lorazepam has been researched along with Pregnancy in 49 studies
Lorazepam: A benzodiazepine used as an anti-anxiety agent with few side effects. It also has hypnotic, anticonvulsant, and considerable sedative properties and has been proposed as a preanesthetic agent.
Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Intrathecal morphine can produce hypothermia in animals." | 7.73 | Hypothermia after cesarean delivery and its reversal with lorazepam. ( Hess, PE; Snowman, CE; Wang, J, 2005) |
| "The authors report five new cases of catatonia; three patients responded favorably and two failed to respond to lorazepam." | 6.37 | Lorazepam treatment of psychogenic catatonia: an update. ( Kilzieh, N; Salam, SA, 1988) |
| " Given her undifferentiated headache and the possibility of preeclampsia, the patient was treated with magnesium sulfate, which was subsequently stopped due to worsening bradycardia." | 3.81 | Late Postpartum Eclampsia with Postpartum Angiopathy: An Uncommon Diagnosis in the Emergency Department. ( Dickman, E; Garg, D; Rahaman, B; Stein, EG, 2015) |
| "Intrathecal morphine can produce hypothermia in animals." | 3.73 | Hypothermia after cesarean delivery and its reversal with lorazepam. ( Hess, PE; Snowman, CE; Wang, J, 2005) |
| "QUESTIONOne of my patients suffers from anxiety and was using lorazepam to treat it." | 3.70 | Can we use anxiolytics during pregnancy without anxiety? ( Addis, A; Dolovich, LR; Einarson, TR; Koren, G, 2000) |
| "Lorazepam enantiomers were determined in plasma and urine samples by LC-MS/MS using a Chiralcel OD-R column." | 2.72 | Kinetic disposition of lorazepam with focus on the glucuronidation capacity, transplacental transfer in parturients and racemization in biological samples. ( Bertucci, C; da Cunha, SP; da Silva Mathes, Ado C; de Barros Duarte, L; de Carvalho Cavalli, R; Lanchote, VL; Moisés, EC; Papini, O, 2006) |
| "Lorazepam did produce a transient effect on the neonatal respiratory rate and initially the babies had a reduced score on the Brazelton Assessment System." | 2.65 | Use of lorazepam as a premedicant for caesarean section. An evaluation of its effects on the mother and the neonate. ( Houghton, DJ, 1983) |
| "The authors report five new cases of catatonia; three patients responded favorably and two failed to respond to lorazepam." | 2.37 | Lorazepam treatment of psychogenic catatonia: an update. ( Kilzieh, N; Salam, SA, 1988) |
| "Knowledge of the pharmacokinetic properties of the benzodiazepines is playing an increasingly important role in their use during pregnancy, labour and lactation." | 2.36 | Use of benzodiazepines during pregnancy, labour and lactation, with particular reference to pharmacokinetic considerations. ( Kanto, JH, 1982) |
| " Naloxone 2 mg by gastric tube every 8 hours for 8 days was started; the dosage then was increased to 4 mg every 8 hours." | 1.32 | Enteral administration of naloxone for treatment of opioid-associated intragastric feeding intolerance. ( Bloom, K; Liebl, MG; Mixides, G, 2004) |
| "Lorazepam is a new member of a constantly growing benzodiazepine family." | 1.26 | Lorazepam-related withdrawal seizures. ( de la Fuente, JR; Martin, HR; Niven, RG; Rosenbaum, AH, 1980) |
| "Lorazepam was an effective sedative and anxiolytic by either route, and there were no eclamptic fits among the lorazepam-treated patients." | 1.26 | Effect of maternal lorazepam on the neonate. ( Cummings, AJ; McFadyen, IR; Whitelaw, AG, 1981) |
| "Lorazepam and diazepam were both unsatisfactory as sedatives for patients having Caesarean Section." | 1.26 | Lorazepam and diazepam as adjuncts to epidural anaesthesia for caesarean section. ( Cumming, M; Ong, BY; Palahniuk, RJ; Pickering, BG, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 25 (51.02) | 18.7374 |
| 1990's | 11 (22.45) | 18.2507 |
