lorazepam has been researched along with Psychotic Disorders in 82 studies
Lorazepam: A benzodiazepine used as an anti-anxiety agent with few side effects. It also has hypnotic, anticonvulsant, and considerable sedative properties and has been proposed as a preanesthetic agent.
Psychotic Disorders: Disorders in which there is a loss of ego boundaries or a gross impairment in reality testing with delusions or prominent hallucinations. (From DSM-IV, 1994)
| Excerpt | Relevance | Reference |
|---|---|---|
| " Acutely agitated patients with schizophrenia or schizoaffective disorder (n = 67) were randomized to receive 10 mg IM olanzapine (n = 37) or 5 mg IM haloperidol plus 2 mg IM lorazepam (n = 30)." | 9.20 | Intramuscular olanzapine versus intramuscular haloperidol plus lorazepam for the treatment of acute schizophrenia with agitation: An open-label, randomized controlled trial. ( Chen, HH; Chen, YH; Hsieh, MH; Huang, CL; Huang, GH; Hwang, TJ; Hwu, HG, 2015) |
| " The authors compared the efficacy and tolerability of ziprasidone and olanzapine in the treatment of acutely ill inpatients with schizophrenia or schizoaffective disorder." | 9.11 | Randomized, controlled, double-blind multicenter comparison of the efficacy and tolerability of ziprasidone and olanzapine in acutely ill inpatients with schizophrenia or schizoaffective disorder. ( Glick, ID; Romano, SJ; Simpson, GM; Siu, CO; Weiden, PJ, 2004) |
| "To examine whether haloperidol plus promethazine is an effective treatment for psychosis-induced aggression." | 8.93 | Haloperidol plus promethazine for psychosis-induced aggression. ( Alexander, J; Allen, MH; Gandhi, P; Huf, G, 2016) |
| "To investigate whether haloperidol alone, administered orally, intramuscularly or intravenously, is effective treatment for psychosis-induced agitation or aggression." | 8.88 | Haloperidol for psychosis-induced aggression or agitation (rapid tranquillisation). ( Adams, CE; Jones, H; Powney, MJ, 2012) |
| "To examine whether haloperidol plus promethazine is an effective treatment for psychosis induced agitation/aggression." | 8.85 | Haloperidol plus promethazine for psychosis-induced aggression. ( Alexander, J; Allen, MH; Huf, G; Raveendran, NS, 2009) |
| "To examine whether haloperidol plus promethazine is an effective treatment for psychosis induced agitation/aggression." | 8.82 | Haloperidol plus promethazine for psychosis induced aggression. ( Alexander, J; Allen, MH; Huf, G, 2005) |
| " The patient was diagnosed with catatonia due to benzodiazepine withdrawal and had gradual return to baseline with administration of lorazepam 1 mg intravenous three times per day." | 7.88 | Catatonia due to alprazolam withdrawal. ( Abdelmalak, F; Bornmann, C; Iyengar, S; LaRocca, T, 2018) |
| "The resurgence of catatonia following tapering of lorazepam is a common clinical phenomenon." | 7.85 | Resurgence of catatonia following tapering or stoppage of lorazepam - A case series and implications. ( Ali, SF; Gowda, GS; Jaisoorya, TS; Math, SB, 2017) |
| "The authors report five new cases of catatonia; three patients responded favorably and two failed to respond to lorazepam." | 6.37 | Lorazepam treatment of psychogenic catatonia: an update. ( Kilzieh, N; Salam, SA, 1988) |
| "Bush-Francis Catatonia Rating Scale score was 27." | 5.72 | Baclofen and catatonia: a case report. ( Caprara, ALF; Gadamidi, VK; Konduru, SN; Rissardo, JP, 2022) |
| " Acutely agitated patients with schizophrenia or schizoaffective disorder (n = 67) were randomized to receive 10 mg IM olanzapine (n = 37) or 5 mg IM haloperidol plus 2 mg IM lorazepam (n = 30)." | 5.20 | Intramuscular olanzapine versus intramuscular haloperidol plus lorazepam for the treatment of acute schizophrenia with agitation: An open-label, randomized controlled trial. ( Chen, HH; Chen, YH; Hsieh, MH; Huang, CL; Huang, GH; Hwang, TJ; Hwu, HG, 2015) |
| " The authors compared the efficacy and tolerability of ziprasidone and olanzapine in the treatment of acutely ill inpatients with schizophrenia or schizoaffective disorder." | 5.11 | Randomized, controlled, double-blind multicenter comparison of the efficacy and tolerability of ziprasidone and olanzapine in acutely ill inpatients with schizophrenia or schizoaffective disorder. ( Glick, ID; Romano, SJ; Simpson, GM; Siu, CO; Weiden, PJ, 2004) |
