lorazepam has been researched along with Constitutional Liver Dysfunction in 2 studies
Lorazepam: A benzodiazepine used as an anti-anxiety agent with few side effects. It also has hypnotic, anticonvulsant, and considerable sedative properties and has been proposed as a preanesthetic agent.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Lorazepam clearances were also 20-40% lower in patients with Gilbert's syndrome compared with normals when studied fasting and with neo/chol, or fed and in the control state (P < 0." | 2.67 | Disposition of lorazepam in Gilbert's syndrome: effects of fasting, feeding, and enterohepatic circulation. ( Chaudhary, A; Herman, RJ; Szakacs, CB, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Shader, RI | 1 |
| Divoll, M | 1 |
| Greenblatt, DJ | 1 |
| Herman, RJ | 1 |
| Chaudhary, A | 1 |
| Szakacs, CB | 1 |
1 trial available for lorazepam and Constitutional Liver Dysfunction
| Article | Year |
|---|---|
Disposition of lorazepam in Gilbert's syndrome: effects of fasting, feeding, and enterohepatic circulation.
Topics: Adolescent; Adult; Biological Availability; Cholestyramine Resin; Chromatography, High Pressure Liqu | 1994 |
1 other study available for lorazepam and Constitutional Liver Dysfunction
| Article | Year |
|---|---|
Kinetics of oxazepam and lorazepam in two subjects with Gilbert syndrome.
Topics: Adult; Anti-Anxiety Agents; Gilbert Disease; Humans; Hyperbilirubinemia, Hereditary; Kinetics; Loraz | 1981 |