| 2000's | 11 (22.45) | 29.6817 |
| 2010's | 1 (2.04) | 24.3611 |
| 2020's | 1 (2.04) | 2.80 |
| Authors | Studies |
|---|---|
| Uguz, F | 1 |
| Kirkas, A | 1 |
| Aksoy, ZK | 1 |
| Yunden, S | 1 |
| Garg, D | 1 |
| Rahaman, B | 1 |
| Stein, EG | 1 |
| Dickman, E | 1 |
| Martínez-Lage, JF | 1 |
| Almagro, MJ | 1 |
| López Hernández, F | 1 |
| Poza, M | 1 |
| Wiebe, E | 1 |
| Podhradsky, L | 1 |
| Dijak, V | 1 |
| Mixides, G | 1 |
| Liebl, MG | 1 |
| Bloom, K | 1 |
| Papini, O | 2 |
| da Cunha, SP | 1 |
| da Silva Mathes, Ado C | 1 |
| Bertucci, C | 2 |
| Moisés, EC | 1 |
| de Barros Duarte, L | 1 |
| de Carvalho Cavalli, R | 1 |
| Lanchote, VL | 2 |
| Hess, PE | 1 |
| Snowman, CE | 1 |
| Wang, J | 1 |
| da Cunha, SP | 1 |
| Dos Santos, NA | 1 |
| Allen, RH | 1 |
| Kumar, D | 1 |
| Fitzmaurice, G | 1 |
| Lifford, KL | 1 |
| Goldberg, AB | 1 |
| Kwon, P | 1 |
| Lefkowitz, W | 1 |
| de la Fuente, JR | 1 |
| Rosenbaum, AH | 1 |
| Martin, HR | 1 |
| Niven, RG | 1 |
| Girkin, R | 2 |
| Baldock, GA | 1 |
| Chasseaud, LF | 2 |
| Hümpel, M | 2 |
| Hawkins, DR | 2 |
| Mayo, BC | 2 |
| Kanto, J | 1 |
| Aaltonen, L | 1 |
| Liukko, P | 1 |
| Mäenpää, K | 1 |
| Whitelaw, AG | 2 |
| Cummings, AJ | 2 |
| McFadyen, IR | 1 |
| Johnstone, M | 1 |
| Ong, BY | 1 |
| Pickering, BG | 1 |
| Palahniuk, RJ | 1 |
| Cumming, M | 1 |
| McAuley, DM | 1 |
| O'Neill, MP | 1 |
| Moore, J | 3 |
| Dundee, JW | 3 |
| Kanto, JH | 1 |
| Johnstone, MJ | 1 |
| Houghton, DJ | 1 |
| Olive, G | 1 |
| Rey, E | 1 |
| Koff, JM | 1 |
| Miller, LG | 5 |
| Finnerty, M | 1 |
| Levin, Z | 1 |
| Miller, LJ | 1 |
| Tsen, LC | 1 |
| Datta, S | 1 |
| Addis, A | 1 |
| Dolovich, LR | 1 |
| Einarson, TR | 1 |
| Koren, G | 2 |
| Einarson, A | 1 |
| Selby, P | 1 |
| Bonnot, O | 1 |
| Vollset, SE | 1 |
| Godet, PF | 1 |
| D'Amato, T | 1 |
| Robert, E | 1 |
| Barr, AM | 1 |
| Moxon, A | 1 |
| Woollam, CH | 1 |
| Fryer, ME | 1 |
| Braestrup, C | 1 |
| Nielsen, M | 1 |
| Squires, RF | 1 |
| McBride, RJ | 2 |
| Toner, W | 2 |
| Howard, PJ | 2 |
| Crawford, JS | 1 |
| Cobo, MS | 1 |
| Ramírez, CT | 1 |
| Bonet, HM | 1 |
| Laegreid, L | 1 |
| Hagberg, G | 1 |
| Lundberg, A | 1 |
| Shurtz-Swirski, R | 1 |
| Cohen, Y | 1 |
| Barnea, ER | 1 |
| Chesley, S | 2 |
| Lumpkin, M | 1 |
| Schatzki, A | 1 |
| Galpern, WR | 2 |
| Greenblatt, DJ | 2 |
| Shader, RI | 2 |
| Hakkarinen, WD | 1 |
| Sanchis, A | 1 |
| Rosique, D | 1 |
| Catala, J | 1 |
| Trachtenberg, D | 1 |
| Dencker, SJ | 1 |
| Johansson, G | 1 |
| Roy, RB | 2 |
| Weill, CL | 2 |
| Lopez, F | 1 |
| Fioretti, P | 1 |
| Melis, GB | 1 |
| Gambacciani, M | 1 |
| Galbani, P | 1 |
| Ronca-Testoni, S | 1 |
| Salam, SA | 1 |
| Kilzieh, N | 1 |
| Scottez, B | 1 |
| Peutillot, A | 1 |
| Summerfield, RJ | 1 |
| Nielsen, MS | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Double-blind, Randomized, Placebo-controlled Study on the Effect of Multimodal Analgesia on Pain With Insertion of Levonorgestrel-releasing Intrauterine System[NCT02799641] | 61 participants (Actual) | Interventional | 2016-07-31 | Completed | |||
| An Evaluation of Hydrocodone/Acetaminophen for Pain Control in First Trimester Surgical Abortion[NCT01330459] | Phase 4 | 121 participants (Actual) | Interventional | 2011-02-28 | Completed | ||
| Oral Sedation During Cervical Dilator Placement: A Randomized Controlled Trial[NCT03202550] | Phase 4 | 27 participants (Actual) | Interventional | 2017-06-28 | Completed | ||
| An Evaluation of the Paracervical Block for Pain Control in First Trimester Surgical Abortion[NCT01094366] | Phase 4 | 121 participants (Actual) | Interventional | 2010-04-30 | Completed | ||
| A Prospective, Randomized Trial of Enteral Naloxone Versus a Traditional Bowel Regimen in Prevention of Constipation and Decreased Gastric Motility in Critically Ill Trauma Patients[NCT00799201] | Phase 4 | 3 participants (Actual) | Interventional | 2007-08-31 | Terminated (stopped due to Naloxone became unavailable due to manufacturing shortatges requiring the study to be terminated.) | ||
