lorazepam has been researched along with Delirium in 60 studies
Lorazepam: A benzodiazepine used as an anti-anxiety agent with few side effects. It also has hypnotic, anticonvulsant, and considerable sedative properties and has been proposed as a preanesthetic agent.
Delirium: A disorder characterized by CONFUSION; inattentiveness; disorientation; ILLUSIONS; HALLUCINATIONS; agitation; and in some instances autonomic nervous system overactivity. It may result from toxic/metabolic conditions or structural brain lesions. (From Adams et al., Principles of Neurology, 6th ed, pp411-2)
| Excerpt | Relevance | Reference |
|---|---|---|
| "To compare the effect of lorazepam vs placebo as an adjuvant to haloperidol for persistent agitation in patients with delirium in the setting of advanced cancer." | 9.24 | Effect of Lorazepam With Haloperidol vs Haloperidol Alone on Agitated Delirium in Patients With Advanced Cancer Receiving Palliative Care: A Randomized Clinical Trial. ( Amin, S; Breitbart, W; Bruera, E; De La Cruz, M; Delgado-Guay, M; Dibaj, SS; Epner, D; Frisbee-Hume, S; Hall, S; Hess, K; Hui, D; Liu, D; Nguyen, T; Reddy, A; Tanco, K; Vidal, M; Walker, P; Williams, J; Wilson, A; Zhukovsky, DS, 2017) |
| "Of the 103 patients randomized, 63 (31 dexmedetomidine; 32 lorazepam) were admitted with sepsis and 40 (21 dexmedetomidine; 19 lorazepam) without sepsis." | 9.14 | Effect of dexmedetomidine versus lorazepam on outcome in patients with sepsis: an a priori-designed analysis of the MENDS randomized controlled trial. ( Ely, EW; Girard, TD; Herr, DL; Maze, M; McGrane, S; Pandharipande, PP; Sanders, RD; Shintani, AK; Thompson, JL, 2010) |
| "The purpose of this study was to examine the efficacy and side effects of haloperidol, chlorpromazine, and lorazepam for the treatment of the symptoms of delirium in adult AIDS patients in a randomized, double-blind, comparison trial." | 9.08 | A double-blind trial of haloperidol, chlorpromazine, and lorazepam in the treatment of delirium in hospitalized AIDS patients. ( Breitbart, W; Corbera, K; Derevenco, M; Grau, C; Jacobson, P; Lund, S; Marotta, R; Platt, MM; Raymond, S; Weisman, H, 1996) |
| "The use of antipsychotics, with or without lorazepam, during delirium is associated with increased risks of poor outcomes." | 8.02 | Antipsychotics and Lorazepam During Delirium: Are We Harming Older Patients? A Real-Life Data Study. ( Alan, H; Egberts, A; Mattace-Raso, FUS; Ziere, G, 2021) |
| "Practice guidelines recommend the use of low dose haloperidol when medication is needed to treat delirium with acute agitation in hospitalized older people." | 7.79 | Haloperidol overdosing in the treatment of agitated hospitalized older people with delirium: a retrospective chart review from a community teaching hospital. ( Dorokhine, I; Knapp, CM; Musuku, M; Patel, N; Zirker, W, 2013) |
| "Lorazepam administration is an important and potentially modifiable risk factor for transitioning into delirium even after adjusting for relevant covariates." | 7.73 | Lorazepam is an independent risk factor for transitioning to delirium in intensive care unit patients. ( Bernard, GR; Dittus, RS; Ely, EW; Pandharipande, P; Peterson, J; Pun, BT; Shintani, A; Wilkinson, GR, 2006) |
| " During his ED workup, the patient experienced an acute delirium 25 min after being given 2 mg of Lorazepam." | 7.72 | Flumazenil reversal of lorazepam-induced acute delirium. ( Flanigan, J; Olshaker, JS, 2003) |
| "A 53-year-old man with a 3-month addiction to approximately 5 mg/day of triazolam experienced psychosis and delirium following relatively abrupt withdrawal from the drug." | 7.67 | A case of psychosis and delirium following withdrawal from triazolam. ( Capwell, R; Heritch, AJ; Roy-Byrne, PP, 1987) |
| "This was a pre-planned secondary analysis of a double-blind, randomized clinical trial comparing the use of a single dose of lorazepam plus haloperidol versus placebo plus haloperidol in patients with agitated delirium." | 5.41 | Association among rescue neuroleptic use, agitation, and perceived comfort: secondary analysis of a randomized clinical trial on agitated delirium. ( Bruera, E; Chen, M; Hui, D; Tang, M, 2021) |
| "Physostigmine was superior to lorazepam in controlling antimuscarinic delirium and agitation after bolus dosing, and control of delirium after a 4-h infusion." | 5.41 | A randomized trial comparing physostigmine vs lorazepam for treatment of antimuscarinic (anticholinergic) toxidrome. ( Baker, K; Heard, K; Janis, GC; Leonard, J; Mistry, RD; Ng, P; Wang, GS, 2021) |
| "We hypothesized that higher plasma concentrations of lorazepam are associated with increased delirium risk, whereas higher plasma concentrations of dexmedetomidine are associated with reduced delirium risk." | 5.27 | Sedative Plasma Concentrations and Delirium Risk in Critical Illness. ( Ely, EW; Ferrell, BA; Girard, TD; Hughes, CG; Pandharipande, PP; Patel, MB; Scheinin, M; Shintani, AK; Stollings, JL; Thompson, JL; Wilkinson, GR, 2018) |
| "The current study was a secondary analysis of a randomized controlled trial to compare the effect of lorazepam versus placebo as an adjuvant to haloperidol for persistent agitation in patients with delirium." | 5.27 | The minimal clinically important difference of the Richmond Agitation-Sedation Scale in patients with cancer with agitated delirium. ( Arthur, J; Bruera, E; Dalal, S; Dev, R; Dibaj, SS; Hess, K; Hui, D; Reddy, S, 2018) |
| "To compare the effect of lorazepam vs placebo as an adjuvant to haloperidol for persistent agitation in patients with delirium in the setting of advanced cancer." | 5.24 | Effect of Lorazepam With Haloperidol vs Haloperidol Alone on Agitated Delirium in Patients With Advanced Cancer Receiving Palliative Care: A Randomized Clinical Trial. ( Amin, S; Breitbart, W; Bruera, E; De La Cruz, M; Delgado-Guay, M; Dibaj, SS; Epner, D; Frisbee-Hume, S; Hall, S; Hess, K; Hui, D; Liu, D; Nguyen, T; Reddy, A; Tanco, K; Vidal, M; Walker, P; Williams, J; Wilson, A; Zhukovsky, DS, 2017) |
| "Of the 103 patients randomized, 63 (31 dexmedetomidine; 32 lorazepam) were admitted with sepsis and 40 (21 dexmedetomidine; 19 lorazepam) without sepsis." | 5.14 | Effect of dexmedetomidine versus lorazepam on outcome in patients with sepsis: an a priori-designed analysis of the MENDS randomized controlled trial. ( Ely, EW; Girard, TD; Herr, DL; Maze, M; McGrane, S; Pandharipande, PP; Sanders, RD; Shintani, AK; Thompson, JL, 2010) |
| "In mechanically ventilated ICU patients managed with individualized targeted sedation, use of a dexmedetomidine infusion resulted in more days alive without delirium or coma and more time at the targeted level of sedation than with a lorazepam infusion." | 5.12 | Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial. ( Bernard, GR; Deppen, SA; Dittus, RS; Ely, EW; Girard, TD; Herr, DL; Jackson, JC; Maze, M; Miller, RR; Pandharipande, PP; Pun, BT; Shintani, AK; Stiles, RA; Thompson, JL, 2007) |
| "The purpose of this study was to examine the efficacy and side effects of haloperidol, chlorpromazine, and lorazepam for the treatment of the symptoms of delirium in adult AIDS patients in a randomized, double-blind, comparison trial." | 5.08 | A double-blind trial of haloperidol, chlorpromazine, and lorazepam in the treatment of delirium in hospitalized AIDS patients. ( Breitbart, W; Corbera, K; Derevenco, M; Grau, C; Jacobson, P; Lund, S; Marotta, R; Platt, MM; Raymond, S; Weisman, H, 1996) |
| " All of the participants had delirium, were treated with haloperidol, and were randomised to receive either lorazepam or placebo in combination with it." | 5.05 | Benzodiazepines for treatment of patients with delirium excluding those who are cared for in an intensive care unit. ( Chen, J; Jin, Y; Li, N; Li, Y; Ma, J; Mu, W; Shang, HC; Si, JH; Wang, J; Zheng, R, 2020) |
| "This network meta-analysis demonstrated that haloperidol plus lorazepam might be the best treatment and ramelteon the best preventive medicine for delirium." | 5.01 | Association of Delirium Response and Safety of Pharmacological Interventions for the Management and Prevention of Delirium: A Network Meta-analysis. ( Carvalho, AF; Chen, TY; Chen, YW; Chu, CS; Hsu, CY; Liang, CS; Lin, PY; Matsuoka, YJ; Stubbs, B; Su, KP; Tseng, PT; Tu, YK; Wada, S; Wu, YC; Yeh, TC, 2019) |
| " In this trial, comparing the effect of the benzodiazepine, lorazepam, with dexmedetomidine, a selective alpha-2-adrenergic receptor agonist, on delirium among mechanically ventilated intensive care unit patients, dexmedetomidine treatment was associated with an increased number of delirium- and coma-free days compared with lorazepam treated patients (dexmedetomidine patients, average seven days; lorazepam patients, average three days; P = 0." | 4.85 | Benzodiazepines for delirium. ( Areosa Sastre, A; Lonergan, E; Luxenberg, J, 2009) |
| " In this trial, comparing the effect of the benzodiazepine, lorazepam, with dexmedetomidine, a selective alpha-2-adrenergic receptor agonist, on delirium among mechanically ventilated intensive care unit patients, dexmedetomidine treatment was associated with an increased number of delirium- and coma-free days compared with lorazepam treated patients (dexmedetomidine patients, average seven days; lorazepam patients, average three days; P = 0." | 4.85 | Benzodiazepines for delirium. ( Areosa Sastre, A; Lonergan, E; Luxenberg, J; Wyller, TB, 2009) |
| "The data from one study of 30 patients would perhaps suggest that haloperidol is the most suitable drug therapy for the treatment of patients with delirium near the end of life." | 4.82 | Drug therapy for delirium in terminally ill patients. ( Jackson, KC; Lipman, AG, 2004) |
| "The use of antipsychotics, with or without lorazepam, during delirium is associated with increased risks of poor outcomes." | 4.02 | Antipsychotics and Lorazepam During Delirium: Are We Harming Older Patients? A Real-Life Data Study. ( Alan, H; Egberts, A; Mattace-Raso, FUS; Ziere, G, 2021) |
| "The World Health Organization recommends that anxiety, depression, agitation and delirium at end of life should be treated with drugs such as lorazepam, diazepam, midazolam and haloperidol." | 3.83 | Look again at psychedelic drugs. ( Cameron, R, 2016) |
| "Practice guidelines recommend the use of low dose haloperidol when medication is needed to treat delirium with acute agitation in hospitalized older people." | 3.79 | Haloperidol overdosing in the treatment of agitated hospitalized older people with delirium: a retrospective chart review from a community teaching hospital. ( Dorokhine, I; Knapp, CM; Musuku, M; Patel, N; Zirker, W, 2013) |
| " Delirium and daily dosage of lorazepam are the factors independently associated to extremely severe REM sleep reduction." | 3.77 | Sleep disturbances in the critically ill patients: role of delirium and sedative agents. ( Bosma, K; Braghiroli, A; Locane, MD; Mascia, L; Ranieri, VM; Trompeo, AC; Vidi, Y, 2011) |
| "Lorazepam administration is an important and potentially modifiable risk factor for transitioning into delirium even after adjusting for relevant covariates." | 3.73 | Lorazepam is an independent risk factor for transitioning to delirium in intensive care unit patients. ( Bernard, GR; Dittus, RS; Ely, EW; Pandharipande, P; Peterson, J; Pun, BT; Shintani, A; Wilkinson, GR, 2006) |
