Page last updated: 2024-10-30

lorazepam and Liver Cirrhosis

lorazepam has been researched along with Liver Cirrhosis in 4 studies

Lorazepam: A benzodiazepine used as an anti-anxiety agent with few side effects. It also has hypnotic, anticonvulsant, and considerable sedative properties and has been proposed as a preanesthetic agent.

Liver Cirrhosis: Liver disease in which the normal microcirculation, the gross vascular anatomy, and the hepatic architecture have been variably destroyed and altered with fibrous septa surrounding regenerated or regenerating parenchymal nodules.

Research Excerpts

ExcerptRelevanceReference
"Antipyrine elimination was significantly slower for cirrhotic patients."2.69Pharmacokinetics of minoxidil in patients with cirrhosis and healthy volunteers. ( Adams, MH; Ferry, JJ; Garnett, WR; Karnes, HT; Poynor, WJ; Ryan, KK; Sarkar, MA, 1998)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19902 (50.00)18.7374
1990's1 (25.00)18.2507
2000's0 (0.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lavoisier, J1
Boulle-Geronimi, C1
Mégarbane, B1
Adams, MH1
Poynor, WJ1
Garnett, WR1
Karnes, HT1
Ferry, JJ1
Ryan, KK1
Sarkar, MA1
Hoyumpa, AM1
Schenker, S1

Trials

1 trial available for lorazepam and Liver Cirrhosis

ArticleYear
Pharmacokinetics of minoxidil in patients with cirrhosis and healthy volunteers.
    Biopharmaceutics & drug disposition, 1998, Volume: 19, Issue:8

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Antipyrine; Area Under Curve; Biotransformation; Col

1998

Other Studies

3 other studies available for lorazepam and Liver Cirrhosis

ArticleYear
Fatality associated with propylene glycol poisoning in a cirrhotic patient.
    Clinical toxicology (Philadelphia, Pa.), 2016, Volume: 54, Issue:5

    Topics: Alanine Transaminase; Epinephrine; Fatal Outcome; Fomepizole; Humans; Liver Cirrhosis; Lorazepam; Ma

2016
Disposition and elimination of minor tranquilizers in the aged and in patients with liver disease.
    Southern medical journal, 1978, Volume: 71 Suppl 2

    Topics: Aged; Aging; Anti-Anxiety Agents; Chlordiazepoxide; Diazepam; Hepatitis; Humans; Liver Cirrhosis; Li

1978
Effects of liver disease and of aging on the disposition and elimination of sedatives.
    Transactions of the American Clinical and Climatological Association, 1978, Volume: 89

    Topics: Aging; Anti-Anxiety Agents; Chlordiazepoxide; Chlorpromazine; Diazepam; Half-Life; Hepatitis, Viral,

1978