lorazepam has been researched along with Kidney Failure, Chronic in 6 studies
Lorazepam: A benzodiazepine used as an anti-anxiety agent with few side effects. It also has hypnotic, anticonvulsant, and considerable sedative properties and has been proposed as a preanesthetic agent.
Kidney Failure, Chronic: The end-stage of CHRONIC RENAL INSUFFICIENCY. It is characterized by the severe irreversible kidney damage (as measured by the level of PROTEINURIA) and the reduction in GLOMERULAR FILTRATION RATE to less than 15 ml per min (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002). These patients generally require HEMODIALYSIS or KIDNEY TRANSPLANTATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Blood levels decline thereafter, with an elimination half-life of about 12 hrs." | 1.26 | Clinical pharmacokinetics of lorazepam: a review. ( Greenblatt, DJ; Kyriakopoulos, AA; Shader, RI, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yan, MT | 1 |
| Chau, T | 1 |
| Cheng, CJ | 1 |
| Lin, SH | 1 |
| Fung, EC | 1 |
| Crook, MA | 1 |
| Verbeeck, R | 1 |
| Tjandramaga, TB | 2 |
| Verberckmoes, R | 2 |
| De Schepper, PJ | 2 |
| Verbeeck, RK | 1 |
| Cawley, MJ | 1 |
| Kyriakopoulos, AA | 1 |
| Greenblatt, DJ | 1 |
| Shader, RI | 1 |
1 trial available for lorazepam and Kidney Failure, Chronic
| Article | Year |
|---|---|
Biotransformation and excretion of lorazepam in patients with chronic renal failure.
Topics: Adult; Anti-Anxiety Agents; Biotransformation; Humans; Kidney Failure, Chronic; Lorazepam; Male; Ren | 1976 |
5 other studies available for lorazepam and Kidney Failure, Chronic
| Article | Year |
|---|---|
Hunting down a double gap metabolic acidosis.
Topics: Acidosis; Aged; Alcoholism; Fatal Outcome; Female; Humans; Kidney Failure, Chronic; Lorazepam; Pneum | 2010 |
Closing in on the gaps.
Topics: Acidosis; Aged; Alcoholism; Female; Humans; Kidney Failure, Chronic; Lorazepam; Pneumonia, Ventilato | 2010 |
Impaired elimination of lorazepam following subchronic administration in two patients with renal failure.
Topics: Adult; Anti-Anxiety Agents; Humans; Kidney Failure, Chronic; Lorazepam; Male; Middle Aged | 1981 |
Short-term lorazepam infusion and concern for propylene glycol toxicity: case report and review.
Topics: Adult; Cocaine-Related Disorders; Critical Care; Diabetic Ketoacidosis; Excipients; Female; Hemodyna | 2001 |
Clinical pharmacokinetics of lorazepam: a review.
Topics: Administration, Oral; Age Factors; Anti-Anxiety Agents; Chromatography, Gas; Dose-Response Relations | 1978 |