Page last updated: 2024-10-30

lorazepam and Dementia Praecox

lorazepam has been researched along with Dementia Praecox in 54 studies

Lorazepam: A benzodiazepine used as an anti-anxiety agent with few side effects. It also has hypnotic, anticonvulsant, and considerable sedative properties and has been proposed as a preanesthetic agent.

Research Excerpts

ExcerptRelevanceReference
" Acutely agitated patients with schizophrenia or schizoaffective disorder (n = 67) were randomized to receive 10 mg IM olanzapine (n = 37) or 5 mg IM haloperidol plus 2 mg IM lorazepam (n = 30)."9.20Intramuscular olanzapine versus intramuscular haloperidol plus lorazepam for the treatment of acute schizophrenia with agitation: An open-label, randomized controlled trial. ( Chen, HH; Chen, YH; Hsieh, MH; Huang, CL; Huang, GH; Hwang, TJ; Hwu, HG, 2015)
"The lorazepam-diazepam protocol can rapidly relieve retarded catatonia in schizophrenia."9.17Lorazepam-diazepam protocol for catatonia in schizophrenia: a 21-case analysis. ( Huang, TL; Lin, CC, 2013)
"Cognitive impairment causes morbidity in schizophrenia and could be due to abnormalities of cortical interneurons using the inhibitory neurotransmitter gamma-aminobutyric acid (GABA)."9.12Effects of gamma-aminobutyric acid-modulating drugs on working memory and brain function in patients with schizophrenia. ( Bullmore, E; Fletcher, P; Kamath, S; McKenna, P; Menzies, L; Ooi, C; Stephenson, C; Suckling, J, 2007)
"We conducted a prospective double-blind study of accelerated dose titration of olanzapine in the treatment of newly admitted acutely agitated patients with schizophrenia."9.11Efficacy of accelerated dose titration of olanzapine with adjunctive lorazepam to treat acute agitation in schizophrenia. ( Ahl, J; Kinon, BJ; McMullen, E; Rotelli, MD, 2004)
"The objective of this study was to estimate the effects of intramuscular haloperidol and lorazepam on the QT interval in volunteers with schizophrenia."9.11Intramuscular haloperidol or lorazepam and QT intervals in schizophrenia. ( Burke, M; Flockhart, D; Gorski, JC; Greenblatt, DJ; Harvey, AT; Preskorn, SH; Werder, S, 2004)
" The authors compared the efficacy and tolerability of ziprasidone and olanzapine in the treatment of acutely ill inpatients with schizophrenia or schizoaffective disorder."9.11Randomized, controlled, double-blind multicenter comparison of the efficacy and tolerability of ziprasidone and olanzapine in acutely ill inpatients with schizophrenia or schizoaffective disorder. ( Glick, ID; Romano, SJ; Simpson, GM; Siu, CO; Weiden, PJ, 2004)
"Lorazepam was also given as needed (total dose, < or =4 mg/d) but not in place of a study drug dose increase."6.73Olanzapine versus aripiprazole for the treatment of agitation in acutely ill patients with schizophrenia. ( Chen, L; Kinon, BJ; Kollack-Walker, S; Sniadecki, J; Stauffer, VL, 2008)
" Acutely agitated patients with schizophrenia or schizoaffective disorder (n = 67) were randomized to receive 10 mg IM olanzapine (n = 37) or 5 mg IM haloperidol plus 2 mg IM lorazepam (n = 30)."5.20Intramuscular olanzapine versus intramuscular haloperidol plus lorazepam for the treatment of acute schizophrenia with agitation: An open-label, randomized controlled trial. ( Chen, HH; Chen, YH; Hsieh, MH; Huang, CL; Huang, GH; Hwang, TJ; Hwu, HG, 2015)
"The lorazepam-diazepam protocol can rapidly relieve retarded catatonia in schizophrenia."5.17Lorazepam-diazepam protocol for catatonia in schizophrenia: a 21-case analysis. ( Huang, TL; Lin, CC, 2013)
"Cognitive impairment causes morbidity in schizophrenia and could be due to abnormalities of cortical interneurons using the inhibitory neurotransmitter gamma-aminobutyric acid (GABA)."5.12Effects of gamma-aminobutyric acid-modulating drugs on working memory and brain function in patients with schizophrenia. ( Bullmore, E; Fletcher, P; Kamath, S; McKenna, P; Menzies, L; Ooi, C; Stephenson, C; Suckling, J, 2007)