| "In a double-blind, prospective study, 2 mg of intramuscular lorazepam and 5 mg of intramuscular haloperidol were equally effective in controlling aggression, agitation, and assaultive behavior." | 5.07 | Parenteral lorazepam versus parenteral haloperidol for the control of psychotic disruptive behavior. ( Flowers, E; Glassman, R; Miyawaki, E; Rood, L; Salzman, C; Solomon, D; Thayer, S, 1991) |
| "To examine whether haloperidol plus promethazine is an effective treatment for psychosis-induced aggression." | 4.93 | Haloperidol plus promethazine for psychosis-induced aggression. ( Alexander, J; Allen, MH; Gandhi, P; Huf, G, 2016) |
| "To investigate whether haloperidol alone, administered orally, intramuscularly or intravenously, is effective treatment for psychosis-induced agitation or aggression." | 4.88 | Haloperidol for psychosis-induced aggression or agitation (rapid tranquillisation). ( Adams, CE; Jones, H; Powney, MJ, 2012) |
| "Haloperidol in combination with promethazine, and olanzapine, are effective in psychotic agitation, although haloperidol plus promethazine has a more rapid onset of effect faster; lorazepam is effective in non-psychotic agitation, aggression or excitement as well as in acute agitation of unknown origin." | 4.87 | [Rapid tranquillisation; review of the literature and recommendations]. ( Bak, M; Marcelis, M; van Os, J, 2011) |
| "To examine whether haloperidol plus promethazine is an effective treatment for psychosis induced agitation/aggression." | 4.85 | Haloperidol plus promethazine for psychosis-induced aggression. ( Alexander, J; Allen, MH; Huf, G; Raveendran, NS, 2009) |
| "To examine whether haloperidol plus promethazine is an effective treatment for psychosis induced agitation/aggression." | 4.82 | Haloperidol plus promethazine for psychosis induced aggression. ( Alexander, J; Allen, MH; Huf, G, 2005) |
| "Neuroleptic-induced catatonia is reported in an adolescent patient who responded successfully to lorazepam." | 4.78 | Neuroleptic-induced catatonia as a stage in the progression toward neuroleptic malignant syndrome. ( Woodbury, MA; Woodbury, MM, 1992) |
| " The patient was diagnosed with catatonia due to benzodiazepine withdrawal and had gradual return to baseline with administration of lorazepam 1 mg intravenous three times per day." | 3.88 | Catatonia due to alprazolam withdrawal. ( Abdelmalak, F; Bornmann, C; Iyengar, S; LaRocca, T, 2018) |
| "The resurgence of catatonia following tapering of lorazepam is a common clinical phenomenon." | 3.85 | Resurgence of catatonia following tapering or stoppage of lorazepam - A case series and implications. ( Ali, SF; Gowda, GS; Jaisoorya, TS; Math, SB, 2017) |
| " The syndrome resolved within a few days of stopping haloperidol and initiation of lorazepam." | 3.78 | Neuroleptic-induced catatonia in two hospitalized patients. ( Gugger, JJ; Saad, M; Smith, C, 2012) |
| "Lorazepam was administered to all of the patients assigned to risperidone and to 89% of those assigned to zuclopenthixol." | 2.71 | Oral risperidone with lorazepam versus oral zuclopenthixol with lorazepam in the treatment of acute psychosis in emergency psychiatry: a prospective, comparative, open-label study. ( Dries, PJ; Hovens, JE; Loonen, AJ; Melman, CT; Wapenaar, RJ, 2005) |
| "The drop in the akathisia score from a pretreatment value of 1." | 2.66 | Treatment of akathisia with lorazepam. An open clinical trial. ( Bartels, M; Heide, K; Mann, K; Schied, HW, 1987) |
| "When haloperidol and midazolam were compared with olanzapine, there was some evidence the combination was superior in terms of improvement, sedation and behaviour." | 2.49 | Benzodiazepines for psychosis-induced aggression or agitation. ( Beck, A; Gillies, D; Rathbone, J; Sampson, S, 2013) |
| "Catatonia is often a prominent feature of the syndrome." | 2.49 | Delirious mania: detection, diagnosis, and clinical management in the acute setting. ( Bobo, WV; Heckers, S; Jacobowski, NL, 2013) |
