lorazepam has been researched along with Psychomotor Agitation in 93 studies
Lorazepam: A benzodiazepine used as an anti-anxiety agent with few side effects. It also has hypnotic, anticonvulsant, and considerable sedative properties and has been proposed as a preanesthetic agent.
Psychomotor Agitation: A feeling of restlessness associated with increased motor activity. This may occur as a manifestation of nervous system drug toxicity or other conditions.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Acutely agitated patients with schizophrenia or schizoaffective disorder (n = 67) were randomized to receive 10 mg IM olanzapine (n = 37) or 5 mg IM haloperidol plus 2 mg IM lorazepam (n = 30)." | 9.20 | Intramuscular olanzapine versus intramuscular haloperidol plus lorazepam for the treatment of acute schizophrenia with agitation: An open-label, randomized controlled trial. ( Chen, HH; Chen, YH; Hsieh, MH; Huang, CL; Huang, GH; Hwang, TJ; Hwu, HG, 2015) |
| "We conducted a prospective double-blind study of accelerated dose titration of olanzapine in the treatment of newly admitted acutely agitated patients with schizophrenia." | 9.11 | Efficacy of accelerated dose titration of olanzapine with adjunctive lorazepam to treat acute agitation in schizophrenia. ( Ahl, J; Kinon, BJ; McMullen, E; Rotelli, MD, 2004) |
| "This double-blind study investigated the efficacy and safety of rapid-acting intramuscular olanzapine in treating agitation associated with Alzheimer's disease and/or vascular dementia." | 9.10 | Comparison of rapidly acting intramuscular olanzapine, lorazepam, and placebo: a double-blind, randomized study in acutely agitated patients with dementia. ( Beasley, CM; Beckett, LM; Breier, A; David, SR; Feldman, PD; Jones, B; Meehan, KM; Mintzer, JE; Nisivoccia, JR; Wang, H, 2002) |
| "To examine whether haloperidol plus promethazine is an effective treatment for psychosis-induced aggression." | 8.93 | Haloperidol plus promethazine for psychosis-induced aggression. ( Alexander, J; Allen, MH; Gandhi, P; Huf, G, 2016) |
| "Haloperidol, used alone is recommended to help calm situations of aggression with people with psychosis." | 8.88 | Haloperidol for psychosis-induced aggression or agitation (rapid tranquillisation). ( Adams, CE; Jones, H; Powney, MJ, 2012) |
| "To examine whether haloperidol plus promethazine is an effective treatment for psychosis induced agitation/aggression." | 8.85 | Haloperidol plus promethazine for psychosis-induced aggression. ( Alexander, J; Allen, MH; Huf, G; Raveendran, NS, 2009) |
| "To examine whether haloperidol plus promethazine is an effective treatment for psychosis induced agitation/aggression." | 8.82 | Haloperidol plus promethazine for psychosis induced aggression. ( Alexander, J; Allen, MH; Huf, G, 2005) |
| "Practice guidelines recommend the use of low dose haloperidol when medication is needed to treat delirium with acute agitation in hospitalized older people." | 7.79 | Haloperidol overdosing in the treatment of agitated hospitalized older people with delirium: a retrospective chart review from a community teaching hospital. ( Dorokhine, I; Knapp, CM; Musuku, M; Patel, N; Zirker, W, 2013) |
| "Lorazepam was also given as needed (total dose, < or =4 mg/d) but not in place of a study drug dose increase." | 6.73 | Olanzapine versus aripiprazole for the treatment of agitation in acutely ill patients with schizophrenia. ( Chen, L; Kinon, BJ; Kollack-Walker, S; Sniadecki, J; Stauffer, VL, 2008) |
| "This was a pre-planned secondary analysis of a double-blind, randomized clinical trial comparing the use of a single dose of lorazepam plus haloperidol versus placebo plus haloperidol in patients with agitated delirium." | 5.41 | Association among rescue neuroleptic use, agitation, and perceived comfort: secondary analysis of a randomized clinical trial on agitated delirium. ( Bruera, E; Chen, M; Hui, D; Tang, M, 2021) |
| "The current study was a secondary analysis of a randomized controlled trial to compare the effect of lorazepam versus placebo as an adjuvant to haloperidol for persistent agitation in patients with delirium." | 5.27 | The minimal clinically important difference of the Richmond Agitation-Sedation Scale in patients with cancer with agitated delirium. ( Arthur, J; Bruera, E; Dalal, S; Dev, R; Dibaj, SS; Hess, K; Hui, D; Reddy, S, 2018) |
| " Acutely agitated patients with schizophrenia or schizoaffective disorder (n = 67) were randomized to receive 10 mg IM olanzapine (n = 37) or 5 mg IM haloperidol plus 2 mg IM lorazepam (n = 30)." | 5.20 | Intramuscular olanzapine versus intramuscular haloperidol plus lorazepam for the treatment of acute schizophrenia with agitation: An open-label, randomized controlled trial. ( Chen, HH; Chen, YH; Hsieh, MH; Huang, CL; Huang, GH; Hwang, TJ; Hwu, HG, 2015) |
| "We conducted a prospective double-blind study of accelerated dose titration of olanzapine in the treatment of newly admitted acutely agitated patients with schizophrenia." | 5.11 | Efficacy of accelerated dose titration of olanzapine with adjunctive lorazepam to treat acute agitation in schizophrenia. ( Ahl, J; Kinon, BJ; McMullen, E; Rotelli, MD, 2004) |
| " In 3 double-blind studies, acutely agitated patients with schizophrenia (N = 311), bipolar mania (N = 201), or dementia (N = 206) were treated with intramuscular (1-3 injections/24 hrs) olanzapine (2." | 5.10 | Calming versus sedative effects of intramuscular olanzapine in agitated patients. ( Alaka, K; Battaglia, J; Lindborg, SR; Meehan, K; Wright, P, 2003) |
