lorazepam has been researched along with Amnesia in 49 studies
Lorazepam: A benzodiazepine used as an anti-anxiety agent with few side effects. It also has hypnotic, anticonvulsant, and considerable sedative properties and has been proposed as a preanesthetic agent.
Amnesia: Pathologic partial or complete loss of the ability to recall past experiences (AMNESIA, RETROGRADE) or to form new memories (AMNESIA, ANTEROGRADE). This condition may be of organic or psychologic origin. Organic forms of amnesia are usually associated with dysfunction of the DIENCEPHALON or HIPPOCAMPUS. (From Adams et al., Principles of Neurology, 6th ed, pp426-7)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Sixty-four patients treated with cisplatin-containing regimens were entered into a randomized, double-blinded study examining the antiemetic efficacy of metoclopramide with and without lorazepam for control of cisplatin-induced emesis." | 9.06 | Metoclopramide versus metoclopramide and lorazepam. Superiority of combined therapy in the control of cisplatin-induced emesis. ( Al-Sarraf, M; Cummings, G; Gordon, CJ; Pazdur, R; Ziccarelli, A, 1989) |
| " The results suggest that the extent of the benzodiazepines' amnesic effects--both negative (anterograde) and positive (retrograde)--depends on the dosage and type of substance." | 6.66 | Anterograde and retrograde amnesia after lormetazepam and flunitrazepam. ( Aufdembrinke, B; Fichte, K; Ott, H; Rohloff, A, 1988) |
| "This amnesia was not attributable to failures of perception." | 6.65 | A comparison between transient amnesias induced by two drugs (diazepam or lorazepam) and amnesia of organic origin. ( Bowes, JB; Brown, J; Brown, M; Horn, G; Lewis, V, 1982) |
| "Lorazepam-treated subjects were able to learn a backwards-reading task at a rate no different from controls." | 6.65 | The nature of lorazepam-induced amnesia. ( File, SE; Lister, RG, 1984) |
| "The transient amnesia produced by lorazepam has been suggested to have much in common with the permanent amnesia associated with organic brain damage." | 5.07 | A comparison of the amnesic effects of lorazepam in alcoholics and non-alcoholics. ( Hennessy, MJ; Kirkby, KC; Mallick, JL; Martin, F; Philp, M, 1993) |
| "The differences between learning in lorazepam (LOR)--or scopolamine (SCOP)--induced amnesia and learning in unaware drug-free normal subjects were examined." | 5.07 | Unaware learning versus preserved learning in pharmacologic amnesia: similarities and differences. ( Knopman, D, 1991) |
| "Sixty-four patients treated with cisplatin-containing regimens were entered into a randomized, double-blinded study examining the antiemetic efficacy of metoclopramide with and without lorazepam for control of cisplatin-induced emesis." | 5.06 | Metoclopramide versus metoclopramide and lorazepam. Superiority of combined therapy in the control of cisplatin-induced emesis. ( Al-Sarraf, M; Cummings, G; Gordon, CJ; Pazdur, R; Ziccarelli, A, 1989) |
| "It has been demonstrated previously that orally administered lorazepam can cause anterograde amnesia in young adults." | 5.05 | Differential amnestic properties of short- and long-acting benzodiazepines. ( Brocker, N; Goff, P; Khosla, N; Scharf, MB, 1984) |
| "An open-label, dose-escalation study was conducted to determine doses of lorazepam required to induce anterograde amnesia and sedation in children without producing excessive toxicity." | 3.68 | Determination of sedative and amnestic doses of lorazepam in children. ( Burwinkle, JW; Henry, DW; Klutman, NE, 1991) |
