lorazepam has been researched along with Epilepsy, Temporal Lobe in 11 studies
Lorazepam: A benzodiazepine used as an anti-anxiety agent with few side effects. It also has hypnotic, anticonvulsant, and considerable sedative properties and has been proposed as a preanesthetic agent.
Epilepsy, Temporal Lobe: A localization-related (focal) form of epilepsy characterized by recurrent seizures that arise from foci within the TEMPORAL LOBE, most commonly from its mesial aspect. A wide variety of psychic phenomena may be associated, including illusions, hallucinations, dyscognitive states, and affective experiences. The majority of complex partial seizures (see EPILEPSY, COMPLEX PARTIAL) originate from the temporal lobes. Temporal lobe seizures may be classified by etiology as cryptogenic, familial, or symptomatic. (From Adams et al., Principles of Neurology, 6th ed, p321).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Lorazepam appears to be a useful adjunct in refractory partial complex seizure therapy." | 2.65 | Lorazepam: a controlled trial in patients with intractable partial complex seizures. ( Crawford, IL; Homan, RW; Walker, JE, 1984) |
| "Kainic acid (KA) is a potent glutamate analog that is used to induce neurodegeneration and model temporal lobe epilepsy (TLE) in rodents." | 1.46 | A novel animal model of acquired human temporal lobe epilepsy based on the simultaneous administration of kainic acid and lorazepam. ( Bauer, S; Costard, L; Kienzler-Norwood, F; Müller, P; Neubert, V; Norwood, BA; Rosenow, F; Sadangi, C, 2017) |
| "With lorazepam there was a significant reduction in seizures, especially in those with focal and partial complex attacks." | 1.27 | Stress and epilepsy: the value of a benzodiazepine--lorazepam. ( Moffett, A; Scott, DF, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (36.36) | 18.7374 |
| 1990's | 2 (18.18) | 18.2507 |
| 2000's | 3 (27.27) | 29.6817 |
| 2010's | 2 (18.18) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kienzler-Norwood, F | 1 |
| Costard, L | 1 |
| Sadangi, C | 1 |
| Müller, P | 1 |
| Neubert, V | 1 |
| Bauer, S | 1 |
| Rosenow, F | 1 |
| Norwood, BA | 1 |
| Malur, C | 1 |
| Clark, A | 1 |
| Ricci, GB | 1 |
| De Carli, D | 1 |
| Colonnese, C | 1 |
| Di Gennaro, G | 1 |
| Quarato, PP | 1 |
| Cantore, G | 1 |
| Esposito, V | 1 |
| Garreffa, G | 1 |
| Maraviglia, B | 1 |
| Hug, BL | 1 |
| Walker, JE | 1 |
| Homan, RW | 1 |
| Crawford, IL | 1 |
| Moffett, A | 1 |
| Scott, DF | 1 |
| Jensen, FE | 1 |
| Wang, C | 1 |
| Brouns, R | 1 |
| Van Paesschen, W | 1 |
| Menza, MA | 1 |
| Lacey, DJ | 1 |
| Singer, WD | 1 |
| Horwitz, SJ | 1 |
| Gilmore, H | 1 |
| van Sweden, B | 1 |
| Hoste, S | 1 |
1 review available for lorazepam and Epilepsy, Temporal Lobe
| Article | Year |
|---|---|
Hypoxia-induced hyperexcitability in vivo and in vitro in the immature hippocampus.
Topics: Age Factors; Animals; Disease Models, Animal; Dizocilpine Maleate; Electroencephalography; Electroph | 1996 |
1 trial available for lorazepam and Epilepsy, Temporal Lobe
| Article | Year |
|---|---|
Lorazepam: a controlled trial in patients with intractable partial complex seizures.
Topics: Adult; Clinical Trials as Topic; Double-Blind Method; Epilepsy, Temporal Lobe; Humans; Lorazepam; Mi | 1984 |
9 other studies available for lorazepam and Epilepsy, Temporal Lobe
| Article | Year |
|---|---|
A novel animal model of acquired human temporal lobe epilepsy based on the simultaneous administration of kainic acid and lorazepam.
Topics: Animals; Anticonvulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Electroencephalo | 2017 |
Catatonia after right temporal lobe resection.
Topics: Adult; Anticonvulsants; Catatonia; Epilepsy, Temporal Lobe; Humans; Levetiracetam; Lorazepam; Male; | 2010 |
Hemodynamic response (BOLD/fMRI) in focal epilepsy with reference to benzodiazepine effect.
Topics: Adult; Anticonvulsants; Brain; Diazepam; Echo-Planar Imaging; Electroencephalography; Epilepsies, Pa | 2004 |
[Somnolence of unknown origin--illness or drug problem?].
Topics: Anticonvulsants; Carbamazepine; Diagnosis, Differential; Disorders of Excessive Somnolence; Drug Int | 2006 |
Stress and epilepsy: the value of a benzodiazepine--lorazepam.
Topics: Adult; Anticonvulsants; Drug Therapy, Combination; Electroencephalography; Epilepsies, Partial; Epil | 1984 |
Recurrent complex partial status epilepticus associated with tiagabine rechallenge.
Topics: Acetates; Adult; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Dose-Response | 2002 |
Lorazepam and catatonia.
Topics: Brain; Catatonia; Electroencephalography; Epilepsy, Temporal Lobe; Humans; Lorazepam | 1991 |
Lorazepam therapy of status epilepticus in children and adolescents.
Topics: Adolescent; Child; Child, Preschool; Drug Evaluation; Epilepsies, Partial; Epilepsy, Absence; Epilep | 1986 |
Are complex partial seizures an uncommon withdrawal sign in the elderly?
Topics: Aged; Aged, 80 and over; Electroencephalography; Epilepsy, Temporal Lobe; Ethanol; Evoked Potentials | 1987 |