Page last updated: 2024-10-30

lorazepam and MELAS Syndrome

lorazepam has been researched along with MELAS Syndrome in 1 studies

Lorazepam: A benzodiazepine used as an anti-anxiety agent with few side effects. It also has hypnotic, anticonvulsant, and considerable sedative properties and has been proposed as a preanesthetic agent.

MELAS Syndrome: A mitochondrial disorder characterized by focal or generalized seizures, episodes of transient or persistent neurologic dysfunction resembling strokes, and ragged-red fibers on muscle biopsy. Affected individuals tend to be normal at birth through early childhood, then experience growth failure, episodic vomiting, and recurrent cerebral insults resulting in visual loss and hemiparesis. The cortical lesions tend to occur in the parietal and occipital lobes and are not associated with vascular occlusion. VASCULAR HEADACHE is frequently associated and the disorder tends to be familial. (From Joynt, Clinical Neurology, 1992, Ch56, p117)

Research Excerpts

ExcerptRelevanceReference
"A 41-year-old Caucasian female with MELAS syndrome, presenting with short stature, microcytic anaemia, increased blood-sedimentation rate, myopathy, hyper-gammaglobulinaemia, an iron-metabolism defect, migraine-like headaches, and stroke-like episodes, developed complex partial and generalised seizures at age 32 years."1.36Regression of stroke-like lesions in MELAS-syndrome after seizure control. ( Barton, P; Finsterer, J, 2010)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Finsterer, J1
Barton, P1

Other Studies

1 other study available for lorazepam and MELAS Syndrome

ArticleYear
Regression of stroke-like lesions in MELAS-syndrome after seizure control.
    Epileptic disorders : international epilepsy journal with videotape, 2010, Volume: 12, Issue:4

    Topics: Adult; Anticonvulsants; Cerebral Cortex; Diagnosis, Differential; Electroencephalography; Female; Hu

2010