| "To estimate the effects of benzodiazepines, alone or in combination with antipsychotics, when compared to placebo or antipsychotics, to control disturbed behaviour and reduce psychotic symptoms." | 2.43 | Benzodiazepines alone or in combination with antipsychotic drugs for acute psychosis. ( Beck, A; Gillies, D; McCloud, A; Rathbone, J, 2005) |
| "The authors report five new cases of catatonia; three patients responded favorably and two failed to respond to lorazepam." | 2.37 | Lorazepam treatment of psychogenic catatonia: an update. ( Kilzieh, N; Salam, SA, 1988) |
| "Bush-Francis Catatonia Rating Scale score was 27." | 1.72 | Baclofen and catatonia: a case report. ( Caprara, ALF; Gadamidi, VK; Konduru, SN; Rissardo, JP, 2022) |
| " These patients require close monitoring for adverse effects with adjustment of dosing to ensure the optimal balance of risk versus benefit while the patient is acutely psychotic." | 1.43 | Polysubstance-induced relapse of schizoaffective disorder refractory to high-dose antipsychotic medications: a case report. ( Harvey, R; Kekulawala, S; Kent, M; Mostafa, S; Tucker, MG, 2016) |
| "Studies in major depressive disorder have demonstrated that suprathreshold, nondominant (right) hemisphere, unilateral electrode placement ECT has fewer adverse effects, especially cognitive adverse effects, than bitemporal ECT." | 1.40 | Successful use of right unilateral ECT for catatonia: a case series. ( Conway, C; Cristancho, P; Jewkes, D; Mon, T, 2014) |
| "Catatonia is a well-described neuropsychiatric syndrome that has been the subject of several texts." | 1.37 | Cases of catatonia on an academic electroconvulsive therapy service: lessons to learn. ( Aloysi, AS; Kellner, CH; Popeo, DM, 2011) |
| "We describe an unusual presentation of catatonia in a female patient with schizoaffective disorder." | 1.37 | An unusual presentation of catatonia in a patient with schizoaffective disorder. ( Liang, CS; Liao, WC; Yang, FW, 2011) |
| "We recommend being alert for catatonia in patients with or without a psychiatric disorder." | 1.36 | [Catatonia]. ( Blom, JD; Bruijn, DJ, 2010) |
| "Oral treatment with risperidone and lorazepam appears to be a tolerable and comparable alternative to intramuscular haloperidol and lorazepam for short-term treatment of agitated psychosis in patients who accept oral medications." | 1.31 | Risperidone liquid concentrate and oral lorazepam versus intramuscular haloperidol and intramuscular lorazepam for treatment of psychotic agitation. ( Currier, GW; Simpson, GM, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (13.41) | 18.7374 |
| 1990's | 7 (8.54) | 18.2507 |
| 2000's | 22 (26.83) | 29.6817 |
| 2010's | 33 (40.24) | 24.3611 |
| 2020's | 9 (10.98) | 2.80 |
| Authors | Studies |
|---|---|
| Kompella, S | 1 |
| Gallucci, F | 1 |
| Jones, S | 1 |
| Ikekwere, J | 1 |
| Poulsen, R | 1 |
| Parker, J | 1 |
| Coffey, BJ | 2 |
| Stetson, SR | 1 |
| Osser, DN | 1 |
| Rissardo, JP | 1 |
| Konduru, SN | 1 |
| Gadamidi, VK | 1 |
| Caprara, ALF | 1 |
| Garel, N | 1 |
| Joober, R | 1 |
| Herrera-Huerta, CA | 1 |
| Hernández-Salas, LP | 1 |
| Magallanes-Cano, EM | 1 |
| Miller, M | 1 |
| Barbe, N | 1 |
| Poulsen, RJ | 1 |
| Jaworowski, S | 1 |
| Weiser, M | 1 |
| Gropp, C | 1 |
| Malka, M | 1 |
| Haddad, PM | 1 |
| Al Abdulla, M | 1 |
| Latoo, J | 1 |
| Iqbal, Y | 1 |
| Marouda, K | 1 |
| Mantonakis, L | 1 |
| Kollias, K | 1 |
| de Neeling, M | 1 |
| van Paesschen, W | 1 |
| Parks, KA | 1 |
| Parks, CG | 1 |
| Onwuameze, OE | 1 |
| Shrestha, S | 1 |
| Ali, SF | 1 |
| Gowda, GS | 1 |
| Jaisoorya, TS | 1 |
| Math, SB | 1 |
| Agrawal, AK | 1 |
| Das, S | 1 |
| Prakash, R | 1 |
| Aggarwal, N | 1 |
| Kataria, D | 1 |
| Prasad, S | 1 |
| Iyengar, S | 1 |
| Bornmann, C | 1 |
| Abdelmalak, F | 1 |
| LaRocca, T | 1 |
| Bak, M | 2 |
| Weltens, I | 1 |
| Bervoets, C | 1 |
| De Fruyt, J | 1 |
| Samochowiec, J | 1 |
| Fiorillo, A | 1 |
| Sampogna, G | 1 |
| Bienkowski, P | 1 |
| Preuss, WU | 1 |
| Misiak, B | 1 |
| Frydecka, D | 1 |
| Samochowiec, A | 1 |
| Bak, E | 1 |
| Drukker, M | 1 |
| Dom, G | 1 |
| Bhojani, S | 1 |
| Aldana-Bernier, L | 1 |
| Sikder, M | 1 |
| Pawelzik, T | 1 |
| Gillies, D | 3 |
| Sampson, S | 1 |
| Beck, A | 2 |
| Rathbone, J | 2 |
| Cristancho, P | 1 |
| Jewkes, D | 1 |