| The Effect Of Forced Air Warming Used For Different Body Parts During Caseraen Section On Maternal Hypothermia, Shivering, Thermal Comfort, Apgar Score And Breastfeeding: Randomized Controlled Trial[NCT04667000] | 35 participants (Anticipated) | Interventional | 2021-05-01 | Active, not recruiting | |||
| Auricular Acupuncture as Adjunct for Pain Management During First Trimester Uterine Aspiration.[NCT03391986] | 153 participants (Actual) | Interventional | 2017-09-09 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
To assess need for additional intraoperative and/or postoperative pain medication (NCT01330459)
Timeframe: 30 minutes after completion of the procedure (which started 45-90 minutes after study drug administration)
| Intervention | Participants (Count of Participants) |
|---|---|
| Hydrocodone/Acetaminophen | 0 |
| Placebo | 0 |
To determine whether HC/APAP, given in addition to a standard regimen of ibuprofen, lorazepam, and PCB, affects patient pain perception at the time of uterine aspiration, as measured by distance (mm) from the left of the 100 mm visual analog scale (VAS). The number 0 indicates no pain, and 100 indicates worst pain imaginable. (NCT01330459)
Timeframe: At time of uterine aspiration (baseline)
| Intervention | mm (Mean) |
|---|---|
| Hydrocodone/Acetaminophen | 65.7 |
| Placebo | 63.1 |
Distance (mm) from the left of the 100 mm VAS scale (VAS anchors: 0 = none, 100 mm = worst imaginable) recorded after cervical dilation (NCT01330459)
Timeframe: During procedure (approximately 45-90 min after hydrocodone/acetaminophen or placebo, and within 5 minutes of procedure starting)
| Intervention | mm (Mean) |
|---|---|
| Hydrocodone/Acetaminophen | 47.2 |
| Placebo | 43.9 |
To assess whether HC/APAP is associated with nausea, measured on the 100 mm VAS, recorded 30 minutes postoperatively. VAS anchors: 0 indicates no pain, and 100 indicates worst pain imaginable. (NCT01330459)
Timeframe: 30 minutes after completion of the procedure (which started 45-90 minutes after study drug administration)
| Intervention | mm (Mean) |
|---|---|
| Hydrocodone/Acetaminophen | 19.4 |
| Placebo | 11.4 |
Distance (mm) from the left of the 100 mm VAS (VAS anchors: 0 = unsatisfied, 100 mm = very satisfied) recorded 30 minutes after completion of the procedure. (NCT01330459)
Timeframe: 30 minutes after completion of the procedure (which started 45-90 minutes after study drug administration)
| Intervention | mm (Mean) |
|---|---|
| Hydrocodone/Acetaminophen | 74.8 |
| Placebo | 67.3 |
Compare pain scores on a 100 mm visual analog scale (VAS) (anchors 0=no pain; 100=worst pain ever) (NCT03202550)
Timeframe: pain score given prior to administration of study drugs, up to 1 minute
| Intervention | units on a scale (Median) |
|---|---|
| Placebo Arm | 3 |
| Active Drug Arm: Lorazepam and Oxycodone | 2 |
Compare pain scores on a 100 mm visual analog scale (VAS) (anchors 0=no pain; 100=worst pain ever) (NCT03202550)
Timeframe: Immediately after the last dilator is placed, up to 1 minute
| Intervention | units on a scale (Median) |
|---|---|
| Placebo Arm | 55 |
| Active Drug Arm: Lorazepam and Oxycodone | 44 |
Assess whether desired number of dilators was not able to be successfully inserted, comparing 2 arms. (NCT03202550)
Timeframe: After speculum removed, up to 30 minutes
| Intervention | Participants (Count of Participants) |
|---|---|
| Placebo Arm | 13 |
| Active Drug Arm: Lorazepam and Oxycodone | 10 |
