lorazepam has been researched along with Depressive Disorder, Major in 26 studies
Lorazepam: A benzodiazepine used as an anti-anxiety agent with few side effects. It also has hypnotic, anticonvulsant, and considerable sedative properties and has been proposed as a preanesthetic agent.
Depressive Disorder, Major: Disorder in which five (or more) of the following symptoms have been present during the same 2-week period and represent a change from previous functioning; at least one of the symptoms is either (1) depressed mood or (2) loss of interest or pleasure. Symptoms include: depressed mood most of the day, nearly every daily; markedly diminished interest or pleasure in activities most of the day, nearly every day; significant weight loss when not dieting or weight gain; Insomnia or hypersomnia nearly every day; psychomotor agitation or retardation nearly every day; fatigue or loss of energy nearly every day; feelings of worthlessness or excessive or inappropriate guilt; diminished ability to think or concentrate, or indecisiveness, nearly every day; or recurrent thoughts of death, recurrent suicidal ideation without a specific plan, or a suicide attempt. (DSM-5)
| Excerpt | Relevance | Reference |
|---|---|---|
| "A young male with schizophrenia, dependence syndrome (multiple drug use) and a severe depressive episode develops a serotonin syndrome with Sertraline and Ziprasidone." | 7.85 | [Psychosis, Intoxication or Serotonin Syndrome? - A 20-Year Old Male with Ziprasidone und Sertraline]. ( Grabe, HJ; Janowitz, D; Schomerus, G; Speerforck, S, 2017) |
| "From a retrospective cohort of clinically depressed patients that were treated with rTMS, we compared 176 patients not taking any BZD with 73 patients taking lorazepam with respect to changes in the Hamilton Depression Rating Scale (HRDS)." | 4.02 | Concomitant lorazepam use and antidepressive efficacy of repetitive transcranial magnetic stimulation in a naturalistic setting. ( Abdelnaim, M; Deppe, M; Hebel, T; Kreuzer, PM; Langguth, B; Poeppl, TB; Schecklmann, M, 2021) |
| "A young male with schizophrenia, dependence syndrome (multiple drug use) and a severe depressive episode develops a serotonin syndrome with Sertraline and Ziprasidone." | 3.85 | [Psychosis, Intoxication or Serotonin Syndrome? - A 20-Year Old Male with Ziprasidone und Sertraline]. ( Grabe, HJ; Janowitz, D; Schomerus, G; Speerforck, S, 2017) |
| "Patients with catatonia who had more than one episode of catatonia and were treated with the lorazepam-diazepam protocol were identified." | 3.83 | Relapses and recurrences of catatonia: 30-case analysis and literature review. ( Huang, TL; Hung, YY; Lin, CC; Tsai, MC, 2016) |
| " Here, we report a case of the use of the benzodiazepine antagonist flumazenil before ECT to facilitate the simultaneous use of lorazepam and ECT for the treatment of co-occurring catatonia and obsessive-compulsive disorder." | 3.78 | Successful treatment of co-occurring catatonia and obsessive-compulsive disorder with concurrent electroconvulsive therapy and benzodiazepine administration. ( Furst, BA; Kwon, GE; Makhinson, M; Shuff, MK, 2012) |
| "Anxiety is common among persons with alcohol use disorder during early abstinence from alcohol." | 2.82 | Coadministration of disulfiram and lorazepam in the treatment of alcohol dependence and co-occurring anxiety disorder: an open-label pilot study. ( Bhatt, S; Bogenschutz, MP; Bohan, J; Foster, B; Romo, P; Tonigan, JS; Wilcox, CE, 2016) |
