lorazepam has been researched along with Long Sleeper Syndrome in 28 studies
Lorazepam: A benzodiazepine used as an anti-anxiety agent with few side effects. It also has hypnotic, anticonvulsant, and considerable sedative properties and has been proposed as a preanesthetic agent.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Delirium and daily dosage of lorazepam are the factors independently associated to extremely severe REM sleep reduction." | 3.77 | Sleep disturbances in the critically ill patients: role of delirium and sedative agents. ( Bosma, K; Braghiroli, A; Locane, MD; Mascia, L; Ranieri, VM; Trompeo, AC; Vidi, Y, 2011) |
| " The exposure to noise significantly prolonged tmax (control vs." | 2.79 | The effect of experimentally induced sleep disturbance on the pharmacokinetics of lorazepam in healthy volunteers. ( Imai, H; Kotegawa, T; Nakano, S; Ohashi, K; Tsutsumi, K, 2014) |
| " Adverse reactions were evenly distributed among the LMZ and placebo treatment periods and were usually minor." | 2.65 | Double-blind evaluation of the safety and hypnotic efficacy of lormetazepam in general practice. ( Camera, A; Gherardi, S; Maxia, D; Moja, EA; Scamonatti, L, 1983) |
| "Finally, seizure-like nonepileptic disorders were reviewed and differential diagnostic points highlighted." | 2.36 | Seizures and seizure-like states in the child: an approach to emergency management. ( Oppenheimer, EY; Rosman, NP, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 17 (60.71) | 18.7374 |
| 1990's | 5 (17.86) | 18.2507 |
| 2000's | 1 (3.57) | 29.6817 |
| 2010's | 5 (17.86) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Reddy, MSS | 1 |
| Achary, U | 1 |
| Harbishettar, V | 1 |
| Sivakumar, PT | 1 |
| Varghese, M | 1 |
| Kotegawa, T | 1 |
| Tsutsumi, K | 1 |
| Imai, H | 1 |
| Ohashi, K | 1 |
| Nakano, S | 1 |
| Watson, PL | 1 |
| Trompeo, AC | 1 |
| Vidi, Y | 1 |
| Locane, MD | 1 |
| Braghiroli, A | 1 |
| Mascia, L | 1 |
| Bosma, K | 1 |
| Ranieri, VM | 1 |
| Verster, JC | 1 |
| Roth, T | 1 |
| Hentschel, HD | 1 |
| Sastre y Hernández, M | 1 |
| Fichte, K | 4 |
| Fernández Labriola, R | 1 |
| Satre y Hernández, M | 1 |
| Doom, A | 1 |
| Ibarra, M | 1 |
| Mundeleer, P | 1 |
| Bruwier, M | 1 |
| Sastre-y-Hernández, M | 2 |
| Vass, K | 1 |
| Paschelke, G | 1 |
| Pöldinger, W | 1 |
| Moja, EA | 1 |
| Scamonatti, L | 1 |
| Maxia, D | 1 |
| Camera, A | 1 |
| Gherardi, S | 1 |
| Ananth, J | 1 |
| Van den Steen, N | 1 |
| Hill, RC | 1 |
| Harry, TV | 1 |
| Oppenheimer, EY | 1 |
| Rosman, NP | 1 |
| Hertrich, O | 1 |
| Adam, K | 1 |
| Oswald, I | 1 |
| Ohayon, MM | 1 |
| Caulet, M | 1 |
| Nolen, WA | 1 |
| Haffmans, PM | 1 |
| Bouvy, PF | 1 |
| Duivenvoorden, HJ | 1 |
| Klimke, A | 1 |
| Klieser, E | 1 |
| Malcolm, R | 1 |
| Myrick, H | 1 |
| Roberts, J | 1 |
| Wang, W | 1 |
| Anton, RF | 1 |
| Sechzer, PH | 1 |
| Dubnitskaia, EB | 1 |
| Basov, AM | 1 |
| Richards, DJ | 1 |
| Feder, R | 1 |
| D'Hoore, W | 1 |
| Allen, RM | 1 |
| Meco, G | 1 |
| Lestingi, L | 1 |
| Barbieri, MR | 1 |
| Bove, R | 1 |
| Maltese, A | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Impact of Night-time Dexmedetomidine-esketamine Infusion on Sleep Quality of Patients With Mechanical Ventilation in ICU: a Randomized Controlled Trial[NCT05718024] | Phase 4 | 174 participants (Anticipated) | Interventional | 2023-12-31 | Not yet recruiting | ||
| Impact of Dexmedetomidine Supplemented Analgesia on Sleep Quality in Elderly Patients After Major Surgery: A Randomized, Double-blind, and Placebo-controlled Pilot Study[NCT03117790] | Phase 4 | 118 participants (Actual) | Interventional | 2017-06-26 | Completed | ||
| Impact of Low-Dose Dexmedetomidine on Sleep Quality in Mechanical Ventilation Patients After Surgery in Intensive Care Unit: a Pilot Randomized, Double-Blind, Placebo-Controlled Trial[NCT03335527] | Phase 4 | 80 participants (Actual) | Interventional | 2017-11-17 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for lorazepam and Long Sleeper Syndrome
| Article | Year |
|---|---|
Gender differences in highway driving performance after administration of sleep medication: a review of the literature.