Compare pain scores on a 100 mm visual analog scale (VAS) (anchors 0=no pain; 100=worst pain ever). This was to be assessed at 15 minutes after last dilator is placed. Some participants had this assessment done up to 45 minutes after last dilator was placed because it could not be done at 15 minutes (some were being attended to by a nurse at the 15 minutes mark). (NCT03202550)
Timeframe: Assessed up to 45 minutes after last dilator placed
| Intervention | units on a scale (Median) |
|---|---|
| Placebo Arm | 29 |
| Active Drug Arm: Lorazepam and Oxycodone | 13 |
Compare pain scores on a 100 mm visual analog scale (VAS) (anchors 0=no pain; 100=worst pain ever) (NCT03202550)
Timeframe: pain score given immediately after first dilator placed, up to 1 minute
| Intervention | units on a scale (Median) |
|---|---|
| Placebo Arm | 50 |
| Active Drug Arm: Lorazepam and Oxycodone | 9 |
Compare pain scores on a 100 mm visual analog scale (VAS) (anchors 0=no pain; 100=worst pain ever) (NCT03202550)
Timeframe: pain score given at time of speculum placement, up to 1 minute
| Intervention | units on a scale (Median) |
|---|---|
| Placebo Arm | 20 |
| Active Drug Arm: Lorazepam and Oxycodone | 11 |
Compare pain scores on a 100 mm visual analog scale (VAS) (anchors 0=no pain; 100=worst pain ever) (NCT03202550)
Timeframe: Immediately scored at time of tenacula placement, up to 1 minute
| Intervention | units on a scale (Median) |
|---|---|
| Placebo Arm | 31 |
| Active Drug Arm: Lorazepam and Oxycodone | 50 |
Compare pain scores on a 100 mm visual analog scale (VAS) (anchors 0=no pain; 100=worst pain ever) (NCT03202550)
Timeframe: pain score given before specula placed, up to 1 minute
| Intervention | units on a scale (Median) |
|---|---|
| Placebo Arm | 1 |
| Active Drug Arm: Lorazepam and Oxycodone | 1 |
Compare pain scores on a 100 mm visual analog scale (VAS) (anchors 0=no pain; 100=worst pain ever) (NCT03202550)
Timeframe: pain score given at time of paracervical block administration, up to 1 minute
| Intervention | units on a scale (Median) |
|---|---|
| Placebo Arm | 57 |
| Active Drug Arm: Lorazepam and Oxycodone | 51 |
Measure effectiveness of placebo as an adjunct to ibuprofen and paracervical block for pain control during uterine aspiration by comparing the maximum pain score; as measured by VAS between women randomized to receive placebo adhesives and routine care controls - using a 100 mm visual analog scale (VAS-P) (anchors: 0 mm = no pain, 100 mm = worst pain in my life). (NCT03391986)
Timeframe: prior to the procedure (baseline), at the completion of the procedure (approximately 10 minutes later)
| Intervention | score on a scale (Mean) |
|---|---|
| Placebo Adhesives | 70.0 |
| Routine Care | 71.0 |
Using a satisfaction survey (investigator-developed, 6 questions, each question is graded on a scale of 1-5, 1 being very poor and 5 being very good) to measure effectiveness of auricular acupuncture for improving satisfaction. (NCT03391986)
Timeframe: at the completion of the procedure (approximately 5-10 minutes)
| Intervention | percentage of participants (Number) |
|---|---|
| Pyonex Needles | 94 |
| Routine Care | 76 |
Measure effectiveness of auricular acupuncture as an adjunct to ibuprofen and paracervical block for pain control during first trimester uterine aspiration by comparing the maximum pain score; as measured by VAS between women randomized to receive auricular acupuncture and routine care controls - using a 100 mm visual analog scale (VAS-P) (anchors: 0 mm = no pain, 100 mm = worst pain in my life). The VAS has no sub-scales. (NCT03391986)
Timeframe: at the completion of the procedure (approximately 10 minutes later)
| Intervention | score on a scale (Mean) |
|---|---|
| Pyonex Needles | 39.5 |
| Routine Care | 71.0 |
3 reviews available for lorazepam and Pregnancy
| Article | Year |
|---|---|
Use of benzodiazepines during pregnancy, labour and lactation, with particular reference to pharmacokinetic considerations.