"We conducted a prospective double-blind study of accelerated dose titration of olanzapine in the treatment of newly admitted acutely agitated patients with schizophrenia."5.11Efficacy of accelerated dose titration of olanzapine with adjunctive lorazepam to treat acute agitation in schizophrenia. ( Ahl, J; Kinon, BJ; McMullen, E; Rotelli, MD, 2004)
"The objective of this study was to estimate the effects of intramuscular haloperidol and lorazepam on the QT interval in volunteers with schizophrenia."5.11Intramuscular haloperidol or lorazepam and QT intervals in schizophrenia. ( Burke, M; Flockhart, D; Gorski, JC; Greenblatt, DJ; Harvey, AT; Preskorn, SH; Werder, S, 2004)
" The authors compared the efficacy and tolerability of ziprasidone and olanzapine in the treatment of acutely ill inpatients with schizophrenia or schizoaffective disorder."5.11Randomized, controlled, double-blind multicenter comparison of the efficacy and tolerability of ziprasidone and olanzapine in acutely ill inpatients with schizophrenia or schizoaffective disorder. ( Glick, ID; Romano, SJ; Simpson, GM; Siu, CO; Weiden, PJ, 2004)
" In 3 double-blind studies, acutely agitated patients with schizophrenia (N = 311), bipolar mania (N = 201), or dementia (N = 206) were treated with intramuscular (1-3 injections/24 hrs) olanzapine (2."5.10Calming versus sedative effects of intramuscular olanzapine in agitated patients. ( Alaka, K; Battaglia, J; Lindborg, SR; Meehan, K; Wright, P, 2003)
"Over 67 days, 1,461 patients were screened in the ED, 269 had bipolar I or schizophrenia, 194 of whom had a contraindication to inhaled loxapine leaving 75 eligible patients; preconsent was obtained in 43 patients."3.91Study Enrollment When "Preconsent" Is Utilized for a Randomized Clinical Trial of Two Treatments for Acute Agitation in the Emergency Department. ( Cole, JB; Driver, BE; Klein, LR; Mullinax, SZ; Nordstrom, KD; Wilson, MP, 2019)
"The involvement of the gamma-aminobutyric acid (GABA) system in schizophrenia is suggested by postmortem studies and the common use of GABA receptor-potentiating agents in treatment."3.81Abnormal GABAergic function and face processing in schizophrenia: A pharmacologic-fMRI study. ( Fang, Y; Phan, KL; Taylor, SF; Tso, IF; Welsh, RC, 2015)
"Analysis 1 found that nonsedated patients with bipolar I disorder and schizophrenia showed significant decreases in PEC scores following treatment with aripiprazole IM (p < 0."3.74Intramuscular aripiprazole in the control of agitation. ( Citrome, LL; Crandall, DT; Currier, GW; Manos, G; McQuade, R; Oren, D; Pikalov, AA; Zimbroff, DL, 2007)
" The concentration remained almost unaltered after 4 weeks of zuclopenthixol treatment in the schizophrenia group and following various neuroleptic, antidepressant, and anxiolytic medications in the nonschizophrenic patients despite a significant decrease of overt psychopathology assessed by the Brief Psychiatric Rating Scale."3.68Somatostatin in the cerebrospinal fluid of schizophrenic patients before and after neuroleptic drug treatment. ( Heikkilä, L, 1993)
"Lorazepam was also given as needed (total dose, < or =4 mg/d) but not in place of a study drug dose increase."2.73Olanzapine versus aripiprazole for the treatment of agitation in acutely ill patients with schizophrenia. ( Chen, L; Kinon, BJ; Kollack-Walker, S; Sniadecki, J; Stauffer, VL, 2008)
" Mean daily lorazepam dosage was 0."2.67Haloperidol and lorazepam combined: clinical effects and drug plasma levels in the treatment of acute schizophrenic psychosis. ( Gaertner, HJ; Mahal, A; Stevens, A; Stevens, I, 1992)
"Catatonia is a clinical syndrome characterized by psychomotor disruption, which often goes undiagnosed."1.62Refractory catatonia in old age: a case report. ( Amin, J; Bean, E; Findlay, C; Gee, C, 2021)
"We recommend being alert for catatonia in patients with or without a psychiatric disorder."1.36[Catatonia]. ( Blom, JD; Bruijn, DJ, 2010)

