lorazepam has been researched along with Coma in 26 studies
Lorazepam: A benzodiazepine used as an anti-anxiety agent with few side effects. It also has hypnotic, anticonvulsant, and considerable sedative properties and has been proposed as a preanesthetic agent.
Coma: A profound state of unconsciousness associated with depressed cerebral activity from which the individual cannot be aroused. Coma generally occurs when there is dysfunction or injury involving both cerebral hemispheres or the brain stem RETICULAR FORMATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Of the 103 patients randomized, 63 (31 dexmedetomidine; 32 lorazepam) were admitted with sepsis and 40 (21 dexmedetomidine; 19 lorazepam) without sepsis." | 9.14 | Effect of dexmedetomidine versus lorazepam on outcome in patients with sepsis: an a priori-designed analysis of the MENDS randomized controlled trial. ( Ely, EW; Girard, TD; Herr, DL; Maze, M; McGrane, S; Pandharipande, PP; Sanders, RD; Shintani, AK; Thompson, JL, 2010) |
| "Lorazepam was an independent risk factor for daily transition to delirium (odds ratio, 1." | 7.73 | Lorazepam is an independent risk factor for transitioning to delirium in intensive care unit patients. ( Bernard, GR; Dittus, RS; Ely, EW; Pandharipande, P; Peterson, J; Pun, BT; Shintani, A; Wilkinson, GR, 2006) |
| "The purpose of this report is to describe the use of flumazenil as a diagnostic aid in the differential diagnosis of coma in a patient with an inadvertent overdose of benzodiazepines." | 7.69 | Flumazenil as a diagnostic tool in the differential diagnosis of coma in a critically ill patient. ( McLachlan, RS; Sharpe, MD; Sprenger, H, 1994) |
| "Doxepin is a tricyclic antidepressant from the group of dibenzoxepines." | 5.38 | [Prolonged toxic coma and anisocoria secondary to doxepin, lorazepam and phenobarbital poisoning--case study]. ( Kołodziej, M; Krajewska, A; Majewska, M; Szponar, J, 2012) |
| "Of the 103 patients randomized, 63 (31 dexmedetomidine; 32 lorazepam) were admitted with sepsis and 40 (21 dexmedetomidine; 19 lorazepam) without sepsis." | 5.14 | Effect of dexmedetomidine versus lorazepam on outcome in patients with sepsis: an a priori-designed analysis of the MENDS randomized controlled trial. ( Ely, EW; Girard, TD; Herr, DL; Maze, M; McGrane, S; Pandharipande, PP; Sanders, RD; Shintani, AK; Thompson, JL, 2010) |
| "Lorazepam is currently recommended for sustained sedation of mechanically ventilated intensive care unit (ICU) patients, but this and other benzodiazepine drugs may contribute to acute brain dysfunction, ie, delirium and coma, associated with prolonged hospital stays, costs, and increased mortality." | 5.12 | Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial. ( Bernard, GR; Deppen, SA; Dittus, RS; Ely, EW; Girard, TD; Herr, DL; Jackson, JC; Maze, M; Miller, RR; Pandharipande, PP; Pun, BT; Shintani, AK; Stiles, RA; Thompson, JL, 2007) |
| "Lorazepam was an independent risk factor for daily transition to delirium (odds ratio, 1." | 3.73 | Lorazepam is an independent risk factor for transitioning to delirium in intensive care unit patients. ( Bernard, GR; Dittus, RS; Ely, EW; Pandharipande, P; Peterson, J; Pun, BT; Shintani, A; Wilkinson, GR, 2006) |
| "The purpose of this report is to describe the use of flumazenil as a diagnostic aid in the differential diagnosis of coma in a patient with an inadvertent overdose of benzodiazepines." | 3.69 | Flumazenil as a diagnostic tool in the differential diagnosis of coma in a critically ill patient. ( McLachlan, RS; Sharpe, MD; Sprenger, H, 1994) |
| "The prognosis of CCI patients with coma or delirium has not yet been thoroughly studied, but preliminary studies suggest this population is at high risk for detrimental outcomes associated with acute brain dysfunction." | 2.48 | Brain dysfunction in patients with chronic critical illness. ( Girard, TD, 2012) |
