza-Velásquez, C | 1 |
| Camacho-Ordóñez, A | 1 |
| Ortiz Bibriesca, DM | 1 |
| Estrada-Mena, FJ | 1 |
| Martin, BL | 1 |
| Thompson, LC | 1 |
| Kim, YH | 2 |
| Snow, SJ | 1 |
| Schladweiler, MC | 1 |
| Phillips, P | 1 |
| Harmon, M | 1 |
| King, C | 1 |
| Richards, J | 1 |
| George, I | 1 |
| Haykal-Coates, N | 1 |
| Gilmour, MI | 1 |
| Kodavanti, UP | 1 |
| Hazari, MS | 1 |
| Farraj, AK | 1 |
| Shen, Z | 1 |
| Zou, Y | 1 |
| Gao, K | 1 |
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| Wurtzel, JGT | 1 |
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| Goldfinger, LE | 1 |
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| Chen, R | 1 |
| Chen, J | 2 |
| Xun, J | 1 |
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| Steinhart, C | 1 |
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| Gaikwad, S | 1 |
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| Anlay, DZ | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Randomized Controlled Trial of Losartan for Patients With COVID-19 Requiring Hospitalization[NCT04312009] | Phase 2 | 205 participants (Actual) | Interventional | 2020-04-13 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Outcome reported as the number of participants who have expired at 28 days post enrollment. (NCT04312009)
Timeframe: 28 days
| Intervention | proportion of participants (Number) |
|---|---|
| Placebo | 0.087 |
| Losartan | 0.11 |
Outcome reported as the number of participants who have expired at 90 days post enrollment. (NCT04312009)
Timeframe: 90 days
| Intervention | proportion of participants (Number) |
|---|---|
| Placebo | 0.106 |
| Losartan | 0.11 |
Nasopharyngeal swabs will be collected at baseline and day 15. Viral load is measured as number of viral genetic copies per mL. (NCT04312009)
Timeframe: 15 days
| Intervention | log10 copies/mL (Mean) |
|---|---|
| Placebo | -4.2 |
| Losartan | -4.8 |
Outcome reported as the mean number of daily hypotensive episodes (MAP < 65 mmHg) prompting intervention (indicated by a fluid bolus >=500 mL) per participant in each arm. (NCT04312009)
Timeframe: 10 days
| Intervention | episodes per day (Mean) |
|---|---|
| Placebo | 0.048 |
| Losartan | 0.119 |
Outcome calculated from the partial pressure of oxygen or peripheral saturation of oxygen by pulse oximetry divided by the fraction of inspired oxygen (PaO2 or SaO2 : FiO2 ratio). PaO2 is preferentially used if available. A correction is applied for endotracheal intubation and/or positive end-expiratory pressure. Patients discharged prior to day 7 will have a home pulse oximeter send home for measurement of the day 7 value, and will be adjusted for home O2 use, if applicable. Patients who died will be applied a penalty with a P/F ratio of 0. (NCT04312009)
Timeframe: 7 days
| Intervention | ratio (Mean) |
|---|---|
| Placebo | 281.4 |
| Losartan | 260.9 |
Outcome reported as the number of participants in each arm who fall into each of 7 categories. Lower scores indicate greater condition severity. The ordinal scale is an assessment of the clinical status at the first assessment of a given study day. The scale is as follows: 1) Death; 2) Hospitalized, on invasive mechanical ventilation or extracorporeal membrane oxygenation (ECMO); 3) Hospitalized, on non-invasive ventilation or high flow oxygen devices; 4) Hospitalized, requiring supplemental oxygen; 5) Hospitalized, not requiring supplemental oxygen; 6) Not hospitalized, limitation on activities; 7) Not hospitalized, no limitations on activities. (NCT04312009)
Timeframe: 28 days
| Intervention | score (Mean) |
|---|---|
| Placebo | 4.3 |
| Losartan | 4.2 |
Outcome reported as the number of participants in each arm who require admission to the Intensive Care Unit (ICU). (NCT04312009)
Timeframe: 10 days
| Intervention | proportion of participants (Number) |