| "Aripiprazole was dosed flexibly up to a maximum of 30 mg daily, based on tolerability and efficacy." | 2.73 | A prospective, open-label study of Aripiprazole mono- and adjunctive treatment in acute bipolar depression. ( Chriki, LS; Dunn, RT; Filkowski, MM; Ghaemi, SN; Stan, VA, 2008) |
| "Tardive seizures are typically associated with electroencephalographic evidence of ictal activity and motor manifestations of the tonic-clonic activity." | 1.40 | A case of atypical tardive seizure activity during an initial ECT titration series. ( Karim, Y; McCormick, LM; Thisayakorn, P; Yamada, T, 2014) |
| "Studies in major depressive disorder have demonstrated that suprathreshold, nondominant (right) hemisphere, unilateral electrode placement ECT has fewer adverse effects, especially cognitive adverse effects, than bitemporal ECT." | 1.40 | Successful use of right unilateral ECT for catatonia: a case series. ( Conway, C; Cristancho, P; Jewkes, D; Mon, T, 2014) |
| "Catatonia is a well-described neuropsychiatric syndrome that has been the subject of several texts." | 1.37 | Cases of catatonia on an academic electroconvulsive therapy service: lessons to learn. ( Aloysi, AS; Kellner, CH; Popeo, DM, 2011) |
| "Drug-induced delirium is a common matter in the elderly and anticholinergics, together with a number of different drugs, may significantly contribute to the delirium onset, especially in demented people." | 1.34 | Anticholinergic drug-induced delirium in an elderly Alzheimer's dementia patient. ( Cotroneo, A; De Fazio, P; De Fazio, S; De Sarro, G; Gallelli, L; Gareri, P; Lacava, R, 2007) |
| "Any prolonged cognitive alterations or confusional states may have additional causes and require extensive diagnostic effort." | 1.33 | Prolonged confusional state following electroconvulsive therapy--diagnostic clues from serial electroencephalography. ( Ehrentraut, S; Hegerl, U; Henkel, V; Möller, HJ; Mulert, C; Pogarell, O; Rüther, T, 2005) |
| "Both pseudoseizures and hysterical stridor are associated commonly with sexual abuse, eating disorders, depression, substance abuse, anxiety disorders, and personality disorders." | 1.32 | Pseudoseizures and hysterical stridor. ( Kaufman, KR; Mohebati, A; Sotolongo, A, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (7.69) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 9 (34.62) | 29.6817 |
| 2010's | 13 (50.00) | 24.3611 |
| 2020's | 2 (7.69) | 2.80 |
| Authors | Studies |
|---|---|
| Nikjoo, A | 1 |
| Wright, C | 1 |
| Kheriaty, A | 1 |
| Deppe, M | 1 |
| Abdelnaim, M | 1 |
| Hebel, T | 1 |
| Kreuzer, PM | 1 |
| Poeppl, TB | 1 |
| Langguth, B | 1 |
| Schecklmann, M | 1 |
| Parks, KA | 1 |
| Parks, CG | 1 |
| Onwuameze, OE | 1 |
| Shrestha, S | 1 |
| Speerforck, S | 1 |
| Janowitz, D | 1 |
| Schomerus, G | 1 |
| Grabe, HJ | 1 |
| Ratzlaff, M | 1 |
| Harrington, M | 1 |
| Thisayakorn, P | 1 |
| Karim, Y | 1 |
| Yamada, T | 1 |
| McCormick, LM | 1 |
| Pai, MS | 1 |
| Yang, SN | 1 |
| Lin, JC | 1 |
| Shiah, IS | 1 |
| Cristancho, P | 1 |
| Jewkes, D | 1 |
| Mon, T | 1 |
| Conway, C | 1 |
| del Río-Casanova, L | 1 |
| Portela, B | 1 |
| Díaz-Llenderrozas, F | 1 |
| Lin, CC | 1 |
| Hung, YY | 1 |
| Tsai, MC | 1 |
| Huang, TL | 2 |
| Bogenschutz, MP | 1 |
| Bhatt, S | 1 |
| Bohan, J | 1 |
| Foster, B | 1 |
| Romo, P | 1 |
| Wilcox, CE | 1 |