Research

Studies (54)

TimeframeStudies, this research(%)All Research%
pre-19904 (7.41)18.7374
1990's12 (22.22)18.2507
2000's16 (29.63)29.6817
2010's18 (33.33)24.3611
2020's4 (7.41)2.80

Authors

AuthorsStudies
Spiegel, DR1
Ayzman, A1
Reid, FE1
Ahuja, K1
Worfolk, J1
Ali, SA1
Moyett, A1
Argyelan, M1
Barber, AD1
Homan, P1
Rubio, JM1
Fales, C1
Gallego, JA1
Lencz, T1
Malhotra, AK1
Gouse, BM1
Spears, WE1
Nieves Archibald, A1
Montalvo, C1
Bean, E1
Findlay, C1
Gee, C1
Amin, J1
Kar, SK1
Srivastava, A1
Kathirvel, N1
Ghosh, AK1
Agrawal, AK1
Das, S1
Cevher Binici, N1
Topal, Z1
Demir Samurcu, N1
Cansız, MA1
Savcı, U1
Öztürk, Y1
Özyurt, G1
Tufan, AE1
Cole, JB1
Klein, LR1
Mullinax, SZ1
Nordstrom, KD1
Driver, BE1
Wilson, MP1
Lin, CC1
Huang, TL1
Taylor, SF2
Demeter, E1
Phan, KL2
Tso, IF2
Welsh, RC2
Guru, S1
Vanamoorthy, U1
Loganathan, S1
Varghese, M1
Rausch, F1
Mier, D1
Eifler, S1
Fenske, S1
Schirmbeck, F1
Englisch, S1
Schilling, C1
Meyer-Lindenberg, A2
Kirsch, P1
Zink, M1
Huang, CL1
Hwang, TJ1
Chen, YH1
Huang, GH1
Hsieh, MH1
Chen, HH1
Hwu, HG1
Fang, Y1
Villamil, EA1
Gonzalez, R1
Kinon, BJ2
Stauffer, VL1
Kollack-Walker, S1
Chen, L1
Sniadecki, J1
Dyer, C1
Hoyer, C1
Kranaster, L1
Leweke, FM1
Klosterkötter, J1
Koethe, D1
Zilles, D1
Hasan, A1
Gruber, O1
Degner, D1
Bruijn, DJ1
Blom, JD1
Coffey, MJ1
Wang, BZ1
Gupta, A1
Bastiampillai, T1
Sani, F1
Battaglia, J2
Lindborg, SR1
Alaka, K1
Meehan, K1
Wright, P1
Sielk, M1
Lange, N1
Ahl, J1
Rotelli, MD1
McMullen, E1
Lejeune, J1
Larmo, I1
Chrzanowski, W1
Witte, R1
Karavatos, A1
Schreiner, A1
Lex, A1
Medori, R2
Harvey, AT1
Flockhart, D1
Gorski, JC1
Greenblatt, DJ1
Burke, M1
Werder, S1
Preskorn, SH1
Härtter, S1
Connemann, B1
Schönfeldt-Lecuona, C1
Sachse, J1
Hiemke, C1
Simpson, GM1
Glick, ID1
Weiden, PJ1
Romano, SJ1
Siu, CO1
Chakraborty, N1
Johnston, T1
Carnahan, RM1
Perry, PJ1
Mendhekar, DN1
Jiloha, RC1
Menzies, L1
Ooi, C1
Kamath, S1
Suckling, J1
McKenna, P1
Fletcher, P1
Bullmore, E1
Stephenson, C1
Currier, GW1
Citrome, LL1
Zimbroff, DL2
Oren, D1
Manos, G1
McQuade, R1
Pikalov, AA1
Crandall, DT1
Emsley, R1
Koen, L1
Oosthuizen, PP1
Niehaus, DJ1
Rabinowitz, J1
Jaspert, A1
Ebert, D1
Bailine, SH1
Safferman, A1
Vital-Herne, J1
Bernstein, S1
Heikkilä, L1
Northoff, G1
Wenke, J1
Demisch, L1
Eckert, J1
Gille, B1
Pflug, B1
Donnelly, CL1
McEvoy, JP1
Wilson, WH1
Narasimhachari, N1
Lee, JW1
Schwartz, DL1
Kramer, MS1
Last, B1
Getson, A1
Reines, SA1
Lane, HY1
Su, KP1
Chang, WH1
Kanofsky, JD1
Sandyk, R1
Stevens, A1
Stevens, I1
Mahal, A1
Gaertner, HJ1
Gracia, RI1
Gutierrez, JM1
Faraone, SV1
Tsuang, MT1
Yassa, R1
Nastase, C1
Belzile, L1
Adler, L1
Angrist, B1
Peselow, E1
Corwin, J1
Rotrosen, J1
Chouinard, G1
Fraser, AA1
Ingram, IM1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
An Observational Study of Anti-Psychotic Medication for the Treatment of Agitation in the Emergency Department[NCT02877108]100 participants (Anticipated)Observational2016-04-30Recruiting
An Open-label, Randomized Trial of Intramuscular (IM) Olanzapine Versus Intramuscular Combination of Haloperidol and Lorazepam in the Treatment of Acute Agitation in Schizophrenia[NCT00797277]Phase 367 participants (Actual)Interventional2006-07-31Completed
Comparison of Oral Risperdal in Combination With Oral Lorazepam vs Standard Care Including Initial Conventional Neuroleptic IM Treatment, in Acute Schizophrenic Patients[NCT00249171]Phase 4226 participants (Actual)Interventional2001-06-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Change of the Agitation-Calmness Evaluation Scale (ACES) Score From Baseline to 120 Minutes After 1st Injection