| " Our objective was to evaluate BZD dosing in SE patients and its effects on clinical/electrographic outcomes." | 1.48 | Inadequate benzodiazepine dosing may result in progression to refractory and non-convulsive status epilepticus. ( Ibrahim, M; Mahulikar, A; Mohamed, W; Rao, SK; Seraji-Bozorgzad, N; Shah, A, 2018) |
| "The incidence of coma was significantly higher, and the length of hospital stay significantly longer in elderly." | 1.43 | Benzodiazepine poisoning in elderly. ( Djordjević, S; Ercegović, GV; Segrt, Z; Stosić, JJ; Vukcević, NP, 2016) |
| "Doxepin is a tricyclic antidepressant from the group of dibenzoxepines." | 1.38 | [Prolonged toxic coma and anisocoria secondary to doxepin, lorazepam and phenobarbital poisoning--case study]. ( Kołodziej, M; Krajewska, A; Majewska, M; Szponar, J, 2012) |
| "A 37-year-old woman presented with coma unresponsive to naloxone following topiramate ingestion." | 1.36 | Clinical effects and toxicokinetic evaluation following massive topiramate ingestion. ( Krasowski, MD; Lynch, MJ; Pizon, AF; Siam, MG, 2010) |
| "Lorazepam was most frequently ingested (13/41 identified drugs, 32%)." | 1.30 | Pediatric benzodiazepine ingestion resulting in hospitalization. ( Wiley, CC; Wiley, JF, 1998) |
| "This resulted in a comatose state with depression of some brainstem reflexes." | 1.27 | Spindle coma in benzodiazepine toxicity: case report. ( Mouradian, MD; Penovich, PE, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (19.23) | 18.7374 |
| 1990's | 4 (15.38) | 18.2507 |
| 2000's | 10 (38.46) | 29.6817 |
| 2010's | 6 (23.08) | 24.3611 |
| 2020's | 1 (3.85) | 2.80 |
| Authors | Studies |
|---|---|
| Spiegel, DR | 1 |
| Ayzman, A | 1 |
| Reid, FE | 1 |
| Ahuja, K | 1 |
| Worfolk, J | 1 |
| Rao, SK | 1 |
| Mahulikar, A | 1 |
| Ibrahim, M | 1 |
| Shah, A | 1 |
| Seraji-Bozorgzad, N | 1 |
| Mohamed, W | 1 |
| Vukcević, NP | 1 |
| Ercegović, GV | 1 |
| Segrt, Z | 1 |
| Djordjević, S | 1 |
| Stosić, JJ | 1 |
| Portilla-Botelho, M | 1 |
| Ortega-Carnicer, J | 1 |
| Gómez-Grande, ML | 1 |
| Martín-Rodríguez, C | 1 |
| Pandharipande, PP | 2 |
| Sanders, RD | 1 |
| Girard, TD | 3 |
| McGrane, S | 1 |
| Thompson, JL | 2 |
| Shintani, AK | 2 |
| Herr, DL | 2 |
| Maze, M | 2 |
| Ely, EW | 3 |
| Lynch, MJ | 1 |
| Pizon, AF | 1 |
| Siam, MG | 1 |
| Krasowski, MD | 1 |
| Kołodziej, M | 1 |
| Majewska, M | 1 |
| Krajewska, A | 1 |
| Szponar, J | 1 |
| Gaspari, R | 1 |
| Arcangeli, A | 1 |
| Mensi, S | 1 |
| Wismayer, DS | 1 |
| Tartaglione, T | 1 |
| Antuzzi, D | 1 |
| Conti, G | 1 |
| Proietti, R | 1 |
| Granot, R | 1 |
| Berkovic, SF | 1 |
| Patterson, S | 1 |
| Hopwood, M | 1 |
| Mackenzie, R | 1 |
| Haller, M | 1 |
| Kiefer, K | 1 |
| Vogt, H | 1 |
| Huang, TL | 1 |
| Pandharipande, P | 1 |
| Shintani, A | 1 |
| Peterson, J | 1 |
| Pun, BT | 2 |
| Wilkinson, GR | 1 |
| Dittus, RS | 2 |
| Bernard, GR | 2 |
| Alisky, JM | 1 |
| Miller, RR | 1 |
| Jackson, JC | 1 |
| Deppen, SA | 1 |
| Stiles, RA | 1 |
| Dunn, WF | 1 |
| Adams, SC | 1 |
| Adams, RW | 1 |
| Guterman, B | 1 |
| Sebastian, P | 1 |
| Sodha, N | 1 |
| Jäger, U | 1 |
| Hruby, K | 1 |
| Haubenstock, A | 1 |
| Fasching, I | 1 |
| Shaw, WL | 1 |
| Sprenger, H | 1 |
| Sharpe, MD | 1 |
| McLachlan, RS | 1 |
| Wiley, CC | 1 |
| Wiley, JF | 1 |
| Lugaresi, E | 1 |
| Montagna, P | 1 |
| Tinuper, P | 1 |
| Plazzi, G | 1 |
| Gallassi, R | 1 |
| Heard, K | 1 |
| O'Malley, GF | 1 |
| Dart, RC | 1 |
| Lee, SA | 1 |
| Lee, JK | 1 |
| Heo, K | 1 |
| Wetzel, H | 1 |
| Heuser, I | 1 |
| Benkert, O | 1 |
| Mouradian, MD | 1 |