| "This double-blind study investigated the efficacy and safety of rapid-acting intramuscular olanzapine in treating agitation associated with Alzheimer's disease and/or vascular dementia." | 5.10 | Comparison of rapidly acting intramuscular olanzapine, lorazepam, and placebo: a double-blind, randomized study in acutely agitated patients with dementia. ( Beasley, CM; Beckett, LM; Breier, A; David, SR; Feldman, PD; Jones, B; Meehan, KM; Mintzer, JE; Nisivoccia, JR; Wang, H, 2002) |
| "We now present data from a randomized, double-blind clinical study of lorazepam versus haloperidol in 20 hospitalized patients with a DSM-III-R diagnosis of bipolar disorder who were being treated concomitantly with lithium." | 5.07 | Adjunctive treatment of manic agitation with lorazepam versus haloperidol: a double-blind study. ( Creelman, WL; Lenox, RH; Newhouse, PA; Whitaker, TM, 1992) |
| "To examine whether haloperidol plus promethazine is an effective treatment for psychosis-induced aggression." | 4.93 | Haloperidol plus promethazine for psychosis-induced aggression. ( Alexander, J; Allen, MH; Gandhi, P; Huf, G, 2016) |
| "Haloperidol, used alone is recommended to help calm situations of aggression with people with psychosis." | 4.88 | Haloperidol for psychosis-induced aggression or agitation (rapid tranquillisation). ( Adams, CE; Jones, H; Powney, MJ, 2012) |
| "To examine whether haloperidol plus promethazine is an effective treatment for psychosis induced agitation/aggression." | 4.85 | Haloperidol plus promethazine for psychosis-induced aggression. ( Alexander, J; Allen, MH; Huf, G; Raveendran, NS, 2009) |
| "To examine whether haloperidol plus promethazine is an effective treatment for psychosis induced agitation/aggression." | 4.82 | Haloperidol plus promethazine for psychosis induced aggression. ( Alexander, J; Allen, MH; Huf, G, 2005) |
| "Over 67 days, 1,461 patients were screened in the ED, 269 had bipolar I or schizophrenia, 194 of whom had a contraindication to inhaled loxapine leaving 75 eligible patients; preconsent was obtained in 43 patients." | 3.91 | Study Enrollment When "Preconsent" Is Utilized for a Randomized Clinical Trial of Two Treatments for Acute Agitation in the Emergency Department. ( Cole, JB; Driver, BE; Klein, LR; Mullinax, SZ; Nordstrom, KD; Wilson, MP, 2019) |
| "The World Health Organization recommends that anxiety, depression, agitation and delirium at end of life should be treated with drugs such as lorazepam, diazepam, midazolam and haloperidol." | 3.83 | Look again at psychedelic drugs. ( Cameron, R, 2016) |
| "Practice guidelines recommend the use of low dose haloperidol when medication is needed to treat delirium with acute agitation in hospitalized older people." | 3.79 | Haloperidol overdosing in the treatment of agitated hospitalized older people with delirium: a retrospective chart review from a community teaching hospital. ( Dorokhine, I; Knapp, CM; Musuku, M; Patel, N; Zirker, W, 2013) |
| " Indications for droperidol included agitation, 68 (86%); nausea/vomiting, 7 (9%); headache, 2 (3%); and other pain, 2 (3%)." | 3.76 | Droperidol use in pediatric emergency department patients. ( Sacchetti, A; Szwak, K, 2010) |
| "Analysis 1 found that nonsedated patients with bipolar I disorder and schizophrenia showed significant decreases in PEC scores following treatment with aripiprazole IM (p < 0." | 3.74 | Intramuscular aripiprazole in the control of agitation. ( Citrome, LL; Crandall, DT; Currier, GW; Manos, G; McQuade, R; Oren, D; Pikalov, AA; Zimbroff, DL, 2007) |
| "Droperidol was more effective than lorazepam or either dose of ziprasidone for the treatment of acute agitation in the ED and caused fewer episodes of respiratory depression." | 3.01 | Randomized Double-blind Trial of Intramuscular Droperidol, Ziprasidone, and Lorazepam for Acute Undifferentiated Agitation in the Emergency Department. ( Biros, MH; Cole, JB; Driver, BE; Martel, ML; Miner, JR, 2021) |
| "Lorazepam was also given as needed (total dose, < or =4 mg/d) but not in place of a study drug dose increase." | 2.73 | Olanzapine versus aripiprazole for the treatment of agitation in acutely ill patients with schizophrenia. ( Chen, L; Kinon, BJ; Kollack-Walker, S; Sniadecki, J; Stauffer, VL, 2008) |
| "Lorazepam alone was as effective as lorazepam plus haloperidol or lorazepam plus risperidone in this small trial." | 2.72 | Risperidone versus haloperidol, in combination with lorazepam, in the treatment of acute agitation and psychosis: a pilot, randomized, double-blind, placebo-controlled trial. ( Currier, GW; McMullan, JT; Veser, BD; Veser, FH; Zealberg, J, 2006) |
| "Midazolam has a significantly shorter time to onset of sedation and a more rapid time to arousal than lorazepam or haloperidol." | 2.71 | A prospective, double-blind, randomized trial of midazolam versus haloperidol versus lorazepam in the chemical restraint of violent and severely agitated patients. ( Dresden, GM; Levitt, MA; Nobay, F; Simon, BC, 2004) |
| " Mean score improvements at 30, 60, and 120 minutes after dosing were significant at each timepoint in both groups (p <." | 2.71 | Acute treatment of psychotic agitation: a randomized comparison of oral treatment with risperidone and lorazepam versus intramuscular treatment with haloperidol and lorazepam. ( Bossie, CA; Chou, JC; Currier, GW; Feifel, D; Gharabawi, GM; Mahmoud, RA; Turkoz, I, 2004) |
| " These findings suggest that intramuscular olanzapine is a safe and effective treatment for reducing acute agitation in patients with bipolar mania." | 2.70 | A double-blind, randomized comparison of the efficacy and safety of intramuscular injections of olanzapine, lorazepam, or placebo in treating acutely agitated patients diagnosed with bipolar mania. ( Breier, A; David, S; Janicak, P; Koch, M; Meehan, K; Rizk, R; Small, J; Tohen, M; Tran, P; Walker, D; Zhang, F, 2001) |