Topics: Anti-Anxiety Agents; Chlordiazepoxide; Clorazepate Dipotassium; Diazepam; Female; Flunitrazepam; Hum | 1982 |
[Benzodiazepines and pregnancy. Transplacental passage, labor and lactation].
Topics: Anti-Anxiety Agents; Biotransformation; Chlordiazepoxide; Clorazepate Dipotassium; Diazepam; Female; | 1983 |
Lorazepam treatment of psychogenic catatonia: an update.
Topics: Adult; Aged; Anemia, Pernicious; Catatonia; Female; Humans; Lorazepam; Male; Middle Aged; Pregnancy; | 1988 |
8 trials available for lorazepam and Pregnancy
| Article | Year |
|---|---|
The effect of lorazepam on pain and anxiety in abortion.
Topics: Abortion, Induced; Adult; Anti-Anxiety Agents; Anxiety; Double-Blind Method; Female; Humans; Lorazep | 2003 |
The effect of lorazepam on pain and anxiety in abortion.
Topics: Abortion, Induced; Adult; Anti-Anxiety Agents; Anxiety; Double-Blind Method; Female; Humans; Lorazep | 2003 |
The effect of lorazepam on pain and anxiety in abortion.
Topics: Abortion, Induced; Adult; Anti-Anxiety Agents; Anxiety; Double-Blind Method; Female; Humans; Lorazep | 2003 |
The effect of lorazepam on pain and anxiety in abortion.
Topics: Abortion, Induced; Adult; Anti-Anxiety Agents; Anxiety; Double-Blind Method; Female; Humans; Lorazep | 2003 |
The effect of lorazepam on pain and anxiety in abortion.
Topics: Abortion, Induced; Adult; Anti-Anxiety Agents; Anxiety; Double-Blind Method; Female; Humans; Lorazep | 2003 |
The effect of lorazepam on pain and anxiety in abortion.
Topics: Abortion, Induced; Adult; Anti-Anxiety Agents; Anxiety; Double-Blind Method; Female; Humans; Lorazep | 2003 |
The effect of lorazepam on pain and anxiety in abortion.
Topics: Abortion, Induced; Adult; Anti-Anxiety Agents; Anxiety; Double-Blind Method; Female; Humans; Lorazep | 2003 |
The effect of lorazepam on pain and anxiety in abortion.
Topics: Abortion, Induced; Adult; Anti-Anxiety Agents; Anxiety; Double-Blind Method; Female; Humans; Lorazep | 2003 |
The effect of lorazepam on pain and anxiety in abortion.
Topics: Abortion, Induced; Adult; Anti-Anxiety Agents; Anxiety; Double-Blind Method; Female; Humans; Lorazep | 2003 |
The effect of lorazepam on pain and anxiety in abortion.
Topics: Abortion, Induced; Adult; Anti-Anxiety Agents; Anxiety; Double-Blind Method; Female; Humans; Lorazep | 2003 |
The effect of lorazepam on pain and anxiety in abortion.
Topics: Abortion, Induced; Adult; Anti-Anxiety Agents; Anxiety; Double-Blind Method; Female; Humans; Lorazep | 2003 |
The effect of lorazepam on pain and anxiety in abortion.
Topics: Abortion, Induced; Adult; Anti-Anxiety Agents; Anxiety; Double-Blind Method; Female; Humans; Lorazep | 2003 |
The effect of lorazepam on pain and anxiety in abortion.
Topics: Abortion, Induced; Adult; Anti-Anxiety Agents; Anxiety; Double-Blind Method; Female; Humans; Lorazep | 2003 |
The effect of lorazepam on pain and anxiety in abortion.
Topics: Abortion, Induced; Adult; Anti-Anxiety Agents; Anxiety; Double-Blind Method; Female; Humans; Lorazep | 2003 |
The effect of lorazepam on pain and anxiety in abortion.