| Penovich, PE | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Randomized, Double-blind Trial in Ventilated ICU Patients Comparing Treatment With an Alpha2 Agonist Versus a Gamma Aminobutyric Acid (GABA)-Agonist to Determine Delirium Rates, Efficacy of Sedation, Analgesia and Discharge Cognitive Status[NCT00095251] | Phase 2 | 100 participants (Anticipated) | Interventional | 2004-08-31 | Completed | ||
| PRO-DEFENSE: Propofol Versus Dexmedetomidine for Sedation in Mechanically Ventilated Patients With Sepsis[NCT02203019] | Phase 4 | 36 participants (Actual) | Interventional | 2014-08-31 | Completed | ||
| Multicentric, Single Blind, Randomized Controlled Trial on Enteral Sedation Versus Intravenous Sedation in Critically Ill High-risk ICU Patients[NCT01360346] | Phase 3 | 300 participants (Anticipated) | Interventional | 2012-01-31 | Recruiting | ||
| Pain, Agitation and Delirium Protocol in Ventilated Patients in the Duke CICU[NCT02903407] | Phase 4 | 7 participants (Actual) | Interventional | 2017-09-01 | Terminated (stopped due to All enrolled participants completed the study protocol but the study was terminated prior to the goal number of participants due to low recruitment) | ||
| Effect of Flumazenil on Hypoactive Delirium in the ICU: A Double-Blind, Placebo-Controlled Pilot Study[NCT02899156] | Phase 4 | 22 participants (Actual) | Interventional | 2016-03-31 | Terminated (stopped due to A planned interim analysis led to the trial being stopped early based on the observed size effect and power analysis.) | ||
| A Randomized Control Trial Using the BIS Monitor to Avoid Over Sedation and Prolonged Neuropsychological Deficits in Mechanically Ventilated ICU Patients[NCT00469482] | 28 participants (Actual) | Interventional | 2007-06-30 | Completed | |||
| Haloperidol vs Olanzapine for the Management of ICU Delirium: A Randomized Clinical Trial[NCT00833300] | 200 participants (Anticipated) | Interventional | 2008-06-30 | Terminated | |||
| Randomized, Placebo Controlled, Pilot Trial of Statin Use in Burn Patients[NCT00978419] | Phase 2 | 40 participants (Actual) | Interventional | 2010-03-31 | Completed | ||
| Impact of Dexmedetomidine Supplemented Analgesia on Long-term Survival in Elderly Patients After Cancer Surgery: a Multicenter Randomized Controlled Trial[NCT03012971] | 1,500 participants (Actual) | Interventional | 2017-01-06 | Active, not recruiting | |||
| Low-dose Dexmedetomidine for Delirium Prevention in Mechanically Ventilated Patients in Intensive Care Unit: a Multicenter, Randomised, Double-blinded, Placebo-controlled Trial[NCT03172897] | Phase 4 | 260 participants (Anticipated) | Interventional | 2017-08-20 | Suspended (stopped due to The trial was stopped because of difficulty in recruiting patients (another trial had similar inclusion/exclusion criteria). No patients was recruited in this trial.) | ||
| Phenobarbital Versus Ativan for Refractory Alcohol Withdrawal Treatment in the Intensive Care Unit[NCT04156464] | Phase 4 | 142 participants (Anticipated) | Interventional | 2020-07-06 | Recruiting | ||
| Dynamic Light Application to Prevent ICU Acquired Delirium[NCT01274819] | 1,000 participants (Actual) | Interventional | 2011-07-31 | Completed | |||
| Impact of Low-Dose Dexmedetomidine on Sleep Quality in Mechanical Ventilation Patients After Surgery in Intensive Care Unit: a Pilot Randomized, Double-Blind, Placebo-Controlled Trial[NCT03335527] | Phase 4 | 80 participants (Actual) | Interventional | 2017-11-17 | Completed | ||
| Impact of Dexmedetomidine Supplemented Analgesia on Incidence of Delirium in Elderly Patients After Cancer Surgery: a Multicenter Randomized Controlled Trial[NCT03012984] | 1,500 participants (Actual) | Interventional | 2017-01-06 | Completed | |||
| Effect of Low-dose Dexmedetomidine on Postoperative Delirium in Patients After Cardiac Surgery: A Multicenter, Double-blinded, Randomized Controlled Trial[NCT03624595] | 502 participants (Anticipated) | Interventional | 2019-04-16 | Active, not recruiting | |||