| " Psychomotor and cognitive performance measures and subject- and observer-rated behavioral responses were measured daily before dosing and for 5." | 2.66 | Evaluation of the abuse potential of methocarbamol. ( Griffiths, RR; Guarino, JJ; Kirk, WT; Preston, KL, 1989) |
| " The results suggest that the extent of the benzodiazepines' amnesic effects--both negative (anterograde) and positive (retrograde)--depends on the dosage and type of substance." | 2.66 | Anterograde and retrograde amnesia after lormetazepam and flunitrazepam. ( Aufdembrinke, B; Fichte, K; Ott, H; Rohloff, A, 1988) |
| " Results suggest that individuals who take benzodiazepines will perform less well on an anterograde memory delayed recall task completed after dosing on the sixth day of treatment, but no similar difference will be found in performance on a similar task completed just before dosing on the sixth day." | 2.66 | Anxiolytics and memory: a comparison of lorazepam and alprazolam. ( Gabrielli, WF; Goodwin, DW; Kumar, R; Mac, DS, 1987) |
| "This amnesia was not attributable to failures of perception." | 2.65 | A comparison between transient amnesias induced by two drugs (diazepam or lorazepam) and amnesia of organic origin. ( Bowes, JB; Brown, J; Brown, M; Horn, G; Lewis, V, 1982) |
| "Lorazepam was found to have a significantly greater effect on memory than placebo." | 2.65 | Effects of clorazepate, diazepam, lorazepam, and placebo on human memory. ( Healey, M; McKenna, T; Meisch, R; Pickens, R, 1983) |
| "This amnesia was smallest after lormetazepam and greatest after temazepam, which differed significantly from each other." | 2.65 | Amnesic effects of lormetazepam. ( Koshorek, G; McLenaghan, A; Roehrs, T; Roth, T; Zorick, F, 1984) |
| "Lorazepam-treated subjects were able to learn a backwards-reading task at a rate no different from controls." | 2.65 | The nature of lorazepam-induced amnesia. ( File, SE; Lister, RG, 1984) |
| "Any prolonged cognitive alterations or confusional states may have additional causes and require extensive diagnostic effort." | 1.33 | Prolonged confusional state following electroconvulsive therapy--diagnostic clues from serial electroencephalography. ( Ehrentraut, S; Hegerl, U; Henkel, V; Möller, HJ; Mulert, C; Pogarell, O; Rüther, T, 2005) |
| " The plasma concentration profile after intravenously administered lorazepam could in all cases be fitted by NONLIN to a biexponential function of time with a mean terminal (biological) half-life of 14." | 1.27 | Pharmacokinetics and bioavailability of intravenous and intramuscular lorazepam with an adjunct test of the inattention effect in humans. ( Jakobsen, P; Jensen, PB; Jensen, TS; Magnussen, I; Mondrup, K; Nielsen-Kudsk, F; Petersen, T, 1983) |
| "Lorazepam, 4 mg, was evaluated in an 18-night sleep-laboratory study involving five insomniac subjects." | 1.26 | Lorazepam-efficacy, side effects, and rebound phenomena. ( Bixler, EO; Jacoby, JA; Kales, A; Scharf, MB; Schweitzer, PK, 1982) |
| " This anterograde amnesia is dependent on the dosage used but it is always accompanied by profound drowsiness, from which the patient can be roused verbally." | 1.26 | Intramuscular premedication with lorazepam. ( Mundeleer, P, 1976) |