Topics: Abortion, Induced; Adult; Anti-Anxiety Agents; Anxiety; Double-Blind Method; Female; Humans; Lorazep | 2003 |
The effect of lorazepam on pain and anxiety in abortion.
Topics: Abortion, Induced; Adult; Anti-Anxiety Agents; Anxiety; Double-Blind Method; Female; Humans; Lorazep | 2003 |
Kinetic disposition of lorazepam with focus on the glucuronidation capacity, transplacental transfer in parturients and racemization in biological samples.
Topics: Adolescent; Adult; Anti-Anxiety Agents; Chromatography, Liquid; Female; Fetal Blood; Gestational Age | 2006 |
Quantitative assay of lorazepam and its metabolite glucuronide by reverse-phase liquid chromatography-tandem mass spectrometry in human plasma and urine samples.
Topics: Acetonitriles; Anti-Anxiety Agents; Chromatography, Liquid; Drug Stability; Female; Humans; Lorazepa | 2006 |
Lorazepam premedication for labour.
Topics: Adolescent; Adult; Anti-Anxiety Agents; Clinical Trials as Topic; Double-Blind Method; Female; Human | 1982 |
The effect of lorazepam on neonatal feeding behaviour at term.
Topics: Anti-Anxiety Agents; Bottle Feeding; Feeding Behavior; Female; Humans; Infant, Newborn; Labor, Obste | 1982 |
Use of lorazepam as a premedicant for caesarean section. An evaluation of its effects on the mother and the neonate.
Topics: Anti-Anxiety Agents; Anxiety; Apgar Score; Blood Gas Analysis; Body Temperature; Cesarean Section; F | 1983 |
The effect of diazepam and lorazepam on awareness during anaesthesia for Caesarian section.
Topics: Adult; Anesthesia, General; Anesthesia, Obstetrical; Anti-Anxiety Agents; Awareness; Cesarean Sectio | 1977 |
Premedication for elective Caesarean section.
Topics: Anesthesia, Epidural; Anesthesia, General; Anesthesia, Obstetrical; Anti-Anxiety Agents; Apgar Score | 1979 |
38 other studies available for lorazepam and Pregnancy
| Article | Year |
|---|---|
Use of Psychotropic Medication During Lactation in Postpartum Psychiatric Patients: Results from an 8-Year Clinical Sample.
Topics: Adult; Breast Feeding; Female; Humans; Lactation; Lorazepam; Mental Disorders; Postpartum Period; Pr | 2020 |
Late Postpartum Eclampsia with Postpartum Angiopathy: An Uncommon Diagnosis in the Emergency Department.
Topics: Adult; Anticonvulsants; Antihypertensive Agents; Drug Therapy, Combination; Eclampsia; Emergency Ser | 2015 |
Aplasia cutis congenita of the scalp.
Topics: Abnormalities, Drug-Induced; Chlordiazepoxide; Female; Humans; Infant, Newborn; Lorazepam; Male; Mat | 2002 |
Enteral administration of naloxone for treatment of opioid-associated intragastric feeding intolerance.
Topics: Adult; Catheters, Indwelling; Cross Infection; Drug Administration Schedule; Enteral Nutrition; Fata | 2004 |
Hypothermia after cesarean delivery and its reversal with lorazepam.
Topics: Adult; Analgesics, Opioid; Anesthesia, Obstetrical; Anesthesia, Spinal; Anesthetics, Local; Bupivaca | 2005 |
Pain management of first-trimester surgical abortion: effects of selection of local anesthesia with and without lorazepam or intravenous sedation.
Topics: Abortion, Induced; Adult; Analgesia; Anesthetics; Female; Fentanyl; Humans; Ibuprofen; Lorazepam; Mi | 2006 |
Pain management of first-trimester surgical abortion: effects of selection of local anesthesia with and without lorazepam or intravenous sedation.
Topics: Abortion, Induced; Adult; Analgesia; Anesthetics; Female; Fentanyl; Humans; Ibuprofen; Lorazepam; Mi | 2006 |
Pain management of first-trimester surgical abortion: effects of selection of local anesthesia with and without lorazepam or intravenous sedation.
Topics: Abortion, Induced; Adult; Analgesia; Anesthetics; Female; Fentanyl; Humans; Ibuprofen; Lorazepam; Mi | 2006 |
Pain management of first-trimester surgical abortion: effects of selection of local anesthesia with and without lorazepam or intravenous sedation.
