lorazepam has been researched along with Hematologic Neoplasms in 3 studies
Lorazepam: A benzodiazepine used as an anti-anxiety agent with few side effects. It also has hypnotic, anticonvulsant, and considerable sedative properties and has been proposed as a preanesthetic agent.
Hematologic Neoplasms: Neoplasms located in the blood and blood-forming tissue (the bone marrow and lymphatic tissue). The commonest forms are the various types of LEUKEMIA, of LYMPHOMA, and of the progressive, life-threatening forms of the MYELODYSPLASTIC SYNDROMES.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The objective of this double blind parallel-group multicentre study was to compare the efficacy and safety of the combination ondansetron + methylprednisolone + lorazepam (O + M + L) in the prevention of emesis induced by chemotherapy with cyclophosphamide or adriamycin ." | 9.09 | [Improvement in the control of chemotherapy induced emesis with ondansetron, methylprednisolone and lorazepam combination in patients treated by a moderate emetic treatment and uncontrolled by a previous antiemetic combination]. ( Bonneterre, J; Harousseau, JL; Hedouin, M; Ouvry, J; Zittoun, R, 2000) |
| "The objective of this double blind parallel-group multicentre study was to compare the efficacy and safety of the combination ondansetron + methylprednisolone + lorazepam (O + M + L) in the prevention of emesis induced by chemotherapy with cyclophosphamide or adriamycin ." | 5.09 | [Improvement in the control of chemotherapy induced emesis with ondansetron, methylprednisolone and lorazepam combination in patients treated by a moderate emetic treatment and uncontrolled by a previous antiemetic combination]. ( Bonneterre, J; Harousseau, JL; Hedouin, M; Ouvry, J; Zittoun, R, 2000) |
| "Seizure is a recognized complication of high-dose busulfan (BU) therapy and phenytoin (DPH) is widely used as prophylaxis." | 2.70 | Lorazepam for seizure prophylaxis during high-dose busulfan administration. ( Chan, KW; Choroszy, M; Koontz, S; Mullen, CA; Slopis, J; Tran, H; Worth, LL, 2002) |
| " We evaluated the possibility of a pharmacokinetic (PK) drug-drug interaction between the antiemetic agents and high-dose cyclophosphamide, cisplatin and BCNU (CPA/cDDP/BCNU)." | 2.69 | Modification of the pharmacokinetics of high-dose cyclophosphamide and cisplatin by antiemetics. ( Bearman, SI; Cagnoni, PJ; Day, TC; Jones, RB; Matthes, S; Shpall, EJ, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cagnoni, PJ | 1 |
| Matthes, S | 1 |
| Day, TC | 1 |
| Bearman, SI | 1 |
| Shpall, EJ | 1 |
| Jones, RB | 1 |
| Harousseau, JL | 1 |
| Zittoun, R | 1 |
| Bonneterre, J | 1 |
| Hedouin, M | 1 |
| Ouvry, J | 1 |
| Chan, KW | 1 |
| Mullen, CA | 1 |
| Worth, LL | 1 |
| Choroszy, M | 1 |
| Koontz, S | 1 |
| Tran, H | 1 |
| Slopis, J | 1 |
3 trials available for lorazepam and Hematologic Neoplasms
| Article | Year |
|---|---|
Modification of the pharmacokinetics of high-dose cyclophosphamide and cisplatin by antiemetics.
Topics: Adult; Antiemetics; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Carmustine; Cisplatin; | 1999 |
[Improvement in the control of chemotherapy induced emesis with ondansetron, methylprednisolone and lorazepam combination in patients treated by a moderate emetic treatment and uncontrolled by a previous antiemetic combination].
Topics: Adult; Antiemetics; Breast Neoplasms; Double-Blind Method; Drug Therapy, Combination; Female; Hemato | 2000 |
Lorazepam for seizure prophylaxis during high-dose busulfan administration.
Topics: Adolescent; Adult; Anticonvulsants; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemo | 2002 |