| Awakening-Breathing Coordination, Delirium Monitoring/Management & Early Mobility (ABCDE) Protocol[NCT01413009] | 200 participants (Actual) | Observational | 2010-12-29 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Number of days patient requires mechanical ventilation (NCT02203019)
Timeframe: Up to 28 days
| Intervention | days (Median) |
|---|---|
| Propofol | 5 |
| Dexmedetomidine | 3 |
Number of days patient stays in the MICU (NCT02203019)
Timeframe: Up to 28 Days
| Intervention | days (Median) |
|---|---|
| Propofol | 6 |
| Dexmedetomidine | 5 |
Number of days the patient requires intravenous vasopressors (NCT02203019)
Timeframe: Up to 28 Days
| Intervention | days (Median) |
|---|---|
| Propofol | 0 |
| Dexmedetomidine | 2 |
Number of patients who die within 28 days after randomization (NCT02203019)
Timeframe: Up to 28 Days
| Intervention | Participants (Count of Participants) |
|---|---|
| Propofol | 8 |
| Dexmedetomidine | 9 |
Index hospitalization length of stay in days (NCT02903407)
Timeframe: One month or hospital discharge, whichever time point comes first
| Intervention | Days (Median) |
|---|---|
| Midazolam | 19.5 |
| Propofol or Dexmedetomidine | 30.0 |
All-cause mortality during the hospitalization (NCT02903407)
Timeframe: One month or hospital discharge, whichever time point comes first
| Intervention | participants (Number) |
|---|---|
| Midazolam | 1 |
| Propofol or Dexmedetomidine | 1 |
Number of days of admission to the CICU during the index hospitalization (NCT02903407)
Timeframe: One month or hospital discharge, whichever time point comes first
| Intervention | Days (Median) |
|---|---|
| Midazolam | 4.1 |
| Propofol or Dexmedetomidine | 10.0 |
The number of days alive and free from delirium or coma during admission will be evaluated among patients with CAM-ICU documented (NCT02903407)
Timeframe: One month or hospital discharge, whichever time point comes first
| Intervention | Days (Median) |
|---|---|
| Midazolam | 14.0 |
The time (in days) from when the clinical care team documents a decision to pursue extubation until the time the patient was extubated (NCT02903407)
Timeframe: One month or hospital discharge, whichever time point comes first
| Intervention | Days (Median) |
|---|---|
| Midazolam | 0 |
| Propofol or Dexmedetomidine | 0 |
Following ICU discharge, patient charts will be reviewed to evaluate whether they required reintubation. If so, will determine whether necessity of reintubation was related to delirium. (NCT02903407)
Timeframe: One month or hospital discharge, whichever time point comes first
| Intervention | Participants (Count of Participants) |
|---|---|
| Midazolam | 0 |
| Propofol or Dexmedetomidine | 1 |
Patients will be monitored for bradycardia which may be associated with sedation drug. Average heart rate before, during and after use of drug will be recorded for each patient. (NCT02903407)
Timeframe: One month or hospital discharge, whichever time point comes first
| Intervention | Participants (Count of Participants) |
|---|---|
| Midazolam | 0 |
| Propofol or Dexmedetomidine | 0 |
Will use the Confusion Assessment Method for the ICU (CAM-ICU) to assess presence of delirium as per standard of care by nurses in the CICU. Patients with CAM-ICU data recorded will be included. (NCT02903407)
Timeframe: One month or hospital discharge, whichever time point comes first
| Intervention | Participants (Count of Participants) |
|---|---|
| Midazolam | 1 |
Patients will be monitored for increased pressor requirement during the CICU stay (NCT02903407)
Timeframe: One month or hospital discharge, whichever time point comes first
| Intervention | Participants (Count of Participants) |
|---|---|
| Midazolam | 2 |
