lorcaserin has been researched along with Bulimia* in 2 studies
1 trial(s) available for lorcaserin and Bulimia
| Article | Year |
|---|---|
A randomized controlled trial of lorcaserin and lifestyle counselling for weight loss maintenance: changes in emotion- and stress-related eating, food cravings and appetite.
Anti-obesity medication may help people maintain diet-induced reductions in appetite. The present exploratory analysis assessed the effects of lorcaserin on changes at 24 weeks post-randomization in emotion- and stress-related eating, food cravings and other measures of appetite (i.e. binge eating, cognitive restraint, disinhibition, hunger, preoccupation with eating and fullness). The parent study investigated the efficacy of combined lorcaserin and behavioural treatment in facilitating weight loss maintenance (WLM) in 137 adults (mean age = 46.1 years, 86.1% female, 68.6% black) who had lost ≥5% of initial weight during a 14-week, low-calorie diet (LCD) run-in. Participants were randomly assigned to lorcaserin or placebo and were provided with group WLM counselling sessions. Emotion- and stress-related eating, food cravings and appetite were measured at the start of the LCD (week -14), randomization (0) and week 24. From randomization, lorcaserin-treated participants had significantly greater improvements in emotion- and stress-related eating compared to placebo-treated participants (P = 0.04). However, groups did not differ significantly after randomization in changes in the frequency of food cravings, binge eating or other measures of appetite (Ps > 0.05). Compared to placebo, lorcaserin may improve emotion- and stress-related eating. Topics: Adult; Appetite; Behavior Therapy; Benzazepines; Bulimia; Counseling; Craving; Eating; Emotions; Female; Humans; Life Style; Male; Middle Aged; Obesity; Placebos; Stress, Psychological; Treatment Outcome; Weight Loss | 2018 |
1 other study(ies) available for lorcaserin and Bulimia
| Article | Year |
|---|---|
Activation of Serotonin 2C Receptors in Dopamine Neurons Inhibits Binge-like Eating in Mice.
Neural networks that regulate binge eating remain to be identified, and effective treatments for binge eating are limited.. We combined neuroanatomic, pharmacologic, electrophysiological, Cre-lox, and chemogenetic approaches to investigate the functions of 5-hydroxytryptamine (5-HT) 2C receptor (5-HT. We showed that 5-HT stimulates DA neural activity through a 5-HT. We identified the 5-HT Topics: Animals; Benzazepines; Bulimia; Dopaminergic Neurons; Eating; Female; Fluoxetine; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Receptor, Serotonin, 5-HT2C; Selective Serotonin Reuptake Inhibitors; Ventral Tegmental Area | 2017 |