| " During his ED workup, the patient experienced an acute delirium 25 min after being given 2 mg of Lorazepam." | 3.72 | Flumazenil reversal of lorazepam-induced acute delirium. ( Flanigan, J; Olshaker, JS, 2003) |
| "More than 2,000 medically ill patients with delirium have been treated by intravenous administration of a combination of haloperidol and lorazepam." | 3.67 | Emergency intravenous sedation of the delirious, medically ill patient. ( Adams, F, 1988) |
| "A 53-year-old man with a 3-month addiction to approximately 5 mg/day of triazolam experienced psychosis and delirium following relatively abrupt withdrawal from the drug." | 3.67 | A case of psychosis and delirium following withdrawal from triazolam. ( Capwell, R; Heritch, AJ; Roy-Byrne, PP, 1987) |
| "Delirium is a syndrome characterised by an acute disturbance of attention and awareness which develops over a short time period and fluctuates in severity over the course of the day." | 2.66 | Drug therapy for delirium in terminally ill adults. ( Candy, B; Finucane, AM; Jones, L; Leurent, B; Sampson, EL; Stone, P; Tookman, A, 2020) |
| "Treatment with lorazepam only should be avoided." | 2.49 | [Pharmacological treatment of delirium in palliative care patients. A systematic literature review]. ( Golla, H; Perrar, KM; Voltz, R, 2013) |
| "Catatonia is often a prominent feature of the syndrome." | 2.49 | Delirious mania: detection, diagnosis, and clinical management in the acute setting. ( Bobo, WV; Heckers, S; Jacobowski, NL, 2013) |
| "The prognosis of CCI patients with coma or delirium has not yet been thoroughly studied, but preliminary studies suggest this population is at high risk for detrimental outcomes associated with acute brain dysfunction." | 2.48 | Brain dysfunction in patients with chronic critical illness. ( Girard, TD, 2012) |
| "Delirium is a syndrome characterised by a disturbance of consciousness (often fluctuating), cognition and perception." | 2.48 | Drug therapy for delirium in terminally ill adult patients. ( Candy, B; Jackson, KC; Jones, L; King, M; Leurent, B; Tookman, A, 2012) |
| "Delirium is defined by a fluctuating level of attentiveness and has been associated with increased ICU mortality and poor cognitive outcomes in both general ICU and neurocritical care populations." | 2.47 | Delirium and sedation in the ICU. ( Frontera, JA, 2011) |
| "Delirium is the second most common psychiatric diagnosis among hospitalized elderly cancer patients." | 2.38 | Delirium in cancer patients. ( Holland, J; Stiefel, F, 1991) |
| "Delirium is the most common neuropsychiatric complication of hospitalized AIDS patients." | 2.38 | Management of delirium in terminally ill AIDS patients. ( Fernandez, F; Levy, JK; Mansell, PW, 1989) |
| "Attribution of catatonia to a psychiatric etiology was associated with significantly less diagnostic workup." | 1.46 | Suspected Delirium Predicts the Thoroughness of Catatonia Evaluation. ( Coffey, MJ; Cooper, JJ; Jacobson, KC; Llesuy, JR, 2017) |
| "To determine the dosing patterns and total doses of fentanyl, lorazepam, and haloperidol according to nursing shift in a cohort of older patients in a medical intensive care unit." | 1.39 | Patterns of opiate, benzodiazepine, and antipsychotic drug dosing in older patients in a medical intensive care unit. ( Akgün, KM; Araujo, KL; Bramley, K; Murphy, TE; Pisani, MA; Vest, MT, 2013) |
| "Delirium is still one of the most common and distressing symptoms in palliative care patients." | 1.38 | Reversible delirium in an advanced cancer patient. ( Jagsch, C; Kierner, KA; Watzke, HH, 2012) |
| "However, interictal delirium is uncommon in absence of risk factors." | 1.38 | Delayed onset and prolonged interictal delirium following electroconvulsive therapy. ( Praharaj, SK; Selvaraj, AG, 2012) |
| "In elderly people a delirium is often misinterpreted as dementia." | 1.37 | [Delirium induced by drug treatment]. ( Back, C; Haen, E; Wittmann, M, 2011) |
| "Drug-induced delirium is a common matter in the elderly and anticholinergics, together with a number of different drugs, may significantly contribute to the delirium onset, especially in demented people." | 1.34 | Anticholinergic drug-induced delirium in an elderly Alzheimer's dementia patient. ( Cotroneo, A; De Fazio, P; De Fazio, S; De Sarro, G; Gallelli, L; Gareri, P; Lacava, R, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (10.00) | 18.7374 |
| 1990's | 4 (6.67) | 18.2507 |
| 2000's | 17 (28.33) | 29.6817 |
| 2010's | 27 (45.00) | 24.3611 |
| 2020's | 6 (10.00) | 2.80 |
| Authors | Studies |
|---|---|
| Finucane, AM | 1 |
| Jones, L | 2 |
| Leurent, B | 2 |
| Sampson, EL | 1 |
| Stone, P | 1 |
| Tookman, A | 2 |
| Candy, B | 2 |
| Li, Y | 1 |
| Ma, J | 1 |
| Jin, Y | 1 |
| Li, N | 1 |
| Zheng, R | 1 |
| Mu, W | 1 |
| Wang, J | 1 |
| Si, JH | 1 |
| Chen, J | 1 |
| Shang, HC | 1 |
| Egberts, A | 1 |
| Alan, H | 1 |
| Ziere, G | 1 |
| Mattace-Raso, FUS | 1 |
| Wang, GS | 1 |
| Baker, K | 1 |
| Ng, P | 1 |
| Janis, GC | 1 |
| Leonard, J | 1 |
| Mistry, RD | 1 |
| Heard, K | 1 |
| Tang, M | 1 |
| Chen, M | 1 |
| Bruera, E | 3 |
| Hui, D | 3 |
| Reinfeld, S | 1 |
| Yacoub, A | 1 |
| Frisbee-Hume, S | 1 |
| Wilson, A | 1 |
| Dibaj, SS | 2 |
| Nguyen, T | 1 |
| De La Cruz, M | 1 |
| Walker, P | 1 |
| Zhukovsky, DS | 1 |
| Delgado-Guay, M | 1 |
| Vidal, M | 1 |
| Epner, D | 1 |
| Reddy, A | 1 |
| Tanco, K | 1 |
| Williams, J | 1 |
| Hall, S | 1 |
| Liu, D | 1 |
| Hess, K | 2 |
| Amin, S | 1 |
| Breitbart, W | 2 |
| Kathirvel, N | 1 |
| Ghosh, AK | 1 |
| Stollings, JL | 1 |
| Thompson, JL | 3 |
| Ferrell, BA | 1 |
| Scheinin, M | 1 |
| Wilkinson, GR | 2 |
| Hughes, CG | 1 |
| Shintani, AK | 3 |
| Ely, EW | 5 |
| Girard, TD | 4 |
| Pandharipande, PP | 3 |
| Patel, MB | 1 |
| Arthur, J | 1 |
| Dev, R | 1 |
| Dalal, S | 1 |
| Reddy, S | 1 |
| Shrikant Kulkarni, N | 1 |
| Wu, YC | 1 |
| Tseng, PT | 1 |
| Tu, YK | 1 |
| Hsu, CY | 1 |
| Liang, CS | 1 |
| Yeh, TC | 1 |
| Chen, TY | 1 |
| Chu, CS | 1 |
| Matsuoka, YJ | 1 |
| Stubbs, B | 1 |
| Carvalho, AF | 1 |
| Wada, S | 1 |
| Lin, PY | 1 |
| Chen, YW | 1 |
| Su, KP | 1 |
| Perrar, KM | 1 |
| Golla, H | 1 |
| Voltz, R | 1 |
| Zirker, W | 1 |
| Dorokhine, I | 1 |
| Knapp, CM | 1 |
| Patel, N | 1 |
| Musuku, M | 1 |
| Pisani, MA | 1 |
| Bramley, K | 1 |
| Vest, MT | 1 |
| Akgün, KM | 1 |
| Araujo, KL | 1 |
| Murphy, TE | 1 |
| del Río-Casanova, L | 1 |
| Portela, B | 1 |
| Díaz-Llenderrozas, F | 1 |
| Cameron, R | 1 |
| Gagnon, DJ | 1 |
| Fontaine, GV | 1 |
| Smith, KE | 1 |
| Riker, RR | 1 |
| Miller, RR | 3 |
| Lerwick, PA | 1 |
| Lucas, FL | 1 |
| Dziodzio, JT | 1 |
| Sihler, KC | 1 |
| Fraser, GL | 1 |
| Llesuy, JR | 1 |
| Coffey, MJ | 1 |
| Jacobson, KC | 1 |
| Cooper, JJ | 1 |
| Lonergan, E | 2 |
| Luxenberg, J | 2 |
| Areosa Sastre, A | 2 |
| Wyller, TB | 1 |
| Sanders, RD | 1 |
| McGrane, S | 1 |
| Herr, DL | 2 |
| Maze, M | 2 |
| Kress, JP | 1 |
| Danivas, V | 1 |
| Behere, RV | 1 |
| Varambally, S | 1 |
| Rao, NP | 1 |
| Venkatasubramanian, G | 1 |
| Gangadhar, BN | 1 |
| Back, C | 1 |
| Wittmann, M | 1 |
| Haen, E | 1 |
| Frontera, JA | 1 |
| Watson, PL | 1 |
| Trompeo, AC | 1 |
| Vidi, Y | 1 |
| Locane, MD | 1 |
| Braghiroli, A | 1 |
| Mascia, L | 1 |
| Bosma, K | 1 |
| Ranieri, VM | 1 |
| Kashyap, GL | 1 |
| Patel, AG | 1 |
| Kierner, KA | 1 |
| Jagsch, C | 1 |
| Watzke, HH | 1 |
| Pittermann, P | 1 |
| Gabriel, S | 1 |
| Röschke, J | 1 |
| Selvaraj, AG | 1 |
| Praharaj, SK | 1 |
| Jackson, KC | 2 |
| King, M | 1 |
| Jacobowski, NL | 1 |
| Heckers, S | 1 |
| Bobo, WV | 1 |
| Olshaker, JS | 1 |
| Flanigan, J | 1 |
| Rosenberg, MH | 1 |
| Deerfield, LJ | 1 |
| Baruch, EM | 1 |
| Lipman, AG | 1 |
| Nakasato, Y | 1 |
| Servat, J | 1 |
| Amador, F | 1 |
| Teasdale, TA | 1 |
| Pruett, JR | 1 |
| Rizvi, ST | 1 |
| Pandharipande, P | 1 |
| Shintani, A | 1 |
| Peterson, J | 1 |
| Pun, BT | 2 |
| Dittus, RS | 2 |
| Bernard, GR | 2 |
| Inouye, SK | 1 |
| Seitz, D | 1 |
| Gill, SS | 1 |
| Gareri, P | 1 |
| De Fazio, P | 1 |
| Cotroneo, A | 1 |
| Lacava, R | 1 |
| Gallelli, L | 1 |
| De Fazio, S | 1 |
| De Sarro, G | 1 |
| Carroll, BT | 1 |
| Thomas, C | 1 |
| Tugrul, KC | 1 |
| Coconcea, C | 1 |
| Goforth, HW | 1 |
| Jackson, JC | 1 |
| Deppen, SA | 1 |
| Stiles, RA | 1 |
| Barletta, JF | 1 |
| Devlin, JW | 1 |
| Dunn, WF | 1 |
| Adams, SC | 1 |
| Adams, RW | 1 |
| Marotta, R | 1 |
| Platt, MM | 1 |
| Weisman, H | 1 |
| Derevenco, M | 1 |
| Grau, C | 1 |
| Corbera, K | 1 |
| Raymond, S | 1 |
| Lund, S | 1 |
| Jacobson, P | 1 |
| Galen, DM | 1 |
| Beck, M | 1 |
| Buchbinder, D | 1 |
| Weiss, AP | 1 |
| Murray, GB | 1 |
| Dundee, JW | 1 |
| Lilburn, JK | 1 |
| Moss, JH | 1 |
| Stiefel, F | 1 |
| Holland, J | 1 |
| Adams, F | 2 |
| Fernandez, F | 2 |
| Levy, JK | 1 |
| Mansell, PW | 1 |
| Heritch, AJ | 1 |
| Capwell, R | 1 |
| Roy-Byrne, PP | 1 |
| Andersson, BS | 1 |
| Modell, JG | 1 |
| Lenox, RH | 1 |
| Weiner, S | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Open-label Randomized Controlled Trial of Oral Transmucosal Haloperidol and Olanzapine in the Treatment of Terminal Delirium[NCT04750395] | Phase 2 | 80 participants (Anticipated) | Interventional | 2021-09-01 | Recruiting | ||
| A Preliminary Double-Blind Randomized Controlled Trial of Haloperidol and Lorazepam for Delirium in Patients With Advanced Cancer Admitted to a Palliative Care Unit[NCT01949662] | Phase 2 | 93 participants (Actual) | Interventional | 2014-01-31 | Active, not recruiting | ||
| HALO Trial: Haloperidol vs Olanzapine in Hyperactive Delirium in Palliative Care Patients; A Multi-Centre, Randomised-Controlled Trial[NCT04833023] | Phase 3 | 72 participants (Anticipated) | Interventional | 2022-05-18 | Recruiting | ||
| A Randomized, Double-blind Trial in Ventilated ICU Patients Comparing Treatment With an Alpha2 Agonist Versus a Gamma Aminobutyric Acid (GABA)-Agonist to Determine Delirium Rates, Efficacy of Sedation, Analgesia and Discharge Cognitive Status[NCT00095251] | Phase 2 | 100 participants (Anticipated) | Interventional | 2004-08-31 | Completed | ||
| PRO-DEFENSE: Propofol Versus Dexmedetomidine for Sedation in Mechanically Ventilated Patients With Sepsis[NCT02203019] | Phase 4 | 36 participants (Actual) | Interventional | 2014-08-31 | Completed | ||
| Multicentric, Single Blind, Randomized Controlled Trial on Enteral Sedation Versus Intravenous Sedation in Critically Ill High-risk ICU Patients[NCT01360346] | Phase 3 | 300 participants (Anticipated) | Interventional | 2012-01-31 | Recruiting | ||
| Pain, Agitation and Delirium Protocol in Ventilated Patients in the Duke CICU[NCT02903407] | Phase 4 | 7 participants (Actual) | Interventional | 2017-09-01 | Terminated (stopped due to All enrolled participants completed the study protocol but the study was terminated prior to the goal number of participants due to low recruitment) | ||
| Impact of Night-time Dexmedetomidine-esketamine Infusion on Sleep Quality of Patients With Mechanical Ventilation in ICU: a Randomized Controlled Trial[NCT05718024] | Phase 4 | 174 participants (Anticipated) | Interventional | 2023-12-31 | Not yet recruiting | ||