| Propofol or Dexmedetomidine | 2 |
Days requiring mechanical ventilation during the initial episode of intubation during the hospitalization (NCT02903407)
Timeframe: One month or hospital discharge, whichever time point comes first
| Intervention | Days (Median) |
|---|---|
| Midazolam | 2.5 |
| Propofol or Dexmedetomidine | 6.8 |
Will use the CPOT (Critical-Care Pain Observation Tool) score to assess pain level as per standard of care by nurses in the CICU. The CPOT has a range of 0 to 8. A CPOT score of ≤ 2 = minimal to no pain present and >2 = unacceptable level of pain. Data that is recorded will be evaluated following discharge. (NCT02903407)
Timeframe: One month or hospital discharge, whichever time point comes first
| Intervention | score on a scale (Median) |
|---|---|
| Midazolam | 0.0 |
| Propofol or Dexmedetomidine | 0.0 |
Will use RASS (Richmond Agitation and Sedation Scale) to assess level of sedation as per standard of care by nurses in the CICU. Data that is recorded will be evaluated following discharge. The RASS ranges from -5 (unrousable) to +4 (combative) and 0 (zero) = alert and calm and goal sedation is considered a RASS level of 0 to -2. (NCT02903407)
Timeframe: One month or hospital discharge, whichever time point comes first
| Intervention | percentage of time (Median) |
|---|---|
| Midazolam | 63.3 |
| Propofol or Dexmedetomidine | 63.2 |
The duration, in days, from withdrawal of sedation for mechanical ventilation until the time of discharge from the ICU (NCT02903407)
Timeframe: One month or hospital discharge, whichever time point comes first
| Intervention | Days (Median) |
|---|---|
| Midazolam | 1.6 |
| Propofol or Dexmedetomidine | 5.6 |
average duration of time patient was randomized to each infusion up to 72 hours (NCT02899156)
Timeframe: up to 72 hours after the start of the infusion
| Intervention | hours (Mean) |
|---|---|
| Flumazenil Group | 54.8 |
| Placebo Group | 58.2 |
average maximum rate (ml/hr) during the 72 hours after study infusion (NCT02899156)
Timeframe: up to 72 hours after the start of the infusion
| Intervention | milliliters per hour (Mean) |
|---|---|
| Flumazenil Group | 5 |
| Placebo Group | 5.2 |
length of time that the patient was admitted to an intensive care unit service during the hospital stay (NCT02899156)
Timeframe: duration of admission to the intensive care unit
| Intervention | days (Mean) |
|---|---|
| Flumazenil Group | 7.8 |
| Placebo Group | 7 |
Defined by the number of days in the 14-day period after randomization that the patient was alive and not delirious (i.e. CAM-ICU negative). Zero delirium-free days will be observed for patients that die within the 14-day period. (NCT02899156)
Timeframe: up to 14 days after randomization
| Intervention | days (Median) |
|---|---|
| Flumazenil Group | 12.7 |
| Placebo Group | 9.2 |
number of days within the first 28 days after enrollment that the patient was free from needing mechanical ventilation (NCT02899156)
Timeframe: up to 28 days after randomization
| Intervention | days (Mean) |
|---|---|
| Flumazenil Group | 23.6 |
| Placebo Group | 24.9 |
defined by the proportion of patients who were delirium free at 14 days after randomization (NCT02899156)
Timeframe: up to 14 days after randomization
| Intervention | Participants (Count of Participants) |
|---|---|
| Flumazenil Group | 9 |
| Placebo Group | 7 |
number of times that a RASS score of + 2 to +4 occurred that did not resolve with decreasing study infusion (NCT02899156)
Timeframe: up to 72 hours after the start of the infusion
| Intervention | Participants (Count of Participants) |
|---|---|
| Flumazenil Group | 0 |
| Placebo Group | 0 |
1 review available for lorazepam and Coma
| Article | Year |
|---|---|
Brain dysfunction in patients with chronic critical illness.