| Mon, T | 1 |
| Conway, C | 1 |
| Taylor, SF | 1 |
| Demeter, E | 1 |
| Phan, KL | 1 |
| Tso, IF | 1 |
| Welsh, RC | 1 |
| Scharfetter, J | 1 |
| Fischer, P | 1 |
| Verma, R | 1 |
| Junewar, V | 1 |
| Rathaur, BP | 1 |
| Ungvari, GS | 2 |
| Huang, CL | 1 |
| Hwang, TJ | 1 |
| Chen, YH | 1 |
| Huang, GH | 1 |
| Hsieh, MH | 1 |
| Chen, HH | 1 |
| Hwu, HG | 1 |
| van der Markt, A | 1 |
| Heller, HM | 1 |
| van Exel, E | 1 |
| Koychev, I | 1 |
| Hadjiphilippou, S | 1 |
| Lynch, J | 1 |
| Whelan, P | 1 |
| MacCabe, J | 1 |
| Tucker, MG | 1 |
| Kekulawala, S | 1 |
| Kent, M | 1 |
| Mostafa, S | 1 |
| Harvey, R | 1 |
| Huf, G | 3 |
| Alexander, J | 3 |
| Gandhi, P | 1 |
| Allen, MH | 3 |
| Massengale, J | 1 |
| Tafti, BA | 1 |
| Large, L | 1 |
| Skirboll, S | 1 |
| Raveendran, NS | 1 |
| Miller, MA | 1 |
| Kummerow, AM | 1 |
| Mgutshini, T | 1 |
| Krähenmann, R | 1 |
| Küchenhoff, B | 1 |
| Böker, H | 1 |
| Schick, M | 1 |
| Bruijn, DJ | 1 |
| Blom, JD | 1 |
| Binbay, T | 1 |
| Danivas, V | 1 |
| Behere, RV | 1 |
| Varambally, S | 1 |
| Rao, NP | 1 |
| Venkatasubramanian, G | 1 |
| Gangadhar, BN | 1 |
| Aloysi, AS | 1 |
| Popeo, DM | 1 |
| Kellner, CH | 1 |
| Liang, CS | 1 |
| Yang, FW | 1 |
| Liao, WC | 1 |
| van Os, J | 1 |
| Marcelis, M | 1 |
| Gugger, JJ | 1 |
| Saad, M | 1 |
| Smith, C | 1 |
| Coffey, MJ | 1 |
| Thornton, SL | 1 |
| Gerona, RR | 1 |
| Tomaszewski, CA | 1 |
| Powney, MJ | 1 |
| Adams, CE | 1 |
| Jones, H | 1 |
| Uz, Y | 1 |
| Hariri, A | 1 |
| Ünübol, H | 1 |
| Bilici, M | 1 |
| Jacobowski, NL | 1 |
| Heckers, S | 1 |
| Bobo, WV | 1 |
| Lai, JY | 1 |
| Huang, TL | 1 |
| Ziegenbein, M | 1 |
| Kropp, S | 1 |
| Lejeune, J | 1 |
| Larmo, I | 1 |
| Chrzanowski, W | 1 |
| Witte, R | 1 |
| Karavatos, A | 1 |
| Schreiner, A | 1 |
| Lex, A | 1 |
| Medori, R | 2 |
| Simpson, GM | 4 |
| Glick, ID | 1 |
| Weiden, PJ | 1 |
| Romano, SJ | 1 |
| Siu, CO | 1 |
| Jung, IK | 1 |
| Lee, HJ | 1 |
| Cho, BH | 1 |
| Hovens, JE | 1 |
| Dries, PJ | 1 |
| Melman, CT | 1 |
| Wapenaar, RJ | 1 |
| Loonen, AJ | 1 |
| Crockford, D | 1 |
| Belgamwar, RB | 1 |
| Fenton, M | 1 |
| Huffman, JC | 1 |
| Fricchione, GL | 1 |
| Mendhekar, DN | 1 |
| Jiloha, RC | 1 |
| McCloud, A | 1 |
| Pruett, JR | 1 |
| Rizvi, ST | 1 |
| Reimer, J | 1 |
| Aderhold, V | 1 |
| Lambert, M | 1 |
| Haasen, C | 1 |
| Srihari, VH | 1 |
| Lee, TS | 1 |
| Rohrbaugh, RM | 1 |
| D'Souza, DC | 1 |
| Hug, BL | 1 |
| Emsley, R | 1 |
| Koen, L | 1 |
| Oosthuizen, PP | 1 |
| Niehaus, DJ | 1 |
| Rabinowitz, J | 1 |
| Fouks, L | 1 |
| Hertrich, O | 1 |
| Marneros, A | 1 |
| Jäger, A | 1 |
| Battaglia, J | 2 |
| Moss, S | 1 |
| Rush, J | 1 |
| Kang, J | 1 |
| Mendoza, R | 1 |
| Leedom, L | 1 |
| Dubin, W | 1 |
| McGlynn, C | 1 |
| Goodman, L | 1 |
| Foster, S | 1 |
| Kessel, J | 1 |
| Berman, ME | 1 |
| Hillard, JR | 1 |
| Hughes, DH | 1 |
| Geffen, J | 1 |
| Tsoh, JM | 1 |
| Leung, HC | 1 |
| Lee, DT | 1 |
| Currier, GW | 1 |
| Woodbury, MM | 1 |
| Woodbury, MA | 1 |
| Salzman, C | 2 |
| Solomon, D | 1 |
| Miyawaki, E | 1 |
| Glassman, R | 1 |
| Rood, L | 1 |
| Flowers, E | 1 |
| Thayer, S | 1 |
| Garza-Treviño, ES | 1 |
| Hollister, LE | 1 |
| Overall, JE | 1 |
| Alexander, WF | 1 |
| Thornton, L | 1 |
| Young, C | 1 |
| Bick, PA | 1 |
| Hannah, AL | 1 |
| Bartels, M | 1 |
| Heide, K | 1 |
| Mann, K | 1 |
| Schied, HW | 1 |
| Salam, SA | 1 |
| Kilzieh, N | 1 |
| Campbell, R | 1 |
| Ellison, JM | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| An Open-label, Randomized Trial of Intramuscular (IM) Olanzapine Versus Intramuscular Combination of Haloperidol and Lorazepam in the Treatment of Acute Agitation in Schizophrenia[NCT00797277] | Phase 3 | 67 participants (Actual) | Interventional | 2006-07-31 | Completed | ||
| Comparison of Oral Risperdal in Combination With Oral Lorazepam vs Standard Care Including Initial Conventional Neuroleptic IM Treatment, in Acute Schizophrenic Patients[NCT00249171] | Phase 4 | 226 participants (Actual) | Interventional | 2001-06-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Agitation was further assessed by the Agitation Calmness Evaluation Scale (ACES) (Copyright 1998, Eli Lilly and Company), a single-item scale developed by Eli Lilly and Company on which 1 indicates marked agitation; 2, moderate agitation; 3, mild agitation; 4, normal; 5, mild calmness; 6, moderate calmness; 7, marked calmness; 8, deep sleep; and 9, unable to be aroused. (NCT00797277)