| Impact of Dexmedetomidine Supplemented Analgesia on Sleep Quality in Elderly Patients After Major Surgery: A Randomized, Double-blind, and Placebo-controlled Pilot Study[NCT03117790] | Phase 4 | 118 participants (Actual) | Interventional | 2017-06-26 | Completed | ||
| Impact of Low-Dose Dexmedetomidine on Sleep Quality in Mechanical Ventilation Patients After Surgery in Intensive Care Unit: a Pilot Randomized, Double-Blind, Placebo-Controlled Trial[NCT03335527] | Phase 4 | 80 participants (Actual) | Interventional | 2017-11-17 | Completed | ||
| Effect of Flumazenil on Hypoactive Delirium in the ICU: A Double-Blind, Placebo-Controlled Pilot Study[NCT02899156] | Phase 4 | 22 participants (Actual) | Interventional | 2016-03-31 | Terminated (stopped due to A planned interim analysis led to the trial being stopped early based on the observed size effect and power analysis.) | ||
| A Randomized Control Trial Using the BIS Monitor to Avoid Over Sedation and Prolonged Neuropsychological Deficits in Mechanically Ventilated ICU Patients[NCT00469482] | 28 participants (Actual) | Interventional | 2007-06-30 | Completed | |||
| Haloperidol vs Olanzapine for the Management of ICU Delirium: A Randomized Clinical Trial[NCT00833300] | 200 participants (Anticipated) | Interventional | 2008-06-30 | Terminated | |||
| Randomized, Placebo Controlled, Pilot Trial of Statin Use in Burn Patients[NCT00978419] | Phase 2 | 40 participants (Actual) | Interventional | 2010-03-31 | Completed | ||
| A Randomized Controlled Trial To Assess Risk of Delirium in Older Adults Undergoing Hip Fracture Surgery With Spinal or General Anesthesia[NCT02190903] | 15 participants (Actual) | Interventional | 2013-10-31 | Completed | |||
| Evaluation of the CogMe Technology Platform for the Prevention and Early Detection of Delirium Among Older Patients in an Acute Hospital Setting: A Proof of Concept Study[NCT05311761] | 100 participants (Anticipated) | Interventional | 2022-03-01 | Recruiting | |||
| Tailored Patient Management Guided With Absolute Cerebral Oximetry to Prevent Neurocognitive Injury in Elderly Patients Undergoing Cardiac Surgery.[NCT00991328] | Phase 3 | 15 participants (Actual) | Interventional | 2009-09-30 | Terminated (stopped due to low enrollment) | ||
| Non-Invasive Brain Stimulation and Delirium[NCT03518996] | 0 participants (Actual) | Interventional | 2018-09-01 | Withdrawn (stopped due to No Participants Enrolled) | |||
| Continuous Cerebral Autoregulation Monitoring to Reduce Brain Injury From Cardiac Surgery[NCT00981474] | 460 participants (Actual) | Interventional | 2009-09-01 | Completed | |||
| Dexmedetomidine and IV Acetaminophen for the Prevention of Postoperative Delirium Following Cardiac Surgery in Adult Patients 60 Years of Age and Older[NCT02546765] | Phase 4 | 140 participants (Actual) | Interventional | 2015-10-31 | Completed | ||
| Effects of Two Different Anesthesia-analgesia Methods on the Incidence of Postoperative Delirium: a Multicenter, Randomized Controlled Trial[NCT01661907] | 1,800 participants (Actual) | Interventional | 2011-11-21 | Completed | |||
| Prevention of Delirium in Inpatients Utilizing Melatonin[NCT02654314] | Phase 3 | 277 participants (Actual) | Interventional | 2016-07-31 | Terminated (stopped due to Lack of resources to complete the study. Descriptive statistics for the outcome measures collected are provided.) | ||
| Cukurova University Faculty of Medicine[NCT02360982] | 120 participants (Actual) | Observational | 2012-03-31 | Completed | |||
| Impact of Dexmedetomidine Supplemented Analgesia on Long-term Survival in Elderly Patients After Cancer Surgery: a Multicenter Randomized Controlled Trial[NCT03012971] | 1,500 participants (Actual) | Interventional | 2017-01-06 | Active, not recruiting | |||
| Low-dose Dexmedetomidine for Delirium Prevention in Mechanically Ventilated Patients in Intensive Care Unit: a Multicenter, Randomised, Double-blinded, Placebo-controlled Trial[NCT03172897] | Phase 4 | 260 participants (Anticipated) | Interventional | 2017-08-20 | Suspended (stopped due to The trial was stopped because of difficulty in recruiting patients (another trial had similar inclusion/exclusion criteria). No patients was recruited in this trial.) | ||
| Phenobarbital Versus Ativan for Refractory Alcohol Withdrawal Treatment in the Intensive Care Unit[NCT04156464] | Phase 4 | 142 participants (Anticipated) | Interventional | 2020-07-06 | Recruiting | ||
| Dynamic Light Application to Prevent ICU Acquired Delirium[NCT01274819] | 1,000 participants (Actual) | Interventional | 2011-07-31 | Completed | |||
| Impact of Dexmedetomidine Supplemented Analgesia on Incidence of Delirium in Elderly Patients After Cancer Surgery: a Multicenter Randomized Controlled Trial[NCT03012984] | 1,500 participants (Actual) | Interventional | 2017-01-06 | Completed | |||
| Effect of Low-dose Dexmedetomidine on Postoperative Delirium in Patients After Cardiac Surgery: A Multicenter, Double-blinded, Randomized Controlled Trial[NCT03624595] | 502 participants (Anticipated) | Interventional | 2019-04-16 | Active, not recruiting | |||
| Awakening-Breathing Coordination, Delirium Monitoring/Management & Early Mobility (ABCDE) Protocol[NCT01413009] | 200 participants (Actual) | Observational | 2010-12-29 | Completed | |||
| The Effect of Steroid on Reducing Facial Swelling After Orthognathic Surgery[NCT01431014] | Phase 4 | 56 participants (Actual) | Interventional | 2011-08-31 | Completed | ||
| Prospective Evaluation of Perioperative Steroid Dosing on Postsurgical Edema in Orthognathic Surgery[NCT03190642] | Phase 4 | 180 participants (Actual) | Interventional | 2018-01-01 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Absolute score of Richmond Agitation-Sedation Scale at 8 hr, points. Richmond Agitation-Sedation Score ranged from -5 (unarousable) to +4 (very agitated) , where 0 denotes a calm and alert patient. (NCT01949662)
Timeframe: 8 hours
| Intervention | score on a scale (Mean) |
|---|---|
| Intervention Group (Lorazepam & Haloperidol) | -2.5 |
| Control Group (Placebo & Haloperidol) | -0.7 |
The primary outcome was change in Richmond Agitation-Sedation Scale score from baseline to 8 hours after treatment administration. Richmond Agitation-Sedation Score ranged from -5 (unarousable) to +4 (very agitated) , where 0 denotes a calm and alert patient. (NCT01949662)
Timeframe: Baseline to 8 hours
| Intervention | score on a scale (Mean) |
|---|---|
| Intervention Group (Lorazepam & Haloperidol) | -4.1 |
| Control Group (Placebo & Haloperidol) | -2.3 |
Change in Richmond Agitation-Sedation Scale score from baseline to 30 min. Richmond Agitation-Sedation Score ranged from -5 (unarousable) to +4 (very agitated) , where 0 denotes a calm and alert patient. (NCT01949662)
Timeframe: Baseline to 30 minutes
| Intervention | score on a scale (Mean) |
|---|---|
| Intervention Group (Lorazepam & Haloperidol) | -3.6 |
| Control Group (Placebo & Haloperidol) | -1.6 |
Number of participants with Richmond Agitation-Sedation Scale score >=1 within 8 hr. Richmond Agitation-Sedation Score ranged from -5 (unarousable) to +4 (very agitated) , where 0 denotes a calm and alert patient. (NCT01949662)
Timeframe: Baseline to 8 hours
| Intervention | Participants (Count of Participants) |
|---|---|
| Intervention Group (Lorazepam & Haloperidol) | 8 |
| Control Group (Placebo & Haloperidol) | 22 |
Number of days patient requires mechanical ventilation (NCT02203019)
Timeframe: Up to 28 days
| Intervention | days (Median) |
|---|---|
| Propofol | 5 |
| Dexmedetomidine | 3 |
Number of days patient stays in the MICU (NCT02203019)
Timeframe: Up to 28 Days
| Intervention | days (Median) |
|---|---|
| Propofol | 6 |
| Dexmedetomidine | 5 |
Number of days the patient requires intravenous vasopressors (NCT02203019)
Timeframe: Up to 28 Days
| Intervention | days (Median) |
|---|---|
| Propofol | 0 |
| Dexmedetomidine | 2 |
Number of patients who die within 28 days after randomization (NCT02203019)
Timeframe: Up to 28 Days
| Intervention | Participants (Count of Participants) |
|---|---|
| Propofol | 8 |
| Dexmedetomidine | 9 |
Index hospitalization length of stay in days (NCT02903407)
Timeframe: One month or hospital discharge, whichever time point comes first
| Intervention | Days (Median) |
|---|---|
| Midazolam | 19.5 |
| Propofol or Dexmedetomidine | 30.0 |
All-cause mortality during the hospitalization (NCT02903407)
Timeframe: One month or hospital discharge, whichever time point comes first
| Intervention | participants (Number) |
|---|---|
| Midazolam | 1 |
| Propofol or Dexmedetomidine | 1 |
Number of days of admission to the CICU during the index hospitalization (NCT02903407)
Timeframe: One month or hospital discharge, whichever time point comes first
| Intervention | Days (Median) |
|---|---|
| Midazolam | 4.1 |
| Propofol or Dexmedetomidine | 10.0 |
The number of days alive and free from delirium or coma during admission will be evaluated among patients with CAM-ICU documented (NCT02903407)
Timeframe: One month or hospital discharge, whichever time point comes first
| Intervention | Days (Median) |
|---|---|
| Midazolam | 14.0 |
The time (in days) from when the clinical care team documents a decision to pursue extubation until the time the patient was extubated (NCT02903407)
Timeframe: One month or hospital discharge, whichever time point comes first
| Intervention | Days (Median) |
|---|---|
| Midazolam | 0 |
| Propofol or Dexmedetomidine | 0 |
Following ICU discharge, patient charts will be reviewed to evaluate whether they required reintubation. If so, will determine whether necessity of reintubation was related to delirium. (NCT02903407)
Timeframe: One month or hospital discharge, whichever time point comes first
| Intervention | Participants (Count of Participants) |
|---|---|
| Midazolam | 0 |
| Propofol or Dexmedetomidine | 1 |
Patients will be monitored for bradycardia which may be associated with sedation drug. Average heart rate before, during and after use of drug will be recorded for each patient. (NCT02903407)
Timeframe: One month or hospital discharge, whichever time point comes first
| Intervention | Participants (Count of Participants) |
|---|---|
| Midazolam | 0 |
| Propofol or Dexmedetomidine | 0 |
Will use the Confusion Assessment Method for the ICU (CAM-ICU) to assess presence of delirium as per standard of care by nurses in the CICU. Patients with CAM-ICU data recorded will be included. (NCT02903407)
Timeframe: One month or hospital discharge, whichever time point comes first
| Intervention | Participants (Count of Participants) |
|---|---|
| Midazolam | 1 |
Patients will be monitored for increased pressor requirement during the CICU stay (NCT02903407)
Timeframe: One month or hospital discharge, whichever time point comes first
| Intervention | Participants (Count of Participants) |
|---|---|
| Midazolam | 2 |
| Propofol or Dexmedetomidine | 2 |
Days requiring mechanical ventilation during the initial episode of intubation during the hospitalization (NCT02903407)
Timeframe: One month or hospital discharge, whichever time point comes first
| Intervention | Days (Median) |
|---|---|
| Midazolam | 2.5 |
| Propofol or Dexmedetomidine | 6.8 |