| "Lorazepam has been studied as preanaesthetic medication given by mouth, i." | 1.26 | Studies of drugs given before anaesthesia XXVI: lorazepam. ( Dundee, JW; George, KA; Lilburn, JK; Nair, SG, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 38 (77.55) | 18.7374 |
| 1990's | 7 (14.29) | 18.2507 |
| 2000's | 4 (8.16) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Izaute, M | 1 |
| Bacon, E | 1 |
| Pogarell, O | 1 |
| Ehrentraut, S | 1 |
| Rüther, T | 1 |
| Mulert, C | 1 |
| Hegerl, U | 1 |
| Möller, HJ | 1 |
| Henkel, V | 1 |
| Pomara, N | 1 |
| Facelle, TM | 1 |
| Roth, AE | 1 |
| Willoughby, LM | 1 |
| Greenblatt, DJ | 1 |
| Sidtis, JJ | 1 |
| Barclay, JK | 1 |
| Hunter, KM | 1 |
| Jones, H | 1 |
| Kothary, SP | 1 |
| Brown, AC | 1 |
| Pandit, UA | 1 |
| Samra, SK | 1 |
| Pandit, SK | 1 |
| Simpson, PJ | 1 |
| Eltringham, RJ | 1 |
| Scharf, MB | 3 |
| Kales, A | 1 |
| Bixler, EO | 1 |
| Jacoby, JA | 1 |
| Schweitzer, PK | 1 |
| Brown, J | 2 |
| Lewis, V | 2 |
| Brown, M | 1 |
| Horn, G | 2 |
| Bowes, JB | 2 |
| Burtles, R | 1 |
| Astley, B | 1 |
| Nielsen-Kudsk, F | 1 |
| Jensen, TS | 1 |
| Magnussen, I | 1 |
| Jakobsen, P | 1 |
| Jensen, PB | 1 |
| Mondrup, K | 1 |
| Petersen, T | 1 |
| Healey, M | 1 |
| Pickens, R | 1 |
| Meisch, R | 1 |
| McKenna, T | 1 |
| Khosla, N | 2 |
| Brocker, N | 2 |
| Goff, P | 1 |
| Korttila, K | 1 |
| Roehrs, T | 1 |
| McLenaghan, A | 1 |
| Koshorek, G | 1 |
| Zorick, F | 1 |
| Roth, T | 1 |
| Lister, RG | 1 |
| File, SE | 1 |
| Fitzal, S | 1 |
| Groll-Knapp, E | 1 |
| Länger, W | 1 |
| Riegler, R | 1 |
| Lysaght, R | 1 |
| Moran, J | 1 |
| Brown, MW | 2 |
| Rose, D | 1 |
| Ahlquist, J | 1 |
| Sebel, PS | 1 |
| Bovill, JG | 1 |
| Wauquier, A | 1 |
| Rog, P | 1 |
| Mallick, JL | 1 |
| Kirkby, KC | 1 |
| Martin, F | 1 |
| Philp, M | 1 |
| Hennessy, MJ | 1 |
| Vidailhet, P | 1 |
| Danion, JM | 1 |
| Kauffmann-Muller, F | 1 |
| Grangé, D | 1 |
| Giersch, A | 1 |
| van der Linden, M | 1 |
| Imbs, JL | 1 |
| Curran, HV | 1 |
| Barrow, S | 1 |
| Weingartner, H | 1 |
| Lader, M | 1 |
| Bernik, M | 1 |
| Barr, J | 1 |
| Zomorodi, K | 1 |
| Bertaccini, EJ | 1 |
| Shafer, SL | 1 |
| Geller, E | 1 |
| Soubrie, P | 1 |
| Simon, P | 1 |
| Boissier, JR | 1 |
| Cormack, RS | 2 |
| Milledge, JS | 1 |
| Hanning, CD | 1 |
| Paymaster, NJ | 1 |
| Mundeleer, P | 1 |
| Dundee, JW | 4 |
| George, KA | 3 |
| Lilburn, JK | 2 |
| Nair, SG | 1 |
| Galloon, S | 1 |
| Gale, GD | 1 |
| Lancee, WJ | 1 |
| Heipertz, W | 1 |
| Vontin, H | 1 |
| Schorer, R | 1 |
| Junger, H | 1 |
| McGowan, WA | 1 |
| McKay, AC | 1 |
| Hegarty, JE | 1 |
| Knopman, D | 1 |
| Henry, DW | 1 |
| Burwinkle, JW | 1 |
| Klutman, NE | 1 |
| Satzger, W | 1 |
| Engel, RR | 1 |
| Ferguson, E | 1 |
| Kapfhammer, H | 1 |
| Eich, FX | 1 |
| Hippius, H | 1 |
| Erickson, KR | 1 |
| Preston, KL | 1 |
| Guarino, JJ | 1 |
| Kirk, WT | 1 |
| Griffiths, RR | 1 |
| Rager, P | 1 |
| Bénézech, M | 1 |
| Dorow, R | 1 |
| Berenberg, D | 1 |
| Duka, T | 1 |
| Sauerbrey, N | 1 |
| Ott, H | 1 |
| Rohloff, A | 1 |
| Aufdembrinke, B | 1 |
| Fichte, K | 1 |
| Gordon, CJ | 1 |
| Pazdur, R | 1 |
| Ziccarelli, A | 1 |
| Cummings, G | 1 |
| Al-Sarraf, M | 1 |
| Kumar, R | 2 |
| Mac, DS | 2 |
| Gabrielli, WF | 1 |
| Goodwin, DW | 2 |
| Pande, AC | 1 |
| Sandyk, R | 1 |
| Magbagbeola, JA | 1 |
1 review available for lorazepam and Amnesia
| Article | Year |
|---|---|
Amnestic disorders. Pathophysiology and patterns of memory dysfunction.