Timeframe: from baseline to 120 minutes after first injection
| Intervention | units on a scale (Mean) |
|---|---|
| 1. IM Olanzapine | 2.14 |
| 2. IM Haloperidol Pus Lorazepam | 2.23 |
The primary efficacy measure was PANSS-EC, which was derived from the PANSS by its originators using a principal-components factor analysis, and includes the items of tension, uncooperativeness, hostility, poor impulse control and excitement.22 The score of each item ranges from 1 (normal) to 7 (most severe), with a total sum score ranging from 5 to 35. The changes in PANSS-EC from baseline to 2 hours after the first injection were compared. (NCT00797277)
Timeframe: from baseline to 120 minutes after first injection
| Intervention | units on a scale (Mean) |
|---|---|
| 1. IM Olanzapine | -10.2 |
| 2. IM Haloperidol Plus Lorazepam | -9.9 |
18 reviews available for lorazepam and Psychotic Disorders
| Article | Year |
|---|---|
Psychopharmacology of agitation in acute psychotic and manic episodes.
Topics: Antipsychotic Agents; Benzodiazepines; Drug Therapy, Combination; Haloperidol; Humans; Lorazepam; Ma | 2022 |
The pharmacological management of agitated and aggressive behaviour: A systematic review and meta-analysis.
Topics: Aggression; Anti-Anxiety Agents; Antipsychotic Agents; Benzodiazepines; Drug Therapy, Combination; H | 2019 |
Benzodiazepines for psychosis-induced aggression or agitation.
Topics: Acute Disease; Aggression; Anti-Dyskinesia Agents; Antipsychotic Agents; Benzodiazepines; Drug Thera | 2013 |
Catatonia in DSM 5: controversies regarding its psychopathology, clinical presentation and treatment response.
Topics: Antipsychotic Agents; Benzodiazepines; Catatonia; Clinical Trials as Topic; Concept Formation; Diagn | 2014 |
Haloperidol plus promethazine for psychosis-induced aggression.
Topics: Aggression; Benzodiazepines; Drug Therapy, Combination; Haloperidol; Humans; Lorazepam; Midazolam; P | 2016 |
Haloperidol plus promethazine for psychosis-induced aggression.
Topics: Aggression; Benzodiazepines; Drug Therapy, Combination; Haloperidol; Humans; Lorazepam; Midazolam; O | 2009 |
Othello syndrome. Preventing a tragedy when treating patients with delusional disorders.
Topics: Antipsychotic Agents; Combined Modality Therapy; Commitment of Mentally Ill; Cooperative Behavior; D | 2010 |
[Rapid tranquillisation; review of the literature and recommendations].
Topics: Aggression; Benzodiazepines; Conscious Sedation; Drug Therapy, Combination; Haloperidol; Humans; Hyp | 2011 |
Haloperidol for psychosis-induced aggression or agitation (rapid tranquillisation).
Topics: Aggression; Antipsychotic Agents; Aripiprazole; Clopenthixol; Dystonia; Haloperidol; Humans; Lorazep | 2012 |
Delirious mania: detection, diagnosis, and clinical management in the acute setting.
Topics: Bipolar Disorder; Catatonia; Delirium; Electroconvulsive Therapy; Humans; Hypnotics and Sedatives; L | 2013 |
Haloperidol plus promethazine for psychosis induced aggression.
Topics: Aggression; Drug Therapy, Combination; Haloperidol; Humans; Lorazepam; Midazolam; Promethazine; Psyc | 2005 |
Olanzapine IM or velotab for acutely disturbed/agitated people with suspected serious mental illnesses.
Topics: Aggression; Antipsychotic Agents; Benzodiazepines; Haloperidol; Humans; Injections, Intramuscular; L | 2005 |
Benzodiazepines alone or in combination with antipsychotic drugs for acute psychosis.
Topics: Acute Disease; Antipsychotic Agents; Benzodiazepines; Drug Therapy, Combination; Emergency Treatment | 2005 |
Emergency treatment of acute psychosis.
Topics: Acute Disease; Antipsychotic Agents; Benzodiazepines; Clozapine; Decision Trees; Drug Administration | 1998 |
Acute psychopharmacological management of the aggressive psychotic patient.
Topics: Acute Disease; Aggression; Antipsychotic Agents; Dose-Response Relationship, Drug; Haloperidol; Huma | 1999 |
Neuroleptic-induced catatonia as a stage in the progression toward neuroleptic malignant syndrome.
