lorazepam has been researched along with Panic Attacks in 16 studies
Lorazepam: A benzodiazepine used as an anti-anxiety agent with few side effects. It also has hypnotic, anticonvulsant, and considerable sedative properties and has been proposed as a preanesthetic agent.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The authors report on seven consecutive openly treated patients with panic disorder who showed inadequate antipanic responses to treatment regimens including either a tricyclic (TCA) or fluoxetine." | 7.69 | Augmentation strategies with tricyclic or fluoxetine treatment in seven partially responsive panic disorder patients. ( Coplan, JD; Gorman, JM; Papp, LA; Tiffon, L, 1994) |
| "Panic attacks were defined using the panic symptom scale (PSS)." | 6.76 | One milligram of lorazepam does not decrease anxiety induced by CCK-4 in healthy volunteers: investigation of neural correlates with BOLD MRI. ( Demazières, A; Erb, G; Hode, Y; Luthringer, R; Mathis, A; Namer, IJ; Schunck, T, 2011) |
| "The authors report on seven consecutive openly treated patients with panic disorder who showed inadequate antipanic responses to treatment regimens including either a tricyclic (TCA) or fluoxetine." | 3.69 | Augmentation strategies with tricyclic or fluoxetine treatment in seven partially responsive panic disorder patients. ( Coplan, JD; Gorman, JM; Papp, LA; Tiffon, L, 1994) |
| "In the treatment of panic disorder double-blind controlled studies have demonstrated that imipramine (IMI) was effective at doses higher than 125 mg/day." | 3.69 | The treatment of panic disorder in a clinical setting: a 12-month naturalistic study. ( Ampollini, P; Maggini, C; Marchesi, C; Signifredi, R, 1997) |
| "Panic attacks were defined using the panic symptom scale (PSS)." | 2.76 | One milligram of lorazepam does not decrease anxiety induced by CCK-4 in healthy volunteers: investigation of neural correlates with BOLD MRI. ( Demazières, A; Erb, G; Hode, Y; Luthringer, R; Mathis, A; Namer, IJ; Schunck, T, 2011) |
| "Clonazepam has several advantages over other benzodiazepines and can be considered a first-line agent for panic disorder." | 2.40 | Use of benzodiazepines in panic disorder. ( Davidson, JR, 1997) |
| "Three patients had exceptionally high seizure threshold, as determined by an empirical titration procedure." | 1.29 | Exceptionally high seizure threshold: ECT device limitations. ( Devanand, DP; Lisanby, SH; Mullen, L; Nobler, MS; Prudic, J; Sackeim, HA, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 9 (56.25) | 18.2507 |
| 2000's | 5 (31.25) | 29.6817 |
| 2010's | 1 (6.25) | 24.3611 |
| 2020's | 1 (6.25) | 2.80 |
| Authors | Studies |
|---|---|
| Uvais, NA | 1 |
| Schunck, T | 1 |
| Mathis, A | 1 |
| Erb, G | 1 |
| Namer, IJ | 1 |
| Hode, Y | 1 |
| Demazières, A | 1 |
| Luthringer, R | 2 |
| Watanabe, T | 1 |
| Ueda, M | 1 |
| Saeki, Y | 1 |
| Hirokane, G | 1 |
| Morita, S | 1 |
| Okawa, M | 1 |
| Akiyama, K | 1 |
| Shimoda, K | 1 |
| Gilles, C | 1 |
| Marchesi, C | 2 |
| De Panfilis, C | 1 |
| Cantoni, A | 1 |
| Giannelli, MR | 1 |
| Maggini, C | 2 |
| Clivaz, E | 1 |
| Chauvet, I | 1 |
| Zullino, D | 1 |
| Niquille, M | 1 |
| Maris, S | 1 |
| Cicotti, A | 1 |
| Lazignac, C | 1 |
| Lazignac Coralie, C | 1 |
| Damsa, C | 1 |
| Chung, CK | 1 |
| Remington, ND | 1 |
| Suh, BY | 1 |
| Robinson, D | 1 |
| Casso, DE | 1 |
| Omar, SJ | 1 |
| Tinklenberg, JR | 1 |
| Cohen, SI | 1 |
| Tiffon, L | 1 |
| Coplan, JD | 1 |
| Papp, LA | 1 |
| Gorman, JM | 1 |
| Lisanby, SH | 1 |
| Devanand, DP | 1 |
| Nobler, MS | 1 |
| Prudic, J | 1 |
| Mullen, L | 1 |
| Sackeim, HA | 1 |
| Davidson, JR | 1 |
| Ampollini, P | 1 |
| Signifredi, R | 1 |
| Maltsberger, JT | 1 |
| Tsen, LC | 1 |
| Datta, S | 1 |
| Kopp, M | 1 |
| Holzner, B | 1 |
| Brugger, A | 1 |
| Nachbaur, D | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effect of Bupropion on Seizure Threshold in Depressed Patients[NCT03126682] | Phase 4 | 10 participants (Actual) | Interventional | 2017-08-25 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Scoring of depressive symptoms on the Montgomery Asberg Depression Rating Scale, maximum 60 , minimum 0. Higher scores mean worse outcome. First measurement on day 1 of electroconvulsive treatment (ECT) and second measurement on day 2 of electroconvulsive therapy (ECT), separated by 1 day interval. This outcome measure was not measured at baseline. (NCT03126682)
Timeframe: Scored on day 1 and day 2 after ECT session
| Intervention | Scored on a scale (Mean) |
|---|---|
| Wellbutrin During ECT 1 | 2.60 |
| Wellbutrin During ECT 2 | 3.60 |
Duration of seizures with ECT. First measurement on day 1 of electroconvulsive treatment (ECT) and second measurement on day 2 of electroconvulsive therapy (ECT), separated by 1 day interval. This outcome measure was not measured at baseline. (NCT03126682)
Timeframe: Measured at day 1 and day 2
| Intervention | seconds (Mean) |
|---|---|
| Wellbutrin During ECT 1 | 26.2 |
| Wellbutrin During ECT 2 | 29.6 |
Charge in Millicoulombs at which subject gets a seizure with ECT. First measurement on day 1 of electroconvulsive treatment (ECT) and second measurement on day 2 of electroconvulsive therapy (ECT), separated by 1 day interval. This outcome measure was not measured at baseline. (NCT03126682)
Timeframe: Measured at day 1 and day 2
| Intervention | millicoulombs (Mean) |
|---|---|
| Wellbutrin During ECT 1 | 23.04 |
| Wellbutrin During ECT 2 | 19.68 |
2 reviews available for lorazepam and Panic Attacks
| Article | Year |
|---|---|
Pharmacological models in healthy volunteers: their use in the clinical development of psychotropic drugs.