Agitation was further assessed by the Agitation Calmness Evaluation Scale (ACES) (Copyright 1998, Eli Lilly and Company), a single-item scale developed by Eli Lilly and Company on which 1 indicates marked agitation; 2, moderate agitation; 3, mild agitation; 4, normal; 5, mild calmness; 6, moderate calmness; 7, marked calmness; 8, deep sleep; and 9, unable to be aroused. (NCT00797277)
Timeframe: from baseline to 120 minutes after first injection

Interventionunits on a scale (Mean)
1. IM Olanzapine2.14
2. IM Haloperidol Pus Lorazepam2.23

The Change of the Positive and Negative Symptom Scale Excited Component (PANSS-EC) Score From Baseline to 120 Minutes After First Injection

The primary efficacy measure was PANSS-EC, which was derived from the PANSS by its originators using a principal-components factor analysis, and includes the items of tension, uncooperativeness, hostility, poor impulse control and excitement.22 The score of each item ranges from 1 (normal) to 7 (most severe), with a total sum score ranging from 5 to 35. The changes in PANSS-EC from baseline to 2 hours after the first injection were compared. (NCT00797277)
Timeframe: from baseline to 120 minutes after first injection

Interventionunits on a scale (Mean)
1. IM Olanzapine-10.2
2. IM Haloperidol Plus Lorazepam-9.9

Reviews

2 reviews available for lorazepam and Dementia Praecox

ArticleYear
[Problems with the treatment of schizophrenics in the doctor's office].
    MMW Fortschritte der Medizin, 2003, May-26, Volume: 145 Suppl 2

    Topics: Acute Disease; Adult; Anti-Anxiety Agents; Antipsychotic Agents; Diazepam; Drug Therapy, Combination

2003
The treatment of acute agitation in schizophrenia.
    CNS spectrums, 2007, Volume: 12, Issue:8 Suppl 11

    Topics: Acute Disease; Antipsychotic Agents; Humans; Hypnotics and Sedatives; Lorazepam; Psychomotor Agitati

