Page last updated: 2024-10-30

lorglumide and Body Weight

lorglumide has been researched along with Body Weight in 12 studies

lorglumide: RN given refers to (+-)-isomer
lorglumide : A racemate comprising equal amounts of (R)- and (S)-lorglumide.
N(2)-(3,4-dichlorobenzoyl)-N,N-dipentyl-alpha-glutamine : A dicarboxylic acid monoamide obtained by formal condensation of the alpha-carboxy group of N-(3,4-dichlorobenzoyl)glutamic acid with the amino group of dipentylamine.

Body Weight: The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.

Research Excerpts

ExcerptRelevanceReference
"Pretreatment with lorglumide blocked the reducing effect of P."1.35Reducing effect of a Phaseolus vulgaris dry extract on food intake, body weight, and glycemia in rats. ( Bombardelli, E; Cabras, C; Carai, MA; Colombo, G; Donzelli, F; Fantini, N; Gessa, GL; Lobina, C; Morazzoni, P; Riva, A, 2009)
"The incidence of pancreatic cancer appeared significantly (P < 0."1.29Effect of cholecystokinin analogue caerulein and cholecystokinin antagonist lorglumide on pancreatic carcinogenesis in the rat. ( Alaggio, R; Behboo, R; Khajeturian, E; Militello, C; Pedrazzoli, S; Perasole, A; Rovati, L; Sperti, C, 1994)
"Rats treated with cholecystokinin developed more acidophilic atypical acinar cell nodules, adenomas and adenocarcinomas than control animals."1.28Role of cholecystokinin in dietary fat-promoted azaserine-induced pancreatic carcinogenesis in rats. ( Appel, MJ; Jansen, JB; Lamers, CB; Meijers, M; Rovati, LC; Sprij-Mooij, D; Van Garderen-Hoetmer, A; Woutersen, RA, 1992)
"Lorglumide was given 15 min before caerulein."1.28Effect of lorglumide (CR-1409) on pancreatic secretory and trophic response to caerulein in newborn rats. ( Folly, G; Papp, M; Varga, G, 1991)
"Cholecystokinin (CCK) has been shown to promote pancreatic growth and azaserine-induced pancreatic carcinogenesis in rats."1.28Role of cholecystokinin in the development of BOP-induced pancreatic lesions in hamsters. ( Jansen, JB; Lamers, CB; Meijers, M; Rovati, LC; van Garderen-Hoetmer, A; Woutersen, RA, 1990)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19903 (25.00)18.7374
1990's7 (58.33)18.2507
2000's2 (16.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fantini, N1
Cabras, C1
Lobina, C1
Colombo, G1
Gessa, GL1
Riva, A1
Donzelli, F1
Morazzoni, P1
Bombardelli, E1
Carai, MA1
Pu, HF1
Huang, WJ1
Tseng, WM1
Wang, SW1
Liu, YW1
Doong, ML1
Wang, PS1
Evrard, S1
Hoeltzel, A1
Aprahamian, M1
Bernard, C1
Mutter, D1
Marescaux, J1
Damgé, C1
Sperti, C1
Militello, C1
Rovati, L1
Behboo, R1
Khajeturian, E1
Perasole, A1
Alaggio, R1
Pedrazzoli, S1
Watanapa, P1
Flaks, B1
Oztas, H1
Deprez, PH1
Calam, J1
Williamson, RC1
Appel, MJ1
Meijers, M3
Van Garderen-Hoetmer, A3
Lamers, CB4
Rovati, LC4
Sprij-Mooij, D1
Jansen, JB4
Woutersen, RA4
Papp, M3
Varga, G3
Folly, G1
Scarpignato, C2
Dobronyi, I1
Douglas, BR1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Randomized Controlled Trial to Evaluate the Effects of Repeated Periods of Modified Fasting to Support Healthy Natural Weight Management and Prevention of Weight Gain in Overweight But Generally Healthy Adults Over the Winter Holiday Period[NCT03372109]23 participants (Actual)Interventional2017-11-14Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

