lorazepam has been researched along with Obesity in 5 studies
Lorazepam: A benzodiazepine used as an anti-anxiety agent with few side effects. It also has hypnotic, anticonvulsant, and considerable sedative properties and has been proposed as a preanesthetic agent.
Obesity: A status with BODY WEIGHT that is grossly above the recommended standards, usually due to accumulation of excess FATS in the body. The standards may vary with age, sex, genetic or cultural background. In the BODY MASS INDEX, a BMI greater than 30.0 kg/m2 is considered obese, and a BMI greater than 40.0 kg/m2 is considered morbidly obese (MORBID OBESITY).
| Excerpt | Relevance | Reference |
|---|---|---|
| "The influence of obesity on the distribution or clearance of lorazepam and oxazepam, two benzodiazepines biotransformed by glucuronide conjugation, was studied in a series of obese subjects (mean weight 113 kg; mean percent IBW 179%) and healthy controls of normal body habitus matched for age and sex." | 7.66 | Enhanced glucuronide conjugation of drugs in obesity: studies of lorazepam, oxazepam, and acetaminophen. ( Abernethy, DR; Divoll, M; Greenblatt, DJ; Shader, RI, 1983) |
| " The objectives of this study were to assess the need for weight considerations in dosing antipsychotics and benzodiazepines for patients with agitation and to assess prescribing patterns in agitated patients." | 1.91 | Prescribing Practices for Agitation Medication in Obese Patients Admitted to the Emergency Department. ( Butala, N; Kang, C; Williams, A, 2023) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (40.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kang, C | 1 |
| Williams, A | 1 |
| Butala, N | 1 |
| Barnhorst, A | 1 |
| Xiong, GL | 1 |
| Abernethy, DR | 1 |
| Greenblatt, DJ | 1 |
| Divoll, M | 1 |
| Shader, RI | 1 |
| Buczko, GB | 1 |
| Cobo, MS | 1 |
| RamÃrez, CT | 1 |
| Bonet, HM | 1 |
1 review available for lorazepam and Obesity
| Article | Year |
|---|---|
Sedation in critically ill patients: a review.
Topics: Adult; Age Factors; Aged; Analgesics; Critical Illness; Electroencephalography; Humans; Hypnotics an | 2001 |
4 other studies available for lorazepam and Obesity
| Article | Year |
|---|---|
Prescribing Practices for Agitation Medication in Obese Patients Admitted to the Emergency Department.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Chlorpromazine; Emergency Service, Hospital; Humans; L | 2023 |
Pulmonary embolism in a psychiatric patient.
Topics: Adult; Aggression; Antipsychotic Agents; Autopsy; Benzodiazepines; Bipolar Disorder; Catatonia; Deat | 2014 |
Enhanced glucuronide conjugation of drugs in obesity: studies of lorazepam, oxazepam, and acetaminophen.
Topics: Acetaminophen; Adult; Aged; Anti-Anxiety Agents; Female; Glucuronates; Humans; Lorazepam; Male; Midd | 1983 |
[Use of Lorazepam in the menopause, sterility, frigidity and obesity].
Topics: Anti-Anxiety Agents; Drug Evaluation; Female; Humans; Infertility, Female; Lorazepam; Menopause; Obe | 1975 |