Page last updated: 2024-10-30

lorazepam and Serotonin Syndrome

lorazepam has been researched along with Serotonin Syndrome in 9 studies

Lorazepam: A benzodiazepine used as an anti-anxiety agent with few side effects. It also has hypnotic, anticonvulsant, and considerable sedative properties and has been proposed as a preanesthetic agent.

Serotonin Syndrome: An adverse drug interaction characterized by altered mental status, autonomic dysfunction, and neuromuscular abnormalities. It is most frequently caused by use of both serotonin reuptake inhibitors and monoamine oxidase inhibitors, leading to excess serotonin availability in the CNS at the serotonin 1A receptor.

Research Excerpts

ExcerptRelevanceReference
"A young male with schizophrenia, dependence syndrome (multiple drug use) and a severe depressive episode develops a serotonin syndrome with Sertraline and Ziprasidone."7.85[Psychosis, Intoxication or Serotonin Syndrome? - A 20-Year Old Male with Ziprasidone und Sertraline]. ( Grabe, HJ; Janowitz, D; Schomerus, G; Speerforck, S, 2017)
"Serotonin syndrome is a potentially life-threatening condition associated with increased serotonergic activity in the central nervous system."6.72Postoperative Serotonin Syndrome Following Methylene Blue Administration for Vasoplegia After Cardiac Surgery: A Case Report and Review of the Literature. ( Basta, MN, 2021)
"A young male with schizophrenia, dependence syndrome (multiple drug use) and a severe depressive episode develops a serotonin syndrome with Sertraline and Ziprasidone."3.85[Psychosis, Intoxication or Serotonin Syndrome? - A 20-Year Old Male with Ziprasidone und Sertraline]. ( Grabe, HJ; Janowitz, D; Schomerus, G; Speerforck, S, 2017)
"A 6-year-old girl displayed symptoms of serotonin syndrome after accidental ingestion of Vyvanse (lisdexamfetamine dimesylate)."3.78Dexmedetomidine to treat lisdexamfetamine overdose and serotonin toxidrome in a 6-year-old girl. ( Akingbola, OA; Singh, D, 2012)
"Serotonin syndrome is a potentially life-threatening condition associated with increased serotonergic activity in the central nervous system."2.72Postoperative Serotonin Syndrome Following Methylene Blue Administration for Vasoplegia After Cardiac Surgery: A Case Report and Review of the Literature. ( Basta, MN, 2021)
"In the first, catatonia was described as an under-recognized syndrome with a potentially fatal outcome."2.40Catatonia. 2: Diagnosis, management and prognosis. ( Clark, T; Rickards, H, 1999)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (11.11)18.2507
2000's3 (33.33)29.6817
2010's3 (33.33)24.3611
2020's2 (22.22)2.80

Authors

AuthorsStudies
Duignan, KM1
Quinn, AM1
Matson, AM1
Basta, MN1
Laliberte, B1
Kishk, OA1
Speerforck, S1
Janowitz, D1
Schomerus, G1
Grabe, HJ1
Frank, C1
Brantley, E1
Cohn, J1
Babu, K1
Akingbola, OA1
Singh, D1
Dimellis, D1
Clark, T1
Rickards, H1

Reviews

2 reviews available for lorazepam and Serotonin Syndrome

ArticleYear
Postoperative Serotonin Syndrome Following Methylene Blue Administration for Vasoplegia After Cardiac Surgery: A Case Report and Review of the Literature.
    Seminars in cardiothoracic and vascular anesthesia, 2021, Volume: 25, Issue:1

    Topics: Cardiac Surgical Procedures; Cyproheptadine; Enzyme Inhibitors; Humans; Hypnotics and Sedatives; Lor

2021
Catatonia. 2: Diagnosis, management and prognosis.
    Hospital medicine (London, England : 1998), 1999, Volume: 60, Issue:11

    Topics: Benzodiazepines; Catatonia; Diagnosis, Differential; Electroconvulsive Therapy; Humans; Hypnotics an

1999

Other Studies

7 other studies available for lorazepam and Serotonin Syndrome

ArticleYear
Serotonin syndrome from sertraline monotherapy.
    The American journal of emergency medicine, 2020, Volume: 38, Issue:8

    Topics: Adult; Anti-Anxiety Agents; Anxiety; Humans; Lorazepam; Male; Selective Serotonin Reuptake Inhibitor

2020
Serotonin Syndrome in a Pediatric Patient After Vilazodone Ingestion.
    Pediatric emergency care, 2018, Volume: 34, Issue:12

    Topics: Anticonvulsants; Eating; Humans; Infant; Lorazepam; Selective Serotonin Reuptake Inhibitors; Seroton

2018
[Psychosis, Intoxication or Serotonin Syndrome? - A 20-Year Old Male with Ziprasidone und Sertraline].
    Psychiatrische Praxis, 2017, Volume: 44, Issue:8

    Topics: Depressive Disorder, Major; Dose-Response Relationship, Drug; Drug Therapy, Combination; Humans; Lor

2017
Recognition and treatment of serotonin syndrome.
    Canadian family physician Medecin de famille canadien, 2008, Volume: 54, Issue:7

    Topics: Aged, 80 and over; Anticonvulsants; Depressive Disorder; Drug Interactions; Humans; Lorazepam; Male;

2008
Case files of the program in medical toxicology at brown university: amantadine withdrawal and the neuroleptic malignant syndrome.
    Journal of medical toxicology : official journal of the American College of Medical Toxicology, 2009, Volume: 5, Issue:2

    Topics: Amantadine; Antipsychotic Agents; Diagnosis, Differential; Drug Therapy, Combination; Female; Fluid

2009
Dexmedetomidine to treat lisdexamfetamine overdose and serotonin toxidrome in a 6-year-old girl.
    American journal of critical care : an official publication, American Association of Critical-Care Nurses, 2012, Volume: 21, Issue:6

    Topics: Adrenergic alpha-2 Receptor Agonists; Anti-Anxiety Agents; Central Nervous System Stimulants; Child;

2012
Serotonin syndrome produced by a combination of venlafaxine and mirtazapine.
    The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry, 2002, Volume: 3, Issue:3

    Topics: Adrenergic beta-Antagonists; Adult; Antidepressive Agents, Tricyclic; Cyclohexanols; Drug Therapy, C

2002