Will use the CPOT (Critical-Care Pain Observation Tool) score to assess pain level as per standard of care by nurses in the CICU. The CPOT has a range of 0 to 8. A CPOT score of ≤ 2 = minimal to no pain present and >2 = unacceptable level of pain. Data that is recorded will be evaluated following discharge. (NCT02903407)
Timeframe: One month or hospital discharge, whichever time point comes first
| Intervention | score on a scale (Median) |
|---|---|
| Midazolam | 0.0 |
| Propofol or Dexmedetomidine | 0.0 |
Will use RASS (Richmond Agitation and Sedation Scale) to assess level of sedation as per standard of care by nurses in the CICU. Data that is recorded will be evaluated following discharge. The RASS ranges from -5 (unrousable) to +4 (combative) and 0 (zero) = alert and calm and goal sedation is considered a RASS level of 0 to -2. (NCT02903407)
Timeframe: One month or hospital discharge, whichever time point comes first
| Intervention | percentage of time (Median) |
|---|---|
| Midazolam | 63.3 |
| Propofol or Dexmedetomidine | 63.2 |
The duration, in days, from withdrawal of sedation for mechanical ventilation until the time of discharge from the ICU (NCT02903407)
Timeframe: One month or hospital discharge, whichever time point comes first
| Intervention | Days (Median) |
|---|---|
| Midazolam | 1.6 |
| Propofol or Dexmedetomidine | 5.6 |
average duration of time patient was randomized to each infusion up to 72 hours (NCT02899156)
Timeframe: up to 72 hours after the start of the infusion
| Intervention | hours (Mean) |
|---|---|
| Flumazenil Group | 54.8 |
| Placebo Group | 58.2 |
average maximum rate (ml/hr) during the 72 hours after study infusion (NCT02899156)
Timeframe: up to 72 hours after the start of the infusion
| Intervention | milliliters per hour (Mean) |
|---|---|
| Flumazenil Group | 5 |
| Placebo Group | 5.2 |
length of time that the patient was admitted to an intensive care unit service during the hospital stay (NCT02899156)
Timeframe: duration of admission to the intensive care unit
| Intervention | days (Mean) |
|---|---|
| Flumazenil Group | 7.8 |
| Placebo Group | 7 |
Defined by the number of days in the 14-day period after randomization that the patient was alive and not delirious (i.e. CAM-ICU negative). Zero delirium-free days will be observed for patients that die within the 14-day period. (NCT02899156)
Timeframe: up to 14 days after randomization
| Intervention | days (Median) |
|---|---|
| Flumazenil Group | 12.7 |
| Placebo Group | 9.2 |
number of days within the first 28 days after enrollment that the patient was free from needing mechanical ventilation (NCT02899156)
Timeframe: up to 28 days after randomization
| Intervention | days (Mean) |
|---|---|
| Flumazenil Group | 23.6 |
| Placebo Group | 24.9 |
defined by the proportion of patients who were delirium free at 14 days after randomization (NCT02899156)
Timeframe: up to 14 days after randomization
| Intervention | Participants (Count of Participants) |
|---|---|
| Flumazenil Group | 9 |
| Placebo Group | 7 |
number of times that a RASS score of + 2 to +4 occurred that did not resolve with decreasing study infusion (NCT02899156)
Timeframe: up to 72 hours after the start of the infusion
| Intervention | Participants (Count of Participants) |
|---|---|
| Flumazenil Group | 0 |
| Placebo Group | 0 |
Delirium will be assessed by the Confusion Assessment Method Instrument (CAM), a validated method of assessing delirium based on the presence of both (1) an acute onset of signs and symptoms with a fluctuating course AND (2) inattention; PLUS (3) disorganized thinking OR (4) an altered level of consciousness. (NCT02190903)
Timeframe: Up to 5 days post hip fracture surgery
| Intervention | Participants (Count of Participants) |
|---|---|
| General Endotracheal Anesthesia | 2 |
| Regional (Spinal) Anesthesia | 0 |
Subject developed acute kidney injury within 7 days after surgical procedure. Based on Kidney disease: Improving Global Outcomes (KDIGO) classification system. (NCT00981474)
Timeframe: 7 days after surgery
| Intervention | Participants (Count of Participants) |
|---|---|
| Control | 56 |
| Intervention | 62 |
The composite neurological outcome was composed of clinical stroke, or new ischemic lesions detected on postoperative brain diffusion weighted magnetic resonance imaging(DWI), or cognitive decline from baseline to 4-6 weeks after surgery. (NCT00981474)
Timeframe: Up to 6 weeks post-operative
| Intervention | Participants (Count of Participants) |
|---|---|
| Usual Care Group (Control) | 79 |
| Autoregulation Group | 70 |
Procedural insertion of intra-aortic balloon pump within 7 days after surgical procedure (NCT00981474)
Timeframe: 7 days after surgery
| Intervention | Participants (Count of Participants) |
|---|---|
| Control | 19 |
| Intervention | 14 |
Subjects need for mechanical lung ventilation more than 24 hours after planned surgical procedure. (NCT00981474)
Timeframe: Up to 28 days after surgery.
| Intervention | Participants (Count of Participants) |
|---|---|
| Control | 22 |
| Intervention | 13 |
Subject death within 28 days after surgical procedure (NCT00981474)
Timeframe: 28 days
| Intervention | Participants (Count of Participants) |
|---|---|
| Control | 12 |
| Intervention | 5 |
Use of multiple inotropic drugs greater than 24 hours after the planned surgical procedure until discharge from the hospital. (NCT00981474)
Timeframe: 7 days after surgery
| Intervention | participants (Number) |
|---|---|
| Usual Care Group (Control) | 13 |
| Autoregulation Group | 6 |
Subject diagnosis of multisystem organ failure after surgery. (NCT00981474)
Timeframe: Up to 28 days after surgery.
| Intervention | Participants (Count of Participants) |
|---|---|
| Control | 7 |
| Intervention | 2 |
Subjects requiring new renal replacement therapy prior to discharge from hospital (NCT00981474)
Timeframe: Up to 28 days after surgery.
| Intervention | Participants (Count of Participants) |
|---|---|
| Control | 6 |
| Intervention | 4 |
Clinical diagnosis of postoperative atrial fibrillation from date of surgical procedure to discharge from the hospital. (NCT00981474)
Timeframe: Up to 28 days after surgery.
| Intervention | Participants (Count of Participants) |
|---|---|
| Control | 89 |
| Intervention | 79 |
Assessed with Confusion Assessment Method or Confusion Assessment Method-ICU along with adjudication by team of experts (NCT00981474)
Timeframe: Postoperative days 1-4
| Intervention | Participants (Count of Participants) |
|---|---|
| Usual Care Group (Control) | 34 |
| Autoregulation Group | 19 |
Clinical diagnosis of sepsis from time of surgical procedure to discharge from the hospital. (NCT00981474)
Timeframe: Up to 28 days after surgery.
| Intervention | Participants (Count of Participants) |
|---|---|
| Control | 7 |
| Intervention | 2 |
Duration of delirium will be analyzed, measured from 24 hours post-operation and daily until discharge. Additional measurements will be made at 1 month and 1 year after discharge. Delirium will be defined as an acute change in pre-operative baseline condition with additional features of inattention and either disorganized thinking and altered loss of consciousness, as defined by the Confusion Assessment Method (CAM). (NCT02546765)
Timeframe: Participants will be followed for the duration of the hospital stay, an average of 6 days, and at 1 month and 1- year following the date of surgery
| Intervention | days (Median) |
|---|---|
| Acetaminophen and Dexmedetomidine | 1 |
| Acetaminophen and Propofol | 1 |
| Placebo and Dexmedetomidine | 1 |
| Placebo and Propofol | 3 |
The follow up incidence of cognitive dysfunction will be analyzed at 1 month after discharge. T-MoCA is Telephone Montreal Cognitive Assessment Scale (MOCA). The T-MoCA is scored out of 22. The minimum score is 0 (worst) and maximum score is 22 (best). T-MOCA is converted back to 30 (full MOCA) with the help of conversion algorithms to a full MOCA.Example: 19/22 converts back to 30 by performing the following equation: (19×30) ÷ 22. The total converted score is 25.9 or 26/30 which is considered in the normal range. (NCT02546765)
Timeframe: Patients will be assessed for cognitive dysfunction with T-MOCA at 1 month following the date of surgery
| Intervention | units on a scale (Median) |
|---|---|
| Acetaminophen and Dexmedetomidine | 17 |
| Acetaminophen and Propofol | 18 |
| Placebo and Dexmedetomidine | 19 |
| Placebo and Propofol | 18 |
Defined by the number of days admitted in the hospital following the completion of surgery. (NCT02546765)
Timeframe: Measured in days admitted in the hospital, an average of 6 days
| Intervention | days (Median) |
|---|---|
| Acetaminophen and Dexmedetomidine | 8 |
| Acetaminophen and Propofol | 8 |
| Placebo and Dexmedetomidine | 9 |
| Placebo and Propofol | 8 |
Defined by the number of days admitted in the ICU prior to transfer to the general cardiac surgical floor (NCT02546765)
Timeframe: Measured in days admitted in the ICU, an average of 2 days
| Intervention | hours (Median) |
|---|---|
| Acetaminophen and Dexmedetomidine | 28.8 |
| Acetaminophen and Propofol | 30.3 |
| Placebo and Dexmedetomidine | 49.1 |
| Placebo and Propofol | 29.3 |
Incidence of delirium will be analyzed between patients treated with and without IV acetaminophen, measured from 24 hours post-operation and daily until discharge. Delirium will be defined as an acute change in pre-operative baseline condition with additional features of inattention and either disorganized thinking and altered loss of consciousness, as defined by the Confusion Assessment Method (CAM). (NCT02546765)
Timeframe: Participants will be followed for the duration of the hospital stay, an average of 5 days
| Intervention | Participants (Count of Participants) |
|---|---|
| Acetaminophen and Dexmedetomidine | 2 |
| Acetaminophen and Propofol | 4 |
| Placebo and Dexmedetomidine | 8 |
| Placebo and Propofol | 9 |
MoCA scores at discharge will be reported in order to assess the occurrence of postoperative cognitive decline. Blinded study staff trained in administering the assessments will collect the data. MoCA is scored on a scale from 0 [worst] to 30 [best]; ǂA MoCA score of 24 would be equivalent to an Mini-Mental State Examination (MMSE) of about 27 or 28. Depending on education and peak intellectual attainment, such a score could be consistent with being either cognitively normal, or having very early mild cognitive impairment. Certainly such a person would be capable of living independently in the community and managing most or all of their affairs. (NCT02546765)
Timeframe: On the day of discharge, an average of 6 days
| Intervention | score on a scale (Median) |
|---|---|
| Acetaminophen and Dexmedetomidine | 23 |
| Acetaminophen and Propofol | 24 |
| Placebo and Dexmedetomidine | 24 |
| Placebo and Propofol | 23 |
Defined by the amount of additional opioid (IV morphine or hydromorphone) and oral acetaminophen medications required in the first 48 hours postoperatively. Values will be converted to morphine equivalents for analysis. Total morphine equivalent is calculated as the sum of (fentanyl dose x 100)+(hydromorphone dose x 4)+morphine dose+(oxycodone dose x 1.5) (NCT02546765)
Timeframe: Participants will be followed for the first 48 hours postoperatively.