| "The drop in the akathisia score from a pretreatment value of 1." | 2.66 | Treatment of akathisia with lorazepam. An open clinical trial. ( Bartels, M; Heide, K; Mann, K; Schied, HW, 1987) |
| "When haloperidol and midazolam were compared with olanzapine, there was some evidence the combination was superior in terms of improvement, sedation and behaviour." | 2.49 | Benzodiazepines for psychosis-induced aggression or agitation. ( Beck, A; Gillies, D; Rathbone, J; Sampson, S, 2013) |
| "lorazepam; 6 weeks), and in restlessness and agitation (vs." | 2.46 | Efficacy and safety of silexan, a new, orally administered lavender oil preparation, in subthreshold anxiety disorder - evidence from clinical trials. ( Dienel, A; Gastpar, M; Kasper, S; Möller, HJ; Müller, WE; Schläfke, S; Volz, HP, 2010) |
| "Bilateral intraocular pressures were monitored before and after the first 7 ECTs and intermittently after ECT for 10 months of maintenance ECT." | 1.40 | Stability of intraocular pressure after retinal reattachment surgery during electroconvulsive therapy for intractable self-injury in a 12-year-old autistic boy. ( Reti, IM; Wachtel, LE; Ying, H, 2014) |
| "Catatonia is a syndrome of motor dysregulation, usually associated with psychiatric, neurological, systemic and drug-related diseases." | 1.39 | Agitation after minor trauma: combativeness as a cardinal catatonic feature. ( Luykx, JJ; Post, EH; van der Erf, M; Van Hecke, J, 2013) |
| "All four of the reviewed cases with myokymia of the shoulders were intubated and none without it were intubated." | 1.35 | Fasciculations after rattlesnake envenomations: a retrospective statewide poison control system study. ( Cantrell, FL; Vohra, R; Williams, SR, 2008) |
| "ziprasidone for the treatment of acute agitation." | 1.33 | Naturalistic study of intramuscular ziprasidone versus conventional agents in agitated elderly patients: retrospective findings from a psychiatric emergency service. ( Francis, A; Kohen, I; Preval, H; Southard, R, 2005) |
| "Haloperidol was administered more often to elderly patients (p=0." | 1.31 | Frequency, severity, and treatment of agitation in young versus elderly patients in the ICU. ( Berthiaume, D; Fraser, GL; Prato, BS; Riker, RR; Wilkins, ML, 2000) |
| "Oral treatment with risperidone and lorazepam appears to be a tolerable and comparable alternative to intramuscular haloperidol and lorazepam for short-term treatment of agitated psychosis in patients who accept oral medications." | 1.31 | Risperidone liquid concentrate and oral lorazepam versus intramuscular haloperidol and intramuscular lorazepam for treatment of psychotic agitation. ( Currier, GW; Simpson, GM, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (13.98) | 18.7374 |
| 1990's | 11 (11.83) | 18.2507 |
| 2000's | 34 (36.56) | 29.6817 |
| 2010's | 25 (26.88) | 24.3611 |
| 2020's | 10 (10.75) | 2.80 |
| Authors | Studies |
|---|---|
| Conrardy, MJ | 1 |
| Tyler, DJ | 1 |
| Cruz, DS | 1 |
| Fant, AL | 1 |
| Malik, S | 1 |
| Lank, PM | 1 |
| Kim, HS | 1 |
| Thiemann, P | 1 |
| Roy, D | 1 |
| Huecker, M | 1 |
| Senn, J | 1 |
| Javed, J | 1 |
| Thomas, A | 1 |
| Shreffler, J | 1 |
| Shaw, I | 1 |
| Jeffers, T | 1 |
| Darling, B | 1 |
| Edwards, C | 1 |
| Vadiei, N | 1 |
| Stetson, SR | 1 |
| Osser, DN | 1 |
| Allen, PJ | 1 |
| Johanson, KE | 1 |
| Reveles, KR | 1 |
| Neff, LA | 1 |
| Lock, AE | 1 |
| Lin, J | 1 |
| Figuerado, Y | 1 |
| Montgomery, A | 1 |
| Lee, J | 1 |
| Cannis, M | 1 |
| Norton, VC | 1 |
| Calvo, R | 1 |
| Sikand, H | 1 |
| Martel, ML | 1 |
| Driver, BE | 2 |
| Miner, JR | 1 |
| Biros, MH | 1 |
| Cole, JB | 2 |
| Marouda, K | 1 |
| Mantonakis, L | 1 |
| Kollias, K | 1 |
| Tang, M | 1 |
| Chen, M | 1 |
| Bruera, E | 2 |
| Hui, D | 2 |
| Hess, K | 1 |
| Dibaj, SS | 1 |
| Arthur, J | 1 |
| Dev, R | 1 |
| Dalal, S | 1 |
| Reddy, S | 1 |
| Reddy, MSS | 1 |
| Achary, U | 1 |
| Harbishettar, V | 1 |
| Sivakumar, PT | 1 |
| Varghese, M | 1 |
| Klein, LR | 1 |
| Mullinax, SZ | 1 |
| Nordstrom, KD | 1 |
| Wilson, MP | 1 |
| Bak, M | 1 |
| Weltens, I | 1 |
| Bervoets, C | 1 |
| De Fruyt, J | 1 |
| Samochowiec, J | 1 |
| Fiorillo, A | 1 |
| Sampogna, G | 1 |
| Bienkowski, P | 1 |
| Preuss, WU | 1 |
| Misiak, B | 1 |
| Frydecka, D | 1 |
| Samochowiec, A | 1 |
| Bak, E | 1 |
| Drukker, M | 1 |
| Dom, G | 1 |
| Bregstein, JS | 1 |
| Wagh, AM | 1 |
| Tsze, DS | 1 |
| Mann, E | 1 |
| Haastert, B | 1 |
| Böhmdorfer, B | 1 |
| Frühwald, T | 1 |
| Iglseder, B | 1 |
| Roller-Wirnsberger, R | 1 |
| Meyer, G | 1 |
| Gillies, D | 1 |
| Sampson, S | 1 |
| Beck, A | 1 |
| Rathbone, J | 1 |
| Zirker, W | 1 |
| Dorokhine, I | 1 |
| Knapp, CM | 1 |
| Patel, N | 1 |
| Musuku, M | 1 |
| Luykx, JJ | 1 |
| Post, EH | 1 |
| van der Erf, M | 1 |
| Van Hecke, J | 1 |
| Wachtel, LE | 1 |
| Reti, IM | 1 |
| Ying, H | 1 |
| Nishiyama, A | 1 |
| Matsumoto, H | 1 |
| Froberg, BA | 1 |
| Levine, M | 1 |
| Beuhler, MC | 1 |
| Judge, BS | 1 |
| Moore, PW | 1 |
| Engebretsen, KM | 1 |
| Mckeown, NJ | 1 |
| Rosenbaum, CD | 1 |
| Young, AC | 1 |
| Rusyniak, DE | 1 |
| Huang, CL | 1 |
| Hwang, TJ | 1 |
| Chen, YH | 1 |
| Huang, GH | 1 |
| Hsieh, MH | 1 |
| Chen, HH | 1 |
| Hwu, HG | 1 |
| Hayes, A | 1 |
| Russ, MJ | 1 |
| OʼRear, JM | 1 |
| Prahlow, JA | 1 |
| Cameron, R | 1 |
| Gagnon, DJ | 1 |
| Fontaine, GV | 1 |
| Smith, KE | 1 |
| Riker, RR | 2 |
| Miller, RR | 1 |
| Lerwick, PA | 1 |
| Lucas, FL | 1 |
| Dziodzio, JT | 1 |
| Sihler, KC | 1 |
| Fraser, GL | 2 |
| Huf, G | 4 |