|---|---|
| Placebo | 0.272 |
| Losartan | 0.36 |
Outcome reported as the mean length of in-patient hospital stay (in days) for participants in each arm. (NCT04312009)
Timeframe: 90 days
| Intervention | days (Median) |
|---|---|
| Placebo | 5.9 |
| Losartan | 7.1 |
Outcome reported as the mean number of days participants in each arm did not require therapeutic oxygen usage during an in-patient hospital admission. (NCT04312009)
Timeframe: 28 days
| Intervention | days (Mean) |
|---|---|
| Placebo | 24.6 |
| Losartan | 23.6 |
Outcome reported as the mean number of days participants in each arm did not require vasopressor usage during an in-patient hospital admission. (NCT04312009)
Timeframe: 10 days
| Intervention | days (Mean) |
|---|---|
| Placebo | 9.4 |
| Losartan | 8.7 |
Outcome reported as the mean number of days participants in each arm did not require mechanical ventilation during an in-patient hospital admission. (NCT04312009)
Timeframe: 28 days
| Intervention | days (Mean) |
|---|---|
| Placebo | 18.4 |
| Losartan | 18.1 |
Oxygen saturation (percent) is measured by pulse oximeter. Fraction of inspired oxygen (FiO2) (unitless) is the volumetric fraction of oxygen to other gases in respiratory support. The S/F ratio is unitless. (NCT04312009)
Timeframe: 7 days
| Intervention | n/a (ratio) (Mean) |
|---|---|
| Placebo | 357.4 |
| Losartan | 331.5 |
"Outcome reported as the number of participants in each arm who experience acute kidney injury as defined by the Kidney Disease Improving Global Outcomes (KDIGO) guidelines:~Increase in serum creatinine by 0.3mg/dL or more within 48 hours OR Increase in serum creatinine to 1.5 times baseline or more within the last 7 days OR Urine output less than 0.5 mL/kg/h for 6 hours." (NCT04312009)
Timeframe: 10 days
| Intervention | proportion of participants (Number) |
|---|---|
| Placebo | 0.106 |
| Losartan | 0.119 |
Outcome reported as the number of participants in each arm requiring the use of vasopressors for hypotension. (NCT04312009)
Timeframe: 10 days
| Intervention | proportion of participants (Number) |
|---|---|
| Placebo | 0.106 |
| Losartan | 0.198 |
2 reviews available for losartan and 2019 Novel Coronavirus Disease
| Article | Year |
|---|---|
Losartan in hospitalized patients with COVID-19 in North America: An individual participant data meta-analysis.
Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Bayes Theorem; COVID-19; | 2023 |
Topics: 3T3-L1 Cells; A Kinase Anchor Proteins; Acetates; Achilles Tendon; Acute Kidney Injury; Acute Pain; | 2022 |
Topics: 3T3-L1 Cells; A Kinase Anchor Proteins; Acetates; Achilles Tendon; Acute Kidney Injury; Acute Pain; | 2022 |
Topics: 3T3-L1 Cells; A Kinase Anchor Proteins; Acetates; Achilles Tendon; Acute Kidney Injury; Acute Pain; | 2022 |
Topics: 3T3-L1 Cells; A Kinase Anchor Proteins; Acetates; Achilles Tendon; Acute Kidney Injury; Acute Pain; | 2022 |
3 trials available for losartan and 2019 Novel Coronavirus Disease
| Article | Year |
|---|---|
Efficacy of Losartan in Hospitalized Patients With COVID-19-Induced Lung Injury: A Randomized Clinical Trial.
Topics: Adult; Aged; Angiotensin II Type 1 Receptor Blockers; COVID-19; COVID-19 Drug Treatment; Double-Blin | 2022 |
Topics: 3T3-L1 Cells; A Kinase Anchor Proteins; Acetates; Achilles Tendon; Acute Kidney Injury; Acute Pain; | 2022 |
Topics: 3T3-L1 Cells; A Kinase Anchor Proteins; Acetates; Achilles Tendon; Acute Kidney Injury; Acute Pain; | 2022 |
Topics: 3T3-L1 Cells; A Kinase Anchor Proteins; Acetates; Achilles Tendon; Acute Kidney Injury; Acute Pain; | 2022 |
Topics: 3T3-L1 Cells; A Kinase Anchor Proteins; Acetates; Achilles Tendon; Acute Kidney Injury; Acute Pain; | 2022 |
Comparison of losartan and amlodipine effects on the outcomes of patient with COVID-19 and primary hypertension: A randomised clinical trial.