| Intervention | mcg (Median) |
|---|---|
| Acetaminophen and Dexmedetomidine | 10050 |
| Acetaminophen and Propofol | 12611 |
| Placebo and Dexmedetomidine | 11382 |
| Placebo and Propofol | 12616 |
Severity of delirium will be analyzed, measured from 24 hours post-operation and daily until discharge. The worst severity experienced while in the hospital will be analyzed. Delirium will be defined as an acute change in pre-operative baseline condition with additional features of inattention and either disorganized thinking and altered loss of consciousness, as defined by the Confusion Assessment Method Severity Score (CAM-S, Confusion Assessment Method-Severity). range 0 [best/no delirium] to 19 [worst]; Minimal Clinical Important Difference (MCID) 2 points (NCT02546765)
Timeframe: Participants will be followed for the duration of the hospital stay, an average of 6 days
| Intervention | units on a scale (Median) |
|---|---|
| Acetaminophen and Dexmedetomidine | 10 |
| Acetaminophen and Propofol | 8 |
| Placebo and Dexmedetomidine | 6 |
| Placebo and Propofol | 9 |
Days utilizing restraints is defined as the number of days restraints were applied because of delirium in the first 14 days of hospitalization. (NCT02654314)
Timeframe: length of hospitalization, not to exceed 14 days
| Intervention | days (Median) |
|---|---|
| Melatonin | 0 |
| Cellulose Microcrystylline | 0 |
Delirium is defined by the Short Form Confusion Assessment Method (CAM). There must be inattention and either an acute or fluctuating course plus either disorganized thinking or an altered level of consciousness to be diagnosed with delirium. Presented is a count of individuals with reported delirium during hospitalization. (NCT02654314)
Timeframe: length of hospitalization, not to exceed 14 days
| Intervention | Participants (Count of Participants) |
|---|---|
| Melatonin | 2 |
| Cellulose Microcrystylline | 8 |
Length of stay is defined as the total time hospitalized for the acute illness (in days). (NCT02654314)
Timeframe: from day of admission to completion of acute care, not to exceed 30 days
| Intervention | days (Mean) |
|---|---|
| Melatonin | 4.58 |
| Cellulose Microcrystylline | 4.71 |
Number of delirium anti-psychotic drug doses given for symptoms of delirium. Presented are the number of doses per days of hospitalization. (NCT02654314)
Timeframe: length of hospitalization, not to exceed 14 days
| Intervention | number of doses per days of hospitalizat (Median) |
|---|---|
| Melatonin | 0 |
| Cellulose Microcrystylline | 0 |
Measure of facial swelling will be performed using 3-dimensional photogrammetry. The 3d photo acquisition is non-invasive without radiation concern. The images will be taken before and after surgery to measure and compare the degree of facial swelling. Side effects from the steroid use are expected to be low under normal clinical dosage, but will also be monitored. Symptoms of wound infection, psychosis, and prolonged wound healing will be studied. There should be no long term complication, since the steroid use is one single dose. (NCT01431014)
Timeframe: 1 year
| Intervention | ml (Mean) | ||
|---|---|---|---|
| 36 hours postoperatively | 1week postoperatively | 1month postoperatively | |
| "DexamethasoneHigh-dose" | 167.06 | 61.39 | 29.85 |
| "DexamethasoneLow-dose" | 190.73 | 57.62 | 19.34 |
16 reviews available for lorazepam and Delirium
| Article | Year |
|---|---|
Drug therapy for delirium in terminally ill adults.
Topics: Adult; Antipsychotic Agents; Chlorpromazine; Delirium; Haloperidol; Humans; Lorazepam; Randomized Co | 2020 |
Benzodiazepines for treatment of patients with delirium excluding those who are cared for in an intensive care unit.
Topics: Antipsychotic Agents; Benzodiazepines; Critical Care; Delirium; Haloperidol; Humans; Lorazepam; Pall | 2020 |
Association of Delirium Response and Safety of Pharmacological Interventions for the Management and Prevention of Delirium: A Network Meta-analysis.
Topics: Antipsychotic Agents; Delirium; Drug Therapy, Combination; Haloperidol; Humans; Indenes; Lorazepam; | 2019 |
[Pharmacological treatment of delirium in palliative care patients. A systematic literature review].
Topics: Antipsychotic Agents; Aripiprazole; Benzodiazepines; Clinical Trials as Topic; Delirium; Evidence-Ba | 2013 |
[Venlafaxine-induced delirium mediated by high doses].
Topics: Aged; Antidepressive Agents; Comorbidity; Confusion; Delirium; Depressive Disorder, Major; Dopamine; | 2015 |
Benzodiazepines for delirium.
Topics: Benzodiazepines; Delirium; Dexmedetomidine; Humans; Lorazepam | 2009 |
Benzodiazepines for delirium.
Topics: Benzodiazepines; Delirium; Dexmedetomidine; Humans; Lorazepam | 2009 |
Delirium and sedation in the ICU.
Topics: Conscious Sedation; Delirium; Dexmedetomidine; Diagnosis, Differential; Hospital Mortality; Humans; | 2011 |
Brain dysfunction in patients with chronic critical illness.
Topics: Antipsychotic Agents; Attention Deficit Disorder with Hyperactivity; Chronic Disease; Coma; Comorbid | 2012 |
Drug therapy for delirium in terminally ill adult patients.
Topics: Adult; Antipsychotic Agents; Chlorpromazine; Delirium; Haloperidol; Humans; Lorazepam; Randomized Co | 2012 |
Delirious mania: detection, diagnosis, and clinical management in the acute setting.
Topics: Bipolar Disorder; Catatonia; Delirium; Electroconvulsive Therapy; Humans; Hypnotics and Sedatives; L | 2013 |
Drug therapy for delirium in terminally ill patients.
Topics: Antipsychotic Agents; Chlorpromazine; Delirium; Haloperidol; Humans; Lorazepam; Terminally Ill | 2004 |
Delirium in older persons.
Topics: Aged; Anti-Anxiety Agents; Antipsychotic Agents; Delirium; Dementia; Diagnosis, Differential; Humans | 2006 |
Delirium in older persons.
Topics: Aged; Anti-Anxiety Agents; Antipsychotic Agents; Delirium; Dementia; Diagnosis, Differential; Humans | 2006 |
Delirium in older persons.
Topics: Aged; Anti-Anxiety Agents; Antipsychotic Agents; Delirium; Dementia; Diagnosis, Differential; Humans | 2006 |
Delirium in older persons.
Topics: Aged; Anti-Anxiety Agents; Antipsychotic Agents; Delirium; Dementia; Diagnosis, Differential; Humans | 2006 |
Delirium in older persons.
Topics: Aged; Anti-Anxiety Agents; Antipsychotic Agents; Delirium; Dementia; Diagnosis, Differential; Humans | 2006 |
Delirium in older persons.
Topics: Aged; Anti-Anxiety Agents; Antipsychotic Agents; Delirium; Dementia; Diagnosis, Differential; Humans | 2006 |
Delirium in older persons.
Topics: Aged; Anti-Anxiety Agents; Antipsychotic Agents; Delirium; Dementia; Diagnosis, Differential; Humans | 2006 |
Delirium in older persons.
Topics: Aged; Anti-Anxiety Agents; Antipsychotic Agents; Delirium; Dementia; Diagnosis, Differential; Humans | 2006 |
Delirium in older persons.
Topics: Aged; Anti-Anxiety Agents; Antipsychotic Agents; Delirium; Dementia; Diagnosis, Differential; Humans | 2006 |
Delirium in older persons.
Topics: Aged; Anti-Anxiety Agents; Antipsychotic Agents; Delirium; Dementia; Diagnosis, Differential; Humans | 2006 |
Delirium in older persons.
Topics: Aged; Anti-Anxiety Agents; Antipsychotic Agents; Delirium; Dementia; Diagnosis, Differential; Humans | 2006 |
Delirium in older persons.
Topics: Aged; Anti-Anxiety Agents; Antipsychotic Agents; Delirium; Dementia; Diagnosis, Differential; Humans | 2006 |
Delirium in older persons.
Topics: Aged; Anti-Anxiety Agents; Antipsychotic Agents; Delirium; Dementia; Diagnosis, Differential; Humans | 2006 |
Delirium in older persons.
Topics: Aged; Anti-Anxiety Agents; Antipsychotic Agents; Delirium; Dementia; Diagnosis, Differential; Humans | 2006 |
Delirium in older persons.
Topics: Aged; Anti-Anxiety Agents; Antipsychotic Agents; Delirium; Dementia; Diagnosis, Differential; Humans | 2006 |
Delirium in older persons.
Topics: Aged; Anti-Anxiety Agents; Antipsychotic Agents; Delirium; Dementia; Diagnosis, Differential; Humans | 2006 |
Delirium in older persons.
Topics: Aged; Anti-Anxiety Agents; Antipsychotic Agents; Delirium; Dementia; Diagnosis, Differential; Humans | 2006 |
Delirium in older persons.
Topics: Aged; Anti-Anxiety Agents; Antipsychotic Agents; Delirium; Dementia; Diagnosis, Differential; Humans | 2006 |
Delirium in older persons.
Topics: Aged; Anti-Anxiety Agents; Antipsychotic Agents; Delirium; Dementia; Diagnosis, Differential; Humans | 2006 |
Delirium in older persons.
Topics: Aged; Anti-Anxiety Agents; Antipsychotic Agents; Delirium; Dementia; Diagnosis, Differential; Humans | 2006 |
Delirium in older persons.
Topics: Aged; Anti-Anxiety Agents; Antipsychotic Agents; Delirium; Dementia; Diagnosis, Differential; Humans | 2006 |
Delirium in older persons.
Topics: Aged; Anti-Anxiety Agents; Antipsychotic Agents; Delirium; Dementia; Diagnosis, Differential; Humans | 2006 |
Delirium in older persons.
Topics: Aged; Anti-Anxiety Agents; Antipsychotic Agents; Delirium; Dementia; Diagnosis, Differential; Humans | 2006 |
Delirium in older persons.
Topics: Aged; Anti-Anxiety Agents; Antipsychotic Agents; Delirium; Dementia; Diagnosis, Differential; Humans | 2006 |
Delirium in older persons.
Topics: Aged; Anti-Anxiety Agents; Antipsychotic Agents; Delirium; Dementia; Diagnosis, Differential; Humans | 2006 |
Delirium in older persons.
Topics: Aged; Anti-Anxiety Agents; Antipsychotic Agents; Delirium; Dementia; Diagnosis, Differential; Humans | 2006 |
Delirium in older persons.
Topics: Aged; Anti-Anxiety Agents; Antipsychotic Agents; Delirium; Dementia; Diagnosis, Differential; Humans | 2006 |
Delirium in older persons.
Topics: Aged; Anti-Anxiety Agents; Antipsychotic Agents; Delirium; Dementia; Diagnosis, Differential; Humans | 2006 |
Delirium in older persons.
Topics: Aged; Anti-Anxiety Agents; Antipsychotic Agents; Delirium; Dementia; Diagnosis, Differential; Humans | 2006 |
Delirium in older persons.
Topics: Aged; Anti-Anxiety Agents; Antipsychotic Agents; Delirium; Dementia; Diagnosis, Differential; Humans | 2006 |
Delirium in older persons.
Topics: Aged; Anti-Anxiety Agents; Antipsychotic Agents; Delirium; Dementia; Diagnosis, Differential; Humans | 2006 |
Delirium in older persons.