| Alexander, J | 4 |
| Gandhi, P | 1 |
| Allen, MH | 3 |
| Kousgaard, SJ | 1 |
| Licht, RW | 1 |
| Nielsen, RE | 1 |
| Kinon, BJ | 2 |
| Stauffer, VL | 1 |
| Kollack-Walker, S | 1 |
| Chen, L | 1 |
| Sniadecki, J | 1 |
| Jaffe, A | 1 |
| Levine, J | 1 |
| Citrome, L | 2 |
| Raveendran, NS | 1 |
| Hardy, D | 1 |
| Coutinho, ES | 1 |
| Adams, CE | 2 |
| Birmingham, C | 1 |
| Ban, K | 1 |
| Rosen, P | 1 |
| Wolfe, R | 1 |
| Davis, D | 1 |
| Sakles, J | 1 |
| Bramwell, K | 1 |
| Sanchez, LD | 1 |
| Szwak, K | 1 |
| Sacchetti, A | 1 |
| Kasper, S | 1 |
| Gastpar, M | 1 |
| Müller, WE | 1 |
| Volz, HP | 1 |
| Möller, HJ | 1 |
| Dienel, A | 1 |
| Schläfke, S | 1 |
| Emmerson, B | 1 |
| Moudgil, V | 1 |
| Woodbridge, A | 1 |
| Burrows, D | 1 |
| Kingswell, B | 1 |
| Kubler, P | 1 |
| McMahon, K | 1 |
| LeBlanc, JM | 1 |
| Dasta, JF | 1 |
| Pruchnicki, MC | 1 |
| Gerlach, A | 1 |
| Cook, C | 1 |
| Watt, KM | 1 |
| Walgos, J | 1 |
| Cheifetz, IM | 1 |
| Turner, DA | 1 |
| Powney, MJ | 1 |
| Jones, H | 1 |
| Maccioli, GA | 1 |
| Tuohy, KA | 1 |
| Nicholson, WJ | 1 |
| Schiffman, F | 1 |
| Multz, AS | 1 |
| Battaglia, J | 2 |
| Lindborg, SR | 1 |
| Alaka, K | 1 |
| Meehan, K | 2 |
| Wright, P | 1 |
| Currier, GW | 4 |
| Chou, JC | 1 |
| Feifel, D | 1 |
| Bossie, CA | 1 |
| Turkoz, I | 1 |
| Mahmoud, RA | 1 |
| Gharabawi, GM | 1 |
| Ahl, J | 1 |
| Rotelli, MD | 1 |
| McMullen, E | 1 |
| Nobay, F | 2 |
| Simon, BC | 1 |
| Levitt, MA | 1 |
| Dresden, GM | 1 |
| Tharyan, P | 1 |
| Adams, C | 1 |
| John, T | 1 |
| Mol, C | 1 |
| Philip, J | 1 |
| Lewin, MR | 1 |
| Montauk, L | 1 |
| Shalit, M | 1 |
| Srihari, VH | 1 |
| Lee, TS | 1 |
| Rohrbaugh, RM | 1 |
| D'Souza, DC | 1 |
| Kohen, I | 1 |
| Preval, H | 1 |
| Southard, R | 1 |
| Francis, A | 1 |
| Veser, FH | 1 |
| Veser, BD | 1 |
| McMullan, JT | 1 |
| Zealberg, J | 1 |
| Reid, C | 1 |
| Zimbroff, DL | 2 |
| Marcus, RN | 1 |
| Manos, G | 2 |
| Stock, E | 1 |
| McQuade, RD | 1 |
| Auby, P | 1 |
| Oren, DA | 1 |
| Citrome, LL | 1 |
| Oren, D | 1 |
| McQuade, R | 1 |
| Pikalov, AA | 1 |
| Crandall, DT | 1 |
| Weitz, G | 1 |
| Homann, N | 1 |
| von Jagow, DC | 1 |
| Wellhöner, P | 1 |
| Sauer, A | 1 |
| Ludwig, D | 1 |
| Rasmussen, KG | 1 |
| Mueller, M | 1 |
| Knapp, RG | 1 |
| Husain, MM | 1 |
| Rummans, TA | 1 |
| Sampson, SM | 1 |
| O'Connor, MK | 1 |
| Petrides, G | 1 |
| Fink, M | 1 |
| Kellner, CH | 1 |
| Preskorn, SH | 1 |
| Vohra, R | 1 |
| Cantrell, FL | 1 |
| Williams, SR | 1 |
| Fowler, SB | 1 |
| Hertzog, J | 1 |
| Wagner, BK | 1 |
| Pohlman, AS | 1 |
| Simpson, KP | 1 |
| Hall, JB | 1 |
| Tesar, GE | 1 |
| Maltsberger, JT | 1 |
| Prato, BS | 1 |
| Berthiaume, D | 1 |
| Wilkins, ML | 1 |
| Stanislav, SW | 1 |
| Childs, A | 1 |
| Duggal, HS | 1 |
| Simpson, GM | 2 |
| Zhang, F | 1 |
| David, S | 1 |
| Tohen, M | 1 |
| Janicak, P | 1 |
| Small, J | 1 |
| Koch, M | 1 |
| Rizk, R | 1 |
| Walker, D | 1 |
| Tran, P | 1 |
| Breier, A | 2 |
| Hatch, CD | 1 |
| Lund, BC | 1 |
| Perry, PJ | 1 |
| Meehan, KM | 1 |
| Wang, H | 1 |
| David, SR | 1 |
| Nisivoccia, JR | 1 |
| Jones, B | 1 |
| Beasley, CM | 1 |
| Feldman, PD | 1 |
| Mintzer, JE | 1 |
| Beckett, LM | 1 |
| Lenox, RH | 2 |
| Newhouse, PA | 1 |
| Creelman, WL | 1 |
| Whitaker, TM | 1 |
| Little, JD | 1 |
| Taghavi, EH | 1 |
| Ancill, RJ | 1 |
| Carlyle, WW | 1 |
| Liang, RA | 1 |
| Holliday, SG | 1 |
| Bross, MH | 1 |
| Alexander, W | 1 |
| Yassa, R | 2 |
| Bloom, D | 1 |
| Salzman, C | 3 |
| Miyawaki, EK | 1 |
| Soloman, D | 1 |
| Lopez, A | 1 |
| Rebollo, J | 1 |
| Groulx, B | 1 |
| Garza-Treviño, ES | 1 |
| Hollister, LE | 1 |
| Overall, JE | 1 |
| Alexander, WF | 1 |
| Adler, L | 1 |
| Angrist, B | 1 |
| Peselow, E | 1 |
| Corwin, J | 1 |
| Rotrosen, J | 1 |
| Bartels, M | 1 |
| Heide, K | 1 |
| Mann, K | 1 |
| Schied, HW | 1 |
| Cerri, C | 1 |
| Cocco, E | 1 |
| Rovati, L | 1 |
| Majeau-Chargois, D | 1 |
| Ward, ME | 1 |
| Saklad, SR | 1 |
| Ereshefsky, L | 1 |
| Modell, JG | 2 |
| Green, AI | 1 |
| Rodriguez-Villa, F | 1 |
| Jaskiw, GI | 1 |
| Campbell, R | 1 |
| Weiner, S | 1 |
| Ellison, JM | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Open-label Randomized Controlled Trial of Oral Transmucosal Haloperidol and Olanzapine in the Treatment of Terminal Delirium[NCT04750395] | Phase 2 | 80 participants (Anticipated) | Interventional | 2021-09-01 | Recruiting | ||
| An Observational Study of Anti-Psychotic Medication for the Treatment of Agitation in the Emergency Department[NCT02877108] | 100 participants (Anticipated) | Observational | 2016-04-30 | Recruiting | |||
| An Open-label, Randomized Trial of Intramuscular (IM) Olanzapine Versus Intramuscular Combination of Haloperidol and Lorazepam in the Treatment of Acute Agitation in Schizophrenia[NCT00797277] | Phase 3 | 67 participants (Actual) | Interventional | 2006-07-31 | Completed | ||
| A Randomized, Double-blind, Placebo-controlled, Parallel-group Study of Dexmedetomidine (Precedex®), With Lorazepam Rescue, for the Management of Severe Alcohol Withdrawal Syndrome (AWS) and Alcohol Withdrawal Delirium (AWD)[NCT01362205] | Phase 4 | 49 participants (Actual) | Interventional | 2012-03-31 | Terminated (stopped due to DSMB recommendation for slow enrollment) | ||
| Rapid Tranquilization of Violent or Agitated People in Psychiatric Emergency Settings- A Pragmatic Randomized Controlled Trial of Intramuscular Olanzepine Vs. Intramuscular Haloperidol + Promethazine.[NCT00455234] | Phase 3 | 300 participants | Interventional | 2005-09-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Agitation was further assessed by the Agitation Calmness Evaluation Scale (ACES) (Copyright 1998, Eli Lilly and Company), a single-item scale developed by Eli Lilly and Company on which 1 indicates marked agitation; 2, moderate agitation; 3, mild agitation; 4, normal; 5, mild calmness; 6, moderate calmness; 7, marked calmness; 8, deep sleep; and 9, unable to be aroused. (NCT00797277)