Topics: Apomorphine; Cognition Disorders; Dopamine Agonists; Excitatory Amino Acid Antagonists; GABA Modulat | 2007 |
Use of benzodiazepines in panic disorder.
Topics: Alprazolam; Benzodiazepines; Clonazepam; Humans; Lorazepam; Panic Disorder; Treatment Outcome | 1997 |
3 trials available for lorazepam and Panic Attacks
| Article | Year |
|---|---|
One milligram of lorazepam does not decrease anxiety induced by CCK-4 in healthy volunteers: investigation of neural correlates with BOLD MRI.
Topics: Adult; Anti-Anxiety Agents; Anxiety; Anxiety Disorders; Attention; Cerebral Cortex; Cross-Over Studi | 2011 |
High plasma concentrations of paroxetine impede clinical response in patients with panic disorder.
Topics: Adult; Aged; Antidepressive Agents, Second-Generation; Asian People; Azepines; Diagnostic and Statis | 2007 |
Effect of pharmacological treatment on temperament and character in panic disorder.
Topics: Adult; Anxiety; Character; Citalopram; Female; Follow-Up Studies; GABA Modulators; Humans; Lorazepam | 2008 |
11 other studies available for lorazepam and Panic Attacks
| Article | Year |
|---|---|
Psychological Impact of the COVID-19 Pandemic Among the Elderly: A Case Series From India.
Topics: Acetamides; Aged; Aged, 80 and over; Anti-Anxiety Agents; Antidepressive Agents; Betacoronavirus; Ci | 2020 |
Topiramate and panic attacks in patients with borderline personality disorder.
Topics: Adolescent; Anti-Anxiety Agents; Borderline Personality Disorder; Emergency Medical Services; Female | 2008 |
Estrogen replacement therapy may reduce panic symptoms.
Topics: Adult; Amitriptyline; Drug Therapy, Combination; Estradiol; Estrogen Replacement Therapy; Estrogens, | 1995 |
Possible oral lactate exacerbation of panic disorder.
Topics: Administration, Oral; Adult; Drug Synergism; Female; Humans; Lactates; Lactic Acid; Lorazepam; Panic | 1995 |
Alcohol and benzodiazepines generate anxiety, panic and phobias.
Topics: Adult; Aged; Alcohol Drinking; Alcoholism; Anti-Anxiety Agents; Anxiety Disorders; Diazepam; Female; | 1995 |
Augmentation strategies with tricyclic or fluoxetine treatment in seven partially responsive panic disorder patients.
Topics: Adult; Alprazolam; Antidepressive Agents, Tricyclic; Desipramine; Drug Therapy, Combination; Female; | 1994 |
Exceptionally high seizure threshold: ECT device limitations.
Topics: Aged; Aged, 80 and over; Anti-Anxiety Agents; Bipolar Disorder; Depressive Disorder; Electroconvulsi | 1996 |
The treatment of panic disorder in a clinical setting: a 12-month naturalistic study.
Topics: Agoraphobia; Anti-Anxiety Agents; Antidepressive Agents, Tricyclic; Arousal; Dose-Response Relations | 1997 |
Robert Salter: attempted suicide by jumping from a high bridge.
Topics: Adult; Alcoholism; Anti-Anxiety Agents; Antidepressive Agents; Denial, Psychological; Diagnosis, Dif | 1998 |
Panic attacks and lactated Ringer's solution: is there a relationship?
Topics: Adult; Analgesia, Epidural; Anesthetics, Local; Diagnostic Errors; Female; Humans; Isotonic Solution | 1999 |
Successful management of claustrophobia and depression during allogeneic SCT.
Topics: Adult; Anti-Anxiety Agents; Anxiety; Cognitive Behavioral Therapy; Combined Modality Therapy; Cranio | 2001 |