Topics: Antipsychotic Agents; Attention Deficit Disorder with Hyperactivity; Chronic Disease; Coma; Comorbid | 2012 |
2 trials available for lorazepam and Coma
| Article | Year |
|---|---|
Effect of dexmedetomidine versus lorazepam on outcome in patients with sepsis: an a priori-designed analysis of the MENDS randomized controlled trial.
Topics: Adult; Aged; Coma; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypnotics and Sed | 2010 |
Effect of dexmedetomidine versus lorazepam on outcome in patients with sepsis: an a priori-designed analysis of the MENDS randomized controlled trial.
Topics: Adult; Aged; Coma; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypnotics and Sed | 2010 |
Effect of dexmedetomidine versus lorazepam on outcome in patients with sepsis: an a priori-designed analysis of the MENDS randomized controlled trial.
Topics: Adult; Aged; Coma; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypnotics and Sed | 2010 |
Effect of dexmedetomidine versus lorazepam on outcome in patients with sepsis: an a priori-designed analysis of the MENDS randomized controlled trial.
Topics: Adult; Aged; Coma; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypnotics and Sed | 2010 |
Effect of dexmedetomidine versus lorazepam on outcome in patients with sepsis: an a priori-designed analysis of the MENDS randomized controlled trial.
Topics: Adult; Aged; Coma; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypnotics and Sed | 2010 |
Effect of dexmedetomidine versus lorazepam on outcome in patients with sepsis: an a priori-designed analysis of the MENDS randomized controlled trial.
Topics: Adult; Aged; Coma; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypnotics and Sed | 2010 |
Effect of dexmedetomidine versus lorazepam on outcome in patients with sepsis: an a priori-designed analysis of the MENDS randomized controlled trial.
Topics: Adult; Aged; Coma; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypnotics and Sed | 2010 |
Effect of dexmedetomidine versus lorazepam on outcome in patients with sepsis: an a priori-designed analysis of the MENDS randomized controlled trial.
Topics: Adult; Aged; Coma; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypnotics and Sed | 2010 |
Effect of dexmedetomidine versus lorazepam on outcome in patients with sepsis: an a priori-designed analysis of the MENDS randomized controlled trial.
Topics: Adult; Aged; Coma; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypnotics and Sed | 2010 |
Effect of dexmedetomidine versus lorazepam on outcome in patients with sepsis: an a priori-designed analysis of the MENDS randomized controlled trial.
Topics: Adult; Aged; Coma; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypnotics and Sed | 2010 |
Effect of dexmedetomidine versus lorazepam on outcome in patients with sepsis: an a priori-designed analysis of the MENDS randomized controlled trial.
Topics: Adult; Aged; Coma; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypnotics and Sed | 2010 |
Effect of dexmedetomidine versus lorazepam on outcome in patients with sepsis: an a priori-designed analysis of the MENDS randomized controlled trial.
Topics: Adult; Aged; Coma; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypnotics and Sed | 2010 |
Effect of dexmedetomidine versus lorazepam on outcome in patients with sepsis: an a priori-designed analysis of the MENDS randomized controlled trial.
Topics: Adult; Aged; Coma; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypnotics and Sed | 2010 |
Effect of dexmedetomidine versus lorazepam on outcome in patients with sepsis: an a priori-designed analysis of the MENDS randomized controlled trial.
Topics: Adult; Aged; Coma; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypnotics and Sed | 2010 |
Effect of dexmedetomidine versus lorazepam on outcome in patients with sepsis: an a priori-designed analysis of the MENDS randomized controlled trial.
Topics: Adult; Aged; Coma; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypnotics and Sed | 2010 |
Effect of dexmedetomidine versus lorazepam on outcome in patients with sepsis: an a priori-designed analysis of the MENDS randomized controlled trial.
Topics: Adult; Aged; Coma; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypnotics and Sed | 2010 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypn | 2007 |
23 other studies available for lorazepam and Coma
| Article | Year |
|---|---|
Catatonic Coma in a Patient With Schizophrenia Receiving Palliative Care With Reversal of Symptoms With Lorazepam.
Topics: Catatonia; Coma; Humans; Lorazepam; Palliative Care; Schizophrenia | 2023 |
Inadequate benzodiazepine dosing may result in progression to refractory and non-convulsive status epilepticus.