Timeframe: from baseline to 120 minutes after first injection
| Intervention | units on a scale (Mean) |
|---|---|
| 1. IM Olanzapine | 2.14 |
| 2. IM Haloperidol Pus Lorazepam | 2.23 |
The primary efficacy measure was PANSS-EC, which was derived from the PANSS by its originators using a principal-components factor analysis, and includes the items of tension, uncooperativeness, hostility, poor impulse control and excitement.22 The score of each item ranges from 1 (normal) to 7 (most severe), with a total sum score ranging from 5 to 35. The changes in PANSS-EC from baseline to 2 hours after the first injection were compared. (NCT00797277)
Timeframe: from baseline to 120 minutes after first injection
| Intervention | units on a scale (Mean) |
|---|---|
| 1. IM Olanzapine | -10.2 |
| 2. IM Haloperidol Plus Lorazepam | -9.9 |
Minnesota Detoxification Scale (MINDS) min score 0, max score 46. The higher the score, the worse the symptoms of AWS/AWD. (NCT01362205)
Timeframe: up to 28 days
| Intervention | units on a scale (Median) |
|---|---|
| Dexmedetomidine | 8.2 |
| Placebo | 9.4 |
A ventilator day is counted for any use of invasive mechanical ventilation during a calendar day (NCT01362205)
Timeframe: up to 28 days
| Intervention | days (Median) |
|---|---|
| Dexmedetomidine | 27.5 |
| Placebo | 28.0 |
(NCT01362205)
Timeframe: Up to 28 days
| Intervention | USD (Median) |
|---|---|
| Dexmedetomidine | 81234 |
| Placebo | 91651 |
(NCT01362205)
Timeframe: up to 28 Days
| Intervention | Dollar (United States) (Median) |
|---|---|
| Dexmedetomidine | 3482 |
| Placebo | 4461 |
The Beck Anxiety Inventory is a validated questionnaire used to measure severity of anxiety (min score 0, max score 63). The higher the score the greater the severity of anxiety. A score of 30-63 indicates severe anxiety, 17-29 moderate anxiety, 10-16 mild anxiety and 0-9 minimal anxiety. (NCT01362205)
Timeframe: Up to 28 days.
| Intervention | units on a scale (Mean) |
|---|---|
| Dexmedetomidine | 30.3 |
| Placebo | 21.6 |
The Beck Depression Inventory is a validated questionnaire used to measure severity of depression (min score 0, max score 63). The higher the score the greater the severity of depression. A score of 30-63 indicates severe depression, 19-29 moderate depression, 10-18 mild depression and 0-9 minimal depression. (NCT01362205)
Timeframe: Up to 28 days.
| Intervention | units on a scale (Mean) |
|---|---|
| Dexmedetomidine | 26.5 |
| Placebo | 21.4 |
The Mini Mental State Examination or Folstein test is a validated 30-point questionnaire used to measure cognitive impairment (min score 0, max score 30). A score of 24 points (out of a max of 30) indicates normal cognition, less than or equal to 9 points indicates severe impairment, 10-18 indicates moderate impairment and 19-23 mild impairment. (NCT01362205)
Timeframe: up to 28 days
| Intervention | units on a scale (Mean) |
|---|---|
| Dexmedetomidine | 25.8 |
| Placebo | 23.1 |
PTSD checklist consists of 17 questions graded on a scale of 1 to 5. The PTSD score is comprised from the sum of the scores 17 questions. The PTSD score has possible values from to 17 to 85 with higher values indicating greater symptom severity. (NCT01362205)
Timeframe: Up to 28 days
| Intervention | units on a scale (Median) |
|---|---|
| Dexmedetomidine | 45.5 |
| Placebo | 32.5 |
A hospital day is counted for any time on a calendar day the patient is admitted to the hospital. Hospital days are inclusive of ICU days. (NCT01362205)
Timeframe: up to 28 days
| Intervention | days (Median) |
|---|---|
| Dexmedetomidine | 8.0 |
| Placebo | 12.0 |
(NCT01362205)
Timeframe: up to 28 days in hours
| Intervention | hours (Median) |
|---|---|
| Dexmedetomidine | 79.2 |
| Placebo | 104.9 |
The Confusion Assessment Method (CAM)-ICU is a validated instrument used to detect the presence or absence of delirium in the ICU. A delirium free day is counted for any day a patient is negative by the CAM-ICU. The higher the number of CAM-ICU negative days indicates the more days a patient was able to think clearly. (NCT01362205)
Timeframe: up to 28 days
| Intervention | days (Median) |
|---|---|
| Dexmedetomidine | 0.3 |
| Placebo | 0.3 |
15 reviews available for lorazepam and Psychomotor Agitation
| Article | Year |
|---|---|
Psychopharmacology of agitation in acute psychotic and manic episodes.
Topics: Antipsychotic Agents; Benzodiazepines; Drug Therapy, Combination; Haloperidol; Humans; Lorazepam; Ma | 2022 |
The pharmacological management of agitated and aggressive behaviour: A systematic review and meta-analysis.
Topics: Aggression; Anti-Anxiety Agents; Antipsychotic Agents; Benzodiazepines; Drug Therapy, Combination; H | 2019 |
Benzodiazepines for psychosis-induced aggression or agitation.
Topics: Acute Disease; Aggression; Anti-Dyskinesia Agents; Antipsychotic Agents; Benzodiazepines; Drug Thera | 2013 |
Haloperidol plus promethazine for psychosis-induced aggression.
Topics: Aggression; Benzodiazepines; Drug Therapy, Combination; Haloperidol; Humans; Lorazepam; Midazolam; P | 2016 |
Effects of Intramuscular Midazolam and Lorazepam on Acute Agitation in Non-Elderly Subjects - A Systematic Review.
Topics: Anti-Anxiety Agents; Humans; Injections, Intramuscular; Lorazepam; Midazolam; Psychomotor Agitation | 2017 |
Interventions for the treatment of acute agitation.