| Tonigan, JS | 1 |
| Bonnet, U | 1 |
| Ringel, P | 1 |
| Park, YM | 1 |
| Lee, HJ | 1 |
| Kang, SG | 1 |
| Choo, CS | 1 |
| Cho, JH | 1 |
| Aloysi, AS | 1 |
| Popeo, DM | 1 |
| Kellner, CH | 2 |
| Miljevic, CD | 1 |
| Kecojevic-Miljevic, S | 1 |
| Crnobaric, C | 1 |
| Lecic-Tosevski, D | 1 |
| Makhinson, M | 1 |
| Furst, BA | 1 |
| Shuff, MK | 1 |
| Kwon, GE | 1 |
| Eichhorn, M | 1 |
| Eich, P | 1 |
| Lai, JY | 1 |
| Kaufman, KR | 1 |
| Mohebati, A | 1 |
| Sotolongo, A | 1 |
| Pogarell, O | 1 |
| Ehrentraut, S | 1 |
| Rüther, T | 1 |
| Mulert, C | 1 |
| Hegerl, U | 1 |
| Möller, HJ | 1 |
| Henkel, V | 1 |
| Gareri, P | 1 |
| De Fazio, P | 1 |
| Cotroneo, A | 1 |
| Lacava, R | 1 |
| Gallelli, L | 1 |
| De Fazio, S | 1 |
| De Sarro, G | 1 |
| Rasmussen, KG | 1 |
| Mueller, M | 1 |
| Knapp, RG | 1 |
| Husain, MM | 1 |
| Rummans, TA | 1 |
| Sampson, SM | 1 |
| O'Connor, MK | 1 |
| Petrides, G | 1 |
| Fink, M | 1 |
| Dunn, RT | 1 |
| Stan, VA | 1 |
| Chriki, LS | 1 |
| Filkowski, MM | 1 |
| Ghaemi, SN | 1 |
| Stewart, RB | 1 |
| Salem, RB | 1 |
| Springer, PK | 1 |
| Kopp, M | 1 |
| Holzner, B | 1 |
| Brugger, A | 1 |
| Nachbaur, D | 1 |
| Singer, L | 1 |
| Finance, MF | 1 |
| Ruh, MD | 1 |
1 review available for lorazepam and Depressive Disorder, Major
| Article | Year |
|---|---|
[Venlafaxine-induced delirium mediated by high doses].
Topics: Aged; Antidepressive Agents; Comorbidity; Confusion; Delirium; Depressive Disorder, Major; Dopamine; | 2015 |
3 trials available for lorazepam and Depressive Disorder, Major
| Article | Year |
|---|---|
Coadministration of disulfiram and lorazepam in the treatment of alcohol dependence and co-occurring anxiety disorder: an open-label pilot study.
Topics: Adult; Alcoholism; Anxiety Disorders; Craving; Depressive Disorder, Major; Disulfiram; Drug Therapy, | 2016 |
Antidepressant medication treatment failure does not predict lower remission with ECT for major depressive disorder: a report from the consortium for research in electroconvulsive therapy.
Topics: Adult; Antidepressive Agents; Depressive Disorder, Major; Diagnostic and Statistical Manual of Menta | 2007 |
A prospective, open-label study of Aripiprazole mono- and adjunctive treatment in acute bipolar depression.
Topics: Acute Disease; Adolescent; Adult; Akathisia, Drug-Induced; Ambulatory Care; Antidepressive Agents; A | 2008 |
22 other studies available for lorazepam and Depressive Disorder, Major
| Article | Year |
|---|---|
A Case Report of Scrupulosity Presenting as Catatonia in a Patient With Both OCD and OCPD.
Topics: Catatonia; Depressive Disorder, Major; Female; Humans; Lorazepam; Obsessive-Compulsive Disorder | 2022 |
Concomitant lorazepam use and antidepressive efficacy of repetitive transcranial magnetic stimulation in a naturalistic setting.
Topics: Depression; Depressive Disorder, Major; Female; Humans; Lorazepam; Male; Middle Aged; Retrospective | 2021 |
Psychiatric Complications of Primary Hyperparathyroidism and Mild Hypercalcemia.
Topics: Aged, 80 and over; Antipsychotic Agents; Depressive Disorder, Major; Female; GABA Modulators; Humans | 2017 |
[Psychosis, Intoxication or Serotonin Syndrome? - A 20-Year Old Male with Ziprasidone und Sertraline].
Topics: Depressive Disorder, Major; Dose-Response Relationship, Drug; Drug Therapy, Combination; Humans; Lor | 2017 |
A dramatic case of a woman discovered after 7 months of untreated catatonia.