Topics: Adrenocorticotropic Hormone; Age Factors; Amnesia; Brain Injuries; Epilepsy; Humans; Lorazepam; Mult | 1990 |
30 trials available for lorazepam and Amnesia
| Article | Year |
|---|---|
Specific effects of an amnesic drug: effect of lorazepam on study time allocation and on judgment of learning.
Topics: Adult; Amnesia; Anti-Anxiety Agents; Calibration; Double-Blind Method; Female; Humans; Hypnotics and | 2005 |
Dose-dependent retrograde facilitation of verbal memory in healthy elderly after acute oral lorazepam administration.
Topics: Aged; Alleles; Amnesia; Apolipoprotein E4; Apolipoproteins E; Cognition; Cross-Over Studies; Dose-Re | 2006 |
Diazepam and lorazepam compared as sedatives for outpatient third molar surgery.
Topics: Adolescent; Adult; Amnesia; Anesthesia, Dental; Anti-Anxiety Agents; Clinical Trials as Topic; Diaze | 1980 |
A comparison between transient amnesias induced by two drugs (diazepam or lorazepam) and amnesia of organic origin.
Topics: Adult; Amnesia; Anti-Anxiety Agents; Diazepam; Female; Humans; Lorazepam; Male; Memory; Memory, Shor | 1982 |
Lorazepam in children. A double-blind trial comparing lorazepam, diazepam, trimeprazine and placebo.
Topics: Adolescent; Amnesia; Anti-Anxiety Agents; Child; Child, Preschool; Clinical Trials as Topic; Diazepa | 1983 |
Effects of clorazepate, diazepam, lorazepam, and placebo on human memory.
Topics: Administration, Oral; Adult; Amnesia; Anti-Anxiety Agents; Clorazepate Dipotassium; Diazepam; Dose-R | 1983 |
Differential amnestic properties of short- and long-acting benzodiazepines.
Topics: Administration, Oral; Adolescent; Adult; Amnesia; Anti-Anxiety Agents; Clorazepate Dipotassium; Dose | 1984 |
Amnesic effects of lormetazepam.
Topics: Adolescent; Adult; Amnesia; Anti-Anxiety Agents; Attention; Benzodiazepines; Double-Blind Method; El | 1984 |
The nature of lorazepam-induced amnesia.
Topics: Adult; Amnesia; Analysis of Variance; Female; Humans; Learning; Lorazepam; Male; Reading | 1984 |
[Premedication with flunitrazepam, lormetazepam or pethidine-promethazine. Psychometric study of subjective conditions].
Topics: Adult; Amnesia; Anti-Anxiety Agents; Anxiety; Benzodiazepines; Depression; Emotions; Flunitrazepam; | 1983 |
Anterograde amnesia with oral lorazepam.
Topics: Administration, Oral; Adult; Amnesia; Dose-Response Relationship, Drug; Humans; Lorazepam; Male; Mem | 1983 |
A comparison of the amnesic effects of lorazepam in alcoholics and non-alcoholics.
Topics: Adult; Alcoholism; Amnesia; Arousal; Humans; Lorazepam; Male; Memory; Memory, Short-Term; Orientatio | 1993 |
Lorazepam and diazepam effects on memory acquisition in priming tasks.