Topics: Acute Disease; Antipsychotic Agents; Humans; Hypnotics and Sedatives; Lorazepam; Psychomotor Agitati | 2007 |
Haloperidol plus promethazine for psychosis-induced aggression.
Topics: Aggression; Benzodiazepines; Drug Therapy, Combination; Haloperidol; Humans; Lorazepam; Midazolam; O | 2009 |
[Haloperidol plus promethazine for agitated patients--a systematic review].
Topics: Anti-Anxiety Agents; Antipsychotic Agents; Benzodiazepines; Drug Therapy, Combination; Haloperidol; | 2009 |
Efficacy and safety of silexan, a new, orally administered lavender oil preparation, in subthreshold anxiety disorder - evidence from clinical trials.
Topics: Anti-Anxiety Agents; Anxiety Disorders; Humans; Lavandula; Lorazepam; Oils, Volatile; Personality In | 2010 |
Haloperidol for psychosis-induced aggression or agitation (rapid tranquillisation).
Topics: Aggression; Antipsychotic Agents; Aripiprazole; Clopenthixol; Dystonia; Haloperidol; Humans; Lorazep | 2012 |
Haloperidol plus promethazine for psychosis induced aggression.
Topics: Aggression; Drug Therapy, Combination; Haloperidol; Humans; Lorazepam; Midazolam; Promethazine; Psyc | 2005 |
The treatment of acute agitation in schizophrenia.
Topics: Acute Disease; Antipsychotic Agents; Humans; Hypnotics and Sedatives; Lorazepam; Psychomotor Agitati | 2007 |
Pharmacological interventions for agitation in head-injured patients in the acute care setting.
Topics: Adult; Brain Injuries; Critical Care; Dose-Response Relationship, Drug; Drug Administration Schedule | 1995 |
The agitated patient, Part II: Pharmacologic treatment.
Topics: Akathisia, Drug-Induced; Drug Therapy, Combination; Emergencies; Haloperidol; Humans; Lorazepam; Neu | 1993 |
Use of benzodiazepines to control disruptive behavior in inpatients.
Topics: Aggression; Benzodiazepines; Haloperidol; Hospitalization; Humans; Injections, Intramuscular; Loraze | 1988 |
24 trials available for lorazepam and Psychomotor Agitation
| Article | Year |
|---|---|
Efficacy of ketamine for initial control of acute agitation in the emergency department: A randomized study.
Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Dissociative; Anti-Anxiety Agents; Antipsychotic Agents | 2021 |
Randomized Double-blind Trial of Intramuscular Droperidol, Ziprasidone, and Lorazepam for Acute Undifferentiated Agitation in the Emergency Department.
Topics: Antipsychotic Agents; Droperidol; Emergency Service, Hospital; Humans; Hypnotics and Sedatives; Inje | 2021 |
Association among rescue neuroleptic use, agitation, and perceived comfort: secondary analysis of a randomized clinical trial on agitated delirium.
Topics: Antipsychotic Agents; Delirium; Double-Blind Method; Haloperidol; Humans; Lorazepam; Psychomotor Agi | 2021 |
The minimal clinically important difference of the Richmond Agitation-Sedation Scale in patients with cancer with agitated delirium.
Topics: Adult; Aged; Aged, 80 and over; Delirium; Drug Therapy, Combination; Female; Haloperidol; Humans; Lo | 2018 |
Intramuscular olanzapine versus intramuscular haloperidol plus lorazepam for the treatment of acute schizophrenia with agitation: An open-label, randomized controlled trial.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Drug Therapy, Combination; Female; Haloperidol; Humans | 2015 |
Olanzapine versus aripiprazole for the treatment of agitation in acutely ill patients with schizophrenia.
Topics: Acute Disease; Administration, Oral; Adolescent; Adult; Aged; Antipsychotic Agents; Aripiprazole; Be | 2008 |
Calming versus sedative effects of intramuscular olanzapine in agitated patients.
Topics: Adult; Anti-Anxiety Agents; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Dementia; Doubl | 2003 |
Acute treatment of psychotic agitation: a randomized comparison of oral treatment with risperidone and lorazepam versus intramuscular treatment with haloperidol and lorazepam.
Topics: Acute Disease; Administration, Oral; Adolescent; Adult; Aged; Antipsychotic Agents; Cluster Analysis | 2004 |
Efficacy of accelerated dose titration of olanzapine with adjunctive lorazepam to treat acute agitation in schizophrenia.
Topics: Acute Disease; Administration, Oral; Adult; Anti-Anxiety Agents; Antipsychotic Agents; Benzodiazepin | 2004 |
A prospective, double-blind, randomized trial of midazolam versus haloperidol versus lorazepam in the chemical restraint of violent and severely agitated patients.
Topics: Adult; Arousal; Blood Pressure; Double-Blind Method; Haloperidol; Heart Rate; Humans; Lorazepam; Mid | 2004 |
Rapid tranquillisation of violent or agitated patients in a psychiatric emergency setting. Pragmatic randomised trial of intramuscular lorazepam v. haloperidol plus promethazine.
Topics: Antipsychotic Agents; Drug Therapy, Combination; Emergencies; Emergency Service, Hospital; Female; H | 2004 |
Risperidone versus haloperidol, in combination with lorazepam, in the treatment of acute agitation and psychosis: a pilot, randomized, double-blind, placebo-controlled trial.
Topics: Acute Disease; Adolescent; Adult; Aged; Anti-Anxiety Agents; Antipsychotic Agents; Double-Blind Meth | 2006 |
Management of acute agitation in patients with bipolar disorder: efficacy and safety of intramuscular aripiprazole.
Topics: Acute Disease; Adult; Anti-Anxiety Agents; Antipsychotic Agents; Aripiprazole; Bipolar Disorder; Dis | 2007 |
Premedication with orally administered lorazepam in adults undergoing ERCP: a randomized double-blind study.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Cholangiopancreatography, Endoscopic Retrograd | 2007 |
Antidepressant medication treatment failure does not predict lower remission with ECT for major depressive disorder: a report from the consortium for research in electroconvulsive therapy.
Topics: Adult; Antidepressive Agents; Depressive Disorder, Major; Diagnostic and Statistical Manual of Menta | 2007 |
Continuous intravenous infusions of lorazepam versus midazolam for sedation during mechanical ventilatory support: a prospective, randomized study.
Topics: Adult; Clinical Protocols; Conscious Sedation; Critical Care; Female; Fluid Therapy; Humans; Infusio | 1994 |
A double-blind, randomized comparison of the efficacy and safety of intramuscular injections of olanzapine, lorazepam, or placebo in treating acutely agitated patients diagnosed with bipolar mania.
Topics: Adult; Affect; Anti-Anxiety Agents; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Choline | 2001 |
Comparison of rapidly acting intramuscular olanzapine, lorazepam, and placebo: a double-blind, randomized study in acutely agitated patients with dementia.
Topics: Acute Disease; Aged; Anti-Anxiety Agents; Antipsychotic Agents; Benzodiazepines; Dementia; Double-Bl | 2002 |
Adjunctive treatment of manic agitation with lorazepam versus haloperidol: a double-blind study.