2007

Trials

18 trials available for lorazepam and Dementia Praecox

ArticleYear
Lorazepam-diazepam protocol for catatonia in schizophrenia: a 21-case analysis.
    Comprehensive psychiatry, 2013, Volume: 54, Issue:8

    Topics: Anti-Anxiety Agents; Catatonia; Clinical Protocols; Diazepam; Drug Therapy, Combination; Humans; Lor

2013
Abnormal GABAergic function and negative affect in schizophrenia.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2014, Volume: 39, Issue:4

    Topics: Adult; Cerebral Cortex; Cross-Over Studies; Female; GABA Modulators; gamma-Aminobutyric Acid; Humans

2014
Intramuscular olanzapine versus intramuscular haloperidol plus lorazepam for the treatment of acute schizophrenia with agitation: An open-label, randomized controlled trial.
    Journal of the Formosan Medical Association = Taiwan yi zhi, 2015, Volume: 114, Issue:5

    Topics: Adult; Antipsychotic Agents; Benzodiazepines; Drug Therapy, Combination; Female; Haloperidol; Humans

2015
Olanzapine versus aripiprazole for the treatment of agitation in acutely ill patients with schizophrenia.
    Journal of clinical psychopharmacology, 2008, Volume: 28, Issue:6

    Topics: Acute Disease; Administration, Oral; Adolescent; Adult; Aged; Antipsychotic Agents; Aripiprazole; Be

2008
Calming versus sedative effects of intramuscular olanzapine in agitated patients.
    The American journal of emergency medicine, 2003, Volume: 21, Issue:3

    Topics: Adult; Anti-Anxiety Agents; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Dementia; Doubl

2003
What can modern statistics offer imaging neuroscience?
    Statistical methods in medical research, 2003, Volume: 12, Issue:5

    Topics: Alzheimer Disease; Brain Mapping; GABA Modulators; Hippocampus; Humans; Lorazepam; Magnetic Resonanc

2003
Efficacy of accelerated dose titration of olanzapine with adjunctive lorazepam to treat acute agitation in schizophrenia.
    The American journal of emergency medicine, 2004, Volume: 22, Issue:3

    Topics: Acute Disease; Administration, Oral; Adult; Anti-Anxiety Agents; Antipsychotic Agents; Benzodiazepin

2004
Oral risperidone plus oral lorazepam versus standard care with intramuscular conventional neuroleptics in the initial phase of treating individuals with acute psychosis.
    International clinical psychopharmacology, 2004, Volume: 19, Issue:5

    Topics: Acute Disease; Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Aggression; Antipsy

2004
Intramuscular haloperidol or lorazepam and QT intervals in schizophrenia.
    Journal of clinical pharmacology, 2004, Volume: 44, Issue:10

    Topics: Adult; Confidence Intervals; Cross-Over Studies; Electrocardiography; Female; Haloperidol; Humans; I

2004
Randomized, controlled, double-blind multicenter comparison of the efficacy and tolerability of ziprasidone and olanzapine in acutely ill inpatients with schizophrenia or schizoaffective disorder.
    The American journal of psychiatry, 2004, Volume: 161, Issue:10

    Topics: Adolescent; Adult; Antipsychotic Agents; Benzodiazepines; Double-Blind Method; Drug Administration S

2004
Effects of gamma-aminobutyric acid-modulating drugs on working memory and brain function in patients with schizophrenia.
    Archives of general psychiatry, 2007, Volume: 64, Issue:2

    Topics: Adult; Brain; Cerebral Cortex; Cognition Disorders; Double-Blind Method; Flumazenil; GABA Modulators

2007
Long-acting injectable risperidone in the treatment of subjects with recent-onset psychosis: a preliminary study.
    Journal of clinical psychopharmacology, 2008, Volume: 28, Issue:2

    Topics: Adolescent; Adult; Antidepressive Agents; Blood Glucose; Body Mass Index; Cholesterol; Delayed-Actio

2008
Catatonia: short-term response to lorazepam and dopaminergic metabolism.
    Psychopharmacology, 1995, Volume: 122, Issue:2