Topics: Acetamides; Automobile Driving; Azabicyclo Compounds; Environment Design; Female; Flurazepam; Humans | 2012 |
Seizures and seizure-like states in the child: an approach to emergency management.
Topics: Anesthesia, General; Child; Child, Preschool; Diagnosis, Differential; Diazepam; Emergencies; Humans | 1983 |
13 trials available for lorazepam and Long Sleeper Syndrome
| Article | Year |
|---|---|
The effect of experimentally induced sleep disturbance on the pharmacokinetics of lorazepam in healthy volunteers.
Topics: Administration, Oral; Adult; Area Under Curve; Chromatography, High Pressure Liquid; Cross-Over Stud | 2014 |
[Lormetazepam in the treatment of sleep disorders in a medical practice; double-blind test on 100 patients (author's transl)].
Topics: Adult; Aged; Anti-Anxiety Agents; Benzodiazepines; Diazepam; Double-Blind Method; Female; Humans; Lo | 1981 |
[Comparison of lormetazepam, flunitrazepam and placebo in a long-term effect and long-term tolerance study in 105 patients with chronic sleep disorders].
Topics: Adult; Anti-Anxiety Agents; Benzodiazepines; Clinical Trials as Topic; Drug Tolerance; Female; Fluni | 1981 |
[Drug therapy of sleep disorders in shift workers].
Topics: Adolescent; Adult; Anti-Anxiety Agents; Benzodiazepines; Clinical Trials as Topic; Double-Blind Meth | 1982 |
Study with lormetazepam as a hypnotic in general practice.
Topics: Adolescent; Adult; Aged; Ambulatory Care; Anti-Anxiety Agents; Benzodiazepines; Family Practice; Fem | 1983 |
Double-blind evaluation of the safety and hypnotic efficacy of lormetazepam in general practice.
Topics: Adolescent; Adult; Anti-Anxiety Agents; Benzodiazepines; Clinical Trials as Topic; Double-Blind Meth | 1983 |
Intramuscular lorazepam. A double-blind comparison with diazepam and placebo.
Topics: Adolescent; Adult; Anxiety Disorders; Clinical Trials as Topic; Diazepam; Double-Blind Method; Femal | 1983 |
Lormetazepam (Lorámet): a multicentre assessment of its efficacy and acceptability as a hypnotic in out-patients with sleep disturbances.
Topics: Administration, Oral; Adolescent; Adult; Aged; Anti-Anxiety Agents; Benzodiazepines; Clinical Trials | 1983 |
Hypnotics as concurrent medication in depression. A placebo-controlled, double-blind comparison of flunitrazepam and lormetazepam in patients with major depression, treated with a (tri)cyclic antidepressant.
Topics: Adult; Anti-Anxiety Agents; Antidepressive Agents, Tricyclic; Benzodiazepines; Depressive Disorder; | 1993 |
The differential effects of medication on mood, sleep disturbance, and work ability in outpatient alcohol detoxification.
Topics: Adult; Affect; Alcoholism; Anti-Anxiety Agents; Anticonvulsants; Anxiety; Carbamazepine; Double-Blin | 2002 |
Demand method evaluation of hypnotics.
Topics: Adolescent; Adult; Aged; Anti-Anxiety Agents; Dose-Response Relationship, Drug; Drug Evaluation; Fem | 1976 |
[Use of phenazepam in the treatment of neurotic conditions].
Topics: Adult; Affective Symptoms; Anti-Anxiety Agents; Benzodiazepines; Chemical Phenomena; Chemistry; Clin | 1978 |
A double-blind controlled subjective study of a new pharmaceutical preparation of lormetazepam versus placebo in patients with chronic sleep disturbances.
Topics: Adult; Aged; Anti-Anxiety Agents; Benzodiazepines; Clinical Trials as Topic; Double-Blind Method; Hu | 1985 |
13 other studies available for lorazepam and Long Sleeper Syndrome
| Article | Year |
|---|---|
Paradoxical reaction to benzodiazepines in elderly - Case series.
