lorazepam has been researched along with Precursor Cell Lymphoblastic Leukemia-Lymphoma in 6 studies
Lorazepam: A benzodiazepine used as an anti-anxiety agent with few side effects. It also has hypnotic, anticonvulsant, and considerable sedative properties and has been proposed as a preanesthetic agent.
Precursor Cell Lymphoblastic Leukemia-Lymphoma: A neoplasm characterized by abnormalities of the lymphoid cell precursors leading to excessive lymphoblasts in the marrow and other organs. It is the most common cancer in children and accounts for the vast majority of all childhood leukemias.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Nausea was observed in 51/71 patients (72%) and 93/164 cycles (57%)." | 5.51 | Impact of adjuvant lorazepam with granisetron on chemotherapy-induced nausea and vomiting in pediatric patients with acute lymphoblastic leukemia. ( Goldman, RD; Hasegawa, D; Kishimoto, K; Kosaka, Y; Ono, A, 2019) |
| "Nausea was observed in 51/71 patients (72%) and 93/164 cycles (57%)." | 1.51 | Impact of adjuvant lorazepam with granisetron on chemotherapy-induced nausea and vomiting in pediatric patients with acute lymphoblastic leukemia. ( Goldman, RD; Hasegawa, D; Kishimoto, K; Kosaka, Y; Ono, A, 2019) |
| "Oral lorazepam was tolerated by the patients, but all patients needed dose reduction due to some adverse effects." | 1.36 | Oral lorazepam prevents seizure during high-dose busulfan in children undergoing hematopoietic stem cell transplantation: a prospective study. ( Amini, M; Ghavamzadeh, A; Hadjibabaie, M; Hamedani, R; Hamidieh, AA; Sadrai, S, 2010) |
| "4 ml/min/kg, with a terminal half-life of 10." | 1.28 | Lorazepam pharmacodynamics and pharmacokinetics in children. ( Dodge, RK; Evans, WE; Johnson, D; Mulhern, RK; Pieper, JA; Relling, MV; Rivera, GK, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (16.67) | 18.7374 |
| 1990's | 2 (33.33) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ono, A | 1 |
| Kishimoto, K | 1 |
| Hasegawa, D | 1 |
| Goldman, RD | 1 |
| Kosaka, Y | 1 |
| Hamidieh, AA | 1 |
| Hamedani, R | 1 |
| Hadjibabaie, M | 1 |
| Amini, M | 1 |
| Sadrai, S | 1 |
| Ghavamzadeh, A | 1 |
| Relling, MV | 3 |
| Mulhern, RK | 2 |
| Fairclough, D | 1 |
| Baker, D | 1 |
| Pui, CH | 1 |
| Pelletier, G | 1 |
| Lacroix, Y | 1 |
| Moghrabi, A | 1 |
| Robaey, P | 1 |
| Crom, WR | 1 |
| Christensen, ML | 1 |
| Rivera, GK | 2 |
| Evans, WE | 2 |
| Dodge, RK | 1 |
| Johnson, D | 1 |
| Pieper, JA | 1 |
2 trials available for lorazepam and Precursor Cell Lymphoblastic Leukemia-Lymphoma
| Article | Year |
|---|---|
Chlorpromazine with and without lorazepam as antiemetic therapy in children receiving uniform chemotherapy.
Topics: Adolescent; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Ch | 1993 |
Double-blind crossover study of chlorpromazine and lorazepam in the treatment of behavioral problems during treatment of children with acute lymphoblastic leukaemia receiving glucocorticoids.
Topics: Anti-Anxiety Agents; Antipsychotic Agents; Child; Child Behavior; Child Behavior Disorders; Chlorpro | 2000 |
4 other studies available for lorazepam and Precursor Cell Lymphoblastic Leukemia-Lymphoma
| Article | Year |
|---|---|
Impact of adjuvant lorazepam with granisetron on chemotherapy-induced nausea and vomiting in pediatric patients with acute lymphoblastic leukemia.
Topics: Adjuvants, Pharmaceutic; Adolescent; Adrenal Cortex Hormones; Anthracyclines; Antiemetics; Antineopl | 2019 |
Oral lorazepam prevents seizure during high-dose busulfan in children undergoing hematopoietic stem cell transplantation: a prospective study.
Topics: Administration, Oral; Adolescent; Anticonvulsants; Busulfan; Child; Child, Preschool; Dose-Response | 2010 |
Age-related differences in hepatic drug clearance in children: studies with lorazepam and antipyrine.
Topics: Adolescent; Adult; Age Factors; Antipyrine; Body Weight; Child; Child, Preschool; Female; Humans; In | 1991 |
Lorazepam pharmacodynamics and pharmacokinetics in children.
Topics: Adolescent; Attention; Child; Child, Preschool; Emotions; Humans; Lorazepam; Memory; Metabolic Clear | 1989 |