Topics: Abortion, Induced; Adult; Analgesia; Anesthetics; Female; Fentanyl; Humans; Ibuprofen; Lorazepam; Mi | 2006 |
Pain management of first-trimester surgical abortion: effects of selection of local anesthesia with and without lorazepam or intravenous sedation.
Topics: Abortion, Induced; Adult; Analgesia; Anesthetics; Female; Fentanyl; Humans; Ibuprofen; Lorazepam; Mi | 2006 |
Pain management of first-trimester surgical abortion: effects of selection of local anesthesia with and without lorazepam or intravenous sedation.
Topics: Abortion, Induced; Adult; Analgesia; Anesthetics; Female; Fentanyl; Humans; Ibuprofen; Lorazepam; Mi | 2006 |
Pain management of first-trimester surgical abortion: effects of selection of local anesthesia with and without lorazepam or intravenous sedation.
Topics: Abortion, Induced; Adult; Analgesia; Anesthetics; Female; Fentanyl; Humans; Ibuprofen; Lorazepam; Mi | 2006 |
Pain management of first-trimester surgical abortion: effects of selection of local anesthesia with and without lorazepam or intravenous sedation.
Topics: Abortion, Induced; Adult; Analgesia; Anesthetics; Female; Fentanyl; Humans; Ibuprofen; Lorazepam; Mi | 2006 |
Pain management of first-trimester surgical abortion: effects of selection of local anesthesia with and without lorazepam or intravenous sedation.
Topics: Abortion, Induced; Adult; Analgesia; Anesthetics; Female; Fentanyl; Humans; Ibuprofen; Lorazepam; Mi | 2006 |
Neonatal extrapyramidal movements. Neonatal withdrawal due to maternal citalopram and ondansetron use.
Topics: Adult; Anti-Anxiety Agents; Basal Ganglia Diseases; Citalopram; Female; Humans; Infant, Newborn; Lor | 2008 |
Lorazepam-related withdrawal seizures.
Topics: Adult; Anti-Anxiety Agents; Epilepsy, Tonic-Clonic; Female; Humans; Lorazepam; Pregnancy; Pregnancy | 1980 |
The absorption, distribution and excretion of [14C]lormetazepam in dogs, rabbits, rats and rhesus monkeys.
Topics: Absorption; Animals; Anti-Anxiety Agents; Benzodiazepines; Carbon Radioisotopes; Dogs; Female; Loraz | 1980 |
The biotransformation of [14C]lormetazepam in dogs, rabbits, rats and rhesus monkeys.
Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; Bile; Biotransformation; Carbon Radioisotopes; Chroma | 1980 |
Transfer of lorazepam and its conjugate across the human placenta.
Topics: Adult; Amniotic Fluid; Anti-Anxiety Agents; Female; Humans; Lorazepam; Maternal-Fetal Exchange; Preg | 1980 |
Effect of maternal lorazepam on the neonate.
Topics: Anti-Anxiety Agents; Apgar Score; Body Temperature; Female; Fetal Blood; Humans; Hypertension; Infan | 1981 |
Effect of maternal lorazepam on the neonate.
Topics: Anti-Anxiety Agents; Feeding Behavior; Female; Humans; Infant, Newborn; Lorazepam; Maternal-Fetal Ex | 1981 |
A study of conjugation and drug elimination in the human neonate.
Topics: Anti-Anxiety Agents; Female; Humans; Hypertension; Infant, Newborn; Lorazepam; Male; Maternal-Fetal | 1981 |
Lorazepam and diazepam as adjuncts to epidural anaesthesia for caesarean section.
Topics: Adult; Anesthesia, Epidural; Anesthesia, Obstetrical; Anti-Anxiety Agents; Anxiety; Blood Pressure; | 1982 |
Prenatal lorazepam exposure: 4. Persistent alterations in pentylenetetrazole-induced seizure threshold and GABA-dependent chloride uptake after prenatal lorazepam exposure.
Topics: Animals; Brain Chemistry; Chlorides; Chlorine; Female; gamma-Aminobutyric Acid; Lorazepam; Mice; Mus | 1995 |
Acute manic episodes in pregnancy.
Topics: Adult; Bipolar Disorder; Chlorpromazine; Comorbidity; Diabetes Mellitus, Type 1; Drug Therapy, Combi | 1996 |
Panic attacks and lactated Ringer's solution: is there a relationship?
Topics: Adult; Analgesia, Epidural; Anesthetics, Local; Diagnostic Errors; Female; Humans; Isotonic Solution | 1999 |
Can we use anxiolytics during pregnancy without anxiety?