    Topics: Acute Disease; Adult; Anti-Anxiety Agents; Anxiety; Catatonia; Depressive Disorder; Dopamine; Dyskin

1995
A study of the potential confounding effects of diet, caffeine, nicotine and lorazepam on the stability of plasma and urinary homovanillic acid levels in patients with schizophrenia.
    Biological psychiatry, 1996, Dec-15, Volume: 40, Issue:12

    Topics: Adult; Caffeine; Central Nervous System Stimulants; Diet; Drug Interactions; GABA Modulators; Homova

1996
The effects of a selective D4 dopamine receptor antagonist (L-745,870) in acutely psychotic inpatients with schizophrenia. D4 Dopamine Antagonist Group.
    Archives of general psychiatry, 1997, Volume: 54, Issue:6

    Topics: Acute Disease; Adult; Antipsychotic Agents; Chloral Hydrate; Dopamine Antagonists; Double-Blind Meth

1997
Haloperidol and lorazepam combined: clinical effects and drug plasma levels in the treatment of acute schizophrenic psychosis.
    Pharmacopsychiatry, 1992, Volume: 25, Issue:6

    Topics: Acute Disease; Adult; Drug Therapy, Combination; Female; Haloperidol; Humans; Lorazepam; Male; Middl

1992
Efficacy of propranolol in neuroleptic-induced akathesia.
    Journal of clinical psychopharmacology, 1985, Volume: 5, Issue:3

    Topics: Adult; Akathisia, Drug-Induced; Antipsychotic Agents; Chronic Disease; Female; Humans; Lorazepam; Ma

1985
The use of benzodiazepines in the treatment of manic-depressive illness.
    The Journal of clinical psychiatry, 1988, Volume: 49 Suppl

    Topics: Acute Disease; Anti-Anxiety Agents; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Basal Ga

1988

Other Studies

34 other studies available for lorazepam and Dementia Praecox

ArticleYear
Catatonic Coma in a Patient With Schizophrenia Receiving Palliative Care With Reversal of Symptoms With Lorazepam.
    The primary care companion for CNS disorders, 2023, 02-02, Volume: 25, Issue:1

    Topics: Catatonia; Coma; Humans; Lorazepam; Palliative Care; Schizophrenia

2023
The effects of lorazepam on cortico-striatal connectivity in schizophrenia.
    Schizophrenia research, 2020, Volume: 223

    Topics: Brain Mapping; Corpus Striatum; Humans; Lorazepam; Magnetic Resonance Imaging; Neural Pathways; Schi

2020
Catatonia in a hospitalized patient with COVID-19 and proposed immune-mediated mechanism.
    Brain, behavior, and immunity, 2020, Volume: 89

    Topics: Aged; Atrial Fibrillation; Basal Ganglia; Betacoronavirus; C-Reactive Protein; Catatonia; Coronaviru

2020
Refractory catatonia in old age: a case report.
    Journal of medical case reports, 2021, Aug-14, Volume: 15, Issue:1

    Topics: Aged; Benzodiazepines; Catatonia; Electroconvulsive Therapy; Humans; Lorazepam; Male; Schizophrenia

2021
Attributions to new onset catatonic symptoms, late in the course of chronic schizophrenia.
    Asian journal of psychiatry, 2017, Volume: 30

    Topics: Amlodipine; Antihypertensive Agents; Antipsychotic Agents; Aripiprazole; Catatonia; Chronic Disease;

2017
Two unusual cases of protracted inter-ictal delirium following electroconvulsive therapy.
    Asian journal of psychiatry, 2017, Volume: 29

    Topics: Adult; Antipsychotic Agents; Delirium; Electroconvulsive Therapy; Haloperidol; Humans; Lorazepam; Ma

2017
The catatonic pupil: An unprivileged entity.
    Asian journal of psychiatry, 2018, Volume: 32

    Topics: Adult; Antipsychotic Agents; Catatonia; Female; Humans; Lorazepam; Male; Psychotic Disorders; Pupil

2018
Response of Catatonia to Amisulpride and Lorazepam in an Adolescent with Schizophenia.
    Journal of child and adolescent psychopharmacology, 2018, Volume: 28, Issue:2