Topics: Adult; Aged; Aggression; Bipolar Disorder; Double-Blind Method; Drug Therapy, Combination; Female; H | 1992 |
Agitation in the demented elderly: a role for benzodiazepines?
Topics: Aged; Alprazolam; Dementia; Double-Blind Method; Female; Humans; Lorazepam; Male; Motor Activity; Ps | 1991 |
Use of benzodiazepines.
Topics: Bipolar Disorder; Clinical Trials as Topic; Humans; Lorazepam; Psychomotor Agitation | 1990 |
Efficacy of combinations of intramuscular antipsychotics and sedative-hypnotics for control of psychotic agitation.
Topics: Adolescent; Adult; Drug Combinations; Drug Therapy, Combination; Female; Haloperidol; Humans; Inject | 1989 |
Efficacy of propranolol in neuroleptic-induced akathesia.
Topics: Adult; Akathisia, Drug-Induced; Antipsychotic Agents; Chronic Disease; Female; Humans; Lorazepam; Ma | 1985 |
Treatment of akathisia with lorazepam. An open clinical trial.
Topics: Adult; Akathisia, Drug-Induced; Antipsychotic Agents; Clinical Trials as Topic; Dyskinesia, Drug-Ind | 1987 |
54 other studies available for lorazepam and Psychomotor Agitation
| Article | Year |
|---|---|
Midazolam with haloperidol versus lorazepam with haloperidol for agitation: Effect on emergency department lengths of stay.
Topics: Antipsychotic Agents; Drug Therapy, Combination; Emergency Service, Hospital; Haloperidol; Humans; L | 2022 |
Prospective study of haloperidol plus lorazepam versus droperidol plus midazolam for the treatment of acute agitation in the emergency department.
Topics: Antipsychotic Agents; Droperidol; Emergency Service, Hospital; Haloperidol; Humans; Lorazepam; Midaz | 2022 |
Efficacy of Combination Haloperidol, Lorazepam, and Diphenhydramine vs. Combination Haloperidol and Lorazepam in the Treatment of Acute Agitation: A Multicenter Retrospective Cohort Study.
Topics: Adult; Antipsychotic Agents; Diphenhydramine; Haloperidol; Humans; Hypotension; Lorazepam; Muscarini | 2022 |
Comparison of Droperidol and Midazolam Versus Haloperidol and Lorazepam for Acute Agitation Management in the Emergency Department.
Topics: Antipsychotic Agents; Droperidol; Emergency Service, Hospital; Haloperidol; Humans; Injections, Intr | 2023 |
Brief psychotic disorder with delusion content related to the COVID-19 outbreak.
Topics: Adult; Aggression; Anti-Anxiety Agents; Antipsychotic Agents; COVID-19; Delusions; Humans; Involunta | 2021 |
Paradoxical reaction to benzodiazepines in elderly - Case series.
Topics: Aged; Aggression; Benzodiazepines; Clonazepam; GABA Modulators; Humans; Lorazepam; Male; Psychomotor | 2018 |
Study Enrollment When "Preconsent" Is Utilized for a Randomized Clinical Trial of Two Treatments for Acute Agitation in the Emergency Department.
Topics: Adult; Antipsychotic Agents; Bipolar Disorder; Emergency Service, Hospital; Ethics, Research; Female | 2019 |
Intranasal Lorazepam for Treatment of Severe Agitation in a Pediatric Behavioral Health Patient in the Emergency Department.
Topics: Administration, Intranasal; Anxiety; Attention Deficit and Disruptive Behavior Disorders; Child; Dos | 2020 |
Prevalence and associations of potentially inappropriate prescriptions in Austrian nursing home residents: secondary analysis of a cross-sectional study.
Topics: Adult; Age Distribution; Aged; Austria; Cognition Disorders; Comorbidity; Cross-Sectional Studies; D | 2013 |
Haloperidol overdosing in the treatment of agitated hospitalized older people with delirium: a retrospective chart review from a community teaching hospital.
Topics: Aged; Aged, 80 and over; Aging; Anti-Anxiety Agents; Delirium; Dopamine Antagonists; Dose-Response R | 2013 |
Agitation after minor trauma: combativeness as a cardinal catatonic feature.
Topics: Catatonia; Diagnosis, Differential; Electroencephalography; Female; Humans; Hypnotics and Sedatives; | 2013 |
Stability of intraocular pressure after retinal reattachment surgery during electroconvulsive therapy for intractable self-injury in a 12-year-old autistic boy.
Topics: Aggression; Anticonvulsants; Antipsychotic Agents; Autistic Disorder; Child; Electroconvulsive Thera | 2014 |
Quetiapine reduces irritability and risk of suicide in patients with agitated depression.
Topics: Antipsychotic Agents; Anxiety; Depression; Dibenzothiazepines; Drug Therapy, Combination; Female; Hu | 2013 |
Acute Methylenedioxypyrovalerone Toxicity.
Topics: Adolescent; Adult; Age Factors; Alkaloids; Benzodioxoles; Diagnosis, Dual (Psychiatry); Female; Huma | 2015 |
Discontinuing the Use of PRN Intramuscular Medication for Agitation in an Acute Psychiatric Hospital.
Topics: Administration, Oral; Adult; Diphenhydramine; Drug Utilization; Female; Haloperidol; Hospitals, Psyc | 2016 |
Early percutaneous endoscopic gastrostomy tube dislodgment.
Topics: Accidents, Traffic; Anti-Anxiety Agents; Craniotomy; Enteral Nutrition; Equipment Failure Analysis; | 2015 |
Look again at psychedelic drugs.
Topics: Anxiety; Delirium; Depression; Diazepam; Hallucinogens; Haloperidol; Humans; Lorazepam; Midazolam; P | 2016 |
Valproate for agitation in critically ill patients: A retrospective study.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Delirium; Dexmedetomidine; Female; Fentanyl; GABA | 2017 |
"Stat" medication administration predicts hospital discharge.
Topics: Adult; Antipsychotic Agents; Drug Prescriptions; Female; Hospitals, Psychiatric; Humans; Hypnotics a | 2009 |
You're the flight surgeon: a psychiatric patient in a combat zone.
Topics: Adult; Air Ambulances; Anti-Anxiety Agents; Bipolar Disorder; Humans; Iraq War, 2003-2011; Lorazepam | 2009 |
An intoxicated man with facial trauma.
Topics: Aggression; Alcoholic Intoxication; Anti-Anxiety Agents; Antipsychotic Agents; Emergency Medical Ser | 2010 |
Droperidol use in pediatric emergency department patients.
Topics: Adjuvants, Anesthesia; Adolescent; Anti-Anxiety Agents; Antiemetics; Central Nervous System Depressa | 2010 |
A new clinical protocol for the pharmacological management of acute behavioural disturbance.
