Page last updated: 2024-10-30

lorazepam and Muscle Spasticity

lorazepam has been researched along with Muscle Spasticity in 3 studies

Lorazepam: A benzodiazepine used as an anti-anxiety agent with few side effects. It also has hypnotic, anticonvulsant, and considerable sedative properties and has been proposed as a preanesthetic agent.

Muscle Spasticity: A form of muscle hypertonia associated with upper MOTOR NEURON DISEASE. Resistance to passive stretch of a spastic muscle results in minimal initial resistance (a free interval) followed by an incremental increase in muscle tone. Tone increases in proportion to the velocity of stretch. Spasticity is usually accompanied by HYPERREFLEXIA and variable degrees of MUSCLE WEAKNESS. (From Adams et al., Principles of Neurology, 6th ed, p54)

Research Excerpts

ExcerptRelevanceReference
"Dogs, surgically implanted with a chronic gastric fistula, were chronically dosed with N-desmethyldiazepam (32 mg/kg/day) in four divided doses to attain N-desmethyldiazepam plasma levels comparable to those observed in dogs dependent on diazepam (60 mg/kg/day)."1.27N-desmethyldiazepam physical dependence in dogs. ( Martin, WR; McNicholas, LF; Pruitt, TA, 1985)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19901 (33.33)18.7374
1990's0 (0.00)18.2507
2000's1 (33.33)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Manjunatha, N1
Mehta, UM1
John, P1
West, PL1
Hendrickson, RG1
McNicholas, LF1
Martin, WR1
Pruitt, TA1

Other Studies

3 other studies available for lorazepam and Muscle Spasticity

ArticleYear
Recurrent opisthotonus in catatonia: An atypical presentation.
    Indian journal of medical sciences, 2009, Volume: 63, Issue:11

    Topics: Adult; Catatonia; Diagnosis, Differential; Dystonia; Electroconvulsive Therapy; GABA Modulators; Hum

2009
After the fall: a teenager with unusual intermittent muscle spasms.
    Pediatric emergency care, 2011, Volume: 27, Issue:3

    Topics: Accidental Falls; Adolescent; Anticonvulsants; Diagnosis, Differential; Humans; Injections, Intraven

2011
N-desmethyldiazepam physical dependence in dogs.
    The Journal of pharmacology and experimental therapeutics, 1985, Volume: 235, Issue:2

    Topics: Analysis of Variance; Animals; Body Weight; Diazepam; Dogs; Drinking; Energy Intake; Female; Lorazep

1985