lorazepam has been researched along with Cystic Fibrosis of Pancreas in 3 studies
Lorazepam: A benzodiazepine used as an anti-anxiety agent with few side effects. It also has hypnotic, anticonvulsant, and considerable sedative properties and has been proposed as a preanesthetic agent.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The plasma disposition of three model substrates (lorazepam, indocyanine green, and antipyrine) and the formation clearance of antipyrine metabolites (3-hydroxymethylantipyrine, norantipyrine, and 4-hydroxyantipyrine) were evaluated in 15 subjects with mild cystic fibrosis and in 15 healthy control subjects." | 3.69 | Hepatic drug clearance in patients with mild cystic fibrosis. ( Crom, WR; Evans, WE; Karlson, KH; Kearns, GL; Mallory, GB, 1996) |
| "To examine whether hepatic drug metabolism is altered in patients with cystic fibrosis (CF), we evaluated the pharmacokinetics of three model pharmacologic substrates (antipyrine, a marker of hepatic oxidative metabolism; lorazepam, a marker of hepatic glucuronosyltransferase activity; and indocyanine green (ICG), a marker of hepatic blood flow and biliary secretion) in 14 patients with CF (14." | 3.68 | Enhanced hepatic drug clearance in patients with cystic fibrosis. ( Crom, WR; Evans, WE; Kearns, GL; Mallory, GB, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lewis, D | 1 |
| Blow, A | 1 |
| Tye, J | 1 |
| Hew-Butler, T | 1 |
| Kearns, GL | 2 |
| Crom, WR | 2 |
| Karlson, KH | 1 |
| Mallory, GB | 2 |
| Evans, WE | 2 |
3 other studies available for lorazepam and Cystic Fibrosis of Pancreas
| Article | Year |
|---|---|
Considering exercise-associated hyponatraemia as a continuum.
Topics: Adult; Aftercare; Anticonvulsants; Antidiuretic Agents; Confusion; Cystic Fibrosis; Deamino Arginine | 2018 |
Hepatic drug clearance in patients with mild cystic fibrosis.
Topics: Adolescent; Adult; Anti-Anxiety Agents; Anti-Inflammatory Agents, Non-Steroidal; Antipyrine; Bile; C | 1996 |
Enhanced hepatic drug clearance in patients with cystic fibrosis.
Topics: Adolescent; Adult; Antipyrine; Biotransformation; Cystic Fibrosis; Female; Humans; Indocyanine Green | 1990 |