Topics: Administration, Oral; Antipsychotic Agents; Benzodiazepines; Clinical Protocols; Humans; Injections, | 2011 |
Bispectral index values, sedation-agitation scores, and plasma Lorazepam concentrations in critically ill surgical patients.
Topics: Adult; Aged; Conscious Sedation; Consciousness Monitors; Critical Illness; Electromyography; Female; | 2012 |
Dexmedetomidine for transport of a spontaneously breathing combative child.
Topics: Child, Preschool; Dexmedetomidine; Humans; Hypnotics and Sedatives; Lorazepam; Male; Mental Disorder | 2012 |
Dexmedetomidine to facilitate drug withdrawal.
Topics: Alcohol Drinking; Blood Pressure; Cocaine-Related Disorders; Dexmedetomidine; Female; Heart Rate; Hu | 2003 |
Agitation by sedation.
Topics: Alcoholism; Antidotes; Chemistry, Pharmaceutical; Ethylene Glycol; Female; Fomepizole; Humans; Hypno | 2003 |
Prolonged dexmedetomidine infusion as an adjunct in treating sedation-induced withdrawal.
Topics: Acinetobacter Infections; Adult; Analgesics, Opioid; Dexmedetomidine; Fentanyl; Humans; Hypnotics an | 2003 |
An unusual case of subterfuge in the emergency department: covert administration of antipsychotic and anxiolytic medications to control an agitated patient.
Topics: Administration, Oral; Adult; Anti-Anxiety Agents; Antipsychotic Agents; Beverages; Bipolar Disorder; | 2006 |
Revisiting cycloid psychosis: a case of an acute, transient and recurring psychotic disorder.
Topics: Acute Disease; Aged; Benzodiazepines; Cognition Disorders; Delusions; Diagnosis, Differential; Diagn | 2006 |
Naturalistic study of intramuscular ziprasidone versus conventional agents in agitated elderly patients: retrospective findings from a psychiatric emergency service.
Topics: Aged; Aged, 80 and over; Antipsychotic Agents; Databases, Factual; Emergency Medical Services; Emerg | 2005 |
Medicating "Margaret".
Topics: Advance Directives; Alzheimer Disease; Analgesics, Opioid; Antipsychotic Agents; Electroconvulsive T | 2006 |
Intramuscular aripiprazole in the control of agitation.
Topics: Adult; Antipsychotic Agents; Aripiprazole; Arousal; Bipolar Disorder; Dose-Response Relationship, Dr | 2007 |
Multiple medication use presenting as Parkinson's dementia complex: a message from Titanic.
Topics: Aged; Anti-Infective Agents; Antiparkinson Agents; Antipsychotic Agents; Bacteriuria; Ciprofloxacin; | 2008 |
Fasciculations after rattlesnake envenomations: a retrospective statewide poison control system study.
Topics: Adolescent; Adult; Animals; Antivenins; Anxiety; California; Child; Child, Preschool; Crotalus; Data | 2008 |
Robert Salter: attempted suicide by jumping from a high bridge.
Topics: Adult; Alcoholism; Anti-Anxiety Agents; Antidepressive Agents; Denial, Psychological; Diagnosis, Dif | 1998 |
Frequency, severity, and treatment of agitation in young versus elderly patients in the ICU.
Topics: Adult; Age Factors; Aged; Analgesics, Opioid; Anti-Anxiety Agents; Antipsychotic Agents; APACHE; Coh | 2000 |
Evaluating the usage of droperidol in acutely agitated persons with brain injury.
Topics: Adult; Antipsychotic Agents; Brain Injuries; Diphenhydramine; Droperidol; Female; Haloperidol; Human | 2000 |
Neuroleptic malignant syndrome precipitated by promethazine and lorazepam.
Topics: Adolescent; Anticonvulsants; Antipsychotic Agents; Basal Ganglia Diseases; Histamine H1 Antagonists; | 2001 |
Risperidone liquid concentrate and oral lorazepam versus intramuscular haloperidol and intramuscular lorazepam for treatment of psychotic agitation.
Topics: Acute Disease; Administration, Oral; Adult; Antipsychotic Agents; Drug Therapy, Combination; Emergen | 2001 |
Failed challenge with quetiapine after neuroleptic malignant syndrome with conventional antipsychotics.
Topics: Alzheimer Disease; Antipsychotic Agents; Chlorpromazine; Dibenzothiazepines; Haloperidol; Humans; Hy | 2001 |
Disinhibition after lorazepam augmentation of antipsychotic medication.
Topics: Adult; Aggression; Antipsychotic Agents; Dose-Response Relationship, Drug; Drug Therapy, Combination | 1991 |
Cocaine intoxication in a 12 month-old.
Topics: Akathisia, Drug-Induced; Cocaine; Fluid Therapy; Humans; Infant; Lorazepam; Male; Poisoning; Psychom | 1991 |
Lorazepam and anticholinergics in tardive akathisia.
Topics: Adult; Akathisia, Drug-Induced; Antipsychotic Agents; Drug Therapy, Combination; Female; Humans; Lor | 1990 |
Benzodiazepine withdrawal syndrome after a benzodiazepine antagonist.
Topics: Adolescent; Akathisia, Drug-Induced; Diazepam; Drug Overdose; Flumazenil; Humans; Injections, Intrav | 1990 |
Lorazepam in the treatment of lithium-induced akathisia.
Topics: Akathisia, Drug-Induced; Bipolar Disorder; Drug Therapy, Combination; Humans; Lithium; Lithium Carbo | 1989 |
Propranolol and clonidine in detoxification.
Topics: Clonidine; Humans; Lorazepam; Methadone; Opioid-Related Disorders; Propranolol; Psychomotor Agitatio | 1988 |
Lorazepam and manic agitation.
Topics: Adult; Bipolar Disorder; Humans; Lorazepam; Male; Myocardial Infarction; Psychomotor Agitation | 1986 |
Lorazepam for the treatment of psychotic agitation.
Topics: Adult; Aggression; Humans; Injections, Intramuscular; Lorazepam; Male; Psychomotor Agitation; Schizo | 1986 |
Further experience and observations with lorazepam in the management of behavioral agitation.
Topics: Dose-Response Relationship, Drug; Humans; Lorazepam; Psychomotor Agitation; Referral and Consultatio | 1986 |
Benzodiazepines combined with neuroleptics for management of severe disruptive behavior.
Topics: Adolescent; Adult; Aged; Dangerous Behavior; Drug Therapy, Combination; Female; Haloperidol; Hospita | 1986 |
Alternative approaches in the treatment of psychotic agitation.
Topics: Combined Modality Therapy; Haloperidol; Humans; Injections, Intramuscular; Lorazepam; Psychomotor Ag | 1986 |
Acute treatment of manic agitation with lorazepam.
Topics: Acute Disease; Bipolar Disorder; Humans; Injections, Intramuscular; Lorazepam; Psychomotor Agitation | 1986 |
Emergency treatment of acute psychosis, agitation, and anxiety.
Topics: Anxiety Disorders; Diazepam; Droperidol; Emergencies; Haloperidol; Humans; Lorazepam; Panic; Propran | 1985 |