Topics: Adult; Amnesia; Cognition; Diazepam; Double-Blind Method; Female; Humans; Hypnotics and Sedatives; L | 1994 |
Encoding, remembering and awareness in lorazepam-induced amnesia.
Topics: Adult; Amnesia; Attention; Female; Humans; Learning; Lorazepam; Male; Memory; Mental Recall; Middle | 1995 |
A double-blind, randomized comparison of i.v. lorazepam versus midazolam for sedation of ICU patients via a pharmacologic model.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amnesia; Double-Blind Method; Female; Hemodynamics; Huma | 2001 |
Proceedings: Respiration and amnesia after lorazepam or morphine premedication.
Topics: Amnesia; Anti-Anxiety Agents; Humans; Lorazepam; Morphine; Preanesthetic Medication; Respiration | 1976 |
Evaluation of anxiolytic and amnesic effects of intramuscular lorazepam as a pre-operative medication.
Topics: Adult; Amnesia; Anti-Anxiety Agents; Clinical Trials as Topic; Female; Humans; Injections, Intramusc | 1976 |
Relative amnesic actions of diazepam, flunitrazepam and lorazepam in man.
Topics: Amnesia; Anesthesia; Anti-Anxiety Agents; Diazepam; Female; Flunitrazepam; Humans; Lorazepam; Time F | 1977 |
Comparison of lorazepam and diazepam as premedicants.
Topics: Adult; Amnesia; Anti-Anxiety Agents; Anxiety; Clinical Trials as Topic; Diazepam; Double-Blind Metho | 1977 |
Comparison of the actions of diazepam and lorazepam.
Topics: Amnesia; Anti-Anxiety Agents; Diazepam; Humans; Lorazepam; Middle Aged; Preanesthetic Medication; Ti | 1979 |
Awareness during surgery--a new approach.
Topics: Adult; Amnesia; Anesthesia; Anti-Anxiety Agents; Consciousness; Dose-Response Relationship, Drug; Fe | 1979 |
Unaware learning versus preserved learning in pharmacologic amnesia: similarities and differences.
Topics: Adolescent; Adult; Amnesia; Female; Humans; Learning; Lorazepam; Male; Psychometrics; Reaction Time; | 1991 |
Effects of single doses of alpidem, lorazepam, and placebo on memory and attention in healthy young and elderly volunteers.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Amnesia; Anti-Anxiety Agents; Attention; Cognitio | 1990 |
Evaluation of the abuse potential of methocarbamol.
Topics: Adolescent; Adult; Affect; Amnesia; Analysis of Variance; Dose-Response Relationship, Drug; Humans; | 1989 |
Amnestic effects of lormetazepam and their reversal by the benzodiazepine antagonist Ro 15-1788.
Topics: Adult; Amnesia; Anti-Anxiety Agents; Benzodiazepines; Cognition; Emotions; Female; Flumazenil; Human | 1987 |
Anterograde and retrograde amnesia after lormetazepam and flunitrazepam.
Topics: Amnesia; Amnesia, Retrograde; Anti-Anxiety Agents; Benzodiazepines; Double-Blind Method; Emotions; F | 1988 |
Metoclopramide versus metoclopramide and lorazepam. Superiority of combined therapy in the control of cisplatin-induced emesis.
Topics: Adult; Aged; Amnesia; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Female; Humans; Lor | 1989 |
Anxiolytics and memory: a comparison of lorazepam and alprazolam.
Topics: Adult; Alprazolam; Amnesia; Double-Blind Method; Humans; Lorazepam; Male; Memory; Memory, Short-Term | 1987 |
Anterograde amnesia with oral lorazepam.
Topics: Administration, Oral; Adult; Amnesia; Double-Blind Method; Humans; Lorazepam; Memory; Mental Recall; | 1985 |
A comparison of lorazepam and diazepam as oral premedicants for surgery under regional anaesthesia.
Topics: Administration, Oral; Adult; Aged; Amnesia; Anesthesia, Conduction; Anti-Anxiety Agents; Clinical Tr | 1974 |
18 other studies available for lorazepam and Amnesia
| Article | Year |
|---|---|
Prolonged confusional state following electroconvulsive therapy--diagnostic clues from serial electroencephalography.