Topics: Aged; Anti-Anxiety Agents; Antipsychotic Agents; Delirium; Dementia; Diagnosis, Differential; Humans | 2006 |
Delirium in older persons.
Topics: Aged; Anti-Anxiety Agents; Antipsychotic Agents; Delirium; Dementia; Diagnosis, Differential; Humans | 2006 |
Delirium in older persons.
Topics: Aged; Anti-Anxiety Agents; Antipsychotic Agents; Delirium; Dementia; Diagnosis, Differential; Humans | 2006 |
Delirium in older persons.
Topics: Aged; Anti-Anxiety Agents; Antipsychotic Agents; Delirium; Dementia; Diagnosis, Differential; Humans | 2006 |
Delirium in older persons.
Topics: Aged; Anti-Anxiety Agents; Antipsychotic Agents; Delirium; Dementia; Diagnosis, Differential; Humans | 2006 |
Delirium in older persons.
Topics: Aged; Anti-Anxiety Agents; Antipsychotic Agents; Delirium; Dementia; Diagnosis, Differential; Humans | 2006 |
Delirium in older persons.
Topics: Aged; Anti-Anxiety Agents; Antipsychotic Agents; Delirium; Dementia; Diagnosis, Differential; Humans | 2006 |
Delirium in older persons.
Topics: Aged; Anti-Anxiety Agents; Antipsychotic Agents; Delirium; Dementia; Diagnosis, Differential; Humans | 2006 |
Delirium in older persons.
Topics: Aged; Anti-Anxiety Agents; Antipsychotic Agents; Delirium; Dementia; Diagnosis, Differential; Humans | 2006 |
Delirium in older persons.
Topics: Aged; Anti-Anxiety Agents; Antipsychotic Agents; Delirium; Dementia; Diagnosis, Differential; Humans | 2006 |
Delirium in older persons.
Topics: Aged; Anti-Anxiety Agents; Antipsychotic Agents; Delirium; Dementia; Diagnosis, Differential; Humans | 2006 |
Delirium in older persons.
Topics: Aged; Anti-Anxiety Agents; Antipsychotic Agents; Delirium; Dementia; Diagnosis, Differential; Humans | 2006 |
Delirium in older persons.
Topics: Aged; Anti-Anxiety Agents; Antipsychotic Agents; Delirium; Dementia; Diagnosis, Differential; Humans | 2006 |
Delirium in older persons.
Topics: Aged; Anti-Anxiety Agents; Antipsychotic Agents; Delirium; Dementia; Diagnosis, Differential; Humans | 2006 |
Delirium in older persons.
Topics: Aged; Anti-Anxiety Agents; Antipsychotic Agents; Delirium; Dementia; Diagnosis, Differential; Humans | 2006 |
Delirium in older persons.
Topics: Aged; Anti-Anxiety Agents; Antipsychotic Agents; Delirium; Dementia; Diagnosis, Differential; Humans | 2006 |
Delirium in older persons.
Topics: Aged; Anti-Anxiety Agents; Antipsychotic Agents; Delirium; Dementia; Diagnosis, Differential; Humans | 2006 |
Delirium in older persons.
Topics: Aged; Anti-Anxiety Agents; Antipsychotic Agents; Delirium; Dementia; Diagnosis, Differential; Humans | 2006 |
Delirium in older persons.
Topics: Aged; Anti-Anxiety Agents; Antipsychotic Agents; Delirium; Dementia; Diagnosis, Differential; Humans | 2006 |
Delirium in older persons.
Topics: Aged; Anti-Anxiety Agents; Antipsychotic Agents; Delirium; Dementia; Diagnosis, Differential; Humans | 2006 |
Delirium in older persons.
Topics: Aged; Anti-Anxiety Agents; Antipsychotic Agents; Delirium; Dementia; Diagnosis, Differential; Humans | 2006 |
Delirium in older persons.
Topics: Aged; Anti-Anxiety Agents; Antipsychotic Agents; Delirium; Dementia; Diagnosis, Differential; Humans | 2006 |
Delirium in older persons.
Topics: Aged; Anti-Anxiety Agents; Antipsychotic Agents; Delirium; Dementia; Diagnosis, Differential; Humans | 2006 |
Delirium in older persons.
Topics: Aged; Anti-Anxiety Agents; Antipsychotic Agents; Delirium; Dementia; Diagnosis, Differential; Humans | 2006 |
Delirium in older persons.
Topics: Aged; Anti-Anxiety Agents; Antipsychotic Agents; Delirium; Dementia; Diagnosis, Differential; Humans | 2006 |
Delirium in older persons.
Topics: Aged; Anti-Anxiety Agents; Antipsychotic Agents; Delirium; Dementia; Diagnosis, Differential; Humans | 2006 |
Delirium in older persons.
Topics: Aged; Anti-Anxiety Agents; Antipsychotic Agents; Delirium; Dementia; Diagnosis, Differential; Humans | 2006 |
Delirium in older persons.
Topics: Aged; Anti-Anxiety Agents; Antipsychotic Agents; Delirium; Dementia; Diagnosis, Differential; Humans | 2006 |
Delirium in older persons.
Topics: Aged; Anti-Anxiety Agents; Antipsychotic Agents; Delirium; Dementia; Diagnosis, Differential; Humans | 2006 |
Delirium in older persons.
Topics: Aged; Anti-Anxiety Agents; Antipsychotic Agents; Delirium; Dementia; Diagnosis, Differential; Humans | 2006 |
Delirium in older persons.
Topics: Aged; Anti-Anxiety Agents; Antipsychotic Agents; Delirium; Dementia; Diagnosis, Differential; Humans | 2006 |
Delirium in older persons.
Topics: Aged; Anti-Anxiety Agents; Antipsychotic Agents; Delirium; Dementia; Diagnosis, Differential; Humans | 2006 |
Delirium in older persons.
Topics: Aged; Anti-Anxiety Agents; Antipsychotic Agents; Delirium; Dementia; Diagnosis, Differential; Humans | 2006 |
Delirium in older persons.
Topics: Aged; Anti-Anxiety Agents; Antipsychotic Agents; Delirium; Dementia; Diagnosis, Differential; Humans | 2006 |
Delirium in older persons.
Topics: Aged; Anti-Anxiety Agents; Antipsychotic Agents; Delirium; Dementia; Diagnosis, Differential; Humans | 2006 |
Delirium in older persons.
Topics: Aged; Anti-Anxiety Agents; Antipsychotic Agents; Delirium; Dementia; Diagnosis, Differential; Humans | 2006 |
Delirium in older persons.
Topics: Aged; Anti-Anxiety Agents; Antipsychotic Agents; Delirium; Dementia; Diagnosis, Differential; Humans | 2006 |
Delirium in older persons.
Topics: Aged; Anti-Anxiety Agents; Antipsychotic Agents; Delirium; Dementia; Diagnosis, Differential; Humans | 2006 |
Delirium in older persons.
Topics: Aged; Anti-Anxiety Agents; Antipsychotic Agents; Delirium; Dementia; Diagnosis, Differential; Humans | 2006 |
Delirium in older persons.
Topics: Aged; Anti-Anxiety Agents; Antipsychotic Agents; Delirium; Dementia; Diagnosis, Differential; Humans | 2006 |
Delirium in older persons.
Topics: Aged; Anti-Anxiety Agents; Antipsychotic Agents; Delirium; Dementia; Diagnosis, Differential; Humans | 2006 |
Delirium in older persons.
Topics: Aged; Anti-Anxiety Agents; Antipsychotic Agents; Delirium; Dementia; Diagnosis, Differential; Humans | 2006 |
Delirium in older persons.
Topics: Aged; Anti-Anxiety Agents; Antipsychotic Agents; Delirium; Dementia; Diagnosis, Differential; Humans | 2006 |
Delirium in older persons.
Topics: Aged; Anti-Anxiety Agents; Antipsychotic Agents; Delirium; Dementia; Diagnosis, Differential; Humans | 2006 |
Delirium in older persons.
Topics: Aged; Anti-Anxiety Agents; Antipsychotic Agents; Delirium; Dementia; Diagnosis, Differential; Humans | 2006 |
Delirium in older persons.
Topics: Aged; Anti-Anxiety Agents; Antipsychotic Agents; Delirium; Dementia; Diagnosis, Differential; Humans | 2006 |
Delirium in older persons.
Topics: Aged; Anti-Anxiety Agents; Antipsychotic Agents; Delirium; Dementia; Diagnosis, Differential; Humans | 2006 |
Delirium in older persons.
Topics: Aged; Anti-Anxiety Agents; Antipsychotic Agents; Delirium; Dementia; Diagnosis, Differential; Humans | 2006 |
Delirium in older persons.
Topics: Aged; Anti-Anxiety Agents; Antipsychotic Agents; Delirium; Dementia; Diagnosis, Differential; Humans | 2006 |
Delirium in older persons.
Topics: Aged; Anti-Anxiety Agents; Antipsychotic Agents; Delirium; Dementia; Diagnosis, Differential; Humans | 2006 |
Delirium in older persons.
Topics: Aged; Anti-Anxiety Agents; Antipsychotic Agents; Delirium; Dementia; Diagnosis, Differential; Humans | 2006 |
Delirium in older persons.
Topics: Aged; Anti-Anxiety Agents; Antipsychotic Agents; Delirium; Dementia; Diagnosis, Differential; Humans | 2006 |
Delirium in older persons.
Topics: Aged; Anti-Anxiety Agents; Antipsychotic Agents; Delirium; Dementia; Diagnosis, Differential; Humans | 2006 |
Delirium in older persons.
Topics: Aged; Anti-Anxiety Agents; Antipsychotic Agents; Delirium; Dementia; Diagnosis, Differential; Humans | 2006 |
Delirium in older persons.
Topics: Aged; Anti-Anxiety Agents; Antipsychotic Agents; Delirium; Dementia; Diagnosis, Differential; Humans | 2006 |
Delirium in older persons.
Topics: Aged; Anti-Anxiety Agents; Antipsychotic Agents; Delirium; Dementia; Diagnosis, Differential; Humans | 2006 |
Delirium in older persons.
Topics: Aged; Anti-Anxiety Agents; Antipsychotic Agents; Delirium; Dementia; Diagnosis, Differential; Humans | 2006 |
Delirium in older persons.
Topics: Aged; Anti-Anxiety Agents; Antipsychotic Agents; Delirium; Dementia; Diagnosis, Differential; Humans | 2006 |
Delirium in older persons.
Topics: Aged; Anti-Anxiety Agents; Antipsychotic Agents; Delirium; Dementia; Diagnosis, Differential; Humans | 2006 |
Delirium in older persons.
Topics: Aged; Anti-Anxiety Agents; Antipsychotic Agents; Delirium; Dementia; Diagnosis, Differential; Humans | 2006 |
Delirium in older persons.
Topics: Aged; Anti-Anxiety Agents; Antipsychotic Agents; Delirium; Dementia; Diagnosis, Differential; Humans | 2006 |
Delirium in older persons.
Topics: Aged; Anti-Anxiety Agents; Antipsychotic Agents; Delirium; Dementia; Diagnosis, Differential; Humans | 2006 |
Delirium in older persons.
Topics: Aged; Anti-Anxiety Agents; Antipsychotic Agents; Delirium; Dementia; Diagnosis, Differential; Humans | 2006 |
Delirium in older persons.
Topics: Aged; Anti-Anxiety Agents; Antipsychotic Agents; Delirium; Dementia; Diagnosis, Differential; Humans | 2006 |
Delirium in older persons.
Topics: Aged; Anti-Anxiety Agents; Antipsychotic Agents; Delirium; Dementia; Diagnosis, Differential; Humans | 2006 |
Delirium in older persons.
Topics: Aged; Anti-Anxiety Agents; Antipsychotic Agents; Delirium; Dementia; Diagnosis, Differential; Humans | 2006 |
Delirium in older persons.
Topics: Aged; Anti-Anxiety Agents; Antipsychotic Agents; Delirium; Dementia; Diagnosis, Differential; Humans | 2006 |
Delirium in older persons.
Topics: Aged; Anti-Anxiety Agents; Antipsychotic Agents; Delirium; Dementia; Diagnosis, Differential; Humans | 2006 |
Delirium in older persons.
Topics: Aged; Anti-Anxiety Agents; Antipsychotic Agents; Delirium; Dementia; Diagnosis, Differential; Humans | 2006 |
Delirium in older persons.