    Topics: Adolescent; Amisulpride; Anti-Anxiety Agents; Antipsychotic Agents; Catatonia; Humans; Lorazepam; Ma

2018
Study Enrollment When "Preconsent" Is Utilized for a Randomized Clinical Trial of Two Treatments for Acute Agitation in the Emergency Department.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2019, Volume: 26, Issue:5

    Topics: Adult; Antipsychotic Agents; Bipolar Disorder; Emergency Service, Hospital; Ethics, Research; Female

2019
Neuroleptic malignant syndrome following abrupt anti-cholinergic withdrawal: a case report.
    Asian journal of psychiatry, 2014, Volume: 12

    Topics: Antipsychotic Agents; Cholinergic Antagonists; Female; Humans; Lorazepam; Neuroleptic Malignant Synd

2014
Reduced activation in the ventral striatum during probabilistic decision-making in patients in an at-risk mental state.
    Journal of psychiatry & neuroscience : JPN, 2015, Volume: 40, Issue:3

    Topics: Antidepressive Agents; Brain Mapping; Cross-Sectional Studies; Decision Making; Female; Humans; Hypn

2015
Abnormal GABAergic function and face processing in schizophrenia: A pharmacologic-fMRI study.
    Schizophrenia research, 2015, Volume: 168, Issue:1-2

    Topics: Adult; Brain; Face; Female; gamma-Aminobutyric Acid; Humans; Hypnotics and Sedatives; Image Processi

2015
Acute Urinary Retention and Catatonia in a Schizophrenic Male Patient.
    The primary care companion for CNS disorders, 2016, Nov-10, Volume: 18, Issue:6

    Topics: Antipsychotic Agents; Catatonia; Diagnosis, Differential; GABA Modulators; Humans; Lorazepam; Male;

2016
Psychiatrist accused of dishonesty for prescribing drugs to a patient under a false name.
    BMJ (Clinical research ed.), 2010, Feb-19, Volume: 340

    Topics: Antipsychotic Agents; Deception; England; Female; Haloperidol; Humans; Lorazepam; Prescription Drugs

2010
Familial differential treatment response in schizophrenia--lessons from a case of three affected siblings.
    Pharmacopsychiatry, 2010, Volume: 43, Issue:5

    Topics: Adult; Amisulpride; Antipsychotic Agents; Dibenzothiazepines; Diseases in Twins; Female; Humans; Lor

2010
Acute polydipsia and water intoxication in first episode schizophrenia.
    The Australian and New Zealand journal of psychiatry, 2010, Volume: 44, Issue:5

    Topics: Acute Disease; Adult; Antipsychotic Agents; Dibenzothiazepines; Female; Humans; Hypnotics and Sedati

2010
[Catatonia].
    Nederlands tijdschrift voor geneeskunde, 2010, Volume: 154

    Topics: Adult; Catatonia; Female; Humans; Lorazepam; Male; Mental Disorders; Mood Disorders; Psychotic Disor

2010
Catatonia and encephalopathy associated with paliperidone palmitate.
    Journal of clinical psychopharmacology, 2012, Volume: 32, Issue:2

    Topics: Aged; Antipsychotic Agents; Catatonia; Female; Humans; Isoxazoles; Lorazepam; Male; Neuroleptic Mali

2012
Recurrent clozapine and lorazepam withdrawal psychosis with catatonia.
    The Australian and New Zealand journal of psychiatry, 2012, Volume: 46, Issue:8

    Topics: Adult; Antipsychotic Agents; Catatonia; Clozapine; Disease Management; Female; GABA Modulators; Huma

2012
Elevated quetiapine serum concentrations in a patient treated concomitantly with doxepin, lorazepam, and pantoprazole.
    Journal of clinical psychopharmacology, 2004, Volume: 24, Issue:5

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Antidepressive Agents, Tricyclic; Antipsychotic Agen

2004
Aripiprazole and neuroleptic malignant syndrome.
    International clinical psychopharmacology, 2004, Volume: 19, Issue:6