Topics: Adolescent; Catatonia; Drug Therapy, Combination; Haloperidol; Humans; Lorazepam; Male; Neuroleptic | 1992 |
Use of benzodiazepines to control disruptive behavior in inpatients.
Topics: Aggression; Benzodiazepines; Haloperidol; Hospitalization; Humans; Injections, Intramuscular; Loraze | 1988 |
Lorazepam treatment of psychogenic catatonia: an update.
Topics: Adult; Aged; Anemia, Pernicious; Catatonia; Female; Humans; Lorazepam; Male; Middle Aged; Pregnancy; | 1988 |
11 trials available for lorazepam and Psychotic Disorders
| Article | Year |
|---|---|
Abnormal GABAergic function and negative affect in schizophrenia.
Topics: Adult; Cerebral Cortex; Cross-Over Studies; Female; GABA Modulators; gamma-Aminobutyric Acid; Humans | 2014 |
Intramuscular olanzapine versus intramuscular haloperidol plus lorazepam for the treatment of acute schizophrenia with agitation: An open-label, randomized controlled trial.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Drug Therapy, Combination; Female; Haloperidol; Humans | 2015 |
Oral risperidone plus oral lorazepam versus standard care with intramuscular conventional neuroleptics in the initial phase of treating individuals with acute psychosis.
Topics: Acute Disease; Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Aggression; Antipsy | 2004 |
Randomized, controlled, double-blind multicenter comparison of the efficacy and tolerability of ziprasidone and olanzapine in acutely ill inpatients with schizophrenia or schizoaffective disorder.
Topics: Adolescent; Adult; Antipsychotic Agents; Benzodiazepines; Double-Blind Method; Drug Administration S | 2004 |
Oral risperidone with lorazepam versus oral zuclopenthixol with lorazepam in the treatment of acute psychosis in emergency psychiatry: a prospective, comparative, open-label study.
Topics: Adolescent; Adult; Aged; Aggression; Anti-Anxiety Agents; Antipsychotic Agents; Clopenthixol; Drug T | 2005 |
Long-acting injectable risperidone in the treatment of subjects with recent-onset psychosis: a preliminary study.
Topics: Adolescent; Adult; Antidepressive Agents; Blood Glucose; Body Mass Index; Cholesterol; Delayed-Actio | 2008 |
Haloperidol, lorazepam, or both for psychotic agitation? A multicenter, prospective, double-blind, emergency department study.
Topics: Adolescent; Adult; Anti-Anxiety Agents; Antipsychotic Agents; Brief Psychiatric Rating Scale; Demogr | 1997 |
Efficacy of lorazepam and haloperidol for rapid tranquilization in a psychiatric emergency room setting.
Topics: Administration, Oral; Adolescent; Adult; Anti-Anxiety Agents; Antipsychotic Agents; Double-Blind Met | 1997 |
Parenteral lorazepam versus parenteral haloperidol for the control of psychotic disruptive behavior.
Topics: Acute Disease; Adult; Aggression; Antipsychotic Agents; Double-Blind Method; Drug Therapy, Combinati | 1991 |
Efficacy of combinations of intramuscular antipsychotics and sedative-hypnotics for control of psychotic agitation.
Topics: Adolescent; Adult; Drug Combinations; Drug Therapy, Combination; Female; Haloperidol; Humans; Inject | 1989 |
Treatment of akathisia with lorazepam. An open clinical trial.
Topics: Adult; Akathisia, Drug-Induced; Antipsychotic Agents; Clinical Trials as Topic; Dyskinesia, Drug-Ind | 1987 |
53 other studies available for lorazepam and Psychotic Disorders
| Article | Year |
|---|---|
Catatonia in a 16-Year Old.
Topics: Adolescent; Catatonia; Humans; Lorazepam; Marijuana Abuse; Problem Behavior; Psychiatric Department, | 2021 |
Baclofen and catatonia: a case report.
Topics: Adult; Baclofen; Catatonia; Female; Humans; Lorazepam; Psychotic Disorders; Young Adult | 2022 |
Treatment of first-episode psychosis in patients with autism-spectrum disorder and intellectual deficiency
Topics: Adolescent; Akathisia, Drug-Induced; Antipsychotic Agents; Aripiprazole; Autism Spectrum Disorder; D | 2019 |
Cycloid psychosis and its longitudinal diagnosis: case report.
Topics: Adult; Antidepressive Agents; Antipsychotic Agents; Female; Haloperidol; Humans; Hypnotics and Sedat | 2020 |
Overcoming Complications in Management of a Difficult-to-Treat Adolescent with Schizoaffective Disorder.
Topics: Adolescent; Adolescent Psychiatry; Antidepressive Agents; Antipsychotic Agents; Diphenhydramine; Fem | 2020 |
Three Cases of COVID-19-related First Onset Brief Reactive Psychosis.
Topics: Adult; Antipsychotic Agents; Betacoronavirus; Coronavirus Infections; COVID-19; Delusions; Haloperid | 2020 |
Brief psychotic disorder associated with quarantine and mild COVID-19.
Topics: Adult; Anti-Anxiety Agents; Antipsychotic Agents; Anxiety Disorders; COVID-19; Humans; Lorazepam; Ma | 2020 |
Brief psychotic disorder with delusion content related to the COVID-19 outbreak.