Topics: Adult; Aged; Anticonvulsants; Benzodiazepines; Coma; Disease Progression; Drug Resistant Epilepsy; F | 2018 |
Benzodiazepine poisoning in elderly.
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Antidotes; Benzodiazepines; Bromazepam; Coh | 2016 |
[Paroxetine-induced severe hyponatremic rhabdomyolisis].
Topics: Cations; Coma; Depressive Disorder; Diagnosis, Differential; Epilepsy, Tonic-Clonic; Female; Humans; | 2008 |
Clinical effects and toxicokinetic evaluation following massive topiramate ingestion.
Topics: Acidosis; Adult; Anticonvulsants; Bipolar Disorder; Blood Gas Analysis; Coma; Critical Care; Drug Ov | 2010 |
[Prolonged toxic coma and anisocoria secondary to doxepin, lorazepam and phenobarbital poisoning--case study].
Topics: Antidepressive Agents, Tricyclic; Coma; Complex Mixtures; Doxepin; Drug Overdose; Drug Synergism; Hu | 2012 |
Late-onset presentation of ornithine transcarbamylase deficiency in a young woman with hyperammonemic coma.
Topics: Adult; Age Factors; Anticonvulsants; Brain; Citrulline; Coma; Diagnosis, Differential; Electroenceph | 2003 |
Idiopathic recurrent stupor: a warning.
Topics: Aged; Coma; Crime; Humans; Lorazepam; Male; Oxazepam; Periodicity; Poisoning; Spouses | 2004 |
[Dissociative stupor as a postoperative consequence of general anesthesia].
Topics: Adult; Anesthesia, General; Coma; Dissociative Disorders; Female; GABA Modulators; Humans; Laparosco | 2003 |
Lorazepam and diazepam rapidly relieve catatonic signs in patients with schizophrenia.
Topics: Adult; Anti-Anxiety Agents; Coma; Diazepam; Dose-Response Relationship, Drug; Drug Administration Sc | 2005 |
Lorazepam is an independent risk factor for transitioning to delirium in intensive care unit patients.
Topics: Age Factors; Aged; Analgesics, Opioid; Antipsychotic Agents; APACHE; Coma; Critical Care; Delirium; | 2006 |
Lorazepam is an independent risk factor for transitioning to delirium in intensive care unit patients.
Topics: Age Factors; Aged; Analgesics, Opioid; Antipsychotic Agents; APACHE; Coma; Critical Care; Delirium; | 2006 |
Lorazepam is an independent risk factor for transitioning to delirium in intensive care unit patients.
Topics: Age Factors; Aged; Analgesics, Opioid; Antipsychotic Agents; APACHE; Coma; Critical Care; Delirium; | 2006 |
Lorazepam is an independent risk factor for transitioning to delirium in intensive care unit patients.
Topics: Age Factors; Aged; Analgesics, Opioid; Antipsychotic Agents; APACHE; Coma; Critical Care; Delirium; | 2006 |
Lorazepam is an independent risk factor for transitioning to delirium in intensive care unit patients.
Topics: Age Factors; Aged; Analgesics, Opioid; Antipsychotic Agents; APACHE; Coma; Critical Care; Delirium; | 2006 |
Lorazepam is an independent risk factor for transitioning to delirium in intensive care unit patients.
Topics: Age Factors; Aged; Analgesics, Opioid; Antipsychotic Agents; APACHE; Coma; Critical Care; Delirium; | 2006 |
Lorazepam is an independent risk factor for transitioning to delirium in intensive care unit patients.
Topics: Age Factors; Aged; Analgesics, Opioid; Antipsychotic Agents; APACHE; Coma; Critical Care; Delirium; | 2006 |
Lorazepam is an independent risk factor for transitioning to delirium in intensive care unit patients.
Topics: Age Factors; Aged; Analgesics, Opioid; Antipsychotic Agents; APACHE; Coma; Critical Care; Delirium; | 2006 |
Lorazepam is an independent risk factor for transitioning to delirium in intensive care unit patients.
Topics: Age Factors; Aged; Analgesics, Opioid; Antipsychotic Agents; APACHE; Coma; Critical Care; Delirium; | 2006 |
Lorazepam is an independent risk factor for transitioning to delirium in intensive care unit patients.