Topics: Anti-Anxiety Agents; Anxiety; Cleft Palate; Female; Humans; Infant, Newborn; Lorazepam; Practice Gui | 2000 |
Discontinuing antidepressants and benzodiazepines upon becoming pregnant. Beware of the risks of abrupt discontinuation.
Topics: Anti-Anxiety Agents; Antidepressive Agents; Evidence-Based Medicine; Female; Humans; Informed Consen | 2001 |
Maternal exposure to lorazepam and anal atresia in newborns: results from a hypothesis-generating study of benzodiazepines and malformations.
Topics: Abnormalities, Drug-Induced; Adult; Anti-Anxiety Agents; Anus, Imperforate; Databases, Factual; Fema | 2001 |
No changes in rat benzodiazepine receptors after withdrawal from continuous treatment with lorazepam and diazepam.
Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; Diazepam; Female; Humans; Kinetics; Lorazepam; Male; | 1979 |
Placental transfer of lorazepam [proceedings].
Topics: Anti-Anxiety Agents; Female; Humans; Lorazepam; Maternal-Fetal Exchange; Pregnancy | 1979 |
A study of the plasma concentrations of lorazepam in mother and neonate.
Topics: Adult; Anesthesia, Obstetrical; Anti-Anxiety Agents; Apgar Score; Female; Fetal Blood; Humans; Infan | 1979 |
[Use of Lorazepam in the menopause, sterility, frigidity and obesity].
Topics: Anti-Anxiety Agents; Drug Evaluation; Female; Humans; Infertility, Female; Lorazepam; Menopause; Obe | 1975 |
Neurodevelopment in late infancy after prenatal exposure to benzodiazepines--a prospective study.
Topics: Abnormalities, Drug-Induced; Anti-Anxiety Agents; Arousal; Body Height; Body Weight; Cephalometry; D | 1992 |
Patterns of secretion of human chorionic gonadotrophin by superfused placental explants and the embryo--placental relationship following maternal use of medications.
Topics: Chorionic Gonadotropin; Codeine; Diclofenac; Female; Humans; Lorazepam; Maternal-Fetal Exchange; Org | 1992 |
Prenatal exposure to benzodiazepine--I. Prenatal exposure to lorazepam in mice alters open-field activity and GABAA receptor function.
Topics: Animals; Brain; Cerebral Cortex; Chlorides; Female; Gestational Age; Lorazepam; Maternal-Fetal Excha | 1991 |
Prenatal benzodiazepine administration. II. Lorazepam exposure is associated with decreases in [35S]TBPS binding but not benzodiazepine binding.
Topics: Animals; Body Weight; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Female; Lo | 1991 |
A safe treatment for hyperemesis gravidarum?
Topics: Contraindications; Female; Humans; Hyperemesis Gravidarum; Injections; Lorazepam; Pregnancy | 1992 |
Adverse effects of maternal lorazepam on neonates.
Topics: Female; Humans; Infant, Newborn; Lorazepam; Male; Maternal-Fetal Exchange; Nystagmus, Pathologic; Pn | 1991 |
Hyperemesis gravidarum treated with lorazepam.
Topics: Adult; Female; Humans; Hyperemesis Gravidarum; Lorazepam; Pregnancy; Recurrence | 1991 |
Benzodiazepine-like substances in mother's milk.
Topics: Animals; Benzodiazepines; Female; Humans; Infant, Newborn; Lorazepam; Milk, Human; Pregnancy; Recept | 1990 |
Persistent alterations in GABAA receptor binding and function after prenatal lorazepam administration in the chick.
Topics: Animals; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Chick Embryo; Chickens; | 1989 |
Prenatal lorazepam administration is associated with GABAA receptor alterations in late embryonic and mature chicks.
Topics: Animals; Brain Chemistry; Chick Embryo; Chickens; Female; Lorazepam; Pregnancy; Prenatal Exposure De | 1989 |
Evidence of specific benzodiazepine binding to myometrial membrane preparations from human pregnant uterus.
Topics: Adult; Benzodiazepines; Benzodiazepinones; Cell Membrane; Chlordiazepoxide; Diazepam; Female; Flunit | 1986 |
[Temesta].
Topics: Aged; Anxiety; Depressive Disorder; Female; Humans; Lorazepam; Male; Pregnancy | 1985 |
Excretion of lorazepam into breast milk.
Topics: Female; Humans; Infant, Newborn; Lorazepam; Milk, Human; Postpartum Period; Preanesthetic Medication | 1985 |