    Topics: Adult; Antipsychotic Agents; Aripiprazole; Dose-Response Relationship, Drug; Humans; Lorazepam; Male

2004
Methodological concerns in a trial of ziprasidone and olanzapine.
    The American journal of psychiatry, 2005, Volume: 162, Issue:7

    Topics: Anti-Anxiety Agents; Antipsychotic Agents; Benzodiazepines; Bias; Dose-Response Relationship, Drug;

2005
Neuroleptic malignant syndrome precipitated by haloperidol following clozapine discontinuation.
    The Australian and New Zealand journal of psychiatry, 2005, Volume: 39, Issue:10

    Topics: Adult; Anti-Anxiety Agents; Antiparkinson Agents; Antipsychotic Agents; Bromocriptine; Clozapine; Cr

2005
Intramuscular aripiprazole in the control of agitation.
    Journal of psychiatric practice, 2007, Volume: 13, Issue:3

    Topics: Adult; Antipsychotic Agents; Aripiprazole; Arousal; Bipolar Disorder; Dose-Response Relationship, Dr

2007
Switching patients from clozapine to risperidone therapy.
    The American journal of psychiatry, 1995, Volume: 152, Issue:7

    Topics: Antipsychotic Agents; Clonazepam; Clozapine; Drug Administration Schedule; Drug Therapy, Combination

1995
[Benzodiazepine monotherapy in acute schizophrenia].
    Der Nervenarzt, 1994, Volume: 65, Issue:1

    Topics: Acute Disease; Adult; Anti-Anxiety Agents; Diazepam; Humans; Lorazepam; Male; Schizophrenia; Schizop

1994
Flumazenil reversal of benzodiazepine-induced sedation for a patient with severe pre-ECT anxiety.
    Convulsive therapy, 1994, Volume: 10, Issue:1

    Topics: Adult; Anti-Anxiety Agents; Anxiety; Electroconvulsive Therapy; Flumazenil; Humans; Lorazepam; Male;

1994
Somatostatin in the cerebrospinal fluid of schizophrenic patients before and after neuroleptic drug treatment.
    Schizophrenia research, 1993, Volume: 8, Issue:3

    Topics: Adult; Borderline Personality Disorder; Chronic Disease; Clopenthixol; Drug Therapy, Combination; Fe

1993
Catatonia associated with hyponatremia.
    Neuropsychiatry, neuropsychology, and behavioral neurology, 1997, Volume: 10, Issue:1

    Topics: Anti-Anxiety Agents; Catatonia; Humans; Hyponatremia; Lorazepam; Male; Middle Aged; Psychiatric Stat

1997
Seizures after discontinuation of low-dose lorazepam from originally seizure-free clozapine regimen: combined effects?
    The Journal of clinical psychiatry, 1999, Volume: 60, Issue:6

    Topics: Adult; Anti-Anxiety Agents; Clozapine; Dose-Response Relationship, Drug; Drug Administration Schedul

1999
Antioxidants in the treatment of schizophrenia.
    The International journal of neuroscience, 1992, Volume: 62, Issue:1-2

    Topics: Adult; Antioxidants; Ascorbic Acid; Brain; Drug Synergism; Drug Therapy, Combination; Free Radicals;

1992
Use of lorazepam for increased anxiety after neuroleptic dose reduction.
    Hospital & community psychiatry, 1990, Volume: 41, Issue:2

    Topics: Antipsychotic Agents; Anxiety; Combined Modality Therapy; Humans; Lorazepam; Male; Middle Aged; Schi

1990
Lorazepam as an adjunct in the treatment of auditory hallucinations in a schizophrenic patient.
    Journal of clinical psychopharmacology, 1989, Volume: 9, Issue:5

    Topics: Aged; Chronic Disease; Female; Hallucinations; Humans; Lorazepam; Schizophrenia; Schizophrenic Psych

1989
Lorazepam dependence and chronic psychosis.
    The British journal of psychiatry : the journal of mental science, 1985, Volume: 147

    Topics: Adult; Diagnosis, Differential; Humans; Lorazepam; Male; Psychoses, Substance-Induced; Schizophrenia

1985