Topics: Aged; Anti-Anxiety Agents; Antipsychotic Agents; Delirium; Dementia; Diagnosis, Differential; Humans | 2006 |
Delirium in older persons.
Topics: Aged; Anti-Anxiety Agents; Antipsychotic Agents; Delirium; Dementia; Diagnosis, Differential; Humans | 2006 |
Delirium in older persons.
Topics: Aged; Anti-Anxiety Agents; Antipsychotic Agents; Delirium; Dementia; Diagnosis, Differential; Humans | 2006 |
Delirium in older persons.
Topics: Aged; Anti-Anxiety Agents; Antipsychotic Agents; Delirium; Dementia; Diagnosis, Differential; Humans | 2006 |
Delirium in older persons.
Topics: Aged; Anti-Anxiety Agents; Antipsychotic Agents; Delirium; Dementia; Diagnosis, Differential; Humans | 2006 |
Delirium in older persons.
Topics: Aged; Anti-Anxiety Agents; Antipsychotic Agents; Delirium; Dementia; Diagnosis, Differential; Humans | 2006 |
Delirium in older persons.
Topics: Aged; Anti-Anxiety Agents; Antipsychotic Agents; Delirium; Dementia; Diagnosis, Differential; Humans | 2006 |
Delirium in older persons.
Topics: Aged; Anti-Anxiety Agents; Antipsychotic Agents; Delirium; Dementia; Diagnosis, Differential; Humans | 2006 |
Delirium in older persons.
Topics: Aged; Anti-Anxiety Agents; Antipsychotic Agents; Delirium; Dementia; Diagnosis, Differential; Humans | 2006 |
Delirium in older persons.
Topics: Aged; Anti-Anxiety Agents; Antipsychotic Agents; Delirium; Dementia; Diagnosis, Differential; Humans | 2006 |
Delirium in older persons.
Topics: Aged; Anti-Anxiety Agents; Antipsychotic Agents; Delirium; Dementia; Diagnosis, Differential; Humans | 2006 |
Delirium in older persons.
Topics: Aged; Anti-Anxiety Agents; Antipsychotic Agents; Delirium; Dementia; Diagnosis, Differential; Humans | 2006 |
Delirium in older persons.
Topics: Aged; Anti-Anxiety Agents; Antipsychotic Agents; Delirium; Dementia; Diagnosis, Differential; Humans | 2006 |
Delirium in older persons.
Topics: Aged; Anti-Anxiety Agents; Antipsychotic Agents; Delirium; Dementia; Diagnosis, Differential; Humans | 2006 |
Delirium in older persons.
Topics: Aged; Anti-Anxiety Agents; Antipsychotic Agents; Delirium; Dementia; Diagnosis, Differential; Humans | 2006 |
Delirium in older persons.
Topics: Aged; Anti-Anxiety Agents; Antipsychotic Agents; Delirium; Dementia; Diagnosis, Differential; Humans | 2006 |
Delirium in older persons.
Topics: Aged; Anti-Anxiety Agents; Antipsychotic Agents; Delirium; Dementia; Diagnosis, Differential; Humans | 2006 |
Delirium in older persons.
Topics: Aged; Anti-Anxiety Agents; Antipsychotic Agents; Delirium; Dementia; Diagnosis, Differential; Humans | 2006 |
Delirium in older persons.
Topics: Aged; Anti-Anxiety Agents; Antipsychotic Agents; Delirium; Dementia; Diagnosis, Differential; Humans | 2006 |
Delirium in older persons.
Topics: Aged; Anti-Anxiety Agents; Antipsychotic Agents; Delirium; Dementia; Diagnosis, Differential; Humans | 2006 |
Delirium in older persons.
Topics: Aged; Anti-Anxiety Agents; Antipsychotic Agents; Delirium; Dementia; Diagnosis, Differential; Humans | 2006 |
Delirium and cognitive dysfunction in the intensive care unit.
Topics: Aged; Analgesics; Cognition Disorders; Delirium; Humans; Hypnotics and Sedatives; Intensive Care Uni | 2006 |
Delirium in cancer patients.
Topics: Aged; Delirium; Diagnosis, Differential; Haloperidol; Humans; Lorazepam; Neoplasms; Neuropsychologic | 1991 |
Management of delirium in terminally ill AIDS patients.
Topics: Acquired Immunodeficiency Syndrome; Delirium; Haloperidol; Humans; Injections, Intravenous; Lorazepa | 1989 |
9 trials available for lorazepam and Delirium
| Article | Year |
|---|---|
A randomized trial comparing physostigmine vs lorazepam for treatment of antimuscarinic (anticholinergic) toxidrome.
Topics: Adolescent; Akathisia, Drug-Induced; Anti-Anxiety Agents; Delirium; Diphenhydramine; Double-Blind Me | 2021 |
Association among rescue neuroleptic use, agitation, and perceived comfort: secondary analysis of a randomized clinical trial on agitated delirium.
Topics: Antipsychotic Agents; Delirium; Double-Blind Method; Haloperidol; Humans; Lorazepam; Psychomotor Agi | 2021 |
Effect of Lorazepam With Haloperidol vs Haloperidol Alone on Agitated Delirium in Patients With Advanced Cancer Receiving Palliative Care: A Randomized Clinical Trial.
Topics: Adult; Aged; Aged, 80 and over; Anti-Anxiety Agents; Antipsychotic Agents; Delirium; Double-Blind Me | 2017 |
Effect of Lorazepam With Haloperidol vs Haloperidol Alone on Agitated Delirium in Patients With Advanced Cancer Receiving Palliative Care: A Randomized Clinical Trial.
Topics: Adult; Aged; Aged, 80 and over; Anti-Anxiety Agents; Antipsychotic Agents; Delirium; Double-Blind Me | 2017 |
Effect of Lorazepam With Haloperidol vs Haloperidol Alone on Agitated Delirium in Patients With Advanced Cancer Receiving Palliative Care: A Randomized Clinical Trial.
Topics: Adult; Aged; Aged, 80 and over; Anti-Anxiety Agents; Antipsychotic Agents; Delirium; Double-Blind Me | 2017 |
Effect of Lorazepam With Haloperidol vs Haloperidol Alone on Agitated Delirium in Patients With Advanced Cancer Receiving Palliative Care: A Randomized Clinical Trial.
Topics: Adult; Aged; Aged, 80 and over; Anti-Anxiety Agents; Antipsychotic Agents; Delirium; Double-Blind Me | 2017 |
Sedative Plasma Concentrations and Delirium Risk in Critical Illness.
Topics: Aged; Critical Illness; Delirium; Dexmedetomidine; Female; Humans; Hypnotics and Sedatives; Intensiv | 2018 |
The minimal clinically important difference of the Richmond Agitation-Sedation Scale in patients with cancer with agitated delirium.
Topics: Adult; Aged; Aged, 80 and over; Delirium; Drug Therapy, Combination; Female; Haloperidol; Humans; Lo | 2018 |
Lorazepam Added to Haloperidol Effective for Agitated Delirium in End-of-Life Cancer Patients.
Topics: Adult; Aged; Aged, 80 and over; Antipsychotic Agents; Delirium; Drug Therapy, Combination; Female; H | 2018 |
Effect of dexmedetomidine versus lorazepam on outcome in patients with sepsis: an a priori-designed analysis of the MENDS randomized controlled trial.
Topics: Adult; Aged; Coma; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypnotics and Sed | 2010 |
Effect of dexmedetomidine versus lorazepam on outcome in patients with sepsis: an a priori-designed analysis of the MENDS randomized controlled trial.
Topics: Adult; Aged; Coma; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypnotics and Sed | 2010 |
Effect of dexmedetomidine versus lorazepam on outcome in patients with sepsis: an a priori-designed analysis of the MENDS randomized controlled trial.
Topics: Adult; Aged; Coma; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypnotics and Sed | 2010 |
Effect of dexmedetomidine versus lorazepam on outcome in patients with sepsis: an a priori-designed analysis of the MENDS randomized controlled trial.
Topics: Adult; Aged; Coma; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypnotics and Sed | 2010 |
Effect of dexmedetomidine versus lorazepam on outcome in patients with sepsis: an a priori-designed analysis of the MENDS randomized controlled trial.
Topics: Adult; Aged; Coma; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypnotics and Sed | 2010 |
Effect of dexmedetomidine versus lorazepam on outcome in patients with sepsis: an a priori-designed analysis of the MENDS randomized controlled trial.
Topics: Adult; Aged; Coma; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypnotics and Sed | 2010 |
Effect of dexmedetomidine versus lorazepam on outcome in patients with sepsis: an a priori-designed analysis of the MENDS randomized controlled trial.
Topics: Adult; Aged; Coma; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypnotics and Sed | 2010 |
Effect of dexmedetomidine versus lorazepam on outcome in patients with sepsis: an a priori-designed analysis of the MENDS randomized controlled trial.
Topics: Adult; Aged; Coma; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypnotics and Sed | 2010 |
Effect of dexmedetomidine versus lorazepam on outcome in patients with sepsis: an a priori-designed analysis of the MENDS randomized controlled trial.
Topics: Adult; Aged; Coma; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypnotics and Sed | 2010 |
Effect of dexmedetomidine versus lorazepam on outcome in patients with sepsis: an a priori-designed analysis of the MENDS randomized controlled trial.
Topics: Adult; Aged; Coma; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypnotics and Sed | 2010 |
Effect of dexmedetomidine versus lorazepam on outcome in patients with sepsis: an a priori-designed analysis of the MENDS randomized controlled trial.
Topics: Adult; Aged; Coma; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypnotics and Sed | 2010 |
Effect of dexmedetomidine versus lorazepam on outcome in patients with sepsis: an a priori-designed analysis of the MENDS randomized controlled trial.
Topics: Adult; Aged; Coma; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypnotics and Sed | 2010 |
Effect of dexmedetomidine versus lorazepam on outcome in patients with sepsis: an a priori-designed analysis of the MENDS randomized controlled trial.
Topics: Adult; Aged; Coma; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypnotics and Sed | 2010 |
Effect of dexmedetomidine versus lorazepam on outcome in patients with sepsis: an a priori-designed analysis of the MENDS randomized controlled trial.
Topics: Adult; Aged; Coma; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypnotics and Sed | 2010 |
Effect of dexmedetomidine versus lorazepam on outcome in patients with sepsis: an a priori-designed analysis of the MENDS randomized controlled trial.
Topics: Adult; Aged; Coma; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypnotics and Sed | 2010 |
Effect of dexmedetomidine versus lorazepam on outcome in patients with sepsis: an a priori-designed analysis of the MENDS randomized controlled trial.
Topics: Adult; Aged; Coma; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypnotics and Sed | 2010 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
A double-blind trial of haloperidol, chlorpromazine, and lorazepam in the treatment of delirium in hospitalized AIDS patients.
Topics: Adult; AIDS Dementia Complex; Basal Ganglia Diseases; Chlorpromazine; Delirium; Double-Blind Method; | 1996 |
35 other studies available for lorazepam and Delirium
| Article | Year |
|---|---|
Antipsychotics and Lorazepam During Delirium: Are We Harming Older Patients? A Real-Life Data Study.
Topics: Aftercare; Aged; Aged, 80 and over; Antipsychotic Agents; Delirium; Humans; Lorazepam; Patient Disch | 2021 |
A Case of Delirious Mania Induced by COVID-19 Treated With Electroconvulsive Therapy.
Topics: COVID-19; Delirium; Electroconvulsive Therapy; Humans; Lorazepam; Male; Mania; Mental Status and Dem | 2021 |
Two unusual cases of protracted inter-ictal delirium following electroconvulsive therapy.
Topics: Adult; Antipsychotic Agents; Delirium; Electroconvulsive Therapy; Haloperidol; Humans; Lorazepam; Ma | 2017 |
Haloperidol overdosing in the treatment of agitated hospitalized older people with delirium: a retrospective chart review from a community teaching hospital.
Topics: Aged; Aged, 80 and over; Aging; Anti-Anxiety Agents; Delirium; Dopamine Antagonists; Dose-Response R | 2013 |
Patterns of opiate, benzodiazepine, and antipsychotic drug dosing in older patients in a medical intensive care unit.
Topics: Aged; Analgesics, Opioid; Antipsychotic Agents; Bayes Theorem; Benzodiazepines; Cohort Studies; Conn | 2013 |
Look again at psychedelic drugs.