Topics: Catatonia; Depressive Disorder, Major; Electroconvulsive Therapy; Female; Humans; Hypnotics and Seda | 2018 |
A case of atypical tardive seizure activity during an initial ECT titration series.
Topics: Adult; Anticonvulsants; Brain; Depressive Disorder, Major; Electroconvulsive Therapy; Electroencepha | 2014 |
Antiretroviral agent entecavir exacerbates major depression.
Topics: Anti-Anxiety Agents; Antidepressive Agents; Antiviral Agents; Citalopram; Depressive Disorder, Major | 2013 |
Successful use of right unilateral ECT for catatonia: a case series.
Topics: Adolescent; Adult; Aged, 80 and over; Antipsychotic Agents; Bipolar Disorder; Catatonia; Depressive | 2014 |
Relapses and recurrences of catatonia: 30-case analysis and literature review.
Topics: Adolescent; Adult; Antipsychotic Agents; Bipolar Disorder; Catatonia; Clozapine; Depressive Disorder | 2016 |
Black Hairy Tongue Associated With Lorazepam Treatment of a Male Smoker With Major Depression.
Topics: Anti-Anxiety Agents; Anxiety; Depressive Disorder, Major; Humans; Lorazepam; Male; Middle Aged; Tong | 2017 |
Tardive dyskinesia associated with long-term administration of escitalopram and itopride in major depressive disorder.
Topics: Aged; Anti-Anxiety Agents; Antidepressive Agents, Second-Generation; Benzamides; Benzyl Compounds; B | 2009 |
Cases of catatonia on an academic electroconvulsive therapy service: lessons to learn.
Topics: Aged; Aged, 80 and over; Anxiety Disorders; Catatonia; Depressive Disorder; Depressive Disorder, Maj | 2011 |
A rare case of male hysteria - hemiparesis successfully treated with amitriptyline.
Topics: Adult; Amitriptyline; Anti-Anxiety Agents; Antidepressive Agents, Second-Generation; Antidepressive | 2011 |
Successful treatment of co-occurring catatonia and obsessive-compulsive disorder with concurrent electroconvulsive therapy and benzodiazepine administration.
Topics: Adult; Benzodiazepines; Catatonia; Combined Modality Therapy; Depressive Disorder, Major; Electrocon | 2012 |
[Dextromethorphane intoxication under co-medication with cytochrome P450-inhibitor fluoxetin: prolonged and accentuated signs of intoxication].
Topics: Adult; Antitussive Agents; Cytochrome P-450 Enzyme Inhibitors; Depressive Disorder, Major; Dextromet | 2002 |
Catatonic features noted in patients with post-partum mental illness.
Topics: Adult; Benzodiazepines; Catatonia; Cross-Sectional Studies; Depression, Postpartum; Depressive Disor | 2004 |
Pseudoseizures and hysterical stridor.
Topics: Academic Medical Centers; Adult; Anti-Anxiety Agents; Anticonvulsants; Antidepressive Agents, Second | 2004 |
Prolonged confusional state following electroconvulsive therapy--diagnostic clues from serial electroencephalography.
Topics: Amnesia; Anticonvulsants; Cognition; Confusion; Depressive Disorder, Major; Electroconvulsive Therap | 2005 |
Anticholinergic drug-induced delirium in an elderly Alzheimer's dementia patient.
Topics: Acute Disease; Aged, 80 and over; Alzheimer Disease; Amitriptyline; Antipsychotic Agents; Cholinergi | 2007 |
A case report of lorazepam withdrawal.
Topics: Anti-Anxiety Agents; Depressive Disorder, Major; Dose-Response Relationship, Drug; Female; Humans; L | 1980 |
Successful management of claustrophobia and depression during allogeneic SCT.
Topics: Adult; Anti-Anxiety Agents; Anxiety; Cognitive Behavioral Therapy; Combined Modality Therapy; Cranio | 2001 |
[Pulmonary embolisms occurring in 1 month in 3 aged women with manic-depressive psychoses. Discussion. Etiopathogenic role or psychiatric treatment].
Topics: Aged; Antidepressive Agents; Bipolar Disorder; Chlorpromazine; Clomipramine; Depressive Disorder, Ma | 1975 |