Topics: Age Factors; Aged; Analgesics, Opioid; Antipsychotic Agents; APACHE; Coma; Critical Care; Delirium; | 2006 |
Lorazepam is an independent risk factor for transitioning to delirium in intensive care unit patients.
Topics: Age Factors; Aged; Analgesics, Opioid; Antipsychotic Agents; APACHE; Coma; Critical Care; Delirium; | 2006 |
Lorazepam is an independent risk factor for transitioning to delirium in intensive care unit patients.
Topics: Age Factors; Aged; Analgesics, Opioid; Antipsychotic Agents; APACHE; Coma; Critical Care; Delirium; | 2006 |
Lorazepam is an independent risk factor for transitioning to delirium in intensive care unit patients.
Topics: Age Factors; Aged; Analgesics, Opioid; Antipsychotic Agents; APACHE; Coma; Critical Care; Delirium; | 2006 |
Lorazepam is an independent risk factor for transitioning to delirium in intensive care unit patients.
Topics: Age Factors; Aged; Analgesics, Opioid; Antipsychotic Agents; APACHE; Coma; Critical Care; Delirium; | 2006 |
Lorazepam is an independent risk factor for transitioning to delirium in intensive care unit patients.
Topics: Age Factors; Aged; Analgesics, Opioid; Antipsychotic Agents; APACHE; Coma; Critical Care; Delirium; | 2006 |
Lorazepam is an independent risk factor for transitioning to delirium in intensive care unit patients.
Topics: Age Factors; Aged; Analgesics, Opioid; Antipsychotic Agents; APACHE; Coma; Critical Care; Delirium; | 2006 |
Lorazepam-reversible catatonia in the elderly can mimic dementia, coma and stroke.
Topics: Aged, 80 and over; Catatonia; Coma; Dementia; Diagnosis, Differential; GABA Modulators; Humans; Lora | 2007 |
Iatrogenic delirium and coma: a "near miss".
Topics: Aged; Coma; Coronary Artery Bypass; Coronary Stenosis; Delirium; Electrocardiography; Female; Follow | 2008 |
Recovery from alpha coma after lorazepam overdose.
Topics: Aged; Alpha Rhythm; Anti-Anxiety Agents; Coma; Humans; Lorazepam; Male | 1981 |
[Comparative clinical toxicology of 5 benzodiazepine derivatives].
Topics: Adult; Anti-Anxiety Agents; Bromazepam; Child; Coma; Diazepam; Dose-Response Relationship, Drug; Fem | 1984 |
Antidepressant medication.
Topics: Aged; Antidepressive Agents; Coma; Dibenzazepines; Female; Humans; Lorazepam; Mianserin; Middle Aged | 1981 |
Flumazenil as a diagnostic tool in the differential diagnosis of coma in a critically ill patient.
Topics: Aged; Bacterial Infections; Coma; Critical Illness; Diagnosis, Differential; Diazepam; Flumazenil; H | 1994 |
Pediatric benzodiazepine ingestion resulting in hospitalization.
Topics: Anti-Anxiety Agents; Ataxia; Benzodiazepines; Central Nervous System Diseases; Child; Child, Prescho | 1998 |
Suspected covert lorazepam administration misdiagnosed as recurrent endozepine stupor.
Topics: Anti-Anxiety Agents; Carrier Proteins; Coma; Diagnostic Errors; Diazepam Binding Inhibitor; Electroe | 1998 |
Treatment of amitriptyline poisoning with ovine antibody to tricyclic antidepressants.
Topics: Adult; Amitriptyline; Anti-Anxiety Agents; Antidepressive Agents, Tricyclic; Coma; Humans; Immunoglo | 1999 |
Coma probably induced by lorazepam-valproate interaction.
Topics: Adult; Anticonvulsants; Coma; Drug Interactions; Epilepsy; Female; Humans; Lorazepam; Valproic Acid | 2002 |
Stupor and affective state: alleviation of psychomotor disturbances by lorazepam and recurrence of symptoms after Ro 15-1788.
Topics: Adult; Carbamazepine; Coma; Depressive Disorder; Drug Interactions; Drug Therapy, Combination; Femal | 1987 |
Spindle coma in benzodiazepine toxicity: case report.
Topics: Adult; Alcohol Withdrawal Delirium; Coma; Diazepam; Drug Therapy, Combination; Electroencephalograph | 1985 |