Topics: Aged; Aged, 80 and over; Amlodipine; Antihypertensive Agents; Blood Pressure; COVID-19; Double-Blind | 2021 |
17 other studies available for losartan and 2019 Novel Coronavirus Disease
| Article | Year |
|---|---|
Antihypertensive drug treatment and susceptibility to SARS-CoV-2 infection in human PSC-derived cardiomyocytes and primary endothelial cells.
Topics: Antihypertensive Agents; Cells, Cultured; COVID-19; COVID-19 Drug Treatment; Disease Susceptibility; | 2021 |
Correlation of ACE2 with RAS components after Losartan treatment in light of COVID-19.
Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme 2; COVID-19; COVID-19 Drug Treatment | 2021 |
Comment on 'Comparison of losartan and amlodipine effects on the outcomes of patient with COVID-19 and primary hypertension: A randomised clinical trial'.
Topics: Amlodipine; Antihypertensive Agents; COVID-19; Humans; Hypertension; Losartan; SARS-CoV-2 | 2021 |
Does Losartan reduce the severity of COVID-19 in hypertensive patients?
Topics: Antihypertensive Agents; COVID-19; Humans; Hypertension; Losartan; SARS-CoV-2 | 2022 |
All-solid-state paper-based potentiometric combined sensor modified with reduced graphene oxide (rGO) and molecularly imprinted polymer for monitoring losartan drug in pharmaceuticals and biological samples.
Topics: Carbon; COVID-19; Humans; Losartan; Molecularly Imprinted Polymers | 2023 |
Structure-Based Virtual Screening and Functional Validation of Potential Hit Molecules Targeting the SARS-CoV-2 Main Protease.
Topics: Antiviral Agents; Biological Products; Coronavirus 3C Proteases; Coronavirus Protease Inhibitors; CO | 2022 |
COVID-19: Understanding the impact of anti-hypertensive drugs and hydroxychloroquine on the ACE1 and ACE2 in lung and adipose tissue in SHR and WKY rats.
Topics: Adipose Tissue; Angiotensin-Converting Enzyme 2; Animals; Antihypertensive Agents; Blood Pressure; C | 2023 |
Telmisartan and losartan: The marked differences between their chemical and pharmacological properties may explain the difference in therapeutic efficacy in hospitalized patients with COVID-19.
Topics: Antihypertensive Agents; COVID-19; Humans; Hypertension; Losartan; Telmisartan | 2023 |
Perindopril and losartan attenuate pro-coagulation factors in human adipocytes exposed to SARS-CoV-2 spike protein.
Topics: Adipocytes; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme 2; Angiotensin-Convertin | 2023 |
Facts and reflections on COVID-19 and anti-hypertensives drugs.
Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inh | 2020 |
A potential protective role of losartan against coronavirus-induced lung damage.
Topics: Angiotensin II Type 1 Receptor Blockers; Betacoronavirus; Coronavirus Infections; COVID-19; Humans; | 2020 |
COVID-19 and Renin Angiotensin Blockers: Current Evidence and Recommendations.
Topics: Angiotensin Receptor Antagonists; Animals; Betacoronavirus; Coronavirus Infections; COVID-19; Diseas | 2020 |
Effect of angiotensin II blockers on the prognosis of COVID-19: a toxicological view.
Topics: Angiotensin-Converting Enzyme Inhibitors; Antiviral Agents; Betacoronavirus; Coronavirus Infections; | 2020 |
Effects of Renin-Angiotensin Inhibition on ACE2 (Angiotensin-Converting Enzyme 2) and TMPRSS2 (Transmembrane Protease Serine 2) Expression: Insights Into COVID-19.
Topics: Angiotensin II Type 2 Receptor Blockers; Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enz | 2020 |
Safety, tolerability, and outcomes of losartan use in patients hospitalized with SARS-CoV-2 infection: A feasibility study.
Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Blood Pressure; COVID-19; Female; Humans; Hypertensio | 2020 |
A pressor dose of angiotensin II has no influence on the angiotensin-converting enzyme 2 and other molecules associated with SARS-CoV-2 infection in mice.
Topics: ADAM17 Protein; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzy | 2021 |
COVID and the brain: researchers zero in on how damage occurs.
Topics: Animals; Antibodies, Viral; Astrocytes; Autoantibodies; Autopsy; Brain; Capillaries; COVID-19; Crice | 2021 |