Topics: Adult; Aggression; Anti-Anxiety Agents; Antipsychotic Agents; COVID-19; Delusions; Humans; Involunta | 2021 |
Stupor in a catatonic patient due to an interaction between high-dose lorazepam and valproic acid: a case report.
Topics: Adult; Anti-Anxiety Agents; Antimanic Agents; Catatonia; Drug Interactions; Female; Humans; Lorazepa | 2021 |
Psychiatric Complications of Primary Hyperparathyroidism and Mild Hypercalcemia.
Topics: Aged, 80 and over; Antipsychotic Agents; Depressive Disorder, Major; Female; GABA Modulators; Humans | 2017 |
Resurgence of catatonia following tapering or stoppage of lorazepam - A case series and implications.
Topics: Adult; Catatonia; Female; GABA Modulators; Humans; Lorazepam; Male; Psychotic Disorders; Recurrence; | 2017 |
The catatonic pupil: An unprivileged entity.
Topics: Adult; Antipsychotic Agents; Catatonia; Female; Humans; Lorazepam; Male; Psychotic Disorders; Pupil | 2018 |
Meditation induced psychosis: Case report.
Topics: Adult; Antipsychotic Agents; GABA Modulators; Haloperidol; Humans; Lorazepam; Male; Meditation; Prom | 2018 |
Catatonia due to alprazolam withdrawal.
Topics: Alprazolam; Antipsychotic Agents; Catatonia; Comorbidity; Humans; Lorazepam; Male; Middle Aged; Pati | 2018 |
Psychotic disorder after contact with a potentially rabid animal and post-exposure prophylactic anti-rabies treatment.
Topics: Adult; Anti-Anxiety Agents; Anticonvulsants; Antipsychotic Agents; Benzodiazepines; Clonazepam; Diag | 2014 |
Successful use of right unilateral ECT for catatonia: a case series.
Topics: Adolescent; Adult; Aged, 80 and over; Antipsychotic Agents; Bipolar Disorder; Catatonia; Depressive | 2014 |
[QTc prolongation induced by intravenous sedation with Haloperidol, Prothipendyl and Lorazepam].
Topics: Adult; Age Factors; Aged; Comorbidity; Conscious Sedation; Drug Synergism; Drug Therapy, Combination | 2014 |
An atypical case of neuroleptic malignant syndrome precipitated by valproate.
Topics: Anticonvulsants; Antipsychotic Agents; Benzodiazepines; Benzothiazoles; Dopamine Agonists; Drug Ther | 2014 |
A Woman With Catatonia, What To Do After ECT Fails: A Case Report.
Topics: Antimanic Agents; Catatonia; Electroconvulsive Therapy; Electroencephalography; Female; GABA Modulat | 2016 |
Sudden-Onset Catatonia Following Clozapine Withdrawal: A Case Report.
Topics: Antipsychotic Agents; C-Reactive Protein; Catatonia; Clozapine; Creatine Kinase; Dantrolene; Drug Mo | 2016 |
Polysubstance-induced relapse of schizoaffective disorder refractory to high-dose antipsychotic medications: a case report.
Topics: Adult; Amphetamine-Related Disorders; Antipsychotic Agents; Chlorpromazine; Clopenthixol; Droperidol | 2016 |
Reversal of preoperative catatonic state by surgical resection of an adult-onset craniopharyngioma: case report and review of the literature.
Topics: Brain; Catatonia; Craniopharyngioma; Hormones; Humans; Hypnotics and Sedatives; Lorazepam; Male; Mid | 2009 |
[Catatonic dilemma in a schizoaffective patient with combined lithium-risperidone administration].
Topics: Antimanic Agents; Antipsychotic Agents; Brain; Catatonia; Clozapine; Diagnosis, Differential; Dopami | 2010 |
[Catatonia].
Topics: Adult; Catatonia; Female; Humans; Lorazepam; Male; Mental Disorders; Mood Disorders; Psychotic Disor | 2010 |
[First-episode mania with psychotic features induced by over-the-counter diet aids containing sibutramine].
Topics: Appetite Depressants; Bipolar Disorder; Cyclobutanes; Humans; Hypnotics and Sedatives; Lorazepam; No | 2010 |
Electroconvulsive therapy in the treatment of delirious mania: a report of 2 patients.
Topics: Adolescent; Antimanic Agents; Bipolar Disorder; Catatonia; Delirium; Electroconvulsive Therapy; Fema | 2010 |
Cases of catatonia on an academic electroconvulsive therapy service: lessons to learn.
Topics: Aged; Aged, 80 and over; Anxiety Disorders; Catatonia; Depressive Disorder; Depressive Disorder, Maj | 2011 |
An unusual presentation of catatonia in a patient with schizoaffective disorder.
Topics: Behavior; Catatonia; Depressive Disorder; Female; Fibrin Fibrinogen Degradation Products; Humans; Hy | 2011 |
Neuroleptic-induced catatonia in two hospitalized patients.
Topics: Adult; Antipsychotic Agents; Dopamine D2 Receptor Antagonists; Female; Haloperidol; Hospitalization; | 2012 |
Catatonia and encephalopathy associated with paliperidone palmitate.
Topics: Aged; Antipsychotic Agents; Catatonia; Female; Humans; Isoxazoles; Lorazepam; Male; Neuroleptic Mali | 2012 |
Psychosis from a bath salt product containing flephedrone and MDPV with serum, urine, and product quantification.