Topics: Anxiety; Delirium; Depression; Diazepam; Hallucinogens; Haloperidol; Humans; Lorazepam; Midazolam; P | 2016 |
Valproate for agitation in critically ill patients: A retrospective study.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Delirium; Dexmedetomidine; Female; Fentanyl; GABA | 2017 |
Suspected Delirium Predicts the Thoroughness of Catatonia Evaluation.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticonvulsants; Catatonia; Delirium; Electroconvulsive | 2017 |
The complex interplay between delirium, sepsis and sedation.
Topics: Brain; Critical Illness; Delirium; Dexmedetomidine; Humans; Hypnotics and Sedatives; Intensive Care | 2010 |
Electroconvulsive therapy in the treatment of delirious mania: a report of 2 patients.
Topics: Adolescent; Antimanic Agents; Bipolar Disorder; Catatonia; Delirium; Electroconvulsive Therapy; Fema | 2010 |
[Delirium induced by drug treatment].
Topics: Aged; Benzodiazepines; Brain; Cholinergic Antagonists; Delirium; Diagnosis, Differential; Diuretics; | 2011 |
Sleep in the ICU: where dreams go to die.
Topics: Delirium; Female; Humans; Hypnotics and Sedatives; Lorazepam; Male; Sleep Wake Disorders | 2011 |
Sleep disturbances in the critically ill patients: role of delirium and sedative agents.
Topics: Aged; Critical Illness; Delirium; Female; Humans; Hypnotics and Sedatives; Lorazepam; Male; Middle A | 2011 |
Sleep disturbances in the critically ill patients: role of delirium and sedative agents.
Topics: Aged; Critical Illness; Delirium; Female; Humans; Hypnotics and Sedatives; Lorazepam; Male; Middle A | 2011 |
Sleep disturbances in the critically ill patients: role of delirium and sedative agents.
Topics: Aged; Critical Illness; Delirium; Female; Humans; Hypnotics and Sedatives; Lorazepam; Male; Middle A | 2011 |
Sleep disturbances in the critically ill patients: role of delirium and sedative agents.
Topics: Aged; Critical Illness; Delirium; Female; Humans; Hypnotics and Sedatives; Lorazepam; Male; Middle A | 2011 |
Sleep disturbances in the critically ill patients: role of delirium and sedative agents.
Topics: Aged; Critical Illness; Delirium; Female; Humans; Hypnotics and Sedatives; Lorazepam; Male; Middle A | 2011 |
Sleep disturbances in the critically ill patients: role of delirium and sedative agents.
Topics: Aged; Critical Illness; Delirium; Female; Humans; Hypnotics and Sedatives; Lorazepam; Male; Middle A | 2011 |
Sleep disturbances in the critically ill patients: role of delirium and sedative agents.
Topics: Aged; Critical Illness; Delirium; Female; Humans; Hypnotics and Sedatives; Lorazepam; Male; Middle A | 2011 |
Sleep disturbances in the critically ill patients: role of delirium and sedative agents.
Topics: Aged; Critical Illness; Delirium; Female; Humans; Hypnotics and Sedatives; Lorazepam; Male; Middle A | 2011 |
Sleep disturbances in the critically ill patients: role of delirium and sedative agents.
Topics: Aged; Critical Illness; Delirium; Female; Humans; Hypnotics and Sedatives; Lorazepam; Male; Middle A | 2011 |
Unusual presentation of a patient with GBL withdrawal: a case report.
Topics: 4-Butyrolactone; Adult; Akathisia, Drug-Induced; Antipsychotic Agents; Chlorpromazine; Delirium; Hal | 2011 |
Reversible delirium in an advanced cancer patient.
Topics: Amines; Analgesics; Analgesics, Opioid; Bone Neoplasms; Breast Neoplasms; Carcinoma, Intraductal, No | 2012 |
[Delirium caused by nonconvulsive status epilepticus].
Topics: Affect; Aged; Anticonvulsants; Antipsychotic Agents; Brain Edema; Confusion; Delirium; Dibenzothiaze | 2012 |
Delayed onset and prolonged interictal delirium following electroconvulsive therapy.
Topics: Cholinesterase Inhibitors; Delirium; Depressive Disorder; Donepezil; Electroconvulsive Therapy; Foll | 2012 |
Flumazenil reversal of lorazepam-induced acute delirium.
Topics: Anti-Anxiety Agents; Antidotes; Delirium; Flumazenil; Humans; Lorazepam; Male; Middle Aged | 2003 |
Two cases of severe gamma-hydroxybutyrate withdrawal delirium on a psychiatric unit: recommendations for management.
Topics: Adult; Anticonvulsants; Antihypertensive Agents; Clonazepam; Clonidine; Delirium; Hospitalization; H | 2003 |
Delirium in the older hospitalized patient.
Topics: Aged; Anti-Anxiety Agents; Antipsychotic Agents; Confusion; Delirium; Glasgow Coma Scale; Haloperido | 2005 |
A16-year-old girl with excited catatonia treated with low-dose oral Lorazepam.
Topics: Adolescent; Bipolar Disorder; Catatonia; Delirium; Dose-Response Relationship, Drug; Female; Humans; | 2005 |
Lorazepam is an independent risk factor for transitioning to delirium in intensive care unit patients.
Topics: Age Factors; Aged; Analgesics, Opioid; Antipsychotic Agents; APACHE; Coma; Critical Care; Delirium; | 2006 |
Lorazepam is an independent risk factor for transitioning to delirium in intensive care unit patients.
Topics: Age Factors; Aged; Analgesics, Opioid; Antipsychotic Agents; APACHE; Coma; Critical Care; Delirium; | 2006 |
Lorazepam is an independent risk factor for transitioning to delirium in intensive care unit patients.
Topics: Age Factors; Aged; Analgesics, Opioid; Antipsychotic Agents; APACHE; Coma; Critical Care; Delirium; | 2006 |
Lorazepam is an independent risk factor for transitioning to delirium in intensive care unit patients.
Topics: Age Factors; Aged; Analgesics, Opioid; Antipsychotic Agents; APACHE; Coma; Critical Care; Delirium; | 2006 |
Lorazepam is an independent risk factor for transitioning to delirium in intensive care unit patients.
Topics: Age Factors; Aged; Analgesics, Opioid; Antipsychotic Agents; APACHE; Coma; Critical Care; Delirium; | 2006 |
Lorazepam is an independent risk factor for transitioning to delirium in intensive care unit patients.
Topics: Age Factors; Aged; Analgesics, Opioid; Antipsychotic Agents; APACHE; Coma; Critical Care; Delirium; | 2006 |
Lorazepam is an independent risk factor for transitioning to delirium in intensive care unit patients.
Topics: Age Factors; Aged; Analgesics, Opioid; Antipsychotic Agents; APACHE; Coma; Critical Care; Delirium; | 2006 |
Lorazepam is an independent risk factor for transitioning to delirium in intensive care unit patients.
Topics: Age Factors; Aged; Analgesics, Opioid; Antipsychotic Agents; APACHE; Coma; Critical Care; Delirium; | 2006 |
Lorazepam is an independent risk factor for transitioning to delirium in intensive care unit patients.
Topics: Age Factors; Aged; Analgesics, Opioid; Antipsychotic Agents; APACHE; Coma; Critical Care; Delirium; | 2006 |
Lorazepam is an independent risk factor for transitioning to delirium in intensive care unit patients.
Topics: Age Factors; Aged; Analgesics, Opioid; Antipsychotic Agents; APACHE; Coma; Critical Care; Delirium; | 2006 |
Lorazepam is an independent risk factor for transitioning to delirium in intensive care unit patients.
Topics: Age Factors; Aged; Analgesics, Opioid; Antipsychotic Agents; APACHE; Coma; Critical Care; Delirium; | 2006 |
Lorazepam is an independent risk factor for transitioning to delirium in intensive care unit patients.
Topics: Age Factors; Aged; Analgesics, Opioid; Antipsychotic Agents; APACHE; Coma; Critical Care; Delirium; | 2006 |
Lorazepam is an independent risk factor for transitioning to delirium in intensive care unit patients.
Topics: Age Factors; Aged; Analgesics, Opioid; Antipsychotic Agents; APACHE; Coma; Critical Care; Delirium; | 2006 |
Lorazepam is an independent risk factor for transitioning to delirium in intensive care unit patients.
Topics: Age Factors; Aged; Analgesics, Opioid; Antipsychotic Agents; APACHE; Coma; Critical Care; Delirium; | 2006 |
Lorazepam is an independent risk factor for transitioning to delirium in intensive care unit patients.
Topics: Age Factors; Aged; Analgesics, Opioid; Antipsychotic Agents; APACHE; Coma; Critical Care; Delirium; | 2006 |
Lorazepam is an independent risk factor for transitioning to delirium in intensive care unit patients.
Topics: Age Factors; Aged; Analgesics, Opioid; Antipsychotic Agents; APACHE; Coma; Critical Care; Delirium; | 2006 |
Perioperative haloperidol to prevent postoperative delirium.
Topics: Aged; Anti-Anxiety Agents; Antipsychotic Agents; Delirium; Dose-Response Relationship, Drug; Drug Th | 2006 |
Anticholinergic drug-induced delirium in an elderly Alzheimer's dementia patient.
Topics: Acute Disease; Aged, 80 and over; Alzheimer Disease; Amitriptyline; Antipsychotic Agents; Cholinergi | 2007 |
GABA(A) versus GABA(B) in catatonia.
Topics: Anxiety Disorders; Catatonia; Chest Pain; Delirium; GABA Modulators; Humans; Lorazepam; Male; Middle | 2007 |
Sedation with dexmedetomidine vs lorazepam in mechanically ventilated patients.
Topics: Conscious Sedation; Delirium; Dexmedetomidine; Humans; Hypnotics and Sedatives; Lorazepam; Research | 2008 |
Iatrogenic delirium and coma: a "near miss".
Topics: Aged; Coma; Coronary Artery Bypass; Coronary Stenosis; Delirium; Electrocardiography; Female; Follow | 2008 |
Steroid psychosis after orthognathic surgery: a case report.
Topics: Adult; Anti-Inflammatory Agents; Antipsychotic Agents; Delirium; Delusions; Dexamethasone; Haloperid | 1997 |
Steroid psychosis after orthognathic surgery: a case report.
Topics: Adult; Anti-Inflammatory Agents; Antipsychotic Agents; Delirium; Delusions; Dexamethasone; Haloperid | 1997 |
Steroid psychosis after orthognathic surgery: a case report.
Topics: Adult; Anti-Inflammatory Agents; Antipsychotic Agents; Delirium; Delusions; Dexamethasone; Haloperid | 1997 |
Steroid psychosis after orthognathic surgery: a case report.
Topics: Adult; Anti-Inflammatory Agents; Antipsychotic Agents; Delirium; Delusions; Dexamethasone; Haloperid | 1997 |
Abuse of topical analgesic.
Topics: Administration, Topical; Alcoholism; Analgesics, Non-Narcotic; Delirium; Fentanyl; Humans; Infusions | 2001 |
Ketamine-iorazepam. Attenuation of psychic sequelae of ketamine by lorazepam.
Topics: Adult; Anesthesia, Intravenous; Anti-Anxiety Agents; Delirium; Female; Humans; Ketamine; Lorazepam; | 1978 |
Sedative and hypnotic withdrawal states in hospitalised patients.
Topics: Aged; Delirium; Female; Hospitalization; Humans; Lorazepam; Substance Withdrawal Syndrome | 1991 |
Emergency intravenous sedation of the delirious, medically ill patient.
Topics: Critical Care; Delirium; Drug Therapy, Combination; Haloperidol; Humans; Hydromorphone; Infusions, I | 1988 |
A case of psychosis and delirium following withdrawal from triazolam.
Topics: Delirium; Humans; Lorazepam; Male; Middle Aged; Psychoses, Substance-Induced; Substance Withdrawal S | 1987 |
Emergency pharmacotherapy of delirium in the critically ill cancer patient.
Topics: Adult; Aged; Delirium; Drug Therapy, Combination; Emergencies; Female; Haloperidol; Humans; Infusion | 1986 |
Inpatient clinical trial of lorazepam for the management of manic agitation.
Topics: Adult; Ataxia; Bipolar Disorder; Delirium; Female; Humans; Lorazepam; Male; Middle Aged; Mood Disord | 1985 |