Topics: Aged; Aggression; Benzodiazepines; Clonazepam; GABA Modulators; Humans; Lorazepam; Male; Psychomotor | 2018 |
Sleep in the ICU: where dreams go to die.
Topics: Delirium; Female; Humans; Hypnotics and Sedatives; Lorazepam; Male; Sleep Wake Disorders | 2011 |
Sleep disturbances in the critically ill patients: role of delirium and sedative agents.
Topics: Aged; Critical Illness; Delirium; Female; Humans; Hypnotics and Sedatives; Lorazepam; Male; Middle A | 2011 |
Sleep disturbances in the critically ill patients: role of delirium and sedative agents.
Topics: Aged; Critical Illness; Delirium; Female; Humans; Hypnotics and Sedatives; Lorazepam; Male; Middle A | 2011 |
Sleep disturbances in the critically ill patients: role of delirium and sedative agents.
Topics: Aged; Critical Illness; Delirium; Female; Humans; Hypnotics and Sedatives; Lorazepam; Male; Middle A | 2011 |
Sleep disturbances in the critically ill patients: role of delirium and sedative agents.
Topics: Aged; Critical Illness; Delirium; Female; Humans; Hypnotics and Sedatives; Lorazepam; Male; Middle A | 2011 |
Sleep disturbances in the critically ill patients: role of delirium and sedative agents.
Topics: Aged; Critical Illness; Delirium; Female; Humans; Hypnotics and Sedatives; Lorazepam; Male; Middle A | 2011 |
Sleep disturbances in the critically ill patients: role of delirium and sedative agents.
Topics: Aged; Critical Illness; Delirium; Female; Humans; Hypnotics and Sedatives; Lorazepam; Male; Middle A | 2011 |
Sleep disturbances in the critically ill patients: role of delirium and sedative agents.
Topics: Aged; Critical Illness; Delirium; Female; Humans; Hypnotics and Sedatives; Lorazepam; Male; Middle A | 2011 |
Sleep disturbances in the critically ill patients: role of delirium and sedative agents.
Topics: Aged; Critical Illness; Delirium; Female; Humans; Hypnotics and Sedatives; Lorazepam; Male; Middle A | 2011 |
Sleep disturbances in the critically ill patients: role of delirium and sedative agents.
Topics: Aged; Critical Illness; Delirium; Female; Humans; Hypnotics and Sedatives; Lorazepam; Male; Middle A | 2011 |
Pre- and postoperative use of lormetazepam.
Topics: Anti-Anxiety Agents; Benzodiazepines; Bone and Bones; Double-Blind Method; Dreams; Female; Humans; L | 1981 |
[Clinical study of lormetazepam (WY-4082) in patients at a geriatric hospital].
Topics: Aged; Anti-Anxiety Agents; Benzodiazepines; Double-Blind Method; Drug Evaluation; Female; Humans; Hy | 1981 |
[Ataractic treatment in psychiatry and general medicine. Review of preparations. 9].
Topics: Adjustment Disorders; Anthracenes; Anti-Anxiety Agents; Benzodiazepines; Humans; Lorazepam; Maprotil | 1983 |
Effects of lormetazepam and of flurazepam on sleep.
Topics: Aged; Anti-Anxiety Agents; Benzodiazepines; Double-Blind Method; Female; Flurazepam; Half-Life; Huma | 1984 |
Insomnia and psychotropic drug consumption.
Topics: Adolescent; Adult; Age Distribution; Aged; Anxiety; Benzodiazepines; Bromazepam; Female; Humans; Lor | 1995 |
Sudden death after intravenous application of lorazepam in a patient treated with clozapine.
Topics: Adult; Clozapine; Death, Sudden; Drug Interactions; Drug Therapy, Combination; Humans; Injections, I | 1994 |
Clinical profile of lorazepam, a new benzodiazepine tranquilizer.
Topics: Administration, Oral; Adolescent; Adult; Age Factors; Aged; Anti-Anxiety Agents; Anxiety; Anxiety Di | 1978 |
Pharmacologic approach to sleep panic attacks.
Topics: Adult; Anxiety Disorders; Fear; Female; Humans; Imipramine; Lithium; Lithium Carbonate; Lorazepam; P | 1990 |
Lorazepam and sleep quality.
Topics: Adult; Humans; Lorazepam; Sleep; Sleep Wake Disorders | 1990 |
Tranquilizers and sedative/hypnotics: appropriate use in the elderly.
Topics: Aged; Alprazolam; Anti-Anxiety Agents; Anxiety; Benzodiazepines; Half-Life; Humans; Hypnotics and Se | 1986 |