Topics: Alkaloids; Benzodioxoles; Designer Drugs; Droperidol; Humans; Insufflation; Lorazepam; Male; Propiop | 2012 |
Stupor due to possible interaction between Lorazepam and valproic acid: report of two cases.
Topics: Anti-Anxiety Agents; Anticonvulsants; Diagnosis, Differential; Drug Interactions; Drug Therapy, Comb | 2012 |
Catatonic features noted in patients with post-partum mental illness.
Topics: Adult; Benzodiazepines; Catatonia; Cross-Sectional Studies; Depression, Postpartum; Depressive Disor | 2004 |
Lorazepam-induced prolongation of the QT interval in a patient with schizoaffective disorder and complete AV block.
Topics: Adult; Anti-Anxiety Agents; Female; Heart Block; Humans; Long QT Syndrome; Lorazepam; Psychotic Diso | 2004 |
Persistent psychotic disorder in an adolescent with a past history of butane gas dependence.
Topics: Adolescent; Antipsychotic Agents; Butanes; Diagnostic and Statistical Manual of Mental Disorders; Ha | 2004 |
Re: Lorazepam-induced prolongation of the QT interval in a patient with schizoaffective disorder and complete AV block.
Topics: Adult; Anti-Anxiety Agents; Drug Interactions; Drug Therapy, Combination; Electrocardiography; Femal | 2005 |
Catatonia and psychosis in a patient with AIDS: treatment with lorazepam and aripiprazole.
Topics: Acquired Immunodeficiency Syndrome; Adult; Anti-Anxiety Agents; Anti-HIV Agents; Antipsychotic Agent | 2005 |
Neuroleptic malignant syndrome precipitated by haloperidol following clozapine discontinuation.
Topics: Adult; Anti-Anxiety Agents; Antiparkinson Agents; Antipsychotic Agents; Bromocriptine; Clozapine; Cr | 2005 |
A16-year-old girl with excited catatonia treated with low-dose oral Lorazepam.
Topics: Adolescent; Bipolar Disorder; Catatonia; Delirium; Dose-Response Relationship, Drug; Female; Humans; | 2005 |
Manifestation of multiple sclerosis with paranoid-hallucinatory psychosis.
Topics: Adult; Antipsychotic Agents; Aripiprazole; Diet; Epilepsy, Generalized; Female; Hallucinations; Huma | 2006 |
Revisiting cycloid psychosis: a case of an acute, transient and recurring psychotic disorder.
Topics: Acute Disease; Aged; Benzodiazepines; Cognition Disorders; Delusions; Diagnosis, Differential; Diagn | 2006 |
[Somnolence of unknown origin--illness or drug problem?].
Topics: Anticonvulsants; Carbamazepine; Diagnosis, Differential; Disorders of Excessive Somnolence; Drug Int | 2006 |
[Lorazepam. Evaluation after extensive use].
Topics: Animals; Anti-Anxiety Agents; Anxiety Disorders; Bipolar Disorder; Depressive Disorder; Dogs; Humans | 1981 |
[Ataractic treatment in psychiatry and general medicine. Review of preparations. 9].
Topics: Adjustment Disorders; Anthracenes; Anti-Anxiety Agents; Benzodiazepines; Humans; Lorazepam; Maprotil | 1983 |
Treatment of catatonic stupor with oral lorazepam in 14-year-old psychotic boy.
Topics: Adolescent; Catatonia; Haloperidol; Humans; Lorazepam; Male; Psychotic Disorders | 1993 |
Management of acute psychosis.
Topics: Acute Disease; Benzodiazepines; Health Services Accessibility; Humans; Injections, Intramuscular; Lo | 2000 |
Brief acute psychosis following hysterectomy in ethnopsychiatric context.
Topics: Acute Disease; Adult; Anti-Anxiety Agents; Antipsychotic Agents; Anxiety Disorders; China; Culture; | 2000 |
Risperidone liquid concentrate and oral lorazepam versus intramuscular haloperidol and intramuscular lorazepam for treatment of psychotic agitation.
Topics: Acute Disease; Administration, Oral; Adult; Antipsychotic Agents; Drug Therapy, Combination; Emergen | 2001 |
Loxapine-lorazepam-induced hypotension and stupor.
Topics: Adult; Cognition Disorders; Consciousness Disorders; Dibenzoxazepines; Drug Therapy, Combination; Fe | 1989 |
Intramuscular lorazepam to restrain violent patients.
Topics: Female; Humans; Injections, Intramuscular; Lorazepam; Male; Pilot Projects; Psychotic Disorders; Ret | 1986 |
New pharmacologic approaches in the treatment of psychosis. Proceedings of a symposium. Philadelphia, June 29, 1985.
Topics: Haloperidol; Humans; Lorazepam; Psychotic Disorders | 1986 |
Alternative approaches in the treatment of psychotic agitation.
Topics: Combined Modality Therapy; Haloperidol; Humans; Injections, Intramuscular; Lorazepam; Psychomotor Ag | 1986 |
Emergency treatment of acute psychosis, agitation, and anxiety.
Topics: Anxiety Disorders; Diazepam; Droperidol; Emergencies; Haloperidol; Humans; Lorazepam; Panic; Propran | 1985 |