12 other studies available for lorglumide and Body Weight

ArticleYear
Reducing effect of a Phaseolus vulgaris dry extract on food intake, body weight, and glycemia in rats.
    Journal of agricultural and food chemistry, 2009, Oct-14, Volume: 57, Issue:19

    Topics: alpha-Amylases; Animals; Blood Glucose; Body Weight; Cholecystokinin; Drug Interactions; Eating; Ene

2009
Effects of juice from Morinda citrifolia (Noni) on gastric emptying in male rats.
    The Chinese journal of physiology, 2004, Dec-31, Volume: 47, Issue:4

    Topics: Animals; Beverages; Body Weight; Cholecystokinin; Drinking; Eating; Gastric Emptying; Gastrointestin

2004
Implication of cholecystokinin in pancreatic adaptation after biliopancreatic bypass in the rat.
    Digestion, 1994, Volume: 55, Issue:4

    Topics: Adaptation, Physiological; Animals; Biliopancreatic Diversion; Body Weight; Cholecystokinin; Data In

1994
Effect of cholecystokinin analogue caerulein and cholecystokinin antagonist lorglumide on pancreatic carcinogenesis in the rat.
    Journal of surgical oncology, 1994, Volume: 57, Issue:1

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Body Weight; Ceruletide; Chi-Square Distr

1994
Inhibitory effect of a cholecystokinin antagonist on pancreatic carcinogenesis after pancreatobiliary diversion.
    British journal of cancer, 1993, Volume: 67, Issue:4

    Topics: Animals; Azaserine; Biliopancreatic Diversion; Body Weight; Cholecystokinin; Cocarcinogenesis; Male;

1993
Role of cholecystokinin in dietary fat-promoted azaserine-induced pancreatic carcinogenesis in rats.
    British journal of cancer, 1992, Volume: 66, Issue:1

    Topics: Animals; Azaserine; Body Weight; Cholecystokinin; Dietary Fats; Liver; Male; Organ Size; Pancreas; P

1992
Effect of lorglumide (CR-1409) on pancreatic secretory and trophic response to caerulein in newborn rats.
    Acta physiologica Hungarica, 1991, Volume: 78, Issue:1

    Topics: Amylases; Animals; Animals, Newborn; Body Weight; Ceruletide; Cholecystokinin; Corticosterone; Femal

1991
Effects of bombesin on the development of N-nitrosobis(2-oxopropyl)amine-induced pancreatic lesions in hamsters.
    Cancer letters, 1991, Jul-26, Volume: 59, Issue:1

    Topics: Animals; Body Weight; Bombesin; Cholecystokinin; Cricetinae; Liver; Male; Mesocricetus; Nitrosamines

1991
Role of cholecystokinin in the development of BOP-induced pancreatic lesions in hamsters.
    Carcinogenesis, 1990, Volume: 11, Issue:12

    Topics: Animals; Body Weight; Carcinogens; Cholecystokinin; Cocarcinogenesis; Cricetinae; Male; Nitrosamines

1990
Effect of a new potent CCK antagonist, lorglumide, on caerulein- and bombesin-induced pancreatic secretion and growth in the rat.
    British journal of pharmacology, 1989, Volume: 96, Issue:3

    Topics: Amylases; Anesthesia; Animals; Body Weight; Bombesin; Ceruletide; Cholecystokinin; DNA; Glutamine; I

1989
Pancreatic secretory and trophic response to caerulein in rats: effect of proglumide and lorglumide.
    Fundamental & clinical pharmacology, 1989, Volume: 3, Issue:3

    Topics: Amylases; Animals; Body Weight; Ceruletide; DNA; Glutamine; In Vitro Techniques; Organ Size; Pancrea

1989
Study into the role of cholecystokinin in bombesin-stimulated pancreatic growth in rats and hamsters.
    European journal of pharmacology, 1989, Feb-28, Volume: 161, Issue:2-3

    Topics: Animals; Body Weight; Bombesin; Cholecystokinin; Cricetinae; DNA; Male; Mesocricetus; Pancreas; Prog

1989