Topics: Amnesia; Anticonvulsants; Cognition; Confusion; Depressive Disorder, Major; Electroconvulsive Therap | 2005 |
Time course of antirecall effect of diazepam and lorazepam following oral administration.
Topics: Administration, Oral; Adolescent; Amnesia; Amnesia, Retrograde; Analysis of Variance; Anti-Anxiety A | 1981 |
Lorazepam in intensive care.
Topics: Adolescent; Adult; Aged; Amnesia; Anti-Anxiety Agents; Blood Pressure; Child; Consciousness; Critica | 1981 |
Lorazepam-efficacy, side effects, and rebound phenomena.
Topics: Amnesia; Anti-Anxiety Agents; Humans; Lorazepam; Nausea; Sleep Initiation and Maintenance Disorders; | 1982 |
Pharmacokinetics and bioavailability of intravenous and intramuscular lorazepam with an adjunct test of the inattention effect in humans.
Topics: Adult; Amnesia; Anti-Anxiety Agents; Attention; Biological Availability; Female; Half-Life; Humans; | 1983 |
Clinical effectiveness and untoward effects of new agents and techniques used in intravenous sedation.
Topics: Adult; Amnesia; Analgesics; Anesthesia, Dental; Anesthesia, Intravenous; Anti-Anxiety Agents; Benzod | 1984 |
Amnesia-producing drugs affect hippocampal frequency potentiation.
Topics: Amnesia; Animals; Evoked Potentials; Hippocampus; Humans; Lorazepam; Propranolol; Rats; Scopolamine | 1983 |
Effects of high-dose fentanyl anesthesia on the electroencephalogram.
Topics: Amnesia; Analgesia; Anesthesia, General; Cardiac Surgical Procedures; Electroencephalography; Fentan | 1981 |
An amnesic effect of benzodiazepines in rats?
Topics: Amnesia; Animals; Anti-Anxiety Agents; Avoidance Learning; Chlordiazepoxide; Chlorpromazine; Diazepa | 1976 |
Intramuscular premedication with lorazepam.
Topics: Adult; Age Factors; Aged; Amnesia; Anti-Anxiety Agents; Female; Humans; Injections, Intramuscular; I | 1976 |
The amnesic action of diazepam, flunitrazepam and lorazepam in man.
Topics: Amnesia; Anti-Anxiety Agents; Diazepam; Dose-Response Relationship, Drug; Female; Flunitrazepam; Hum | 1976 |
Studies of drugs given before anaesthesia XXVI: lorazepam.
Topics: Administration, Oral; Adult; Amnesia; Anesthesia; Anti-Anxiety Agents; Female; Humans; Injections, I | 1977 |
Amnesic effects of intravenous diazepam and lorazepam.
Topics: Adult; Amnesia; Anti-Anxiety Agents; Diazepam; Humans; Lorazepam; Mental Recall | 1978 |
[Amnesia after the benzodiazepines flunitrazepam and lorazepam].
Topics: Amnesia; Anti-Anxiety Agents; Flunitrazepam; Humans; Lorazepam; Time Factors | 1978 |
Determination of sedative and amnestic doses of lorazepam in children.
Topics: Administration, Oral; Adolescent; Amnesia; Child; Child, Preschool; Dose-Response Relationship, Drug | 1991 |
[Memory gaps and hypercomplex automatisms after a single oral dose of benzodiazepines: clinical and medico-legal aspects].
Topics: Adult; Amnesia; Anti-Anxiety Agents; Automatism; Bromazepam; Drug Synergism; Ethanol; Female; Flunit | 1986 |
Sublingual lorazepam use.
Topics: Administration, Oral; Adult; Amnesia; Depressive Disorder; Erectile Dysfunction; Humans; Lorazepam; | 1987 |
Transient global amnesia induced by lorazepam.
Topics: Aged; Amnesia; Anxiety; Female; Humans; Lorazepam; Memory, Short-Term; Time Factors | 1985 |